LOCUS       HSBTSAR1     1447 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 1 and 5' regulatory
            sequence.
ACCESSION   U63796
NID         g1732547
KEYWORDS    .
SEGMENT     1 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     exon            <1147..1179
                     /gene="LGMD 2E"
                     /number=1
                     /product="beta-sarcoglycan"
BASE COUNT      330 a    378 c    466 g    273 t
ORIGIN      
        1 aagcttagga attaaggact agaagatagg aactcagaat cagttaaaag cccagttgtg
       61 caaattgatc aatgagacca caggcagaat attaacacag agccttactg ctgactcctg
      121 catcattggg ctttaactta gaattttcct gcctaaaatg catgtttgtc ccacagactc
      181 agagaggagt gagtctagag atatgagtca agtggttcca gcatttagga aaaaagaaat
      241 gcagagagac tgatgaccag ctaggtactg actcccactg aattagacag tactagggcc
      301 caaaggtgct tattagaagt gattcagcta catgaggaac agttgctatt gacttcactg
      361 catttttttt cagctaaaat aattattgga ttatatctac aacagggaac aatgaatgtc
      421 tactcaagta actcgtacat ttgagtggct tcccggtgtt cagtaaatgt ccgttcaatt
      481 aggttcccga ggatatacat ggtaacacta tctccaacac taaatgaaaa atccatcccc
      541 agtatcgcag gataaaaaca tcagacttca taggcctccg aagtcaagca gcccgaagga
      601 ttcaacgtcc tccttgagga ctctcagtct tcaagactcc agccacctaa gtgaccactc
      661 gttcacttct gcccacgcag tcaccacgcc ggtccgcgtc cacttgtggt ctcgatatcg
      721 gcccctccca ccctagccaa ggagaccttg gtccgagaaa caaagagagc ctcacagctc
      781 cggatggcac cgatctttca gcgatgggga aaaaagggga aggggagaag cgtcctcgat
      841 ttttgagggt gccctttctg aggaatctgc aggcggcccg gggtggagcg gaatccccat
      901 aggccccttc tggcccctgt gcaatacaac gcgccccagg ccaaggtcct aggtgcaggg
      961 gccgccgcag agcctgagcc cgcagggctg ggatgcgggt cgtcagggat gcgggctggg
     1021 gaggggaggg tgtgagcagc gggtgccccc agtccccgcc agggcgcaag cgcaggcgcg
     1081 cagggtgcgg tcgcggaggg gcgggcacag tcgggcgggg agctcggcgg cggcgggcgc
     1141 gggaagatgg cggcagcggc ggcggcggct gcagaacagg tctgtgagta ccgccgcggc
     1201 cgcgggctgg atgagcgggg gaggcccctt cctgccggct gggcccgcgg gagccctggc
     1261 cgggggtgcg gggggcgcgg gccgcagggt ctgggttcgg cggggccgat cggggcgggg
     1321 cggggcggga ggaactgtgc cccgccgagg atgctggcac aagctaggga ccaggagcca
     1381 ggggcggcct cgggctcggc ccggcctggc tgatcctcgg agggggtgag gaggggtctc
     1441 cttccgg
//
LOCUS       HSBTSAR2      313 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 2.
ACCESSION   U63797
NID         g1732548
KEYWORDS    .
SEGMENT     2 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     exon            62..271
                     /gene="LGMD 2E"
                     /number=2
                     /product="beta-sarcoglycan"
BASE COUNT       99 a     49 c     72 g     93 t
ORIGIN      
        1 tagataaatg cacccaaacg agagggtata gctgttccat tatgttgtat ttcattttta
       61 gcaaagttcc aatggtcctg taaagaagtc catgcgtgag aaggctgttg agagaaggag
      121 tgtcaataaa gagcacaaca gtaactttaa agctggatac attccgattg atgaagatcg
      181 tctccacaaa acagggttga gaggaagaaa gggcaattta gccatctgtg tgattatcct
      241 cttgtttatc ctggctgtca tcaatttaat agtgagtatt tgtaagaata ctcattttaa
      301 ttgccatggg gaa
//
LOCUS       HSBTSAR3      312 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 3.
ACCESSION   U63798
NID         g1732549
KEYWORDS    .
SEGMENT     3 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 312)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..312
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     exon            82..267
                     /gene="LGMD 2E"
                     /number=3
                     /product="beta-sarcoglycan"
BASE COUNT       92 a     57 c     73 g     90 t
ORIGIN      
        1 tggtgataat attttctact tgttttccaa ttacattaaa tgtatgcggc ctaccaacag
       61 cggacttgtg ttctttttca gataacactt gttatttggg ccgtgattcg cattggacca
      121 aatggctgtg atagtatgga gtttcatgaa agtggcctgc ttcgatttaa gcaagtatct
      181 gacatgggag tgatccaccc tctttataaa agcacagtag gaggaaggcg aaatgaaaat
      241 ttggtcatca ctggcaacaa ccagcctgta agttgccaca ttaactgaaa gaaatgcaaa
      301 caggagaggg gc
//
LOCUS       HSBTSAR4      298 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 4.
ACCESSION   U63799
NID         g1732550
KEYWORDS    .
SEGMENT     4 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     exon            68..259
                     /gene="LGMD 2E"
                     /number=4
                     /product="beta-sarcoglycan"
BASE COUNT       97 a     43 c     58 g    100 t
ORIGIN      
        1 attgttcagg aattttgttt gcagtcttct ttgaaaatat attcacaata aactgttttt
       61 tttgaagatt gtttttcagc aagggacaac aaagctcagt gtagaaaaca acaaaacttc
      121 tattacaagt gacatcggca tgcagttttt tgacccgagg actcaaaata tcttattcag
      181 cacagactat gaaactcatg agtttcattt gccaagtgga gtgaaaagtt tgaatgttca
      241 aaaggcatct actgaaaggg tatgatttat tggctttgtt ttactaatgg gagagaat
//
LOCUS       HSBTSAR5      256 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 5.
ACCESSION   U63800
NID         g1732551
KEYWORDS    .
SEGMENT     5 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 256)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..256
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     exon            81..212
                     /gene="LGMD 2E"
                     /number=5
                     /product="beta-sarcoglycan"
BASE COUNT       75 a     33 c     52 g     96 t
ORIGIN      
        1 gcttctattt ctctatctct gataacaatt ctcacattaa tttagaaact ctttttagta
       61 cttgtttttt aaattttcag attaccagca atgctaccag tgatttaaat ataaaagttg
      121 atgggcgtgc tattgtgcgt ggaaatgaag gtgtattcat tatgggcaaa accattgaat
      181 ttcacatggg tggtaatatg gagttaaagg cggtgagtat tcttttaaga gcttaagaga
      241 attattaggt tcttgg
//
LOCUS       HSBTSAR6      314 bp    DNA             PRI       17-DEC-1996
DEFINITION  Human beta-sarcoglycan (LGMD 2E) gene, exon 6, and complete cds.
ACCESSION   U63801
NID         g1732552
KEYWORDS    .
SEGMENT     6 of 6
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Bonnemann,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-1996) Genetics, Children's Hospital, 300 Longwood
            Ave., Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Homo sapiens"
                     /chromosome="4"
                     /map="4q12"
     mRNA            join(U63796:<1147..1179,U63797:62..271,U63798:82..267,
                     U63799:68..259,U63800:81..212,73..>276)
                     /gene="LGMD 2E"
     CDS             join(U63796:1147..1179,U63797:62..271,U63798:82..267,
                     U63799:68..259,U63800:81..212,73..276)
                     /gene="LGMD 2E"
                     /codon_start=1
                     /product="beta-sarcoglycan"
                     /db_xref="PID:g1732554"
                     /translation="MAAAAAAAAEQQSSNGPVKKSMREKAVERRSVNKEHNSNFKAGY
                     IPIDEDRLHKTGLRGRKGNLAICVIILLFILAVINLIITLVIWAVIRIGPNGCDSMEF
                     HESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVENNKT
                     SITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNI
                     KVDGRAIVRGNEGVFIMGKTIEFHMGGNMELKAENSIILNGSVMVSTTRLPSSSSGDQ
                     LGSGDWVRYKLCMCADGTLFKVQVTSQNMGCQISDNPCGNTH"
     exon            73..>276
                     /gene="LGMD 2E"
                     /number=6
                     /product="beta-sarcoglycan"
BASE COUNT       87 a     77 c     67 g     83 t
ORIGIN      
        1 agttttgttt actgactttg ttctgtaccc cctcatggag gtaaataaat catattacta
       61 ttctcctaat aggaaaacag tatcatccta aatggatctg tgatggtcag caccacccgc
      121 ctacccagtt cctccagtgg agaccagttg ggtagtggtg actgggtacg ctacaagctc
      181 tgcatgtgtg ctgatgggac gctcttcaag gtgcaagtaa ccagccagaa catgggctgc
      241 caaatctcag acaacccctg tggaaacact cattaaaaga acccagaggt caccaacatg
      301 tttatatctt gact
//


