LOCUS       NG_033244              36756 bp    DNA     linear   PRI 21-MAY-2013
DEFINITION  Homo sapiens transmembrane protein 5 (TMEM5), RefSeqGene on
            chromosome 12.
ACCESSION   NG_033244
VERSION     NG_033244.1  GI:506328111
KEYWORDS    RefSeq; RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 36756)
  AUTHORS   Vuillaumier-Barrot,S., Bouchet-Seraphin,C., Chelbi,M., Devisme,L.,
            Quentin,S., Gazal,S., Laquerriere,A., Fallet-Bianco,C., Loget,P.,
            Odent,S., Carles,D., Bazin,A., Aziza,J., Clemenson,A., Guimiot,F.,
            Bonniere,M., Monnot,S., Bole-Feysot,C., Bernard,J.P., Loeuillet,L.,
            Gonzales,M., Socha,K., Grandchamp,B., Attie-Bitach,T.,
            Encha-Razavi,F. and Seta,N.
  TITLE     Identification of mutations in TMEM5 and ISPD as a cause of severe
            cobblestone lissencephaly
  JOURNAL   Am. J. Hum. Genet. 91 (6), 1135-1143 (2012)
   PUBMED   23217329
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC084357.23.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a type II transmembrane protein that is
            thought to have glycosyltransferase function. Mutations in this
            gene result in cobblestone lissencephaly. Alternative splicing
            results in multiple transcript variants encoding different
            isoforms. [provided by RefSeq, May 2013].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36756             AC084357.23        46848-83603         c
FEATURES             Location/Qualifiers
     source          1..36756
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q14.2"
     gene            5001..34756
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /note="transmembrane protein 5"
                     /db_xref="GeneID:10329"
                     /db_xref="HGNC:13530"
                     /db_xref="MIM:605862"
     mRNA            join(5001..5327,6217..6372,10168..10270,27289..27603,
                     30432..30602,33873..34756)
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /product="transmembrane protein 5, transcript variant 1"
                     /transcript_id="NM_014254.2"
                     /db_xref="GI:503774416"
                     /db_xref="GeneID:10329"
                     /db_xref="HGNC:13530"
                     /db_xref="MIM:605862"
     exon            5001..5327
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=1a
     CDS             join(5159..5327,6217..6372,10168..10270,27289..27603,
                     30432..30602,33873..34290)
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /note="isoform 1 is encoded by transcript variant 1; type
                     II membrane protein"
                     /codon_start=1
                     /product="transmembrane protein 5 isoform 1"
                     /protein_id="NP_055069.1"
                     /db_xref="GI:7657178"
                     /db_xref="CCDS:CCDS8966.1"
                     /db_xref="GeneID:10329"
                     /db_xref="HGNC:13530"
                     /db_xref="MIM:605862"
                     /translation="MRLTRKRLCSFLIALYCLFSLYAAYHVFFGRRRQAPAGSPRGLR
                     KGAAPARERRGREQSTLESEEWNPWEGDEKNEQQHRFKTSLQILDKSTKGKTDLSVQI
                     WGKAAIGLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVN
                     NVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRN
                     GGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTI
                     YENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGV
                     NTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKEL
                     PAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS"
     exon            5324..5660
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=1b
     exon            6217..6372
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     exon            10168..10270
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            27289..27603
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            30432..30602
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            33873..34756
                     /gene="TMEM5"
                     /gene_synonym="HP10481; MDDGA10"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
ORIGIN      
        1 ggctgaggca ggacaatcac ttgaacctgg gaggcacaga ttgcattgag ctgagactgc
       61 accactgcac tcctgcctag atgacagagc aagactctgt ccaaaaaaat aaaaaataaa
      121 aataagaaaa aataaaaata tgtatacaaa taaaatagac tagccaaaaa ttggaagaat
      181 atacttaatg tacataaaca aatgattgct gtataaagta aatagaaatt ctacaatcaa
      241 tagtaaaaga taagcaacaa ataaaaaact atacaaaaca taaaaactga ggataaaaac
      301 aaaaaaacaa taaatatatt aaaagatact caacctcatt attaaccagg gaaatgaaaa
      361 ttacaataat aaaagtccat tgcagccatc atattggtaa aaattttaag gactgatcta
      421 acaaaatgtt tactacttgg tcattaaaat atcacataca ctctctccta taatctctac
      481 tggatcaaat aaaaaatcta aatagcaaag agtaaaaata ttgcactttc aggatgcagt
      541 ggtaaattaa tcagtttcta tgatttcatt attaagaaga aatgataaaa tgttaaacca
      601 actgtccaat taataaagtt agagaaaaga tcaaacaaac aggaaaacag aaaaaacaaa
      661 ataatgaaaa ataatgcaca atctagtaac tgccacatag acaaacaaaa ctgataaatc
      721 caaagatagt tggaaggaga ggggaaaacc aataataaaa tcatacaatc aattataaaa
      781 gctgaaaatt tcactataaa aaagaaaaac tcaaaagaat aaaattagga atgaaagaag
      841 ggatatatct gaatgctttt taatcctaat gaggtaaact ggcttcttag taaataaaaa
      901 ttgccaaaac agacttaagt attaatatta caagcaagaa taaaccaaac gagtgttatt
      961 aaagaactat ctcaaaaaat agttctaggg ccaatgaata ttactgaaaa gtgcagtcag
     1021 acttttacag acagtatttt ccatgctata taaactgttc aaggactgaa atgctatcca
     1081 acccatttga gacagctagc aataatcctg atataaaata aacatggcag agtttgtaaa
     1141 aataaagata aatctcagat tattaaaggt gcattattaa tcagatgtgt ctattctact
     1201 ggaaaagaat aaatctatct gggtgagtta agtgagttaa tagaaataag aatgcatgaa
     1261 gttgatggat tcacgggaat atgtataagc catcaagacc ttgtgatgaa aagtcaaaat
     1321 taggagaggg aatacatcaa atatttacat tcttgcaacc acaaaaaatg aagtgagcaa
     1381 aaagcacaga aagacatcac taaatgagac taaaagaggt tgaaagggca ataacaaatg
     1441 ctggagaaga tatggagaaa agggaaccct tgtacactgt tggtggaaat gtaaattagt
     1501 accaccacta tggagaacag tttggaggtt cctcaaaaaa ttaaaaatag agctaccatg
     1561 ggagtcagca atcccactcc taggtatata ctcaaaagaa aggaaatcag tatattgaag
     1621 agatatctgc actcccatgt ttattgcaac actattcaca atagccaaga tttggaagca
     1681 acctaaatgt tcatcaacag atgaatggat aaagaaaatg tggtacatat acaccacaga
     1741 gtgctatcca gccataaaaa aagaatgaga gcttgcattt tgcaacaaca tggatgaaaa
     1801 tgaaggtcat tatgttaagt aaagtaagcc aagtacagaa agaccaactt tgcatgttct
     1861 cacttatttg tgggagctgc aaattaaagc aattgagacc aggcacagtg gctcacgcct
     1921 gtaatcccag cactttgaaa ggccaaggca agctgatcag ttgagcccag gatctcaaga
     1981 cccacctggg caacataatg agagcctgtc tctactttaa aaaataaata aataaaacaa
     2041 ttgaactcat ggagatagaa agtagaagga tggctactaa aagctgtgaa gagtagtggg
     2101 ggcaggtggg ggaggagagt ggggatggtt aatgcagaca aaaaacagta agaaagaatg
     2161 aataagacct agtctttgct agcacaacag ggtgactata gtcaaaaata atttaattgt
     2221 acattttaaa ataactaaaa gagtataatt gcattgtttg taacacgaag gatgaatgct
     2281 tcagtggatg tatgctctat ttactctgat gggattatta cacattgcat gcctatatca
     2341 aaataatctc atgtaaccca taaatatata cacctacgat gtactcacaa aatttttttt
     2401 taatttttaa gaggttgaaa tgcatttata tcactcctgg ggcctttcag tagcctccta
     2461 ccccaagttg atgataataa tatcattaga aaaacagcat atgcaaatga agtcagtggt
     2521 aaatgagaga tggagtcaca tgggttcaag ctgtcttgaa tcactctctg agactatcac
     2581 catggtggca cccactcata agggctttta gtagaacaga gtccatagac aactatcaca
     2641 ctagttaagg ctggtggatc atatggaata cataaacaaa attggtgatg aaatgttaca
     2701 ccaatgatga aactgtgcat agggtttaga gggtgtgggg aaggggaaat aggagaggga
     2761 aagatttaca gaggaagtga tgtttgcaca gaatctgttt ctgctcatct gcttcaattt
     2821 cacctcagag ttgttctgtc tttaaccttc atcctagttt ctgtttggtt ggttattagt
     2881 atgttgtttg attgattgtt taaagaaggc gttataattt gcttactatt tcccaatgcc
     2941 aatatatttc tgtagagttt tattacttat ttttgtgagc attgtactca catgaaaaag
     3001 aaaaatgtat cttcttagga ctgattctta caaatttgaa atagctatag tttataactt
     3061 acatggccaa gccctgctag aagtatcttg caaagggttt gacacagaag cttggccaag
     3121 ctgtgaaaaa tctctcaaag tagttaacac acttcttgag tattactgga aacttgataa
     3181 actaagaaga gaattttgac caggtatcac aagaaatttg tactggggac ttctaagaat
     3241 aagcgtgtac tatttcacag tcaactagaa gaaggcatta ggacattagg gctattttct
     3301 caatatcttg ttgattaata gttcttccct ttgcagacag agtagaaaat ttcaccaagt
     3361 aaagatttta gccctgcttt agtttaattc atctcatatt cctttatttc tattcttcct
     3421 cccacatctt tccttctcag gtctggttcc ctatatgcgg agcttcaacc cccagaggat
     3481 atttaacctt gtctccccct ccacactgct gcattcccca ccacatctct ttccctctct
     3541 ttccatccac ctgaagagat gagagcatat acagaaagta gctcccagct gtagctcaac
     3601 cattaaacac caagagaaag gaaaatgaac tctgccagac ttagatcaat tagaagattc
     3661 ctttgtaacc taaatacatt tttaaaagct tatcatcaaa ttatgcagtc atttgcagtt
     3721 tgaggtaaaa caactccttc attttcatgg ccctctcccc tattcaagat gacatcaact
     3781 gcatattagt tttaccttgt atgcatttct caatagtaaa accattagtc agtagcatct
     3841 gaatgtacat tgatacagtg ggtgttttgt ggtaattata aggtaattac ttcctatcct
     3901 taaataattg tcatttccac aaacaaacaa aataggataa acaacaatac agcatacata
     3961 aaacaactgc catctcccta agacaccaga atagcctgtt aatcaaggaa agctaaattt
     4021 attaaatcta ctacagtaag ggaggccaca ctttgacaga agcttggcag tctcagaagg
     4081 agaaggttgg gggtgatatt tataggattt ggggagtctg agcaaaaatg gtttaaaaca
     4141 ggtcttttga ggcagggaac tgtttggggg attgggtaaa gtgtttgacc taatagttta
     4201 gggtcggtgc tagagtgacc aattttactg atttcctagg actttctcaa ttttagcact
     4261 aaaaatcctc caactggaga atccttacag tcctgggcaa actgggacca ttggtcaccc
     4321 taattagcag acataccgtc gcaagactgc tgggtaattt gaacagtagt accagagcaa
     4381 ctgacaaaac attgtagccc atcttcccaa ggctggatac aaagttttct gaagcattca
     4441 catttacagc ctctatttga caaaatactg catgcctatg tgcgttcaac tcacataata
     4501 atgaaactta actttaaaaa tgtttttatt gcagtaaggt atataaaaca tgaattcgac
     4561 agtttaacta tttctatgca tacaagtgag tggtattaat tacattcaca atgttaagcg
     4621 accatcatca cttaattttt ttaaaggacg tttatattca ctcatctatc aacgtagtag
     4681 gcactgtcct aggcgctagg gattccatgc agagcaaaaa acgtcacagt ccatgccttc
     4741 acatggcctt catggaccac cgcgggtgtt ctttttcccc cgagtcttta tgtacttggg
     4801 aaaagtggcc agggttgaaa ggtgcaatga gtacacggca gaggtcagag aggttcccac
     4861 tcagcccggc gtctggaagc agcgtggggt aggggccgct ccagtacccc ctcctccagt
     4921 gtcgaaggtg ggcaggccct cggccgggtg gatgagccgc gactggaggg ggcggggcct
     4981 gggcgggagg cgggcggtgg gcgtgtccgg ggcggggctg taccgggcgc tgggcggagg
     5041 agccttggct ggggactgcc tggaaacggg ctgggcctgc ctcggacgcc gccggtgtcg
     5101 cggattctct ttccgcccgc tccatggcgg tggatgcctg actggaagcc cgagtgggat
     5161 gcggctgacg cggaagcggc tctgctcgtt tcttatcgcc ctgtactgcc tattctccct
     5221 ctacgctgcc taccacgtct tcttcgggcg ccgccgccag gcgccggccg ggtccccgcg
     5281 gggcctcagg aagggggcgg cccccgcgcg ggagagacgc ggccgaggta ggactgggtc
     5341 ggcggcttcc ttccggctct gcgctcctgg ctggggctgc tgggcggctg gggccgggtc
     5401 cccgcacccg gctctcaagt ccgggattac ccgcagggcc tgagaagcgc tttgccccct
     5461 acagcctctc gagccagccc ttggctcgga attggagaat ggtcctcatt cttacccaga
     5521 tctcacacgc cgtccccgct cccgatccca gggggtgaca ggcgcgcacg cctttcaaac
     5581 acgtgttaaa atccaagacg tcgtctcaaa tgccagagat ttgcgggaat gctcctggaa
     5641 ggcctcaaaa tcgccgcaag gtttaagaca tccgtttcca tgttgaaaca aagccctctc
     5701 taatcctgca gtgaccataa ggcagacttt acctccaaat tctggtcccc tgtcctgtgt
     5761 tttaacttgt gttaagatca gactcggctt tctctttccc tttattcaga attttgcacg
     5821 atagtatcta agactggtga acactacact ctgaagtcag ttttttgtgc ataggttacc
     5881 tgtatacaat ggataaaaat aattgcaaaa gttaagcttg taacttgata catattatcc
     5941 tgttattttt aaaggttttg tgttggggaa gagaattttc ctgtctcaag gtagcatttt
     6001 atttctaaga cttttcagag taaaaaaagt tcagtaaaaa aattgctgat tttctttttt
     6061 gttttcattg tgtattacca gtttaaattc agttgctgta cctctcagaa attaaagtta
     6121 ggatgaaatt agaactaaca cttaatttaa atgatttgaa tttacctaca actgcaataa
     6181 taccttactg gtaaacactt actcttttta aaacagaaca gtccactttg gaaagtgaag
     6241 aatggaatcc ttgggaagga gatgaaaaaa atgagcaaca acacagattt aaaactagcc
     6301 ttcaaatatt agataaatcc acgaaaggaa aaacagatct cagtgtacaa atctggggca
     6361 aagctgccat tggtaagtta atacgtagaa ggaagacatg taaaaagcat tataaaatgt
     6421 attttattga tatgaaattc attttaatat aatttatttc ataatttgtt aattaaggca
     6481 tcatgatata ttttttcgct ttttgtcaat aattcctttc tccttccaat tagacaacat
     6541 ctgtttgtaa atgtacacac atacatattc cactgttggt ctttagcaga gcacagcttc
     6601 atttattgat acattgagta ggctgtatag tgtcattaga ttgcaatgca tatgtcaact
     6661 gaattttcat gaatctgtgt attttttgga cacttgatac acaagtataa gatgtggccc
     6721 ctgcccttga tggccaaaca catttgggaa acactgaaga gtacaaagtt aaacaaggtt
     6781 cttcattgca ggcctttctc aagagccttt aatatgacaa tgttcattgt atcagcgaag
     6841 gaatatatta tagtatgtag ttgattaaac ttgattgacc acagaagcat ttttgctgtg
     6901 aatatcatga gagtgtagtg ttctaagata tatattatgc tcaattagag aatggggccc
     6961 tgagggttta aagagtcaca aagaatttag tgacttagaa agcgctttat gtggcctttg
     7021 aacatgagtt gggtttatgt acaataaggc atatggatag aaagtaccag atgagaggaa
     7081 aatgtacaga gcatagtgct ctgctcatgg tatttcataa attcgttcat acttacatac
     7141 aagtatatat cctagaagat tactaccaac ctctaaattt caagtacctg aaaccaggcc
     7201 ttcaatcatc aagttctagc cattattttt taaataaagt ctctaatatt gatttcttct
     7261 tttaaatctc agattttcat ttccagactt ctctcttttc aatctgataa gtgcaaagtg
     7321 gccaagtgaa tttcatcaaa tgctaccttt tttttttaac acctctgcta gcaggaaaaa
     7381 tgctactttg atcagcctat tctctagaca cagttataaa ataccgttat agaaattccc
     7441 attcaaaagg ggagaaaaat tgaagtaaaa aagtgtcact ggtccaagca attttgaaat
     7501 ctaaatttca tctaaatggc cagctccatt agatgatatt gcaggcctag gaataatcta
     7561 taggttgtac agctttgccc tctggcatct cagccacact cttgaagtca tcttttcctt
     7621 tttcataaaa agtagcacaa gtttgcagct tcgtaatttt atcagcctgt tgacagctgg
     7681 taaaattttc agagcccatc agccttcttt cattgtgacc tcttgctgtc ttttttagtc
     7741 caagctggca gcgtttctgc tcataaaaca ttctgaagaa ccttgtgggc cctctgtgta
     7801 tgtcacagga ttcactccat tagatgggaa gctcctctgc agatcttttc tgagtaatcc
     7861 catctccatt tctggcttct gctgagatgg ctgaggagac ctgtaagtca catgtataat
     7921 ctcttcaaag agccctttgt gtgaatgaat attcagatct tctgatcctt ctgaggcact
     7981 agcaaaaggt tgtgcagcca catccttggt cttgtttctg gaacaccctt ttcaggcagc
     8041 aaatctaatt tttcacatct tttgcaatct taatggtccg agaatttccc aaatcatcaa
     8101 attctggttc ccttttgctt aacagttttt ccttctatct cttttttctt atatttcact
     8161 aatcaccaag aaaccagtcc acacctttca ctttgcttgg aaccctccag ctaattatta
     8221 aagtttatca caagttctgc tttccatgta actgcaggat acaatccaac taagcttttt
     8281 actgttatat aacaaggatc ctcatccttc cagtttctaa taacacattc ctgattttct
     8341 tctgagccct caccagcaat ttctttaata cgcatattct aggcatggcg tctcacgccc
     8401 gtaatcccag cactttggga ggctgaggcc ggtggatcac ttgaggccag gagttcaaga
     8461 ccagcctggc catcatggtg aaaccccgtc tgtaccaaaa atacaaaaat tagccagaca
     8521 ttgtggcacg tgcctgtaat cccagctact caggaggctg aggcaggaga attgcttgaa
     8581 cccgggaggt ggaggttgca gtgagccgag atcatgccac cttactccag cctgggcgac
     8641 agagcgagac tctgtctcaa aaaaaaaaaa cattgcatat tcttaccaac aatctgcttg
     8701 tgatcattta gatatcctct aagacaatac aggttttctc tactctacct cactttcttg
     8761 agtcttcact agctgagtca ttaacatcca tatttctatc tgcaggttat tcaaggcaat
     8821 ctaatctagg ctttttaaaa tcatgtcctc acagttctct cagcctttcc ccattaccca
     8881 atttcagaga cacttccaca tttttaagta tttgttacag tagcacctca tttccaggta
     8941 ccataatctt aactgtataa tccatagcat cctattgcag ccataacaaa ttaccacaaa
     9001 tgcagtatcc tacctttctg aaggcagaac tctaaaatgt gtggggtctg tgttactttt
     9061 tgaggctcta gaggagaacc tgtttcctta ccgtttagag tttctagcgg ctacccgtat
     9121 tccttcattt atggccccac atcactctga cctctgcttc tatctttata tatcccttgc
     9181 ctcactctga cactcctgcc tcccttgtgt gaggactctt gagattacat agggcccacc
     9241 tagataatct ataataatct cttcacctca gcatccttaa cttaatcata tttttaaagt
     9301 gtcttttgcc atgtaaggta acatattcat agattctaaa gattagaata tggacatctt
     9361 tgctggtggg gcagagggac attattcaac ccatcacatt tggaaagcgt tatctaattg
     9421 gccacatttt aaacgtggtg gcttgcgttt cctttagtac cagggtacaa tgagaatgga
     9481 acaaaaacct ctttgagtgt aaccaaaaca gggtgcccag aggtggtgta tggtctccat
     9541 agtgcctcat tgagtaacac tgctctcctc tactctcaga gctttcattc aggtgaaatc
     9601 atgataaaac atcaggggct gccataagga gaaaagatgc aatgacattt gtctgtgagg
     9661 ggatcatgca ttcagggata tgtgttcaag tgaggaggag gtaatatccc cttgacatat
     9721 tgaatgtatt aatatatgta catacatgag ctcctctggc tccatttggc acaaaatggc
     9781 aactccccca atctgttata aaagcagttc taaccacata gtatagttta ctttgtaata
     9841 taatacattt catttcagaa taagacaggt ggtaaagatc catataaatt aggggtttct
     9901 caaatctaga gtaggagagg tctttaatat taactcacat tttgccacat tttacacact
     9961 aacagcttct gagctctgtc tctcattagc tgccatgttg atgatttgga gctgttgctt
    10021 gatagcactg cctgccaacg gcccaaagga gaggcattct ggttttatag tcaaatgagt
    10081 aaaagaacag aacgtaaact tgtctcatgc actaaagtag atgagacagt aaattgtttt
    10141 gattttgttt ttgttgttaa ttaccaggct tgtatctctg ggagcatatt tttgaaggct
    10201 tacttgatcc cagcgatgtg actgctcaat ggagagaagg aaagtcaatc gtaggaagaa
    10261 cacagtacag gtattggttg tattagttgt gcaacattaa cctttgatgt tttgctctgc
    10321 aatattttct gtaaatacta aaagaaaaat aataggaaaa tatatttata aaaatacttc
    10381 tatttcaact tgtaaagaat agagaagtaa atctcatgaa tatgtattca taattaagct
    10441 tacttggacc ttatgaaatt gtatattaca gaatactcct ttttggcatc atatgtctgt
    10501 tttattttta cctaattata tagaaaagtt catactccac atcttacagc gtttgaatgg
    10561 tgacagccat tgaaaacatt ctgtatcttg gaggaataat atgtaaacct aaaagtattt
    10621 tcatttttct ctttcatgta atagtcatgt tcacttttta aaatatttag gtgatatcaa
    10681 agctcttgct gtcactttgt agatttttgt ttattaaaac aaatttgatg agttctatca
    10741 ggatttattt tttattttag atttaataaa gccaatgtat tgcttagact tttttggcct
    10801 ttttatataa ctcttttcta tgactgcata ttttctgagt gtttttaagt atattaggat
    10861 tattttattt aggaaaacta taattttatc atatgaaatg ctattttatt agattttgct
    10921 ttattgaaat taaaaataaa aacattattt ttaaatgctt attttatata acagttgtat
    10981 tattggggga aaatgtgaac taaagattct gctttgtatt ggaatttcag tcttttctac
    11041 agaaatcagg aaaggaaaag ctatagttaa cctcaatttt gttctaattt ttactacagc
    11101 tttaattctt tatttacttt atatacactt ggaaagcagt tttattgcat gtatcttttc
    11161 aaagttaaaa agtaaacagg tttttaaaat tatcattggt aatgattatt tttcctttca
    11221 tcttcatgct tctgttgatc taatcccatt caagagctta aatagactta caatggttgg
    11281 atttgggtgt gtgaaagtaa atgtgtatta tgtgtataaa tctaatattt tggtatttga
    11341 aaagtaaatg tgtgttagga atattagtct aatccataat atataaaatt ttcagaaaag
    11401 ttattaaaaa ttcataaagt tagcatcttt aaggttaaaa ttatacattg ttactataat
    11461 aatagtgaaa gatttgagca aagaacatta actcccaaaa gaaagccaaa tgtatccttt
    11521 acttctgaaa tatttgtggg agattttaca ggcatcctct agagatactg cgtgttcagt
    11581 tccacaccac tgcagtcaag caaatactgc aataaagcaa gtcatatgaa tttttttatt
    11641 atccagtaca tatgaaagtt atgtttacac tgtactacag tctattaagt gtgtaatagt
    11701 attatgccta aaaaaaaaaa atacgtacct taagtgaaaa atactttatt gctaaaaaat
    11761 gctaacagtt atctgaccca tcagcaagtc atctttttgc tggtggaggg tcttgcctcg
    11821 atgttgatgt ctaatcagtg tattgatgac taatcagggt ggtggttgct gaaggctggg
    11881 gtggctgtga caatttctta aaataagaca acaatgaagt ttgccacatc agttgactct
    11941 tccttcacaa aagttttctc tgtagcacat gatgctattt ggtggcattt ttacccatag
    12001 aacttctttc aaaattggag tcaatcctag gccggatgca gtggctcatg cctgtaatcc
    12061 cagtactttg ggaggctgag gtagctggat cacttgaggt caggagttcg agaccaacct
    12121 ggctatcatc gtgaaacccc gtctctacta aagatacaaa aattggctgc aagtggcagc
    12181 acacacctgt aatcccagct acttgggagg ctgaggcaaa agaatccttg aacctgggag
    12241 tcagaggatg cagtgaggta agatcatgcc actgccctcc aaccccgggc gacagaatga
    12301 gtcaaagaaa aaaaaaaatt ggagccagtc ctctcaaacc ctactgctgc tttatcaact
    12361 acatttttgg aatattctga atcctttatt gtcacttcac caatgttcac aacattgtat
    12421 cttcaccaga agtagattcc atctcaggaa accactttct ctgctcattc ataaaaagca
    12481 actcctcatc tgttgaagtt ttatcatgag attgaagcaa ttcagtcaca ccttcaggtt
    12541 ccacttctaa ttctactttt ctttccattt ctaccacatc ttcagtgact tcctccactt
    12601 aaatctcgaa cccctcaaag tcatccatga gggtttaaat cagcttcttc caaattcctt
    12661 ttaatgttga tgttttgacc tcgtcccatg aatcatgaat gttcatggta tctagaataa
    12721 tgaatcatct ccagaaggtt ttcatttact ttgcccagat ccatcagagg aaccactgtc
    12781 tgtggcagct atagccttat gaaaagtatt tcttttgttg ttgttgtttg ttgttttttt
    12841 tttgagacag agtcttgttc tgtcatccag gctggagggc agtagcgtaa tctcagcttc
    12901 ctgcaacttg cgcccctggg ttcaagtgat tctcgtgctt caacatccca agtagctggg
    12961 actatgggca tacgccacca cacccagcta atttttgtat ttttagtgga gatggggttt
    13021 caccatgttg gccaggtctc ctgtctcgga ctcctgtccc caagtgatcc acccgcttca
    13081 gcctcccaaa gtgctaggat tacgggcgtg agccatcgtg tctggccaaa aagtatttct
    13141 taaataagac ttgaaagtca aaattactcc ttgatccatg ggctgcagaa tagatatttt
    13201 gttagcaggt atgaggacat gaatctcctg tacatctcca tcagatctct tgggtgacca
    13261 ggtgcattgt caatgagcag taatattttg aaaggaatcc ttttttctga gcagtacttc
    13321 tcaatagtaa gcttaaaata ttcagtaaac catgctgtga acagatgttg ctgtcatcta
    13381 ggcttttttc catttatagg gcacaggcag agtagattta ggatagtttt aaaggtccta
    13441 ggattttcag aatgataaat gagcattggc ttcaacttaa agtcacccag ctacatttag
    13501 tccctgataa gagaatcagc ctgtcctttg aagctttgaa gccaggcatt gacttctctc
    13561 tagctatgaa agtcctagat gtcatcttct gctgatataa agctgtttca tctgcattga
    13621 aaatctgttg tctagtgtag ccaccttcat caatgatctt agctaaatct tctggataac
    13681 ttgatgcagc ttctacatta gtacttgctg cttcaccttg catttttatg ttatggagat
    13741 ggcttctttc cttaaacctc atgaatcaac ctctggcaac gtcagacttt tctcctgcag
    13801 cttcctcacc tttctcaacc ttcatagaat tgaaaagagt ggaggccttg ctctggatta
    13861 ggctttggct taagggaatg ttgtggctgg tttgatcctc tatccagact attaaacctt
    13921 tctccatatg agcaataaga ctatttcacc ttcacatcat tcatgttgtt cactggagta
    13981 gcacttttca tttccttcaa gaacttttcc tttgcattcc caccttgact gtttggcata
    14041 agaggcctag cttttagctt gcctcagctt ttgacatgcc ttcctcacta agcttaacta
    14101 tttctagctt ttggttgcaa gcttctccaa cccaccttat tttattgttg ttgttctgtt
    14161 ttgttttgtc ttaggctttt agcagcctga agccatggct tttagtttct gtctttagta
    14221 ataagcagaa aagagggata aggaaggggt tttactggcc caaccagaaa cagaaactaa
    14281 gaatccatgc ctatattctc tcccttggac actcctgaaa gtgagagact tgcgactctt
    14341 cctttcacct agagggcatt cattataggg ttattaatta tagggaacac ttagagggca
    14401 ttatagggtt aataattggc ctaatagtgt tgtgtctcag ggaataggga ggcccaagga
    14461 gatggggaga aatgggggaa tactggttgg tggagcagtt agaccacaca catagcattt
    14521 atctattaag tttgccatca gatcttgtga gacttattca ctatcatgag aacagtacaa
    14581 gaaagacctg cccccatgat tcaattactt cccaccgggc acctcccaca acatgtggga
    14641 attgtgggag ctacagttca agatgagatt tgggtgggga cacagccaaa ccatatcacc
    14701 atctcatagt gagcacatgc tgttggaaaa tggtaccaat agaattgctt gactggggat
    14761 caccacaaac tttcaatttg taaaaaactc tttatttgca aagtacaata aagtgaagca
    14821 caataaaatg aggtgtgctg gtattatggc caaagagtaa taccgtttcc tcttaggatt
    14881 taagagaact atattcaaga aaggtcacca ttgtatgaga ttttttttaa acagcttatt
    14941 aaagtgttag gttcatgaaa agtagcgtac ataatttatc caaaattaat aaacttttat
    15001 gcaattgtaa gtcttcagtt gaaacaacta catgggtact aacttaagtg tttccacaca
    15061 ttcaccatcc ttgtttgacc aaaagtgaat cagaagtaac ggctcacctt gaagatattg
    15121 gaagaatttg taagtactgt taagatactt gttgaaaata agtgtaaata tactttgttt
    15181 aaataaacaa acgagcttat atcatttaat tgtagcctcg agacaattct aagacagaag
    15241 tagaaaggat atcatcagtg ttgcagggct catcaggctc aggaatgctg attttcatca
    15301 acacataggc ccaaagaatg aattccagca taccaaataa atgatataga atggaaagag
    15361 agctgtcagt caggccatgt gtttgtattg gtttgactga cacattcttt ccatacaggc
    15421 aggctacaat tgataaccaa ttatttgagg gttgattaca taatggaacc atattatggg
    15481 atttaattat atgtagtgct tttaactctg tttcagaaag aaagacagaa atatgactcc
    15541 tttttcacca ctgaatcggt aacatcatcc ataggctgtg ctcagaatat gaatgcatga
    15601 atacatacag ggcaaactga acttctggat gagcctgatg aagccctgtc acctctgggc
    15661 agtgtagcat gtgactcagt tattgagagt acagactctg gagccagact atctttgttc
    15721 aaattctttt atttttttca gacagagtct tgctctgtca cccaggctgg agtgcagtgg
    15781 cgcaatctcg gctcactgca acctccacct cccgggttca aacgattctc ctgcctcagc
    15841 ctcctgagta gctgggatta caggcgccca tcaccatgcc caactaactg acctcatgat
    15901 ccacctgcct tggcctccaa aagtgctggg attacacgtg tgagccacca cacctggcct
    15961 agttcaaatt cttgttctat tactttgctg tctgaccttg ggcaagtttc ttaacctctc
    16021 tgtttcagtt tcctcacatt taaggcaagt agtagttcat atttcacagg attattccaa
    16081 agattaaatg tgttaataaa ttacagggct tagaatagta tctaacacac agtaatcact
    16141 atagaagtct tgttgctctt ttattttagt gttccttaac taagtactgc aacatcttcc
    16201 tacaagcagt tctccttttt ctgtttccat tactgtctct tacccctccg tcatgtacct
    16261 gcccacaaat gccttattga tacattcttt atattaatat gttcaattaa gttttaagct
    16321 agcctgagac ccattctgtc tcttgaagga actttgccta ccactactca tagccatcat
    16381 atgttgattt atagtttaat ctcataggac aattttattt ttaatttctt aagaggaacc
    16441 ttgattctgc tcatcgtgac ttttgctcat cccccaaaga ctgccttcag aatcctatca
    16501 tttctatgta tagtcattac cacaggctat ataaatgtct acccatttgg taaaacaaaa
    16561 ggtagatcat aaattattaa ttgttatcaa gattcgatta taacatcttc agtgagcatc
    16621 tgctacttat gaaagagttg aacttatttc caaagatcat gatagaataa aacatgtcag
    16681 atggcatttt tagaatttcc agactacttt tgtaagaagt tagctcacta tgaatgaaag
    16741 catttataga taacgttaat ggttactgac atgacattta tttaggtcaa atgctggagc
    16801 ataaatcaat ggagatccca aataaaattt tcattggtaa acaaagacaa aacagtattt
    16861 caaaatgcca catttattct tttaatgtta aaatatcctt taaaaaatag tagtgatagt
    16921 gatggcccat gcttataaag agcttactat gcgccaaaca gttctataca cttaataact
    16981 tttagtttgt ttaatcctta ccacaaccct atgaagtatc attgtttaca ttttgcaagt
    17041 taggaaacta agacaaaaga gattaaataa cttccccaca actgcaaact agtaattata
    17101 acaaataaca tctaacattt acatagctct tactatgtgt gagacactat tctcagtgct
    17161 cacaagcatc catgaggcag gtactgtgct tacctcgttt gagcactgaa aggctaagta
    17221 cctggcctaa ggttacatac ttctaattag tgggtaaagc caaaagtcaa gcactacact
    17281 cttgactaag ggactatttt gagtaagagg cagtcagggg atttttattt ttaatgtctt
    17341 aagaagttgg tgattctgta ttggtcccta aagatcattt tcagtttttt gtagtaaatg
    17401 gaatcttgaa atctaagaac tgatgagcta agcagtgtcc tagagtagca actctgagtt
    17461 cacaccttat ccagtgtaat attagaaacc ttgttttaaa aatgcactat tttgatatat
    17521 ttttggtttg acagaagaca gctgctgaaa ctctttctct ctcatcactc ctgttcagcc
    17581 gatgtctcac ccaagcccat gtagtcaaca taaagaaatg agaaattgcc agctcttggc
    17641 tcttatgcct cttcaaagat taatgagcat tcaggctgct tagaaggcat ccagctgtgg
    17701 gtgagatggg cttccagcct ggcagagtaa acactgaggc ccgcagtctt gtcccagctc
    17761 tgctgctggc gtgctatgag atttcccagc catctggggt cttattgtct tattttaaaa
    17821 tggaaagaat cctgagtcaa cagcaacata tgaagtggtt gctgtgttcc aggggctttt
    17881 acagatatta gctcagtgaa ttttaatcct cagaaccacc ctgtgcagct ggtggtatta
    17941 ctcccatttt gcaatgaaaa ccttgatgtt ctgagagatt aaatgactag taaagatggg
    18001 attgaaccat ggtcctccct ttaacatgat agattagtcc acatcatcta caagtcacct
    18061 ccaatattaa gtatattcaa ttctataatt tcatgttgaa ttctttttaa gagatggggg
    18121 tcttgctatg ttgcccagac tggagtgtgg tgactgttca cagacaagat catagcatac
    18181 tacagcctct aactcctggg ctcaagagat cctcctgccc cagccttctg agtagctggg
    18241 aatataggta tgcaacactg gcccagcatc attctgaatt cttaaatggg gtcattttta
    18301 gaaattctta tctatgcttt gggtctagac tttttttcct aatctgctac aacccagtta
    18361 taacctcatc ttgactttta aatgttttta gattttaata tcctctttat agtaatttaa
    18421 ttacaatttt gccataatct ctgttaacta tgatttaact tttgcacatc taatgtgccc
    18481 aattcttgat tatcttttaa tgtttttaat ttttttaatc gtgtgatttt tcagggttat
    18541 gtttactact tagtgaattt taggcacagg gtgcacagtg catgtataca cttgaagggt
    18601 tctctgatgc ttttgcttac acaaactaaa ttaatagccc cccttctgct atactcataa
    18661 ttatgaaaaa aagagtgaag tgctgcaata aaagcatacc tgatgcatga aattataata
    18721 gaagcaaata aaaaagaaaa ctttttctcc cctaaattaa tatataatat ttctacaata
    18781 gaaattcatc tcttggtgat acatttagga gattttatat acttaggaaa ctaaaattgc
    18841 ctttagctac aggtaagctg cctaaatagt agtagaaatg gagagaagtg gggtgaaaaa
    18901 caaatattta tgaccaaaag gaataaaaac ttagctgtct ttgaaaagat aaatttgatt
    18961 cacataggat agtattatat tattttctct tcagaacaca atttgtcata gaatggatca
    19021 tagtctgaat gaacactgaa taattttttt aggttaatcg cccttaccta aaaagaactt
    19081 tgggatacat aaaaattaga acatcaagta aacaacttct tacaatactg aagcctactt
    19141 aataagagaa atgccgttgc ttgaatcagc catcggctga tgactcatct cttaaagtag
    19201 gcctcaacta ccgagcaaag agatccttgc ttggagggtt atgtataata taagagaaag
    19261 gaggttgcca tcttgtagcc tttaagtgat aacttttcgt gttactggta cactccagta
    19321 ggattctctg gggccagcta aatccacctg gcatgaattt caaaatgccc catcataagg
    19381 tagtctattc acagttggag gtctagccct tactcccatt tcctctctct attgatgtgt
    19441 agctgttgta ggacactcag atctctatta tagtccactg tggtctgttc attacccaag
    19501 gaaatggttt ctccacagtt cttgttctca gtttcttact aagttgtcag tcacattgct
    19561 taaaactttg accaccaaaa tatcattgct ccctagcttt ggaaaatgta tttataattc
    19621 ttcaaaaatt aaaatattaa ataaattgag agatccatta attcatttct accaaataat
    19681 tgttgagcac ctcctaatgt ttaatttctc ctttcctcct tcctagtcta cggaaatggg
    19741 cattagtgtc tccttgcaaa ctcagacaaa ctaatagctg aagggggtag tggatttatt
    19801 tgtaaagtta ttaatttatg tactgcttgg agcaacaaaa gtaatatctt attcctaaag
    19861 ggccttttga ccgggcatgg tggctcactc ccataatccc agcactttgg gaggccaagg
    19921 cagcaggatc acttgagcct aggagtttga ggtcagcctg ggcaacatag tgaaacccca
    19981 tgatttttca tttaaaaaaa aaattaaaaa taaaacagag ggccgttcca tagttttcat
    20041 tgtagcagaa taaataaata tctaatttgt cagcaaaata tgtgaaagca agatcttatg
    20101 ataacctcac ctgggaagta agaaatatat gtattttggt atgttaatgt atgggtgaca
    20161 gaacaagctg cagaggagac taataattta tttttaaaat atcaaaatat aggctgggca
    20221 tggtagctcc cgcctgtaat cccagcactt tgggaggcca aagcaggcag atcgttttga
    20281 gctcaggagt ttgagaccag cctaggcagc atggcgaaac tgtatctcta caaaaaacac
    20341 aaaaattagc acctgtcgtc ccaggtactt gcggggctga ggtggaagga tagcttgagc
    20401 ctgggaggtc aaggctgcaa gtgagctgtg atcacgtgac tgcattcctg cctgggcgac
    20461 agtgagaccc tgtgtcaaaa aaaaagaaga agaagaagaa gaagaagaag ggccaggcat
    20521 agtggctcac acctggaatc ccagcagttt gggaggctga agtaggagga ttgcttcagc
    20581 ccaggaattc aagaccagcc taggaaatat ggtgaaaccc tgtctctaca aaaaacagaa
    20641 aaactttgtg cgtggcagca caaacctgta gtcccagcta ctagggagga tcacctgagc
    20701 ctgcgaggtc aaggctgcag tgagcctaga tcacaccact gcactccagc cggtgacaga
    20761 gcaagaccct gtctcaaaaa aaaaaaaaaa aaagtattaa aatataaaag ttgggctatt
    20821 tctgtgttta taacaccttt ccttaatgag aggtgaattt ataggctgtg tcttcaaaat
    20881 gtataataat tgaacccaat attaaatata ataccagact catttctcct ctatttgagc
    20941 atttatctct atgaacttta atctatagcc atttaaactg ctaatattta aatataccca
    21001 aattatttcc tgtaaaatta tgggaaatta ttgtttttta atattttaat tttttaactt
    21061 gttctttttg aaataatttt agacttaaca aaaatattgc aaaaatggta ccaaaaaaat
    21121 ccattacacc tttcatccag attcctcaaa tgctaacatc ttacataatt accgtataat
    21181 tatttttttc aggaaaataa cattgataca aaactgttat ctaatttaca gatacacaca
    21241 ttcccactac tgtccatttt ctggcccagt ttccaatcca gaatcacacg gtgtgcttgg
    21301 tttcatatct ctttggcttc agccagtctg tgacagtttc tcagtctttg ttgaccttgt
    21361 gacttatgaa gagtactgcc catgtatttt gtagaacgtc ctttagtttg ggtttgtctg
    21421 atgtttcctt acagttcagt tcaggttatg tattttggtt ccgaatacct cagaaacaac
    21481 atcgtgtcat cctcagtgtg tcatatttgt tcccgttact gattatgtta actttgatca
    21541 cttggctaag gtgcagtctg cctagtttgt tcactgtaaa gttactgttt ttttccattg
    21601 tgatatttac taggagattc tctgggacca tgtagataac ctgtttttca atatgattac
    21661 aaggtcccac agtatctccc tttcacccac aaatgttagc atccatataa atacccaaag
    21721 acaaataaag agataaatgc cattcattga atcagtcatc agctgattat tcatctctta
    21781 aattaggcct catcttcaga gcaaggagta aaatgtttag tagtcttaaa cgttttgatt
    21841 ttaagaaaca aaagtaaaag gagcacatca tttgaatatg atgaattatt ttggaacaaa
    21901 gaattaaatt gtttgttata tgcaaataaa tacataaaaa acaaccaaga aaacctcata
    21961 aaaatcccca gaatcactgg ataaaaattt aaaaataaag aaagtgcaat cccaataaga
    22021 ctttaatgtt gaccattcat taggaaaaaa gcctactgca atagtcctgt cgataaaaaa
    22081 aagaagaaat tgagaaaata aaaaagccaa ctattagaag aatttagggc ctaaagaaaa
    22141 ttatatttct ttttcttttt cttttttttt tttttttttg tgacagagtc ttgctctgtc
    22201 atccaggctg gagagcagtg gcacgatctt ggctcactgc aacctccacc tcctaggttc
    22261 aagcaattct cctgcctcag cctcccaagt agctgggatt acaggcacct gccaccatgc
    22321 ccagctaatt tttgtatttt tagtagaaat ggggtttcac catgttggcc aggctggtct
    22381 cgaactcctg acctcaggtg atccacctgc ctcagcctcc caaagtgctg ggattacagg
    22441 cgtgagccac catgcccagc ctcataaatt attttcatac catatagaaa gcataatgat
    22501 aagaatatgc atactctacc atgtttattg ttatggaaat acagaagaaa ggcaattaac
    22561 tcaatctaag tagagttagg ggtgtggggc ctatcaacaa atgttttcta aaggaggtga
    22621 tagctgagca gtctttaaaa tgagtagaag ttagcaaggc agaaaaaaga ttatattccc
    22681 agcagaagtg acatcagagg ttcataagtg ataaacttgg gtttatgcat ggaattgcaa
    22741 accaatcaat attcctagag catgaagaaa aggtaaggta gctgagatgg ggaggattga
    22801 gcaagggcca gatcatggtg ggccttgtat gtaccacatt aaggctcttg gactttattc
    22861 tagggtagtg aaaagcaatt gaggatgatt aagcaggata gtggtattgt catgtgttta
    22921 tgtgtgtaga tttctttagc agccatgggg gaaagtgatt tgaaggagac agctgggtgc
    22981 aggcagacca agtaggagat tggaagtatc ccacagagat aaaactaatg gatgaaatag
    23041 ggaagtggta gtgggtcaga gccagggaca aatttgagaa atatttagga gcaaaatggt
    23101 cggaatttag ggattaatta gatgggaaga tgagagaggg aaacaaatct gagaagtccc
    23161 tagtttctag tttgcatgag taggtagcta atgtgacaca aaaatagaaa atacagaaat
    23221 agcaaatctg tccactcttc tctagcccac cacccaacat ctacctatct cctctttctc
    23281 agcagacaac cctgcctcct ctttcatcag gaaaattgag gacatcataa ttatctctct
    23341 taactagctg ctgtaacatg tacctactct ctgtctggtc cctcacccat ccttatctct
    23401 ttccaagctc tcaaacattg agtgatcttt cctggctcaa ggttaaagcc caccacctgt
    23461 gcatcccacc tgcttctagg accttgttcc atgcattact tccttgcttt cctttattct
    23521 ccacttcatt cattattgct ttatcacctt ctcttcaaaa ctttcagaat ccttgtctat
    23581 actcactgta atcacttcct tacttctcaa cccattgcag tttgactaac aaactttcca
    23641 acacacatat gtacatacat acatacaacc caggtatctg aatcaaatga aattttttgg
    23701 gcccttaaag tttcttcttt tagatctgtg gttccttgac ggaggcactg tgggacatca
    23761 ccaaatattt taaatattta tgggaaacac tgatacttga tatctttcag gccctatgca
    23821 aactgcaagt tcaaagcagt acagtttcaa cattagatta ccctgcattt atttgaacaa
    23881 tatcaggact ttgtgaagct gggttttcca tggttgccgt gataaaatgc acgcactgca
    23941 caaaaatgag tgtggaacag gaaatgacac tgacagtgtc cactgattcc aaggtttgag
    24001 aagttctata gtgctcaaca ggtgcacaca tgctattaaa tatttgtgat tagttaagaa
    24061 tgaaatagga atatgagttt ttctttcagt gtctgtgtat ttttttaagt cacttttaag
    24121 ctgttaggac atagatactt attaggttgt ttagacctaa tgactttaaa aattgaactg
    24181 ttaagcattt cttttagctt gggagacact gaaaaattta caggaacact aaaggtgcta
    24241 agaatctctg acctacacct tggcttcgca gtattgaccc catggctttc accattacca
    24301 aaacacaggg agttgtggac atccaagacc aagacagtat aaatgtgccc ttgaatgaat
    24361 catacttcat tttgttaatt tgtgtggatc actaaaatta gaaagatatt cctttcacat
    24421 gaaagttaca tttgagaata gcttcatata ttttatttta atacattgac taaaacctac
    24481 tttgtttttc ttttcttttc tttttttttt tttttttttt ttgagacaac gtttcattgt
    24541 tacccaggct gaagtgcagt ggcgtgatct cagctcactg cagccttgac ttcctgggct
    24601 caagtgatcc tcctgcctca gcctgctgag tagctgcacc accatgccca gctaattttt
    24661 gtattttttg tagagatggg ttttcaccat attgtgtagg ctggtctcga actcctggac
    24721 tcaagcgatc cgcctacctc agtcaactaa agtgctggga ttacaggcat gagccaccac
    24781 acccagctgt atggcactct gaaattgttt gggcacatga tatatatgga cttaatgtca
    24841 aataaccaaa tttgagtctg atctgtacca tttcctatct agtgtcagct agctttatgc
    24901 aagtcataga acctctctca agatttcctt ttttttcctt cataaaattg gcctaacatg
    24961 gggaaggagg actggaagac tttctcatgc tcttaagaat tatacctgct tatatttcta
    25021 aaagagaaat acaaagtatt cgtatgctac caataataaa tattttaaac ataccataat
    25081 tatcatcatc attgctagtt tttctagccc ctcagattct gcatattgtc ttaaattact
    25141 aggttatcac tgaatcatta gtcattgcca gtgctagata ctgtccaagg caaacatagt
    25201 cctcaaaaca tagtcctggt ccctgtatgt tatataattt tagaataatg tcatataaat
    25261 catatggtac atgcacacat agtaaaatat atttttacgt tttgtgcttt aactaatatc
    25321 tgtttagtat ttgttaacca tggagttatg gaaaaactta agctctgaag tgagacagaa
    25381 ctttgttgag aactcgtcat tgccattaca agctgacagc taaagtgcaa tttcacaaat
    25441 gccaatgaga gaataatgaa ctcctcagag ttgttggggg ggttaatgat gacccatgca
    25501 aagtgcttat gtatcatgta tataaaaggc gttgaacaaa tgtttttatc cccagcagta
    25561 agaagcaatg aaagtaggct ttgggtatat ttgtgctgaa aattagattc tatcaggata
    25621 taaagaaatg gtttaagcaa gttgtaaaga atctaggata agagtgacta attttaagat
    25681 gaattaaatg gtacttgttc tatttaatac atactagtga aaatatttca atggtactgg
    25741 ttgttctagg cagcacttaa tatgaaaaaa atgagttatg atacatgtct attcctttaa
    25801 tgaaaacttt ttaaaaatac agttaaaaag agagtaggct gagcacagtg gctcatacct
    25861 gtaatcccag cacgttggaa ggccaaggca ggtgaatcac ttgaggtcag gagttcaaga
    25921 ccagcctggc caacatggca aaaaccctgt ctctactaaa aatacaaaaa ttagttgggc
    25981 atggtggcac gcacctgcag tcccagctac tcaggagctg aggcacaaga attgcttgaa
    26041 cccaggaggc agaggctgct gtgagctgag atcatgccac agcactccag cctgagcaac
    26101 agactgagac tctgtctcaa aaaaaaaaaa aatggtaata caacacattc ccatttactc
    26161 accattcaaa actaacaaat ttcagctctc tgtcatattt gcttcagata tttaattttc
    26221 ctgttaaaaa aattaaatac tttcaataag ggtaaagctc cctttgtact gttttctagt
    26281 ccctttcatc ttccttcctc ctcagataca attgctatca taaatttgat gtggatcctc
    26341 ccattcaaat ttttatattt atactgatcc taaatatata tgtgtaaata atttttatga
    26401 ctgtactttc aagtttatgt atattttgtg agtgtcctaa tccttgcttt ttttaacatt
    26461 atatttttga gatataacat tcatggaatg tttataatgc cattcttcgt ttcttaattt
    26521 gtcagcactt tctcatccat tgagtcagat gaagagtgta atagcagctc acaccataaa
    26581 agggttgaga actactgact ttaaatgcct ttctggtttg aactaaacca ttattttaca
    26641 gagttccatg ctattcaatt atatttcttt gcttaagagt ttaaattcta gccagcattt
    26701 attttcagtg tggttaaaac aacaacagaa aaaaaggtca ggcatggtgg ttcatgcctg
    26761 taatcccagt actttgggag actgaggtag gtggattgct tcagccaagg agttcaagac
    26821 cagcatgggc aacatggtga aaccccatct ctacaaaaaa atacgaaaaa ttacctgtgt
    26881 gtagtggtgc acacccgtag tcccagctac tcgggaggct gaggtgggag gatcacctga
    26941 gccagggaag ttgaggctgc agtgagccaa gattgcacca ctgcactcca gcctgggcca
    27001 caagagttga gaccctgcct caaaaaaaaa acaaaaaaac acaaaactat cacattttgt
    27061 attatcatat gcaaattgat ctgcctacag ccaaagctta ccattaatct acagctatgc
    27121 cccatcattc aaacttgttc aaaagattgt attatagaaa ttttacttct agatagaatg
    27181 tggattaaat ctcattgtag attttgtata aaatgatgaa tttctgatac cacatacctt
    27241 tgttcaggct ttgtttgtct cttgtttttg ttgtgttgtt tttaacagct tcatcactgg
    27301 tccagctgta ataccagggt acttctccgt tgatgtgaat aatgtggtac tcattttaaa
    27361 tggaagagaa aaagcaaaga tcttttatgc cacccagtgg ttactttatg cacaaaattt
    27421 agtgcaaatt caaaaactcc agcatcttgc tgttgttttg ctcggaaatg aacattgtga
    27481 taatgagtgg ataaacccat tcctcaaaag aaatggaggc ttcgtggagc tgcttttcat
    27541 aatatatgac agcccctgga ttaatgacgt ggatgttttt cagtggcctt taggagtagc
    27601 aacgtaagta caaaatatga ttaaacattt ttaggcccta acacctgaat ttctgaacca
    27661 ggaagactta ttcaaaattg taataaattt agttcttctg ggattattga ggccaggtac
    27721 agtctttctc agagataaaa acagggtgtg gtcgcatcct tcaataacaa ttatgatgtt
    27781 tttaagagta ttttattctt taatgaggag atgagttact ttttttcttt taaaacccca
    27841 aggcatagaa tggatttttc aagcttatta ggagtgccat aaaaatatat ttagcagaga
    27901 aatggcagat agattttttt aaaaacaatg atagtatcta tatatagtaa aaaaaggcaa
    27961 tattattata tcaggaatat accgtaccat tgtgtttgag actggctgaa tttatacaaa
    28021 tctcttctat aaaaggaggg attaattaaa tgatagctaa ggtttctcaa gatacagtct
    28081 tttaggccag gcgcagtggc ttactgcctg taatcccagc actttgggag gccaactagg
    28141 cagattgctc gagtccagga gttcaagagc atcctgggca acatggcaaa accctatctc
    28201 taaaaaaaaa aaaaatcaaa aattatccgg gcatggtgac atggactcct gtatggcgcc
    28261 tctagtccta gctactcatg aggttgaggt gggaggatca cttaagccca ggagattgag
    28321 ctgagattgt accactgcac tctagcctgg gcaacagagt gagatgagac tgtctcacca
    28381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaag atatagtctt tctccagcta taaaatggaa
    28441 aacatatatt tttatctttc tgttaatagg atgtttttaa ttaagagcaa gttgacttta
    28501 agataagttg ccactagtat ataaacctcc tgagagcagg gatttttgtc tcttttgttc
    28561 actgttctat ccacagagcc taaaacagca cctgcagagt aggtattctg tatttgttga
    28621 gtggataaat tatgaaaaat ctcactgaca tgatttttga atcatacatt cattattcat
    28681 cattctgtcc ctggttgcgg gatgtggcct tagactgctg cctagttagc gacacagatg
    28741 tcactggcac atctgtgcca gtaatgagat gtattcccaa gcctactcct ataacaccct
    28801 aactcagtag gtttggggta aggccagaca aaaaggttct tgttaagtaa agccaggttt
    28861 aagaccctct taaaaatcta ttttttgagc agagcctgca tttgtaaaat gttttcatat
    28921 agtataagat ggaacctctt ggtaatcatg atgttgttgc actaggccag tatatttctt
    28981 atataggtct gtggttctca accaggggca attttgccca ccgggaggca tttggcagtg
    29041 tctggagact tttttttttt tttttttttg agacgaagtc ttgctctgtc accccagctg
    29101 gagttcagtg gcacgatctt ggctctctgc aacctctgcc tcccaggttc tagccattct
    29161 cctgcctcag cctcccaagt agctgggatt acaggtgggc atcaccactc ctggctaatt
    29221 ttgtattttt tatagagagg gggtttcgcc atgttggcca ggctggtctc aaattcctga
    29281 cctcaagtga tctgcctgcc ttggactccc acagtgctga gattataggc atgagccact
    29341 gtgcctggcc tggagacgtt tttgattgtc acaactggag gaaagaggtt gtcacaactg
    29401 gtatctagca gatagagccc agggatacag ctgaacaccc cacaatgtat aggacagcct
    29461 ccacaagaaa aaattaaccc aaaatgtcag taatgctgag gctaagaaac cctgttatat
    29521 acaaactgtt aggtaaaatt ttgttctcgt gtgaaagtta catttcaggt acacagttta
    29581 atccctggta tttccaaatg ctcataaaaa taggtaactt ttcctgtatg gcataccatg
    29641 gttttatctg tcagtttgtt ttaatctact tgaaaagccc ttgggattaa tttttcagag
    29701 ccctttgcaa tagcaaaata tataatcttt cctttttttt aattgacaaa tagtaatggt
    29761 atatgataat ggggtacaaa tgatgttttg aaatatattt acaacgtaga atgcttaaat
    29821 cagactaaca aatccgtaac cttatatact taacaatttt tgtggtaaaa acataacatc
    29881 tgctgtttta gcaattttga aatatacagt gcattattat ttattatagt caccctattc
    29941 tgtgtgatag atcactaaag cttattcctc ctgtccaact gaaacttcat acccttcgat
    30001 caacatcttc cttttcccca tccatctccc tcccctggag tattctgtaa tcttttcatc
    30061 acctggttaa aatgttgctt aaatcgtgat cattatgaat agagaagagt ctttatactt
    30121 tgaaggtttt gaatgtaaca tgcctaacag ctgcagatga gtaatgcaag ttaaagaatg
    30181 tcaaaaacaa ataactttag gcacaacatc tctgtaacac ttttgtaaga gatgtcagtg
    30241 tgaaattcaa tttttttaag tcagtagatt cagggagttt tccaaagtat tcatggaaaa
    30301 ttacaatttg agatttagaa atcacatttt aaacctcttc tgtatacttc ttgctaccta
    30361 agagattggg ttatggggaa tttttgccaa ttctatatca tatgttaatt catgtgtatt
    30421 tatttttata gatacaggaa ttttcctgtg gtggaggcaa gttggtcaat gctgcatgat
    30481 gagaggccat atttatgtaa tttcttagga acgatttatg aaaattcatc cagacaggca
    30541 ctaatgaaca ttttgaaaaa agatgggaac gataagcttt gttgggtttc agcaagagaa
    30601 cagtaagttc tatgcttatt taattcattc attttgttct ccagtctgag agttgcttta
    30661 tgtagaaaca caggtttcca aagaggcatt gttaactcta tttgtaccaa tctttcccca
    30721 gaagatacat tagtaattaa aactgtgaaa agactgggtt gtacacattt agaatagaga
    30781 gaaccgccta tgactgtagt ccatcttgaa gaggaacact ggtaactgtc atttgcaaat
    30841 ttcagttgtt agggtttcct caataatatt tgttagtcac acaggagatt atagatgcta
    30901 atgagatact taggttcatc actgagatgt tgtgcagtgg accaattcag tgttccaaga
    30961 ccggtgtgca ggtctcacaa attcaggaat tcaggaacct gacaccatct tcaggacatg
    31021 gaccttgtat tcttctgtga atccccagat ctaacatagg accttgcaca aagtagacct
    31081 aggataaatg gtgagtggat gaatggttgg atagggagac tcaatagggt taaatgtctt
    31141 cttttatgta gtaaccagga aacaggtgtt catgttgtga aggaagtaaa tttgcaatca
    31201 tttattttgt ttttaaatag acaaatcaag ttttcaaata aacaaagcat aatgcagagt
    31261 catcagggaa gtaatgcctt aaaaatgtcc agttaggtct ggaattttac tttttaaatt
    31321 atagcaggta ctctttattg ctaatgtaac catatcatat tcgttcagtc agtgtttacc
    31381 aagcaattgc tctatgccag aaacttgttt acccacagta aatacagcag tgaacaaaac
    31441 aaagtccatg ccctcctggc acttaaatgc ttgttggagt agacaagcaa gtaaaatata
    31501 ttgtgtgtca gaagatgata aatgccctgt aaaaaattaa gcagaagaat ggcatagaaa
    31561 gagcttgggt gttggtggtg gagcatttgc tattttggaa tagccaagaa aggcattcat
    31621 tagaaggtta catttatgca caggccttaa gaatgtgcat gggtgagtct tgtgtatatt
    31681 tgggagaaga ctattccaga cgtagggaag agcaaaggcc ctgaggcagg caggaatgtg
    31741 cttactatgt tacaggaaca acagggccag tatgtctgga gtggaatgaa tgaggacagt
    31801 gtaaaataac aaaggttatt atgggaataa ttcttgtaac tcctctcata ccattgagcc
    31861 agaggtttga gtagatgttt tccttgtttc tcattgttgc ttctagacta ttctcccctt
    31921 tccctcccta ataatcccaa ttttgaaact catgtcagca gacaaaacca tccatcaccc
    31981 ttactctctg aaatcatgca cttacccttg ggtttctccc cctacttctt cgaagagttt
    32041 agctcctggt actctctagc tctgtctgac actactctgt tctcaattct tagtgactgg
    32101 caaatctaca tagatggtct ttctgtcatt ttggtctttg cagttccttc acctcccctc
    32161 ctccaataat ctgggcttcc acctgacctc agccattctc tctcatggtt atttcctaga
    32221 ctttgtcatt acacatactg caccttctga acatgatctc aagtcccagc atctctttct
    32281 acaaccacca tcatctgtca ttccagctca ttccgtgtaa taatctgact ctgacaattc
    32341 agctggcact tagaatctat tgttcctact acccttttgt tgtccttcac tcccctttct
    32401 tcattttatt cttcacctaa cttaaatttc attgtcaatc ataattgcct ataccttcag
    32461 ctccctaatt ccctaatctg gcaaaccata actctggtta aatccagctc tctgcctact
    32521 ccatgcctgc acccatgcaa ctacacataa ttggagaaag gtgctaattg acctttattt
    32581 aaacacgtga ctttgaacct caggtgccca gcagtcttat atttcccttg tccatatatt
    32641 ctcccactct cctagaaggc tgttttatac cttcttctct cctacactct aacacctccg
    32701 cctttcttac tttatgaccc tattgcttat ttcactgaga atagtcagga gaaagcatct
    32761 atcttttttt ttttcttttg agactgagtt tcactcttat tgcccaggct gtagtgcagt
    32821 gacaggatct cggctcactg caacctctac ctcccaggtt caagcgattc ttctgcctca
    32881 gcctcccgtg tagttgggat tacaggtgca cgccatcacg cccggctaat tattgtattt
    32941 agtagagacg gggttttacc ttgttggcca ggttggtctc gaactcctga cctcaggtga
    33001 tccacccgcc ttggcctcat gaagtgctgg gattacaggc gtgagccacc gcacccagcc
    33061 gcgtctatct ttctttactg atctttcagt ttctaccctt gcccctgtac agtccattct
    33121 caacacaata gccagattga ttctgatgaa acctacatca cgtcatgtca ccccatgatc
    33181 aaaagcctgc atgatagagt cccgtgtgac cattcagact ttatcttctg cgcctgttcc
    33241 ctcagttacc ctacctcagc caccctggct tccccgcagc tccttgaaca tgccaggcac
    33301 atgctgtctc atggccttca ctcttgcttg ctcttttatc ccgccagatc tacgtggctt
    33361 gctccttcat ccccaactct gtgctcagat gctgccgcag taagacagtc cctcatcact
    33421 tatttaagat tgcaacccta cccccttaga aactcctgct ctacttactc ctttgctctt
    33481 ttctcacagt attctacccc atctaaataa tttactgact tcacttggtc actatccatc
    33541 tccaccacta gaactagaat atatgctcca tgagggcaag gtagggaaga gaggacctag
    33601 cactcccaaa gtatcggttg aattattatt atccattcag aagtgttacg gtgactccta
    33661 gattttataa atgtacaact gtaaaatgtt ccaattcttc aacattttta agaaatctgt
    33721 ttgggccagg attttggata tctcttatgc ctatcatctc tataaagttt caccatttcc
    33781 tgaaactgat tttattaaaa gataaggtat ttttgttcac aaactatata cttagtaaag
    33841 tgaaaactac agttgttttt ctgattttct agctggcagc ctcaggaaac aaatgaaagt
    33901 cttaagaatt accaagatgc cttgcttcag agtgatctca cattgtgccc ggtcggagta
    33961 aacacagaat gctatcgaat ctatgaggct tgctcctatg gctccattcc tgtggtggaa
    34021 gacgtgatga cagctggcaa ctgtgggaat acatctgtgc accacggtgc tcctctgcag
    34081 ttactcaagt ccatgggtgc tccctttatc tttatcaaga actggaagga actccctgct
    34141 gttttagaaa aagagaaaac tataatttta caagaaaaaa ttgaaagaag aaaaatgtta
    34201 cttcagtggt atcagcactt caagacagag cttaaaatga aatttactaa tattttagaa
    34261 agctcatttt taatgaataa taaaagttaa ttatcttttt gagctaacat gtgattttta
    34321 aaatcatttt gactactggg tgtataaatg tgtttgtgtg tgtatgtatt tatagatgtt
    34381 ctttaaggta cccttgaaaa ctctacatta tgtatgccac ataatgacat ttcagtcagt
    34441 ggtagactac atatatgata gtggtcccat aagattataa tggagctgaa aaatttctat
    34501 cgcctagtga tgtcatagcc tagtgatgac atatgtattg caatacatca ctcacgtgtt
    34561 tgtggtgata ctggtgtaaa caaatctatt gcactgccag tcaagtaaaa gtacagcaat
    34621 tatgtcctgt acataatatt taataatgac aataaatgac tatgttactg gtttatgtat
    34681 ttactatact atacttttta caatttgtat tagttcttgc attgctatga ataaatgcct
    34741 gagattgagt aatttataaa gaagagaggt ttaattggct cacagttcaa cagactgtac
    34801 gggaagcatg aaaacttcag gaaacttaac aatcctggca gaaagcgaag gggaagcaga
    34861 catgtcttca cgtggccaga gcagagggaa aagggggtgg gtgctacaca cttttaaaca
    34921 accagatctc acaagcactc actaccagga aagcagcacc ataggggaaa tccacctcca
    34981 tgacccaatc tcctcccacc aggccctgcc tccaacactg gggattacaa ttcaacatga
    35041 ggtttgggtg aggcacagat ccaaaccata tcatcattat tttcgagtgt actacttgta
    35101 cttattaaaa aaaaaaaaaa agttaaacag cctcaggcag atccttcagg aggtatccag
    35161 aagaagaagg cattgctatc aggagatggc agctccatgc ctattattgc ccctgaaggc
    35221 cttgtggtgg ggtgagatgt ggaggtggaa gacagtgatg ttaatgattc ttactctgtc
    35281 taggcttagg ctaatgcggt tgtgtcttca tttttaacaa aaagtaagaa aataaaagta
    35341 acaaattttt taaattttta aatagactaa agtttataaa ataaggatat aaaaaatatt
    35401 tttgtacagc agtataatgt tttcagcagt gttattataa aataatcaaa aggtttaaaa
    35461 agttataaag taaaaattta cagtaagcta acattaattt attcgtcaag aaagaaaaat
    35521 attttctttt ttctttttct tttttttttt ttttttgaga cgaagttgtt cttattgccc
    35581 aggctggagt gcagtgccat gatctcggct caccgcaacc tctgcctccc aggttcaagc
    35641 gattctcctg cttcagcctc ccaggtagct gggatagcag gcacctgcca ccacgcccag
    35701 ctaatttttt atatttttag taaagacggg gtttcatcat gttggccagg ctggtcttga
    35761 actcttaacc tcaggtgatc catctgcctt ggcctcccaa agtggtggga ttacaggtgt
    35821 gagctatcgc actcagccag aaaaatattt ttttataaat ttagtgtagg ttaaatatac
    35881 agggtttata aagtctacag tagtttacag taatgtccta ggtcttcaca ttcactcacc
    35941 actcactcat tcactcagag caacttccag gcctgcaagc tccattcata aaagctctac
    36001 acagatgtgc cattttaata ttttatatca tatttttact gtaccttttc tatgtttaac
    36061 tacacaaata cttacatttg tgttacaatt gcctatggta ttcagtacag tgaagtgcta
    36121 tacatatagg tttgcatcct aggagccata gcctaggtgt gtagtaggct gtactattca
    36181 ggtttgcata agtacactct atgatgtttg catgacaaaa ccatgtaagg atgtgtttct
    36241 aaggacatac ccctgtcatt aagccatgca tggctatagt tctttagtat cttcagaaag
    36301 aattagagtc ccgcttgctg taagttgtct ggcatatgac ttggcatctt cagtgtgtca
    36361 caggccctca aatggctctt ttagccccac ctagatgtct tttgggcact taaaccacat
    36421 aactacaact gtattcgtta ttgtcttttt ccacaatata cacacacaaa cctatttcct
    36481 ctcaaacatt tttaatttca gtaaatggtt tcattagctg tttcccaagc tacaatctgt
    36541 aacatcatat ttattcctcc ctattccgcc aattaatcac caaattatgt gccttttacc
    36601 cccaagtctt cctagaataa ggcctctccc tccatcccca ccacctctcc ctcatttgca
    36661 gattttgtct tgtctcagag ggacaaccac aatagtgtgt cttccctgcc tctccaactc
    36721 tcagcactgc cttagtttca tgggtgcaag ttaatc
//

