This page lists the order of markers in and around the DMD gene. The markers are
provided in relation to the DMD gene's transcriptional orientation, i.e. from
centromere to telomere. In addition, links are provided to the sequences as
present in GenBank (NCBI). On specific issues, more detailed data can be found
at;
Exon |
DXS nr. |
Probe name |
GenBank |
Map position |
Reference |
|
DXS1258 |
|
|
DXS1268 |
|
|
DXS84 |
754 |
Dp427l promoter /
exon 1 |
|
|
D32048 |
|
|
SfiI-A |
|
|
5'DYS-III |
AF209165 |
11.8 kb 5' Dp427b exon 1 |
Feener
(1991) |
|
|
5'DYS-I |
AF209163 |
3.5 kb 5' Dp427b exon 1 |
Feener
(1991) |
|
DXS1242 |
5'DYS-II / sWXD2450 |
AF209164 |
1.2 kb 5' Dp427b exon 1 |
Feener
(1991) |
Dp427c promoter/exon
1 |
|
|
L01538,
M59228,
X15148 |
|
Kunkel, Boyce |
intron 1b |
|
5'DYS-IV |
AF209166 |
4.3 kb 3' Dp427b exon 1 |
Feener
(1991) |
|
SfiI-B |
|
89 kb 5' of Dp427m exon 1 |
|
(c.-8043(AC)16_30) |
5'DYS MSB / sWXD2452 |
|
8 kb 5' of Dp427m exon 1 |
Oudet
(1991) |
Dp427m promoter/exon 1
|
|
|
AF213401
(primer 1F/1R X65341
/ X65342),
AF054599
(L1-insert), M32058 |
40 kb 3' Dp427b + 97 kb 5' Dp427m |
Beggs, Abbs |
intron 1 |
DXS142 |
pERT84-1 |
L37425 |
13 kb 3' of Dp427m exon 1 |
Roberts, Koenig |
DXS1243
(c.31+15515(AC)8_24) |
5'-5n1 / 5'DYS MSA |
X75920 |
15.4 kb 3' Dp427m exon 1 |
King
(1995), Oudet
(1991) |
Dp427p promoter/exon
1 |
|
|
S81419,
S64152 |
82 kb 3' of Dp427m exon 1 |
Gorecki |
intron 1 |
|
5'-5n3 |
X75801
(NOTE: not contiguous sequence - 3' segment maps
downstream) |
36 kb 3' exon 2
(5' part in intron 1) |
King
(1994), King
(1995) |
|
exon 'X' |
L06900 |
50 kb 3' of Dp427p exon 1 |
Roberts |
exon 2
|
|
|
AF213402 |
|
(Leiden unp.) |
intron 2
|
|
5'-5n3 |
X75801
(NOTE: not contiguous sequence - 5' segment maps
upstream) |
|
King
(1994), King
(1995) |
DXS272 |
J47 |
|
|
Smith |
exon 3
|
|
|
AF213403
(primer 3F/3R X65343
/ X65344) |
|
Beggs, Abbs |
intron 3
|
|
|
|
|
|
exon 4
|
|
|
AF213404 |
|
Chamberlain, Abbs |
intron 4
|
|
5'-5n4 |
X77678
|
8.4 kb 5' exon 5 |
King
(1995) |
exon 5
|
|
|
AF213405 |
|
(Leiden unp.) |
intron 5
|
|
HH1 |
|
|
|
exon 6
|
|
|
AF213406, (primer 6F/6R X65345
/ X65346) |
|
Beggs, Abbs |
intron 6
|
|
|
|
|
|
exon 7
|
|
|
AF213407 |
|
(Leiden unp.) |
intron 7
(detailed description) |
|
t(X;21) intron 7 |
A05312,
L08092,
M18024 |
|
McNaughton |
|
DMDSTR07A |
|
22 kb 3' exon 7 |
DB: Leiden |
|
DMDSTR07B |
|
23 kb 3' exon 7 |
DB: Leiden |
|
XJ5.1 |
|
30 kb 3' of exon 7 |
McNaughton |
DXS230 |
XJ1.2 / HIP25 |
|
45 kb 3' of exon 7 |
McNaughton |
DXS206 |
XJ1.1 |
|
55 kb 3' of exon 7 |
McNaughton |
XJ2.3 |
|
60 kb 3' of exon 7 |
McNaughton |
XJ8.1 |
|
100 kb 3' of exon 7 |
XJ10.2 |
|
110 kb 3' of exon 7 |
DXS164
(in GDB) |
pERT87-42 |
|
23 kb 5' exon 8 |
Monaco, Smith |
pERT87-37 |
|
20 kb 5' exon 8 |
Monaco |
pERT87-32 |
|
17 kb 5' exon 8 |
Monaco |
exon 8
|
|
|
AF213408,
M23261,
X06293,
Y00494 |
|
Chamberlain, Abbs |
intron 8
|
|
|
|
|
McNaughton |
exon 9
|
|
|
AF213409 |
intron
9
|
|
|
|
exon
10
|
|
|
AF213410 |
intron
10
|
|
|
|
|
|
exon
11
|
|
|
AF213411 |
|
|
intron
11
|
DXS164
(in GDB) |
pERT87-28 |
Y13187 |
14 kb 3' exon 11 |
Monaco |
SfiI-C |
|
20 kb 3' exon 11 |
(Leiden unp.) |
pERT87-23 |
|
21 kb 3' exon 11 |
Monaco |
exon
12
|
|
|
AF213412, I07692 |
|
Chamberlain |
intron
12
|
DXS164
(in GDB) |
pERT87-12 |
|
14 kb 3' exon 12 |
Monaco |
exon
13 |
|
|
AF213413, X64610
/ X64612
(JBir-junction), (primer 13F/13R X65347
/ X65348)
|
|
Beggs, Abbs |
intron
13
|
DXS164
(in GDB) |
pERT87-1 |
|
5 kb 3' exon 13 |
Monaco |
pERT87-16 |
|
6 kb 3' exon 13 |
Monaco |
pERT87-14 |
|
18 kb 3' exon 13 |
Monaco |
pERT87-8 |
L05531 |
19 kb 3' exon 13 |
Roberts, Monaco |
exon
14
|
|
|
AF213414 |
|
intron
14
|
|
|
|
exon
15
|
|
|
AF213414 |
intron
15
|
DXS164
(in GDB) |
pERT87-4 |
M36671 |
1 kb 3' exon 15 |
Monaco |
exon
16
|
|
|
AF213415 |
|
Kunkel |
intron
16
|
|
|
S90704,
S90696,
X64608,
X64611 |
exon
17
|
|
|
AF213416,
L05532,
X13045,
X63691 |
|
Chamberlain |
intron
17 |
DXS164
(in GDB) |
pERT87-15 |
L05532,
X13045,
X63691 |
1 kb 3' exon 17 |
Roberts, Monaco |
pERT87-13 |
|
8 kb 3' exon 17 |
Monaco |
pERT87-22 |
|
10 kb 5' exon 18 |
Monaco |
exon
18
|
|
|
AF213417 |
|
(Leiden unp.) |
intron
18
|
DXS164
(in GDB) |
pERT87-27 |
|
10 kb 3' exon 18 |
Monaco |
exon 19
|
DXS164
(in GDB) |
pERT87-25 |
M36673,
M55699 |
|
Chamberlain, Abbs |
intron 19
|
DXS164
(in GDB) |
pERT87-25 |
|
3 kb 3' exon 19 |
Monaco |
exon 20
|
|
|
AF213418 |
|
(Leiden unp.) |
intron 20
|
DXS164
(in GDB) |
pERT87-30 |
|
7 kb 3' exon 20 |
Monaco |
pERT87-41 |
AL031542 |
20 kb 3' exon 20 |
Monaco |
exon 21
|
|
|
AF213419 |
|
(Leiden unp.) |
intron 21
|
|
|
|
|
|
exon 22
|
|
|
AF213420 |
|
(Leiden unp.) |
intron 22
|
|
|
|
|
|
exon 23
|
|
|
L05636,
L11637 |
|
(Leiden unp.) |
intron 23
|
|
|
|
|
|
exon 24 |
|
|
L05637,
L11638 |
intron 24
|
|
|
|
|
|
exon 25
|
|
|
L05638,
L11639 |
intron 25
|
|
5'-7n4 |
X77677
|
1.5 kb 5' exon 26 |
King
(1995) |
intron 25-40 |
DXS271 |
SK1 |
|
|
(Leiden unp.) |
exon 26
|
|
|
L05639,
S43366,
S71486 |
|
(Leiden unp.) |
intron 26
|
|
|
|
|
|
exon 27
|
|
|
AF213421,
AB006975,
L05650 |
intron 27
|
|
|
AL031542 |
|
|
exon 28
|
|
|
L05640 |
intron 28
|
|
|
|
|
|
exon 29
|
|
|
L05641 |
|
(Leiden unp.) |
intron 29
|
|
SfiI-D |
|
5 kb 3' exon 29 |
|
Dp260 promoter/exon 1 |
|
|
L05642,
U27203 |
directly 5' exon 30 |
|
exon 30
|
|
|
L05642 |
|
|
intron 30
|
|
|
|
exon 31
|
|
|
AF213422 |
intron 31
|
|
|
|
|
|
exon 32
|
|
|
AF213423,
L41643 |
|
|
intron 32
|
|
|
|
exon 33
|
|
|
AF213424 |
intron 33
|
|
|
|
|
|
exon 34 |
|
|
L05643 |
|
|
intron
34
|
|
|
|
|
exon 35
|
|
|
AF213425 |
|
|
intron 35
|
|
|
|
exon 36
|
|
|
AF213426,
X64608 |
intron 36
|
|
|
|
|
|
exon 37
|
|
|
AF213427 |
|
|
intron 37
|
|
|
|
exon 38
|
|
|
L05644 |
intron 38
|
|
|
|
|
|
exon 39
|
|
|
L05645 |
|
|
intron 39
|
|
|
|
|
|
exon 40
|
|
|
AF213428,
L05646 |
|
(Leiden unp.) |
intron 40
|
|
|
|
|
|
exon 41
|
|
|
AF213429 |
|
Kunkel |
intron 41
|
|
SfiI-E |
|
5 kb 5' of exon 42 |
|
exon 42
|
|
|
AF213430 |
|
Kunkel |
intron 42
|
|
SfiI-E' |
|
|
(Leiden unp.) |
exon 43
|
|
|
AF213431, L41634,
(primer 43F/43R X65349
/ X65350) |
|
Beggs, Abbs |
intron 43
|
DXS270 |
JBir |
X64612
(JBir junction), X64609,
X64611,
M87299,
AF213432
|
just 3' of exon 43 |
Koenig |
exon 44
|
|
|
JdD44,
S61546,
U94396,
X13046 |
|
Chamberlain |
intron 44
|
DXS1238 |
STR-44 |
AF209157, M81257
|
13.8 kb 3' exon 44 |
Clemens
(1991) |
|
IVS44SK12 |
|
50 kb 3' exon 44 |
Kochling
(1995) |
|
IVS44SK21 |
X77644
|
50 kb 3' exon 44 |
Kochling
(1995) |
Dp140 promoter/exon
1 |
|
|
Dp140 promoter/exon
1 (IVS44SK12, IVS44SK21), U90310, L35854 |
50 kb 3' exon 44 |
Lidov |
intron 44
|
DXS1219 |
AFM297yd1 |
Z24187 |
|
Dib
(1996) |
|
|
M65036, M65035 |
|
|
DXS269
(in GDB) |
|
M86524
(P20-CA) |
5-10 kb 5' of P20b |
(den Dunnen, unpl.) |
P20a |
|
40-45 kb 5' of exon 45 |
(den Dunnen, unpl.) |
P20 (deletion junction
of P20a / P20b) |
AF209182 |
|
(den Dunnen, unpl.) |
|
Z11838
/ Z22650
(P20-Alu RFLP / Alu insert) |
directly upstream of P20b (in 3'-5' orientation) |
Blonden |
P20b |
AF209189 |
~8 kb 5' of exon 45 |
(den Dunnen, unpl.) |
exon 45
|
|
|
X13048,
X15495 |
|
Chamberlain |
intron 45
|
DXS1237
(in GDB) |
STR-45.1 |
AF209158 |
1.2 kb 3' exon 45 |
Clemens |
|
STR-45.2 |
AF209159 |
.. kb 3' exon 45 |
(Chamberlain, unpl.) |
exon 46
|
|
|
I07712 |
|
Beggs |
intron 46
|
|
|
|
|
|
exon 47
|
|
|
AF213433, L41635,
(primer 47F/47R X65351
/ X65352) |
|
Beggs, Abbs |
intron 47
|
|
|
|
|
|
exon 48
|
|
|
X13047,
X54820,
L41635 |
|
Chamberlain, Abbs |
intron 48
|
|
SfiI-F |
|
2.8 kb 3' exon 48 |
|
DXS997
(in GDB) |
AFM217xa5 |
Z16983
, M65036 |
3.6 kb 3' exon 48 |
Dib
(1996) |
|
STR-48 |
AF209160 |
29 kb 3' exon 48 |
|
exon 49
|
|
|
AF213434,
(primer 49F/49R X65359
/ X65360) |
|
Beggs |
intron 49
|
DXS1236 |
STR-49 |
AF209161 |
intron 49 |
Clemens |
exon 50
|
|
|
AF213435
(primer 50F/50R X65353
/ X65354) |
|
Beggs, Abbs |
intron 50
|
DXS1235
=
DXS1067 |
STR-50 |
AF209162, Z23710 |
5.5 kb 5' exon 51 |
Clemens,
Dib
(1996) |
AFM234vg7 |
DXS239 |
|
GMGX11 |
|
|
exon 51
|
|
|
AF213436, X51934,
M65035,
X16089 |
intron 51
|
DXS1036
(in GDB) |
AFM072h3 |
Z23325,
M62511 |
|
Dib
(1996) |
exon 52
|
|
|
AF213437,
(primer 52F/52R X65355
/ X65356) |
intron 52
|
|
|
|
exon 53
|
|
|
AF213438 |
intron 53
|
|
|
|
exon 54 |
|
|
AF213439 |
intron 54
|
|
SfiI-G |
|
|
|
exon 55
|
|
|
AF213440, L37431 |
|
Nobile, (Leiden unp.) |
intron 55
|
|
|
|
|
|
Dp116 promoter/exon 1 |
|
|
S62618 |
|
|
exon 56
|
|
|
L05647 |
intron 56
|
|
|
|
|
|
exon 57
|
|
|
L04186 |
intron 57
|
|
|
|
|
|
exon 58
|
|
|
L05648 |
intron 58
|
|
|
|
|
|
exon 59
|
|
|
L05649 |
intron 59 |
DXS1241 |
DMD1-2c |
X55151 |
|
Powell, (den Dunnen,
unpl.) |
exon 60
|
|
|
Z11860,
M86884,
(primer 60F/60R X65357
/ X65358) |
intron 60 |
DXS268 |
J66 VNTR |
Z11861 |
just 3' of exon 66 |
van Ommen |
|
SfiI-H, SfiI-I |
|
|
|
exon 61
|
|
|
M86885 |
intron 61 |
|
SfiI-I' |
|
|
|
exon 62 |
|
|
M86886 |
intron 62
|
|
|
|
|
|
Dp71/40 promoter/exon
1 |
|
|
S42212 |
8 kb 5' exon 63 |
|
exon 63
|
|
|
M86887 |
|
|
intron 63
|
|
STR62/63 |
|
|
Taylor et al. (unpublished) |
DXS1214
(in GDB) |
AFM283wg9 |
Z24023 |
|
Dib
(1996) |
|
|
M62510,
M62512,
M62513 |
|
|
exon 64
|
|
|
AF213441, M86888 |
|
|
intron 64
|
|
STRHI |
|
|
(Cockburn, unpl.) |
exon 65
|
|
|
M86889 |
|
|
intron 65
|
|
|
|
|
|
exon 66
|
|
|
M86890 |
|
|
intron 66
|
|
|
|
|
|
exon 67
|
|
|
M86891 |
|
|
intron 67
|
|
|
|
|
|
exon 68
|
|
|
M86892 |
|
|
intron 68
|
|
|
|
|
|
exon 69
|
|
|
M86893 |
|
|
intron 69
|
|
|
|
|
|
exon 70
|
|
|
AF213442, M86894,
X15149 |
|
|
intron 70 |
|
|
|
|
|
exon 71
|
|
|
M86895 |
|
|
intron 71
|
|
|
|
|
|
exon 72
|
|
|
M86896 |
|
|
intron 72
|
|
|
|
|
|
exon 73
|
|
|
M86897 |
|
|
intron 73
|
|
|
|
|
|
exon 74
|
|
|
M86898 |
|
|
intron 74
|
|
|
|
|
|
exon 75
|
|
|
AF213443, M86899 |
|
|
intron 75
|
|
|
|
|
|
exon 76
|
|
|
M86900 |
|
|
intron 76
|
|
|
|
|
|
exon 77
|
|
|
M86901 |
|
|
intron 77
|
|
|
|
|
|
exon 78
|
|
|
M86902 |
|
|
intron 78
|
|
|
AF213444 |
|
|
exon 79
|
|
|
M86903,
M86904,
M18533 |
|
|
DXS1234 |
3'DYS MSC |
|
exon 79 (11,550) |
Oudet
(1990), Beggs
(1990) |
|
MP1S |
|
exon 79 (12,000) |
Roberts
(1989) |
DXS503 |
MP1P |
|
exon 79 (12,100) |
Abbs
(1990), Roberts
(1989) |
|
MP1Q |
|
exon 79 (12,620) |
Abbs
(1990), Roberts
(1989) |
|
DXS726 |
FT-1 |
|
9.5 kb 3' exon 79 |
Worley
(1992) |
|
|
3'-19n8 |
X75580 |
200 kb 3'
of exon 79 |
King
(1994), King
(1995) |
|
DXS992
|
AFM184xg5 |
Z16803 |
> 200 kb 3'
of exon 79 |
(den Dunnen, unp.) |
|
DXS985
|
AFM112xf2 |
Z16589 |
>200 kb 3'
of exon 79 |
Dib
(1996) |
GKD |
|
DXS1065, DXS1202 |
|
|
DXS1028, DXS1061 |
|
AHC |
|
DXS319 |
QST59 |
|
|
Worley |
|
DXS727 |
YHX39R |
|
|
Worley |
|
DXS28 |
C7 |
|
DXS67 |
B24 |
|
DXS68 |
L1-4 |
|
DXS41 |
99.6 |
|
DXS43 |
D2 |