LOCUS       HSU31116     2037 bp    mRNA            PRI       09-FEB-1996
DEFINITION  Human beta-sarcoglycan A3b mRNA, complete cds.
ACCESSION   U31116
NID         g1054894
KEYWORDS    .
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2037)
  AUTHORS   Bonnemann,C.G., Modi,R., Noguchi,S., Mizuno,Y., Yoshida,M.,
            Gussoni,E., McNally,E.M., Duggan,D., Angelini,C., Hoffman,E.P.,
            Ozawa,E. and Kunkel,L.M.
  TITLE     Beta-sarcoglycan (A3b) mutations cause autosomal recessive muscular
            dystrophy with loss of the sarcoglycan complex
  JOURNAL   Nature Genet. 11 (3), 266-273 (1995)
  MEDLINE   96042573
REFERENCE   2  (bases 1 to 2037)
  AUTHORS   Bonnemann,C.G.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JUL-1995) Carsten G. Bonnemann, Genetics, Children's
            Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
FEATURES             Location/Qualifiers
     source          1..2037
                     /organism="Homo sapiens"
                     /dev_stage="adult"
                     /tissue_type="muscle"
                     /chromosome="4"
                     /map="4q12"
     5'UTR           <1..42
     CDS             43..999
                     /note="A3b; member of the sarcoglycan complex; 43 kDa
                     dystrophin-associated glycoprotein"
                     /codon_start=1
                     /product="beta-sarcoglycan"
                     /db_xref="PID:g1054895"
                     /translation="MAAAAAAAAEQQSSNGPVKKSMREKAVERRSVNKEHNSNFKAGY
                     IPIDEDRLHKTGLRGRKGNLAICVIILLFILAVINLIITLVIWAVIRIGPNGCDSMEF
                     HESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVENNKT
                     SITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNI
                     KVDGRAIVRGNEGVFIMGKTIEFHMGGNMELKAENSIILNGSVMVSTTRLPSSSSGDQ
                     LGSGDWVRYKLCMCADGTLFKVQVTSQNMGCQISDNPCGNTH"
     3'UTR           999..2037
BASE COUNT      638 a    360 c    429 g    610 t
ORIGIN      
        1 ggacagtcgg gcggggagct cggcggcggc gggcgcggga agatggcggc agcggcggcg
       61 gcggctgcag aacagcaaag ttccaatggt cctgtaaaga agtccatgcg tgagaaggct
      121 gttgagagaa ggagtgtcaa taaagagcac aacagtaact ttaaagctgg atacattccg
      181 attgatgaag atcgtctcca caaaacaggg ttgagaggaa gaaagggcaa tttagccatc
      241 tgtgtgatta tcctcttgtt tatcctggct gtcatcaatt taataataac acttgttatt
      301 tgggccgtga ttcgcattgg accaaatggc tgtgatagta tggagtttca tgaaagtggc
      361 ctgcttcgat ttaagcaagt atctgacatg ggagtgatcc accctcttta taaaagcaca
      421 gtaggaggaa ggcgaaatga aaatttggtc atcactggca acaaccagcc tattgttttt
      481 cagcaaggga caacaaagct cagtgtagaa aacaacaaaa cttctattac aagtgacatc
      541 ggcatgcagt tttttgaccc gaggactcaa aatatcttat tcagcacaga ctatgaaact
      601 catgagtttc atttgccaag tggagtgaaa agtttgaatg ttcaaaaggc atctactgaa
      661 aggattacca gcaatgctac cagtgattta aatataaaag ttgatgggcg tgctattgtg
      721 cgtggaaatg aaggtgtatt cattatgggc aaaaccattg aatttcacat gggtggtaat
      781 atggagttaa aggcggaaaa cagtatcatc ctaaatggat ctgtgatggt cagcaccacc
      841 cgcctaccca gttcctccag tggagaccag ttgggtagtg gtgactgggt acgctacaag
      901 ctctgcatgt gtgctgatgg gacgctcttc aaggtgcaag taaccagcca gaacatgggc
      961 tgccaaatct cagacaaccc ctgtggaaac actcattaaa agaaccccag aggtcaccaa
     1021 catgtttata tcttgacttg acttttttat gcatgcaaat cattgttttt acagagtttg
     1081 tgataactca taattatttt aatggcagag cactgctgta tctgttttat ggtctacata
     1141 gttaaaatct tctcagagag cctaaattct aatacatttt attaatttat actaatcttc
     1201 atatttactg ttctctaaaa taattatgag aagcaaataa aatccaaagt catgtttaaa
     1261 gacgtgtttt taaaattcca ctatcccttt tctaaaggtt aaaggtctga agcagctgtt
     1321 tagattcact gtaagtaaac tttggtaact ctaatgggga tagacccact taagatattt
     1381 aaaaaggtat ggcatcagcg tttcatgctc tgccttttag cttctaaaag gaaagatgca
     1441 gatttctagt gcattaagcc tgagccatat tctcacatgc aagtgaagtc attaaagaac
     1501 tttacatatg tgagatagaa acaatggttc cttagttttg cactgggaag aaaatatttt
     1561 gtaaaagaat gtttatttga aataatgata actatcaatt gttcacaatg tggtggaaat
     1621 taaaacacca tctcagcttt aacttttaaa taataatgat aactatcttt attgagcatc
     1681 ttctacatcc taggcattgt cctaggcatt gcatgtttat atccccaatt ctcaccacaa
     1741 ccctgcaagt aggtggtatt atccaagttt tacccattaa gaaactgaag atcagagaag
     1801 ttaagaaact tgctcaacat catatagtaa gtagcagagt tgggattgga attccttttt
     1861 tttttttttt aactagagta agcatatctg ttttgtttga ttctcatctt cttaggtaag
     1921 tttaaattaa cctttgttca tctttctaga gttttaaata attaaaaagt cagtgcagag
     1981 agtgaaaaca acatggcatt tggaatcaag tacatccagg tttgagtcat gcctgaa
//


