WNK lysine deficient protein kinase 1 (WNK1) - coding DNA reference sequence

(used for mutation description)

(last modified July 13, 2012)


This file was created to facilitate the description of sequence variants in the WNK1 gene based on a coding DNA reference sequence following the HGVS recommendations.

The sequence was taken from NG_007984.2, covering WNK1 transcript NM_213655.4.


Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                     .         .         .         .                g.4907
                  ccggcccttcgcctctgggcgatgggcgacctgtgaggccggt       c.-601

 .         .         .         .         .         .                g.4967
 ccccatcgctgggggcgcgtgtgggaggaggcggccgcccgagtgaccgggagccgggcc       c.-541

 .         .         .         .         .         .                g.5027
 gcggccttccctcgcccgcctcggcccctcccactcctctgccccggggccgccaccgcc       c.-481

 .         .         .         .         .         .                g.5087
 cgggcgtcggacctggtcccgtgctcgcggtgccgccgccctctgggcctagcccgccca       c.-421

 .         .         .         .         .         .                g.5147
 gctcggcgagcggcggcagtgggagccgcgtccgccgcatccgcctcgactcggtgccgg       c.-361

 .         .         .         .         .         .                g.5207
 cccctggccctcccctcatgactgcggcgcctctgctgccaccgcccgcccggccgccgc       c.-301

 .         .         .         .         .         .                g.5267
 tcgccgcaggatggatgcggaccgtgcggcgctaacccccgtggctcagctcccgaatcg       c.-241

 .         .         .         .         .         .                g.5327
 cccgccttcgagccctcctcgtgagccgcagcagcctcggtgccagcccccgccgcagct       c.-181

 .         .         .         .         .         .                g.5387
 gggcccagcggtccgcctgtccctcgttgcggcttgtcggtgctgagtgaggcgtcgtcc       c.-121

 .         .         .         .         .         .                g.5447
 gggtcggcgcgaacccgcccggccgcggttccctgcagacctctgcgcgggcggctcggc       c.-61

 .         .         .         .         .         .                g.5507
 ccttcacgcccttttcgttcacgaatccgagcccgctcgcctctctccagcgaaccgacc       c.-1

          .         .         .         .         .         .       g.5567
 ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCG       c.60
 M  S  G  G  A  A  E  K  Q  S  S  T  P  G  S  L  F  L  S  P         p.20

          .         .         .         .         .         .       g.5627
 CCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGA       c.120
 P  A  P  A  P  K  N  G  S  S  S  D  S  S  V  G  E  K  L  G         p.40

          .         .         .         .         .         .       g.5687
 GCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT       c.180
 A  A  A  A  D  A  V  T  G  R  T  E  E  Y  R  R  R  R  H  T         p.60

          .         .         .         .         .         .       g.5747
 ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTC       c.240
 M  D  K  D  S  R  G  A  A  A  T  T  T  T  T  E  H  R  F  F         p.80

          .         .         .         .         .         .       g.5807
 CGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTT       c.300
 R  R  S  V  I  C  D  S  N  A  T  A  L  E  L  P  G  L  P  L         p.100

          .         .         .         .         .         .       g.5867
 TCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC       c.360
 S  L  P  Q  P  S  I  P  A  A  V  P  Q  S  A  P  P  E  P  H         p.120

          .         .         .         .         .         .       g.5927
 CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCT       c.420
 R  E  E  T  V  T  A  T  A  T  S  Q  V  A  Q  Q  P  P  A  A         p.140

          .         .         .         .         .         .       g.5987
 GCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACC       c.480
 A  A  P  G  E  Q  A  V  A  G  P  A  P  S  T  V  P  S  S  T         p.160

          .         .         .         .         .         .       g.6047
 AGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG       c.540
 S  K  D  R  P  V  S  Q  P  S  L  V  G  S  K  E  E  P  P  P         p.180

          .         .         .         .         .         .       g.6107
 GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAG       c.600
 A  R  S  G  S  G  G  G  S  A  K  E  P  Q  E  E  R  S  Q  Q         p.200

          .         .         .         .         .         .       g.6167
 CAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTT       c.660
 Q  D  D  I  E  E  L  E  T  K  A  V  G  M  S  N  D  G  R  F         p.220

          .         .         .         .         .         .       g.6227
 CTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC       c.720
 L  K  F  D  I  E  I  G  R  G  S  F  K  T  V  Y  K  G  L  D         p.240

          .         .         .          | 02        .         .    g.65604
 ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAG | GATCGAAAATTAACAAAGTCT    c.780
 T  E  T  T  V  E  V  A  W  C  E  L  Q   | D  R  K  L  T  K  S      p.260

          .         .         .         .         .         .       g.65664
 GAGAGGCAGAGATTTAAAGAAGAAGCTGAAATGTTAAAAGGTCTTCAGCATCCCAATATT       c.840
 E  R  Q  R  F  K  E  E  A  E  M  L  K  G  L  Q  H  P  N  I         p.280

          .         .         .         .         .         .       g.65724
 GTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG       c.900
 V  R  F  Y  D  S  W  E  S  T  V  K  G  K  K  C  I  V  L  V         p.300

          .         .         .   | 03     .         .         .    g.79011
 ACTGAACTTATGACGTCTGGAACACTTAAAAC | GTATCTGAAAAGGTTTAAAGTGATGAAG    c.960
 T  E  L  M  T  S  G  T  L  K  T  |  Y  L  K  R  F  K  V  M  K      p.320

          .         .         .         .         .         .       g.79071
 ATCAAAGTTCTAAGAAGCTGGTGCCGTCAGATCCTTAAAGGTCTTCAGTTTCTTCATACT       c.1020
 I  K  V  L  R  S  W  C  R  Q  I  L  K  G  L  Q  F  L  H  T         p.340

          .         .         .         .         .         .       g.79131
 CGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT       c.1080
 R  T  P  P  I  I  H  R  D  L  K  C  D  N  I  F  I  T  G  P         p.360

          .         .         .         .         .         .       g.79191
 ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCC       c.1140
 T  G  S  V  K  I  G  D  L  G  L  A  T  L  K  R  A  S  F  A         p.380

          .    | 04    .         .         .         .         .    g.81991
 AAGAGTGTGATAG | GTACCCCAGAGTTCATGGCCCCTGAGATGTATGAGGAGAAATATGAT    c.1200
 K  S  V  I  G |   T  P  E  F  M  A  P  E  M  Y  E  E  K  Y  D      p.400

          .         .         .         .         .         .       g.82051
 GAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT       c.1260
 E  S  V  D  V  Y  A  F  G  M  C  M  L  E  M  A  T  S  E  Y         p.420

          .         .         .         .         .  | 05      .    g.109111
 CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGT | GGGGTGAAG    c.1320
 P  Y  S  E  C  Q  N  A  A  Q  I  Y  R  R  V  T  S   | G  V  K      p.440

          .         .         .         .         .         .       g.109171
 CCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATA       c.1380
 P  A  S  F  D  K  V  A  I  P  E  V  K  E  I  I  E  G  C  I         p.460

          .         . | 06       .         .         .         .    g.111226
 CGACAAAACAAAGATGAAAG | ATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA    c.1440
 R  Q  N  K  D  E  R  |  Y  S  I  K  D  L  L  N  H  A  F  F  Q      p.480

          .         .         .         .         .         .       g.111286
 GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATA       c.1500
 E  E  T  G  V  R  V  E  L  A  E  E  D  D  G  E  K  I  A  I         p.500

          .         .         .         .         .         .       g.111346
 AAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAA       c.1560
 K  L  W  L  R  I  E  D  I  K  K  L  K  G  K  Y  K  D  N  E         p.520

          .         .         .         .         .         .       g.111406
 GCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG       c.1620
 A  I  E  F  S  F  D  L  E  R  D  V  P  E  D  V  A  Q  E  M         p.540

  | 07       .         .         .         .         .         .    g.113014
  | GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGAC    c.1680
  | V  E  S  G  Y  V  C  E  G  D  H  K  T  M  A  K  A  I  K  D      p.560

          .         .         .         .         .         .       g.113074
 AGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAA       c.1740
 R  V  S  L  I  K  R  K  R  E  Q  R  Q  L  V  R  E  E  Q  E         p.580

          .         .         .         .         .         .       g.113134
 AAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG       c.1800
 K  K  K  Q  E  E  S  S  L  K  Q  Q  V  E  Q  S  S  A  S  Q         p.600

          .         .         .         .         .         .       g.113194
 ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCA       c.1860
 T  G  I  K  Q  L  P  S  A  S  T  G  I  P  T  A  S  T  T  S         p.620

          .         .         .         .         .         .       g.113254
 GCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTA       c.1920
 A  S  V  S  T  Q  V  E  P  E  E  P  E  A  D  Q  H  Q  Q  L         p.640

          .         .         .  | 08      .         .         .    g.114053
 CAGTACCAGCAACCCAGTATATCTGTGTTAT | CTGATGGGACGGTTGACAGTGGTCAGGGA    c.1980
 Q  Y  Q  Q  P  S  I  S  V  L  S |   D  G  T  V  D  S  G  Q  G      p.660

          .         .         .         .         .         .       g.114113
 TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAA       c.2040
 S  S  V  F  T  E  S  R  V  S  S  Q  Q  T  V  S  Y  G  S  Q         p.680

          .         .         .         .         .         .       g.114173
 CATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCA       c.2100
 H  E  Q  A  H  S  T  G  T  V  P  G  H  I  P  S  T  V  Q  A         p.700

          .         .         .          | 09        .         .    g.117072
 CAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTG | CCTCGTCGTGGCCGTAGCATG    c.2160
 Q  S  Q  P  H  G  V  Y  P  P  S  S  V   | P  R  R  G  R  S  M      p.720

          .         .         .         .         .         .       g.117132
 TCGGTTTGTGTTCCCATCTTTCTGCTGTTGCCTCTGTGTCCCGCATCTCTCCCAGTGCTC       c.2220
 S  V  C  V  P  I  F  L  L  L  P  L  C  P  A  S  L  P  V  L         p.740

          .         .         .         .         .         .       g.117192
 TTCCACCCCACCGCCAGTACTGTCTGCACCTCTTTCTCCTTCCCTCCTCCGGACTGCCCC       c.2280
 F  H  P  T  A  S  T  V  C  T  S  F  S  F  P  P  P  D  C  P         p.760

          .         .         .         .         .         .       g.117252
 GAGGAAACTTTTGCCGAAAAGCTTTCTAAAGCATTGGAGAGTGTCCTGCCTATGCACTCT       c.2340
 E  E  T  F  A  E  K  L  S  K  A  L  E  S  V  L  P  M  H  S         p.780

          .         .         .         .         .     | 10   .    g.119813
 GCCTCTCAGCGCAAGCACCGACGCTCCAGCCTGCCTTCCCTCTTTGTCAGTACT | CCTCAG    c.2400
 A  S  Q  R  K  H  R  R  S  S  L  P  S  L  F  V  S  T   | P  Q      p.800

          .         .         .         .         .         .       g.119873
 TCCATGGCGCATCCGTGTGGGGGGACCCCAACATACCCAGAATCACAGATATTTTTCCCA       c.2460
 S  M  A  H  P  C  G  G  T  P  T  Y  P  E  S  Q  I  F  F  P         p.820

          .         .         .         .         .         .       g.119933
 ACTATTCATGAACGTCCAGTTTCTTTTTCACCACCTCCCACCTGCCCACCGAAAGTAGCC       c.2520
 T  I  H  E  R  P  V  S  F  S  P  P  P  T  C  P  P  K  V  A         p.840

          .         .         .         .         .         .       g.119993
 ATTTCCCAGCGGCGTAAGAGCACCTCCTTCCTGGAAGCCCAAACTCACCACTTCCAACCC       c.2580
 I  S  Q  R  R  K  S  T  S  F  L  E  A  Q  T  H  H  F  Q  P         p.860

          .         .         .         .         .         .       g.120053
 CTGCTGAGGACTGTTGGCCAAAGTCTTCTTCCACCTGGTGGCAGCCCAACTAACTGGACA       c.2640
 L  L  R  T  V  G  Q  S  L  L  P  P  G  G  S  P  T  N  W  T         p.880

          .         .         .         .         .         .       g.120113
 CCAGAGGCCGTAGTTATGTTGGGTACTACAGCCAGTAGAGTAACTGGAGAGTCATGTGAG       c.2700
 P  E  A  V  V  M  L  G  T  T  A  S  R  V  T  G  E  S  C  E         p.900

          .         .         .         .         .         .       g.120173
 ATACAGGTCCATCCTATGTTTGAACCATCTCAAGTTTACAGTGACTATAGACCTGGACTA       c.2760
 I  Q  V  H  P  M  F  E  P  S  Q  V  Y  S  D  Y  R  P  G  L         p.920

          .         .         .         .         .         .       g.120233
 GTACTTCCAGAAGAAGCTCACTATTTTATTCCTCAGGAAGCAGTGTATGTAGCTGGGGTA       c.2820
 V  L  P  E  E  A  H  Y  F  I  P  Q  E  A  V  Y  V  A  G  V         p.940

          .         .         .         .         .         .       g.120293
 CATTACCAGGCCCGGGTGGCAGAACAGTATGAGGGCATTCCATACAACTCATCAGTACTG       c.2880
 H  Y  Q  A  R  V  A  E  Q  Y  E  G  I  P  Y  N  S  S  V  L         p.960

          .         .         .         .         .         .       g.120353
 TCAAGTCCTATGAAACAGATACCTGAACAGAAGCCAGTACAAGGGGGCCCTACTTCAAGT       c.2940
 S  S  P  M  K  Q  I  P  E  Q  K  P  V  Q  G  G  P  T  S  S         p.980

          .         .         .         .         .         .       g.120413
 TCTGTCTTTGAATTTCCATCTGGACAGGCTTTCCTGGTAGGACACCTTCAGAATCTAAGA       c.3000
 S  V  F  E  F  P  S  G  Q  A  F  L  V  G  H  L  Q  N  L  R         p.1000

          .         .         .         .         .         .       g.120473
 TTAGATTCTGGATTGGGTCCGGGATCTCCCCTCTCTAGTATTTCTGCACCTATCAGTACA       c.3060
 L  D  S  G  L  G  P  G  S  P  L  S  S  I  S  A  P  I  S  T         p.1020

          .         .         .         .         .         .       g.120533
 GATGCTACACGTTTGAAATTTCACCCTGTCTTTGTTCCTCATTCTGCGCCTGCTGTGTTA       c.3120
 D  A  T  R  L  K  F  H  P  V  F  V  P  H  S  A  P  A  V  L         p.1040

          .         .         .         .         .         .       g.120593
 ACTCATAACAATGAGAGCAGAAGCAACTGTGTATTTGAATTTCATGTTCACACACCAAGC       c.3180
 T  H  N  N  E  S  R  S  N  C  V  F  E  F  H  V  H  T  P  S         p.1060

          .         .         .         .         .         .       g.120653
 TCCTCTTCAGGAGAAGGAGGTGGAATTTTACCTCAGCGTGTTTACCGAAATCGGCAGGTT       c.3240
 S  S  S  G  E  G  G  G  I  L  P  Q  R  V  Y  R  N  R  Q  V         p.1080

          .         .         .         .         .         .       g.120713
 GCAGTGGACTTGAATCAAGAAGAACTGCCTCCTCAATCAGTTGGATTACATGGCTACTTG       c.3300
 A  V  D  L  N  Q  E  E  L  P  P  Q  S  V  G  L  H  G  Y  L         p.1100

          .         .         .         .         .         .       g.120773
 CAGCCTGTGACTGAAGAAAAGCATAATTACCATGCCCCAGAATTGACCGTTTCTGTGGTA       c.3360
 Q  P  V  T  E  E  K  H  N  Y  H  A  P  E  L  T  V  S  V  V         p.1120

          .         .         .         .         .         .       g.120833
 GAGCCTATCGGACAGAACTGGCCAATAGGAAGCCCAGAATATTCCAGTGATTCCTCACAA       c.3420
 E  P  I  G  Q  N  W  P  I  G  S  P  E  Y  S  S  D  S  S  Q         p.1140

          .         .         .         .         .         .       g.120893
 ATCACTTCTTCAGACCCCAGTGATTTTCAGTCACCTCCCCCTACAGGGGGAGCAGCTGCA       c.3480
 I  T  S  S  D  P  S  D  F  Q  S  P  P  P  T  G  G  A  A  A         p.1160

          .         .         .         .         .         .       g.120953
 CCTTTTGGCTCTGACGTCTCAATGCCCTTTATCCATCTGCCTCAGACAGTGTTACAAGAA       c.3540
 P  F  G  S  D  V  S  M  P  F  I  H  L  P  Q  T  V  L  Q  E         p.1180

          .         .         .         .         .         .       g.121013
 TCCCCACTTTTCTTCTGTTTCCCCCAAGGAACCACATCTCAGCAGGTCTTAACTGCCTCA       c.3600
 S  P  L  F  F  C  F  P  Q  G  T  T  S  Q  Q  V  L  T  A  S         p.1200

          .         .         .    | 11    .         .         .    g.123233
 TTTTCTTCAGGAGGATCTGCACTTCATCCACAG | GCACAGGGGCAGAGCCAGGGTCAGCCA    c.3660
 F  S  S  G  G  S  A  L  H  P  Q   | A  Q  G  Q  S  Q  G  Q  P      p.1220

          .         .         .         .         .        | 12.    g.130156
 TCCTCAAGTAGCTTAACAGGGGTTTCATCTTCCCAACCCATACAACATCCTCAGCAG | CAG    c.3720
 S  S  S  S  L  T  G  V  S  S  S  Q  P  I  Q  H  P  Q  Q   | Q      p.1240

          .         .         .         .         .         .       g.130216
 CAGGGAATACAGCAGACAGCCCCTCCTCAACAGACAGTGCAGTATTCACTTTCACAGACA       c.3780
 Q  G  I  Q  Q  T  A  P  P  Q  Q  T  V  Q  Y  S  L  S  Q  T         p.1260

          .         .         .         .         .         .       g.130276
 TCAACCTCCAGTGAGGCCACTACTGCACAGCCAGTGAGTCAGCCTCAAGCTCCACAAGTC       c.3840
 S  T  S  S  E  A  T  T  A  Q  P  V  S  Q  P  Q  A  P  Q  V         p.1280

          .         .        | 13.         .         .         .    g.133666
 TTGCCTCAAGTATCAGCTGGAAAACAG | AGTACTCAGGGAGTCTCTCAGGTTGCTCCTGCA    c.3900
 L  P  Q  V  S  A  G  K  Q   | S  T  Q  G  V  S  Q  V  A  P  A      p.1300

          .         .         .         .         .         .       g.133726
 GAGCCAGTTGCAGTAGCACAGACCCAAGCTACCCAGCCGACCACTTTGGCTTCCTCTGTA       c.3960
 E  P  V  A  V  A  Q  T  Q  A  T  Q  P  T  T  L  A  S  S  V         p.1320

       | 14  .         .         .         .         .         .    g.133907
 GACAG | TGCACATTCAGATGTTGCTTCAGGTATGAGTGATGGCAATGAGAACGTCCCATCT    c.4020
 D  S  |  A  H  S  D  V  A  S  G  M  S  D  G  N  E  N  V  P  S      p.1340

          .         .         .         .         .         .       g.133967
 TCCAGTGGAAGGCATGAAGGAAGAACTACAAAACGGCATTACCGAAAATCTGTAAGGAGT       c.4080
 S  S  G  R  H  E  G  R  T  T  K  R  H  Y  R  K  S  V  R  S         p.1360

          .         .         .         .         | 15         .    g.134896
 CGCTCTCGACATGAAAAAACTTCACGCCCAAAATTAAGAATTTTGAAT | GTTTCAAATAAA    c.4140
 R  S  R  H  E  K  T  S  R  P  K  L  R  I  L  N   | V  S  N  K      p.1380

          .         .         .         .         .         .       g.134956
 GGAGACCGAGTAGTAGAATGTCAATTAGAGACTCATAATAGGAAAATGGTTACATTCAAA       c.4200
 G  D  R  V  V  E  C  Q  L  E  T  H  N  R  K  M  V  T  F  K         p.1400

          .         .         .         .      | 16  .         .    g.135351
 TTTGACCTAGATGGTGACAACCCCGAGGAGATAGCAACAATTATG | GTGAACAATGACTTT    c.4260
 F  D  L  D  G  D  N  P  E  E  I  A  T  I  M   | V  N  N  D  F      p.1420

          .         .         .         .         .         .       g.135411
 ATTCTAGCAATAGAGAGAGAGTCGTTTGTGGATCAAGTGCGAGAAATTATTGAAAAAGCT       c.4320
 I  L  A  I  E  R  E  S  F  V  D  Q  V  R  E  I  I  E  K  A         p.1440

          .         .         .         .         .         .       g.135471
 GATGAAATGCTCAGTGAGGATGTCAGTGTGGAACCAGAGGGTGATCAGGGATTGGAGAGT       c.4380
 D  E  M  L  S  E  D  V  S  V  E  P  E  G  D  Q  G  L  E  S         p.1460

          .         .         .          | 17        .         .    g.135736
 CTACAAGGAAAGGATGACTATGGCTTTTCAGGTTCTCAG | AAATTGGAAGGAGAGTTCAAA    c.4440
 L  Q  G  K  D  D  Y  G  F  S  G  S  Q   | K  L  E  G  E  F  K      p.1480

          .         .         .        | 18.         .         .    g.136085
 CAACCAATTCCTGCGTCTTCCATGCCACAGCAAATAG | GCATTCCTACCAGTTCTTTAACT    c.4500
 Q  P  I  P  A  S  S  M  P  Q  Q  I  G |   I  P  T  S  S  L  T      p.1500

          .         .         .         .         .         .       g.136145
 CAAGTTGTTCATTCTGCGGGAAGGCGGTTTATAGTGAGTCCTGTGCCAGAAAGCCGATTA       c.4560
 Q  V  V  H  S  A  G  R  R  F  I  V  S  P  V  P  E  S  R  L         p.1520

          .         .         .         . | 19       .         .    g.136610
 CGAGAATCAAAAGTTTTCCCCAGTGAAATAACAGATACAG | TTGCTGCCTCTACAGCTCAG    c.4620
 R  E  S  K  V  F  P  S  E  I  T  D  T  V |   A  A  S  T  A  Q      p.1540

          .         .         .         .         .         .       g.136670
 AGCCCTGGAATGAACTTGTCTCACTCTGCATCATCCCTTAGTCTACAACAGGCCTTTTCT       c.4680
 S  P  G  M  N  L  S  H  S  A  S  S  L  S  L  Q  Q  A  F  S         p.1560

          .         .         .         .         .         .       g.136730
 GAACTTAGACGTGCCCAAATGACAGAAGGACCCAACACAGCACCTCCAAACTTTAGTCAT       c.4740
 E  L  R  R  A  Q  M  T  E  G  P  N  T  A  P  P  N  F  S  H         p.1580

          .         .         .         .         .         .       g.136790
 ACAGGACCAACATTTCCAGTAGTACCTCCTTTCTTAAGTAGCATTGCTGGAGTCCCAACC       c.4800
 T  G  P  T  F  P  V  V  P  P  F  L  S  S  I  A  G  V  P  T         p.1600

          .         .         .         .         .         .       g.136850
 ACAGCAGCAGCCACAGCACCAGTCCCTGCAACAAGCAGCCCTCCTAATGACATTTCCACA       c.4860
 T  A  A  A  T  A  P  V  P  A  T  S  S  P  P  N  D  I  S  T         p.1620

          .         .         .         .         .         .       g.136910
 TCAGTAATTCAGTCTGAGGTTACAGTGCCCACTGAAGAGGGGATTGCTGGAGTTGCCACC       c.4920
 S  V  I  Q  S  E  V  T  V  P  T  E  E  G  I  A  G  V  A  T         p.1640

          .         .         .         .         .         .       g.136970
 AGCACAGGTGTGGTAACTTCAGGTGGTCTCCCCATACCACCTGTGTCTGAATCACCAGTA       c.4980
 S  T  G  V  V  T  S  G  G  L  P  I  P  P  V  S  E  S  P  V         p.1660

          .         .         .         .         .         .       g.137030
 CTTTCCAGCGTAGTTTCAAGTATCACAATACCTGCAGTTGTCTCAATATCTACTACATCC       c.5040
 L  S  S  V  V  S  S  I  T  I  P  A  V  V  S  I  S  T  T  S         p.1680

          .         .         .         .         .         .       g.137090
 CCGTCACTTCAAGTCCCCACATCCACATCTGAGATCGTTGTTTCTAGTACAGCACTGTAT       c.5100
 P  S  L  Q  V  P  T  S  T  S  E  I  V  V  S  S  T  A  L  Y         p.1700

          .         .         .         .         .         .       g.137150
 CCTTCAGTAACAGTTTCAGCAACTTCAGCCTCTGCAGGGGGCAGTACTGCTACCCCAGGT       c.5160
 P  S  V  T  V  S  A  T  S  A  S  A  G  G  S  T  A  T  P  G         p.1720

          .         .         .         .         .         .       g.137210
 CCTAAGCCTCCAGCTGTAGTATCTCAGCAGGCAGCAGGCAGCACTACTGTGGGAGCCACA       c.5220
 P  K  P  P  A  V  V  S  Q  Q  A  A  G  S  T  T  V  G  A  T         p.1740

          .         .         .         .         .         .       g.137270
 TTAACATCAGTTTCTACCACCACTTCATTCCCAAGCACAGCTTCACAGCTGTGCATTCAG       c.5280
 L  T  S  V  S  T  T  T  S  F  P  S  T  A  S  Q  L  C  I  Q         p.1760

          .         .         .         .         .         .       g.137330
 CTTAGCAGCAGTACTTCTACTCCTACTTTAGCTGAAACCGTGGTAGTTAGCGCACACTCA       c.5340
 L  S  S  S  T  S  T  P  T  L  A  E  T  V  V  V  S  A  H  S         p.1780

          .         .         .         .         .         .       g.137390
 CTAGATAAGACATCTCATAGCAGTACAACTGGATTGGCTTTCTCCCTCTCTGCACCATCT       c.5400
 L  D  K  T  S  H  S  S  T  T  G  L  A  F  S  L  S  A  P  S         p.1800

          .         .         .         .         .         .       g.137450
 TCCTCTTCCTCTCCTGGAGCAGGAGTGTCTAGTTATATTTCTCAGCCTGGTGGGCTGCAT       c.5460
 S  S  S  S  P  G  A  G  V  S  S  Y  I  S  Q  P  G  G  L  H         p.1820

          .         .         .         .         .         .       g.137510
 CCTTTGGTCATTCCATCAGTGATAGCTTCTACTCCTATTCTTCCCCAAGCAGCAGGACCT       c.5520
 P  L  V  I  P  S  V  I  A  S  T  P  I  L  P  Q  A  A  G  P         p.1840

          .         .         .         .         .         .       g.137570
 ACTTCTACACCTTTATTACCCCAAGTACCTAGTATCCCACCCTTGGTACAGCCTGTTGCC       c.5580
 T  S  T  P  L  L  P  Q  V  P  S  I  P  P  L  V  Q  P  V  A         p.1860

          .         .         .         .         .         .       g.137630
 AATGTGCCTGCTGTACAGCAGACACTAATTCATAGTCAGCCTCAACCAGCTTTGCTTCCC       c.5640
 N  V  P  A  V  Q  Q  T  L  I  H  S  Q  P  Q  P  A  L  L  P         p.1880

          .         .         .         .         .         .       g.137690
 AACCAGCCCCATACTCATTGTCCTGAAGTAGATTCTGATACACAACCCAAAGCTCCTGGA       c.5700
 N  Q  P  H  T  H  C  P  E  V  D  S  D  T  Q  P  K  A  P  G         p.1900

          .         .         .         .         .         .       g.137750
 ATTGATGACATAAAGACTCTAGAAGAAAAGCTGCGGTCTCTGTTCAGTGAACACAGCTCA       c.5760
 I  D  D  I  K  T  L  E  E  K  L  R  S  L  F  S  E  H  S  S         p.1920

          .         .         .         .         .         .       g.137810
 TCTGGAGCTCAGCATGCCTCTGTCTCACTGGAGACCTCACTAGTCATAGAGAGCACTGTC       c.5820
 S  G  A  Q  H  A  S  V  S  L  E  T  S  L  V  I  E  S  T  V         p.1940

          .         .         .         .         .         .       g.137870
 ACACCAGGCATCCCAACTACTGCTGTTGCACCAAGCAAACTCCTGACTTCTACCACAAGT       c.5880
 T  P  G  I  P  T  T  A  V  A  P  S  K  L  L  T  S  T  T  S         p.1960

          .         .         .         .         .         .       g.137930
 ACTTGCTTACCACCAACCAATTTACCACTAGGAACAGTTGCTTTGCCAGTTACACCAGTG       c.5940
 T  C  L  P  P  T  N  L  P  L  G  T  V  A  L  P  V  T  P  V         p.1980

          .         .         .         .         .         .       g.137990
 GTCACACCTGGGCAAGTTTCTACCCCAGTCAGCACTACTACATCAGGAGTGAAACCTGGA       c.6000
 V  T  P  G  Q  V  S  T  P  V  S  T  T  T  S  G  V  K  P  G         p.2000

          .         .         .       | 20 .         .         .    g.139186
 ACTGCTCCCTCCAAGCCACCTCTAACTAAGGCTCCG | GTGCTGCCAGTGGGTACTGAACTT    c.6060
 T  A  P  S  K  P  P  L  T  K  A  P   | V  L  P  V  G  T  E  L      p.2020

          .         .         .         .         .         .       g.139246
 CCAGCAGGTACTCTACCCAGCGAGCAGCTGCCACCTTTTCCAGGACCTTCTCTAACCCAG       c.6120
 P  A  G  T  L  P  S  E  Q  L  P  P  F  P  G  P  S  L  T  Q         p.2040

  | 21       .         .         .         .         .         .    g.141141
  | TCCCAGCAACCTCTAGAGGATCTTGATGCTCAATTGAGAAGAACACTTAGTCCAGAGATG    c.6180
  | S  Q  Q  P  L  E  D  L  D  A  Q  L  R  R  T  L  S  P  E  M      p.2060

          .         .     | 22   .         .         .         .    g.142430
 ATCACAGTGACTTCTGCGGTTGGT | CCTGTGTCCATGGCGGCTCCAACAGCAATCACAGAA    c.6240
 I  T  V  T  S  A  V  G   | P  V  S  M  A  A  P  T  A  I  T  E      p.2080

          .         .      | 23  .         .         .         .    g.146538
 GCAGGAACACAGCCTCAGAAGGGTG | TTTCTCAAGTCAAAGAAGGCCCTGTCCTAGCAACT    c.6300
 A  G  T  Q  P  Q  K  G  V |   S  Q  V  K  E  G  P  V  L  A  T      p.2100

          .         .         .          | 24        .         .    g.148033
 AGTTCAGGAGCTGGTGTTTTTAAGATGGGACGATTTCAG | GTTTCTGTTGCAGCAGACGGT    c.6360
 S  S  G  A  G  V  F  K  M  G  R  F  Q   | V  S  V  A  A  D  G      p.2120

          .         .         .         .         .         .       g.148093
 GCCCAGAAAGAGGGTAAAAATAAGTCAGAAGATGCAAAGTCTGTTCATTTTGAATCCAGC       c.6420
 A  Q  K  E  G  K  N  K  S  E  D  A  K  S  V  H  F  E  S  S         p.2140

          .         .         .         .         .         .       g.148153
 ACCTCAGAGTCCTCAGTGCTATCAAGTAGTAGTCCAGAGAGTACCTTGGTGAAACCAGAG       c.6480
 T  S  E  S  S  V  L  S  S  S  S  P  E  S  T  L  V  K  P  E         p.2160

          .         .         .         .         .         .       g.148213
 CCGAATGGCATAACCATCCCTGGTATCTCTTCAGATGTGCCAGAGAGTGCCCACAAAACT       c.6540
 P  N  G  I  T  I  P  G  I  S  S  D  V  P  E  S  A  H  K  T         p.2180

          .         .         .         .         .         .       g.148273
 ACTGCCTCAGAGGCAAAGTCAGACACTGGGCAGCCTACCAAGGTTGGACGTTTTCAGGTG       c.6600
 T  A  S  E  A  K  S  D  T  G  Q  P  T  K  V  G  R  F  Q  V         p.2200

          .         .         .         .         .         .       g.148333
 ACAACTACAGCAAACAAAGTGGGTCGTTTCTCTGTATCAAAAACTGAGGACAAGATCACT       c.6660
 T  T  T  A  N  K  V  G  R  F  S  V  S  K  T  E  D  K  I  T         p.2220

          .         .         .         .         .         .       g.148393
 GACACAAAGAAAGAAGGACCAGTGGCATCTCCTCCTTTTATGGATTTGGAACAAGCTGTT       c.6720
 D  T  K  K  E  G  P  V  A  S  P  P  F  M  D  L  E  Q  A  V         p.2240

          .         .         .         .         .         .       g.148453
 CTTCCTGCTGTGATACCAAAGAAAGAGAAGCCTGAACTGTCAGAGCCTTCACATCTAAAT       c.6780
 L  P  A  V  I  P  K  K  E  K  P  E  L  S  E  P  S  H  L  N         p.2260

          .         .         .         .         .         .       g.148513
 GGGCCGTCTTCTGACCCGGAGGCCGCTTTTTTAAGTAGGGATGTGGATGATGGTTCCGGT       c.6840
 G  P  S  S  D  P  E  A  A  F  L  S  R  D  V  D  D  G  S  G         p.2280

          .         .         .         .         .         .       g.148573
 AGTCCACACTCGCCCCATCAGCTGAGCTCAAAGAGCCTTCCTAGCCAGAATCTAAGTCAA       c.6900
 S  P  H  S  P  H  Q  L  S  S  K  S  L  P  S  Q  N  L  S  Q         p.2300

          .         .         .         .         .         .       g.148633
 AGCCTTAGTAATTCATTTAACTCCTCTTACATGAGTAGCGACAATGAGTCAGATATCGAA       c.6960
 S  L  S  N  S  F  N  S  S  Y  M  S  S  D  N  E  S  D  I  E         p.2320

          .         .         .         .  | 25      .         .    g.149439
 GATGAAGACTTAAAGTTAGAGCTGCGACGACTACGAGATAA | ACATCTCAAAGAGATTCAG    c.7020
 D  E  D  L  K  L  E  L  R  R  L  R  D  K  |  H  L  K  E  I  Q      p.2340

          .         .         .         .         .         .       g.149499
 GACCTGCAGAGTCGCCAGAAGCATGAAATTGAATCTTTGTATACCAAACTGGGCAAGGTG       c.7080
 D  L  Q  S  R  Q  K  H  E  I  E  S  L  Y  T  K  L  G  K  V         p.2360

          .         .         .         .         .         .       g.149559
 CCCCCTGCTGTTATTATTCCCCCAGCTGCTCCCCTTTCAGGGAGAAGACGACGACCCACT       c.7140
 P  P  A  V  I  I  P  P  A  A  P  L  S  G  R  R  R  R  P  T         p.2380

          .         .         .         .         .         .       g.149619
 AAAAGCAAAGGCAGCAAATCTAGTCGAAGCAGTTCCTTGGGGAATAAAAGCCCCCAGCTT       c.7200
 K  S  K  G  S  K  S  S  R  S  S  S  L  G  N  K  S  P  Q  L         p.2400

      | 26   .         .         .         .         .         .    g.152473
 TCAG | GTAACCTGTCTGGTCAGAGTGCAGCTTCAGTCTTGCACCCCCAGCAGACCCTCCAC    c.7260
 S  G |   N  L  S  G  Q  S  A  A  S  V  L  H  P  Q  Q  T  L  H      p.2420

          .         .         .         .         .         .       g.152533
 CCTCCTGGCAACATCCCAGAGTCCGGGCAGAATCAGCTGTTACAGCCCCTTAAGCCATCT       c.7320
 P  P  G  N  I  P  E  S  G  Q  N  Q  L  L  Q  P  L  K  P  S         p.2440

          .         .         .         .         .         .       g.152593
 CCCTCCAGTGACAACCTCTATTCAGCCTTCACCAGTGATGGTGCCATTTCAGTACCAAGC       c.7380
 P  S  S  D  N  L  Y  S  A  F  T  S  D  G  A  I  S  V  P  S         p.2460

          .          | 27        .         .         .         .    g.159829
 CTTTCTGCTCCAGGTCAAG | GAACCAGCAGCACAAACACTGTTGGGGCAACAGTGAACAGC    c.7440
 L  S  A  P  G  Q  G |   T  S  S  T  N  T  V  G  A  T  V  N  S      p.2480

          .         .         .         .         .         .       g.159889
 CAAGCCGCCCAAGCTCAGCCTCCTGCCATGACGTCCAGCAGGAAGGGCACATTCACAGAT       c.7500
 Q  A  A  Q  A  Q  P  P  A  M  T  S  S  R  K  G  T  F  T  D         p.2500

          .         .         .         .         .         .       g.159949
 GACTTGCACAAGTTGGTAGACAATTGGGCCCGAGATGCCATGAATCTCTCAGGCAGGAGA       c.7560
 D  L  H  K  L  V  D  N  W  A  R  D  A  M  N  L  S  G  R  R         p.2520

          .         .        | 28.         .         .         .    g.160449
 GGAAGCAAAGGGCACATGAATTACGAG | GGCCCTGGAATGGCAAGGAAGTTCTCTGCACCT    c.7620
 G  S  K  G  H  M  N  Y  E   | G  P  G  M  A  R  K  F  S  A  P      p.2540

          .         .         .         .         .         .       g.160509
 GGGCAACTGTGCATCTCCATGACCTCGAACCTGGGTGGCTCTGCCCCCATCTCTGCAGCA       c.7680
 G  Q  L  C  I  S  M  T  S  N  L  G  G  S  A  P  I  S  A  A         p.2560

          .         .         .         .         .         .       g.160569
 TCAGCTACCTCTCTAGGTCACTTCACCAAGTCTATGTGCCCCCCACAGCAGTATGGCTTT       c.7740
 S  A  T  S  L  G  H  F  T  K  S  M  C  P  P  Q  Q  Y  G  F         p.2580

          .         .         .         .         .         .       g.160629
 CCAGCTACCCCATTTGGCGCTCAATGGAGTGGGACGGGTGGCCCAGCACCACAGCCACTT       c.7800
 P  A  T  P  F  G  A  Q  W  S  G  T  G  G  P  A  P  Q  P  L         p.2600

          .         .         .         .         .         .       g.160689
 GGCCAGTTCCAACCTGTGGGAACTGCCTCCTTGCAGAATTTCAACATCAGCAATTTGCAG       c.7860
 G  Q  F  Q  P  V  G  T  A  S  L  Q  N  F  N  I  S  N  L  Q         p.2620

          .         .         .         .                           g.160734
 AAATCCATCAGCAACCCCCCAGGCTCCAACCTGCGGACCACTTAG                      c.7905
 K  S  I  S  N  P  P  G  S  N  L  R  T  T  X                        p.2634

          .         .         .         .         .         .       g.160794
 acctagagacattaactgaatagatctgggggcaggagatggaatgctgagggggtgggt       c.*60

          .         .         .         .         .         .       g.160854
 gggggtgggaagtagcctatatactaactactagtgctgcatttaactggttatttcttg       c.*120

          .         .         .         .         .         .       g.160914
 ccagaggggaatgtttttaatactgcattgagccctcagaatggagagtctcccccgctc       c.*180

          .         .         .         .         .         .       g.160974
 cagttattggaatgggagaggaaggaaagaacagcttttttgtcaaggggcagcttcaga       c.*240

          .         .         .         .         .         .       g.161034
 ccatgctttcctgtttatctatactcagtaatgaggatgagggctaggaaagtcttgttc       c.*300

          .         .         .         .         .         .       g.161094
 ataaggaagctggagaactcaatgtaaaatcaaacccatctgtaatttcgagtgggtgga       c.*360

          .         .         .         .         .         .       g.161154
 gctcttgcttttggtacatgccctgaatccctcactccctcaagaatccgaaccacagga       c.*420

          .         .         .         .         .         .       g.161214
 caaaaaccacctactgggctctctcctaccctgccctcctcccttttttttacccctctc       c.*480

          .         .         .         .         .         .       g.161274
 ttttttattttttctttgctctttagaacccagtgaaaaataccagggtactggggtgca       c.*540

          .         .         .         .         .         .       g.161334
 actctttcttatgataggtcattagtgctttaagcaaaagatattagcagctttgactgc       c.*600

          .         .         .         .         .         .       g.161394
 agcattagcaattaggaaaaaaaaaaaattaagttccctgcggacatgtaactttgccat       c.*660

          .         .         .         .         .         .       g.161454
 cagttttgatgtggaaacactgtgatatataaaatgttgttggacaacagtagttttaag       c.*720

          .         .         .         .         .         .       g.161514
 agtaaaatatgaaacgtttaaaaagttccaaaaaaagctagctctgtcctttacttattg       c.*780

          .         .         .         .         .         .       g.161574
 agacactttaactttttcctttgtatttccattgtattagataaataaatgtgaatgtaa       c.*840

          .         .         .         .         .         .       g.161634
 aattgtataaattactgtacttgaatacttctgtttcccagtgttgcttgctggacattt       c.*900

          .         .         .         .         .         .       g.161694
 tagtgccttggacttctattgcttctgccattagcatcaacttaccagaccccagatcaa       c.*960

          .         .         .         .         .         .       g.161754
 taaagggcatgtggaaggaaatcgtaggtccatgtgaccccagcagtccagcagtggtta       c.*1020

          .         .         .         .         .         .       g.161814
 tgccaaagggaaattgaaaaagtatttttttaagtcattcaacaactttgtctagagcag       c.*1080

          .         .         .         .         .         .       g.161874
 gtgtaagatgagtagggtgggaagttaggttggcatcagtggttaaaaacagaaagttct       c.*1140

          .         .         .         .         .         .       g.161934
 gtttcgggaatagtgaggagggggtgttgtaacaaaattggacaacttaaaagaatggtg       c.*1200

          .         .         .         .         .         .       g.161994
 tgtgctgggtgaaagacaaagactaaagaatgaggaaacaaacgtgatgcctggccagtg       c.*1260

          .         .         .         .         .         .       g.162054
 actgtcatataaacctttcttatttgagctaggcttgaacagacgtgacctagaagaaac       c.*1320

          .         .         .         .         .         .       g.162114
 tgaacataaagagaagggggtggggggctagttttcaagttggggaacctgatagtgaaa       c.*1380

          .         .         .         .         .         .       g.162174
 agtcacagatggagaaaattgctctcagaaaaactgtttggattgctttcctcttgttgc       c.*1440

          .         .         .         .         .         .       g.162234
 acatgtaccatgcatttctcagcttggggtactacattttgtggaaagttaatctatcta       c.*1500

          .         .         .         .         .         .       g.162294
 tctttccacatctgaattaatcattctaggaaagaatacttattcctactcatttccttt       c.*1560

          .         .         .         .         .         .       g.162354
 atgatgtccaaatggttgcaggatcataatctattgtgccacctttatttctagaagtac       c.*1620

          .         .         .         .         .         .       g.162414
 aactaatatgttcacattttcaaataaataatactccccgtaagtaataactgcaaccaa       c.*1680

          .         .         .         .         .         .       g.162474
 tcagtgttattcagtgctatgcctccttgtaatgggtagttattaattattttcagagct       c.*1740

          .         .         .         .         .         .       g.162534
 ttccggaaatactgtcctaactggctatgtttaggatctttgttatctctgaagacaaag       c.*1800

          .         .         .         .         .         .       g.162594
 aaagaagctaggactcttaattttggggtgcttcttgactcttagttgggaaactgaaaa       c.*1860

          .         .         .         .         .         .       g.162654
 tatttccaaccttttacccacgtcaatggcatattctgggaatcaccaccaccaccacca       c.*1920

          .         .         .         .         .         .       g.162714
 ctaccacagaaagaggctggaggctcctgtaccctgttcattccttaagggccctgcttc       c.*1980

          .         .         .         .         .         .       g.162774
 ccttagtaagtaagtaagttggtctacggccctaaatatgcaaatgagagctgaaggttt       c.*2040

          .         .         .         .         .         .       g.162834
 ttaaaaggtagaaaggaaaagggcaagggcttccacccctgctttaaaatgatttattta       c.*2100

          .         .         .         .         .         .       g.162894
 ttctctgcttgtatttcttgtggagagagtaaggatagaaccaacaaggggctgagtagc       c.*2160

          .         .         .         .         .         .       g.162954
 tgagaaaggggccacccaagagtgaaacatactttataccagaggagcagtggagcctca       c.*2220

          .         .         .         .         .         .       g.163014
 tgcagcacattatcatttgttatttgggtttaataataattttgacatcttttcactcat       c.*2280

          .         .         .         .         .         .       g.163074
 acacaaaaaaagtcagaactggtgttatttactgttgatttcatcctcctgtgtatgaaa       c.*2340

          .         .         .         .         .         .       g.163134
 taacaagcctagaggaatgaactagtgctactgaactgtttaaattatttttgtgttaat       c.*2400

          .         .         .         .         .         .       g.163194
 agtacactttgagtatctttttccacattaaaaactttctgaattataaatgttttcctt       c.*2460

          .         .         .         .         .         .       g.163254
 acattatttaacaatgtacactgttaaaaataaaaataaaaattcaaactttgggggttt       c.*2520

          .         .         .         .         .         .       g.163314
 ctcagcagccgttaattgtacattttgcactaactctgggtgttgcgcttcttgtaagat       c.*2580

          .         .         .         .         .         .       g.163374
 tgcgctttgtgcttcagtttgttacctttgtagacttatttaatgaaaccattcaaataa       c.*2640

          .         .                                               g.163394
 accaaacttgcttttgttga                                               c.*2660

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The WNK lysine deficient protein kinase 1 protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift mutations, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.

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