LOCUS       NG_016761              19180 bp    DNA     linear   PRI 16-MAR-2010
DEFINITION  Homo sapiens VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
            (VMA21) on chromosome X.
ACCESSION   NG_016761
VERSION     NG_016761.1  GI:291084845
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 19180)
  AUTHORS   Ramachandran,N., Munteanu,I., Wang,P., Aubourg,P., Rilstone,J.J.,
            Israelian,N., Naranian,T., Paroutis,P., Guo,R., Ren,Z.P.,
            Nishino,I., Chabrol,B., Pellissier,J.F., Minetti,C., Udd,B.,
            Fardeau,M., Tailor,C.S., Mahuran,D.J., Kissel,J.T., Kalimo,H.,
            Levy,N., Manolson,M.F., Ackerley,C.A. and Minassian,B.A.
  TITLE     VMA21 deficiency causes an autophagic myopathy by compromising
            V-ATPase activity and lysosomal acidification
  JOURNAL   Cell 137 (2), 235-246 (2009)
   PUBMED   19379691
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AF003627.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a vacuolar ATPase assembly integral
            membrane protein. Mutations of this gene result in an X-linked
            vacuolar myopathy with excessive autophagy.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19180             AF003627.3         23719-42898
FEATURES             Location/Qualifiers
     source          1..19180
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq28"
     gene            5001..17180
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /note="VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)"
                     /db_xref="GeneID:203547"
                     /db_xref="HGNC:22082"
                     /db_xref="MIM:310440"
     mRNA            join(5001..5177,11447..11556,12732..17180)
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /product="VMA21 vacuolar H+-ATPase homolog (S.
                     cerevisiae)"
                     /transcript_id="NM_001017980.3"
                     /db_xref="GI:260436829"
                     /db_xref="GeneID:203547"
                     /db_xref="HGNC:22082"
                     /db_xref="MIM:310440"
     exon            5001..5177
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /inference="alignment:Splign:1.39.5"
                     /number=1
     CDS             join(5125..5177,11447..11556,12732..12874)
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /note="myopathy with excessive autophagy protein; vacuolar
                     ATPase assembly integral membrane protein VMA21"
                     /codon_start=1
                     /product="vacuolar ATPase assembly integral membrane
                     protein VMA21"
                     /protein_id="NP_001017980.1"
                     /db_xref="GI:63025214"
                     /db_xref="CCDS:CCDS35430.1"
                     /db_xref="GeneID:203547"
                     /db_xref="HGNC:22082"
                     /db_xref="MIM:310440"
     STS             6459..6591
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /standard_name="DXS7076"
                     /db_xref="UniSTS:98932"
     exon            11447..11556
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /inference="alignment:Splign:1.39.5"
                     /number=2
     exon            12732..17180
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /inference="alignment:Splign:1.39.5"
                     /number=3
     STS             16567..16773
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /standard_name="DXS963E"
                     /db_xref="UniSTS:99008"
     STS             16623..17723
                     /standard_name="G66661"
                     /db_xref="UniSTS:166900"
     STS             16808..16979
                     /gene="VMA21"
                     /gene_synonym="MEAX; MGC125514; MGC125516; MGC131652;
                     XMEA"
                     /standard_name="RH93612"
                     /db_xref="UniSTS:91009"
ORIGIN      
        1 ccttgtccag ttcctcttct ggtagcgtag cctctgggtg caggccaatc aggaaagact
       61 tgatccagga tctttcactt gggggttggt aactggagcg ctgccgcccc tcatgggcag
      121 gagatcctct ggttatatca aaccactggt gtgccagggg acatgggatc ctaggctgag
      181 ctggcaccac gctggacagg cagtgggggc catttcctga cccccattgc ctacttctgt
      241 ttgccggaag gcccacgggc tccactagag ccccaaaggt gagtcaagtt ggtgagaaca
      301 gtcctgaggc atgaaccctg agcattcctt gactccatgg gcaagtccct tcaccagctc
      361 agagatccca gcttagctat ctggcagata gagctggaag aggtagcctg atgtaaattt
      421 tagggcattc aagagtcagg aggcaagggg cattgtgagg tcctcaccag actgaaattt
      481 cccttagttt cactatttct acctggaaat gaaatgggga tggtataaat tgtagggatt
      541 gtgaatatgc tatttaaaat gaagcacaag acacatgctt tagggcagca gtgctggcca
      601 gaggttgatg tgaggtaagg aagacccttg agtaaaaccc aattcattgc ctggggcgaa
      661 gggcagcgtt gacaatggag gttttaacta taataacccc ttagttattt ttttttctat
      721 aaatggaact atgctttttc accagggggc atattttacc aatttttttt tttaagacat
      781 cacagcctac attacaaaga agccagagtt tctctctctc ttttttaata tgagttttgt
      841 tgattgtaca gtggagctta tttctatttt ccttatgtct tagttttaaa aacaccgtgc
      901 tgttcaggta taggccttgg caagtatcag ttggtgtttc aatatggttg ttccatccaa
      961 tcccacagcc agccacccaa aaggaaactt caagaaacga agttttttcg ggtaagtaaa
     1021 gcaatttggg gttgcaaaac gtgtctttgg gtgtatactt ttcacgtcac tgggttaata
     1081 gtacagaagt ttataacaat atggtggaga aaacgtgtct tacaagtagt acagaagttt
     1141 acaacaatat ggtggagaaa acatgagaca gaattaggaa ctatacattc tctaattcta
     1201 tcactgacct agggaatttg gggcaaatca cttcccatct ttagctgtca gttttctcaa
     1261 ctaaaattaa agtgccaaac tggggctctt tcagtttgag aatcagtttc tgactttaag
     1321 gggcattggg aagccttcac cagactctga aattttccct ggcctcagtt tttccactta
     1381 tgaagtgggg atggtataaa ttgtagggac tgtgaatatg ctcagtaaaa tgaagcacaa
     1441 gacacatgct ttagggcagc agtggtagga aaccactatt atggtttcct ctgtagtggc
     1501 cacaccccct aacacaccat ttcattccca tggcaacggc tctgtgtggg ctccacttgc
     1561 ctctaattct tttgtagcac tgcaggtagg aggtttcagg gctctgttga gagggctgac
     1621 tgctggctag attctttcct tctagtacag attctgagtt tatttttaaa gttctgtgtc
     1681 tacctcagta agctcacagt aaatgttggt agagtgtata agtcagcata aaaaagagat
     1741 atggcagggc gtggtggctc acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg
     1801 gatcacgagg tcaggagatc gagaccatcc tggctaacac ggtgaaaccc ccgtctctat
     1861 taaaaaaaat acaaaaaatt agccgggcgt ggtggcaggc gcctgtagtc ccagctactc
     1921 gggaggctga ggcaggagaa tggcgtgaac ccgggaggca gagcttgcag tgagcggaga
     1981 tcgcgccact gcattccagc ctgggcgaaa gagcgagact ctgtctcgaa ataaataaat
     2041 aaataaataa ataaataaat aaataaataa ataagagata tgagagcttt tgtttatatt
     2101 taaaaacact actatgtaaa ttacatgaga agtttttccc acagcaaatc tcatttatga
     2161 atggttcctg tttaagttat cacacaagtg caacttaggc tgttaatgtg ggagtgtaaa
     2221 agtgccagcc tgggagtcag gagtcaagct acatcccact agataaatgt gtgacttccc
     2281 acaagtcccg tcccctctct gggccgcagt tttctcatct gtacaaggaa gtgtttagac
     2341 tactgttatg ggttgaattg ctggcccggt cacccacacc atccccaaat tcatatgctg
     2401 aaatcctagc ccccagtacc ccagagtgaa acagcgtcgc tgcagatgta aataattaag
     2461 ttcatacagg tgtagggtgg gcccctaatg cattatgact ggtgtcctta taaaaaggga
     2521 aaatttggac agaaacacag acgcagggag aaggccgttt gaagaaaaat gcagagatca
     2581 gggtgatgct tctacaagcc aagaaatgcc aaagattgtc agcaaaccac cagaaaacag
     2641 aagaggggcc tggaacagtc cttccttcac aaccttcaga aggaaccagc ctcgccaaca
     2701 tctccatctc agacttctaa cctcctgaac tgggagatga ttaacttctg ttgttggagc
     2761 cacttagttt gtggcatttg ttatggcagc tccggcaaac tacaacaaca gtggttccca
     2821 gtttttttgg gggggggtgg acagagtctt actctgtcac ccaggctgga gtgcagtgca
     2881 gtggcacgat cttggctcac tgcaacctcc gcctcctgag ttcaagcgat tttctgcctc
     2941 agcctcctga gtagctggga ttacaggcat gtgccaccac gccaagctgg ttcccaattt
     3001 tttcaccatc aagaactatt ttgctctttt tccttttgtg gacccaattt atttatttaa
     3061 caaatattta ttagttccta ctatatacca ggccctactc taggtattgg ggaacaataa
     3121 gtcacaattc cgttccccca cttgtgttca ttctatgttt taaaagattt attctattaa
     3181 gtatactgtg gcttattttc ataataatct gtgaacagtc ttttcttatg ggataactag
     3241 gataacctca tcatgatata gtaagtgtca aaaatcaaag aacggtgata ttttaagtag
     3301 ctttggatgc ctaacagtaa atagattcat taggttttta aaaatattaa aaactgcctt
     3361 cagaaccacc attactacat ttatgggtcc ctagggattg aaggacctca ctgcaggctg
     3421 attagctaga gcaggggtca gcaaactctt ctgtaaaagg gtcagatggt aagaattttg
     3481 ggcattgcag atcattttgg gcgttgcaga tcataccgtc tctgtcacaa ctactcaaca
     3541 ttgctgttgt agataataca aacaaatgag aatggctgag ctccaataaa attttatcaa
     3601 tagacgctga aatttgaatt tcatataaat ttcacgtgtc atgttattct tttgacgttt
     3661 tcaacaattt aaaaaggaaa aaccattctt acctcagggc tgtagaaaaa caggtggtag
     3721 gctccatgta ttaggtcggc tggctcagtt tgcctacccc agaggtagat tctctttgta
     3781 ccccaagttc ttacattagg tggttcttac tcacctaaag gtctagatga ggcccagata
     3841 gagattacta ttatttttat taaatatttt acagtttgtt ttttagagac ggagtcttgc
     3901 tatgctgccc aagctgctct ggaactactg gcctcacgca atcctcctgc ctcagcttcc
     3961 caaagtgttg agattacagg cgtgagccag cacagtcagc cctagagggg gattattcag
     4021 tttgaactaa aacctggact tcctgctgcc cagtccattg ccctttccac cactctaagc
     4081 tgctggttta gtcatgattt cagatgtggt ctttgtatcc atgtggtgca gaaaatagct
     4141 gtgtggtcag cggccctttc caggcgctga ccatgttaag ggctgtcctc ttattagcag
     4201 ccagtggcaa cttaattttg tcaagcctga ctccagactt acccaccctt tcgtttttac
     4261 ctctctcggg ttgcgcaggc ccgggaggcc catctgttct tactatttga gtccctgttg
     4321 tctcattggc ggctttctga gcagctgcaa aatatgtttt taacttttaa gtggaagttg
     4381 ggggtcactg gcatcgagtc tggaacagtc attctcagca agagctcttt gaactctgac
     4441 attctctagt tttacggact cgggtgagtg ttttaactcc tcccagctgc caagggcttg
     4501 acttcctacc actgcgggca gtaattaatg aggcatttat ttgctcaagt agtggcgaaa
     4561 taatgcgcac tgcttttttg tgttgtcgtc ggcggaatac gctcagttgc ctagcaccac
     4621 agccctctgg ctggtagtcc ctcttcgcgg ctcatatgct cgggtctcct tgcggccccc
     4681 agctcagcga ccgagacgca gacgaggacc agtgttcacg cgagttcagg gggcggcgta
     4741 gccgccgccc gcccaggagg accatgttgc gcggcaagtc ccggctcaac gtggagtggc
     4801 tgggctactc gccaggcctg ctcctcgagc acaggcccct cctggcaggg cgcacgccgc
     4861 ggagccaccg ccggtaagtc atgtgagcgc ccgcccccgc gccggcaaca gccctgcgtc
     4921 gctgcggcgc gccgcgccgc gccgcgcctg cgtactgtgg cccgccgccc ggcgcgaacg
     4981 ggcacttccg gcgcgaacgg gcacttccgg cgcgaaccgc tacttccggt gcgaaccgcc
     5041 tcggccgttc cctcgcggag cttactgagc gcggccgccg agcccagctc cgccgccgag
     5101 cgcctgtgcc ggcacggcta caccatggag cgcccggata aggcggcgct gaacgcactg
     5161 cagcctcctg agttcaggta gccctgagcg gggcctggac cgcgaggcgg actggcccca
     5221 gcctggagca gggcttgagg gaaggcccta gctgaatggg tgggcgtgag gtctggaccc
     5281 cggggacctg gcctcaggga agggggcggg gaaagcaggt tggagcctga gacgtctaaa
     5341 ctcccggccc cgaactttcg ctcgggaaca agggatccgg ggtcatgggg aataggtcag
     5401 tgggccttca gctcatgctc ctatcctagc actttctctc gctgtgtcta tattgcagtc
     5461 tctttcatta ccgcagggtc agccttctga ggacaggaat gcagtctcct tcatctccgt
     5521 gttccctagg gggcctgcat agtcggggct taataaatgt ttgctgtatg aatgaaggag
     5581 tagaagggaa tagtcccctg gtgtgagatt gcttcacttg gggaatcagt aagatagagg
     5641 ctggtgactg agttgaagga atgtatgaga gagcaggtgg ttctggccca ccccagtagg
     5701 caagggagtg gtgagggagt tagctatcat tcgttaagac ctactgtatg ccaggctcag
     5761 tgcacgtgct ttacatacat tgtcagaatt cttaatttct ctaactgctt gatttcccaa
     5821 ttttgaagag gatgcagttg agggtaagtg acttgaaact gagggtgagt gattacagaa
     5881 ttaggcgaca aagttagtat gtaattgaag ctaacgtttg accaagctca ctgactccaa
     5941 agcccacgat ctttggagct ctgtgatgcc ttctctttcc gacagggtca ttgtgagttt
     6001 tttttttttt tttttaactt ttattttagg ttcatgagta catgcgcagg tttgttatat
     6061 aggtaaactg catgtcacgg gggcttggcg tacaggtaat tttgtcaccc aggtaataag
     6121 catagtaccc gataggcgtt ttttctgatt ctctccctcc tcccagcctc caccctcaag
     6181 tagaccgcac tgtctgttgt tcctctccta gtgtccatct gttcttgttg tttagttccc
     6241 acttatgaga acgtgcagta tttggttttc ttttcctgtc ttaatttgct tagaataatg
     6301 gcttccagct ccagtcatgt tgctgcaaag gacatgatct cattcttttt tatggctgca
     6361 tagtgttcca tggtgtatat gtaccgcatt ttctttatcc agcctcaatg tgggtttttt
     6421 tttaattatt catttatgag aataccaaca tatttttatt agatacactt acagcatagt
     6481 ccttctagac tgattctggt ttcctaatgg aatttgcagt gaaatcttga ctgtgggaga
     6541 aagaattcct gttgtcttac ttgctacaaa agggaatgtg gtaggctctg tctgctcaat
     6601 gttggctgca gaagtttgta tgaagtggga aaactaggtg gtgttataaa tggaggcaga
     6661 ttaaggttca tcctgaactt tttcctttgt gtgaggacaa ctttaattcc agcctttctc
     6721 attcctcact tctaacaaat ctctgctcag taacacccaa agatacatag gataaatcaa
     6781 ttgaatagca tcagttgctt tgtcttggat aagccactga ttttacccaa ggtggcttgc
     6841 atcagcaaaa ccaacagctc ttgtggctgg aatccaggga gaaaatgtcc tataaacagt
     6901 agaggaagtt tgctagtttt caaaagtttg tatgtacact ttgacttaat gcttagtccc
     6961 atattagtga ggtcacaaca cagaaaagta gtcacatttt tgaagtttga ggtaaagaga
     7021 gaagtgagaa ggaattagcc ataaattatt aaggtatgct gtgtatagat tgtgtggggg
     7081 ctagaaatta atatgtagaa aggttatatt tgggtggtgg gattataggt gattttgttt
     7141 actttaaaac atttttatgg tgttatatca tcttttcaat aataaacttt ttaaaagcca
     7201 gaccagataa tagatactca agagaggtca tgtaaagaac aaaacaatca gttaacactt
     7261 cctttctgtt cctttaacaa gttagataat ctgaaagttg cattcctaaa acatactttt
     7321 ttactcacca tagaaacacc aaagtcaagt gcttttttta gggtgcacaa aagaattggc
     7381 caattagtga ctctttgtat tttttgtaga ttctccactg cagacactca tactcttcat
     7441 gaggattaca caataaattt ctctaaaaat ttactagtag gaaacagttt aagggagctt
     7501 atgtatatta aatgagagtt gtatagctca gtaataacca aaatgaggcc tgctaaaaga
     7561 tgatccattt aagtaccaaa agaaaatatt agaacttttt tttttacagc agtaagcatt
     7621 taatttctca cacatgtgca gagcatgtga tcaagaaata ggcatgaggt tagttatatt
     7681 taatatatat tttactcaat gtttttgtgg gttttttgtt caggttcttt ttaaataaat
     7741 ttcattgtgt atatttgagg ttcataacat gatgttatgg catacatata gtaaaatgat
     7801 tactatggtg aagcagatta atatatctgt catctcacat acttttgtgt gtgtgtgacc
     7861 agaggcagct aaaatcttat ttacaaaagt ccctaatacc atgcaacttt attgcctata
     7921 gtcctcttgt acattagata tctcacttgt taatccatat atctactgct ttgtgtcctt
     7981 tgatgtatat cttcctattt cctcccctcc agcctcccac ccccaccgcc atggtaacta
     8041 ctgttttatt ctctgtccct gtgtagttga ccgttgacct tttttttttt tttttaaaga
     8101 ttccacatat aagtgagctc atgtagtatt cgtctttctg cgtttggctt attttactta
     8161 acatgtcttc caggtccatc catgttgtgg caaatggcag atgtcctctt ttaaggctga
     8221 ataaaatatt cccttgtata tatacactac ggtttcttta ttttgtctgt ctacatacac
     8281 gtaggttgtt ttcaaatctt ggctattgtg aataatgctg caatgaacat ggaagtgcag
     8341 atatttttac gaggtagtga tttcatctcc tttgcttata ttccagaaga gagattgctg
     8401 ggctgtgtgg tagttctatt tttaatttct ttaggaactg ttttccataa tggctgtacc
     8461 agtctacatt tccagtcaca atgtagtagg gtttcttttt ctccacactt ttacaaacat
     8521 ttgttatcac ttgccttttt gataatagct gtccttagaa gtgtgaggtt atatctcata
     8581 gtggttttga tttgcatttc cctgatgatt tagtgatgtt gagcacattt tcatttatct
     8641 cttggccatt tttatgtctt tggagaaatg tctgtccagc tgttgtccat attttaatca
     8701 ggtggttttt ctgctgagtt gtaagagttc tttataaatt ttggggtatt aaccccttac
     8761 aagataggtg gttcgcaaat atgttttcct agtctgtaag ctgccttttc attttgttga
     8821 ttgtttcctt tgcagtacag aagcttttta gtttgatgca agccgcttta ttttttcttt
     8881 tgtagcctga gcttttggtg tgatatccaa aaaatcatta ctgaggccaa tgttaaggac
     8941 ctttccctct gtgttctttt atgtcttaaa actttatatc tttatgtttt agttatttta
     9001 tccattttgg gttgattttt gtttatggtg taagagtcca gtttttttct ttgcatgtag
     9061 aaatcctgtt ttcccagtac cacttattga agggactgtc ctttccccat tgtgttcctc
     9121 ttaacacccc tgtcgaagat tagttggcca tatatgtttg gatttatttc tgggctctat
     9181 tctgtttcat tgttatatgt ttctgttttt atgccaatac catattgttt tgattactat
     9241 aactgtaata ttttaaatca gaaagtgtga tgcttacaac tttttcaatg ttgctttggc
     9301 tatttggggc tttttgtggt tctgtatgat gaattttagg attgtttttc tattttaatg
     9361 aagaatgcta ctgtaatttt gatagagatt gtgttatatc tgtatgttgc tttgggtgct
     9421 gtagacattt caacagtatt aattcttcca atccatgaac acaggatatc tttacattta
     9481 tttgtgtcat cttcaatttc tttcatcagt gttttatact tttcagtgta caagtcactc
     9541 atcgccttgg ttaaatttat tcctaagttt cttttttttt gaaatagagt cttgctctgt
     9601 cacccaggcc agagtaaagt gccccaatca ctgctcactg cagccttgac ctctggggct
     9661 caaacaatcc tcccacttca gcctcttgag tagctgagat tacaggcacg tgccaccatg
     9721 cccagcgaat tatcaaaatt tttttttgta gaggtggggt tttgctgtgt tacctaggct
     9781 tgcgtcaaac tcccggcctc aagcctcagc cttcccaaag tgctgggatt acaggcatga
     9841 gccactgagc ctggccccta agtatttttt tttaatgcta ttataaatga gattgttttc
     9901 ttgatttctt tttcagctca gtaaaggatg cggaagtttg tcaagtgctt tttctgcatc
     9961 aactgagatg atcctacttg gtcataatat ataatctttt tgatgtattg gttttgtttg
    10021 tttgtgacag agtcttgctc tgttgcccag actggagtgt gattttggct cattgcaacc
    10081 tctgcctccc aggatcaagg gattcttgtg ccttggcctc ccaagtagct gggactatag
    10141 gcacacgcca ccactctcag ctaatttttg tatttttagt agagactggg ttttgccatg
    10201 ttggccaggc tgatctcgaa ctcctggcct caagtgatcc gcctgcctcg gcctcccaaa
    10261 gtgctgggat tacaggtgtg agccaccaca cctggcctga ttattgttga atttggtttg
    10321 aaaatatgtt attgaggaat tttgcaccag tgttcatcag tgatgttgtc ctgtagtttt
    10381 cttgctgtgt ctgtctggct taggtatcaa ggtgattgga gcctcttaaa acgtgtttgg
    10441 aagtattccc tctagctcga tttttcaccc ataacagaag ttcctattcc agctggggag
    10501 ggcgcactgg tccgttcgcc ctgcctacct ccttcagtgg tctggtgtct ggtgctggtg
    10561 gtcagggttg ctgcacgggc tcagggactg gtgtggcagt ggcttccctg ggccaaagct
    10621 ctgatcccag tgggggaggg cacgctggtg cgtcggctcc acctggttag tttgctggtc
    10681 cactgtctgg tgctggagga caggaggctg gcagctttcc cagatgcaag ctccgattcc
    10741 agcgggagag ggcacactgc tccacctgtg gtgcctgccg agttccctgg tctggtgtcc
    10801 ggtgctggtg gtcagggttg ctgcgtgggc tcagggacca gtgtgacagt ggcttccctg
    10861 ggcaaaagct ctgattccag tgtgggaggg tgcacaggtg tgtctgcctc gttagttccc
    10921 tggtccactg tctcatgctg gaggacagca agctggtcgc ttcccgtgac ggaagctctg
    10981 attccagcaa aagagggcgc gctgatccac ccatggtgcc tgctgcgttc ccagctctgg
    11041 tgtctggtgc tggtggacac ggttgccgca tgggttgggc actggtgccg ctgtccgccg
    11101 tggcttccct gggtaaaagc tccagttcca gaggcagggg cactgagttt cttcacttag
    11161 tttgttcacc cagcttgttg gcagttgatc tgaggtgccc tgacgcttcg tcttacactg
    11221 gatatgaatg acagtcccta aaggtggtgt ataatcttca tgttccagct caagaaattc
    11281 ccactaccca cagctggttc tctaggatct tcggattacg agtccctgcc tgtgatcttc
    11341 ctcctgcata gcatctcatt tgtggatgtt tatagtttca gggacataag agcgtttgga
    11401 tatgactgtg caggttctga ttttctcttt gtttacttta ttccagaaat gaaagctcat
    11461 tagcatctac actgaagacg ctcctgttct tcacagcttt aatgatcact gttcctattg
    11521 ggttatattt cacaactaaa tcttacatat ttgaaggtaa tcttagaccc attaaaacaa
    11581 gatgttttcc cccaatttaa gattctgtgc ttttatgacc tctttatatc tttaaactgg
    11641 gtattcttat ttttttcttg tttagctttt caaaaaatca tattgctcat aatgagtctt
    11701 tatgaaataa cttattgttt cagcttgaca gttttcctat ggttttctgt gaaatagctt
    11761 gcaaatcctt tctcttagta ccttttaaag aataggggtt ggctgacatg ggaggaggaa
    11821 ttttggggga atggacttta gtgtcagata acggaaggaa gagagaatga agtccccttt
    11881 ttgatgttga aatttttttt ttttttttga gacagtttca ctcttgttgc acaggctgga
    11941 gtgcaatggc gcgatctcgg ctcaccgcaa cccccgcctc ccatgttcaa gcgattctcc
    12001 tgtctcagcc tcctgagtat ctgggattac aggcacccgc cactacaccc gactgatttt
    12061 tggtattttt agtagagacg gggtttcgcc atgttggcca ggctggtctc gaactcgtga
    12121 cctcaggtga tccacccgcc tcggcctccc agagtgctgg gattacaagc gtgagccacc
    12181 gcacccggcc tgaagtcttt ataattatgg ttttgtttaa aacaatgttt gtttgtttgt
    12241 ttgtttgttt ttgagacgga gtctcgctca gtcacccagg ctggagtgca gtggtgcgat
    12301 ctcggctcgc gtcaagctct gcctcccagg ttcacgccat tctgctgcct cagcctcccg
    12361 agtagctggg actacaggcg cctgccacta cgcctggcta attttttttg tatttttagt
    12421 agagacgggg tttcacggtg ctagccagga tggtttccat ctcctgacct cgtgatctgc
    12481 ccgtcttggc ctcccaaagt gctgggatta caggcgtgag ccactgcacc cggccaacat
    12541 aatgttctta atatatagaa ggtactcata tcttttagtg aatactttat tcattaccac
    12601 ccaaaatatt actttttaat tgcctgacta gttaaataaa tacatcataa aaattaggat
    12661 gctttgtttt ttttttttgt actttggtaa attttgcaat aaaatggaaa ctgttttttt
    12721 tctcttgata ggcgcccttg ggatgtccaa tagggacagc tatttttacg ctgctattgt
    12781 tgcagtggtc gccgtccatg tggtgctggc cctctttgtg tatgtggcct ggaatgaagg
    12841 ctcacgacag tggcgtgaag gcaaacagga ttaaagtgaa catcaccttt ttatagcatt
    12901 aaattcattt tttaaaatga taaatgctgg agggggccat ctgatttgaa taaagttgaa
    12961 agaacatgtt aaagtcagtc ttaaggagtc acgtttgagt atgtaaattt tgatctttct
    13021 aatatgttgg tttgtatatt cagttttaac tgtatgaatc tgatttgcaa atgagaattt
    13081 ggaaaagtta gttacaaaga aatatgttaa tttaattaga caatactctg gaaggaattt
    13141 tatcttcttt caacaaaaca tgttttatag tattctgact tacggttgct tttgagtttt
    13201 actcatttgg atatattaag atgcacacag tgaagcaaat taaactccac tttacgctgg
    13261 aatgctttct ttagcatgaa aataccaggt ccttggattt gggattttaa tttcctatgg
    13321 aaagttgctt aaattgtgga cactggaatt aatctgaatg tcactgagga atttcacatg
    13381 aagtgtaatc cctagtcaat aagaattatc cattacatta ttttatggga aaactaggct
    13441 aaattacatc cattcaggta aaaggacctt agcttactga aggatctaaa gagcaaagca
    13501 aagatctcac tactcaaaca ctcagcctgc ttccttcaag tccccttgca ggccagcttt
    13561 gtgctttgca gaccaacttt ttaatgagat actttgcttc ctcattcaac attgaagcta
    13621 ggcttcaatt aaaaggttcg aggaagctcc atttaaaatt gtttttttta ctatttttta
    13681 aaattgtagt gtatatgata ggaatttgca tttaaatatg ttcatttttg catatgttag
    13741 gagtggaaac aatctggaaa acattttttt ttcatccaaa aagtattctc cttgggcata
    13801 tctgatggaa aaaaaccttg attttatttt cgtatcttta gtctgtgttc tttctagtta
    13861 tttggtacta attatgtgca atctaaaaac actcccacaa gtatttgttt tttaattata
    13921 aaatcatagt atatgttctt tgtagaaaac tggaaaaata catattcaaa caggaaaaaa
    13981 aatcaaaatt ccccataatg ttgccatcta aaaataacct ctattttagt tgatatcccg
    14041 tattcatttt tgaaagccat tccttaatgc tagtttgata cacactaaaa gtttagctta
    14101 caagttcaaa ttctgccagc ttttcctgac agctatttgc atttttttca gatgagtgat
    14161 tattggccat tttctttttc tttttcttta ttttatttat ttattttttt gagacagagt
    14221 tttgctctgt tgcccaggct ggagtgcagt ggtgcaatct cggctcactg caacctctgc
    14281 ctcctgggtt caagtgattc tccacctcag cctcccaagt agctgggact acggatgcct
    14341 gccaccacgc ctggctaatt tttttttgta tttttttgta gagacggggt ttcaccatgt
    14401 tgtccaggct aatcttgaac ttgtgacctc aggtgatcca cccgcctcgg cctccgaaag
    14461 tgctgggatt acaggcgtga gctaccacgc ccggccttat tgaccatttt ctaaataagc
    14521 acattctatc tttattctct taaaattcaa attttctgtt actgataatc ctaatactag
    14581 gattcttgct taagtatgtg aaaccattac cgatttgttg ttcacattta ttttttatgt
    14641 tgtgaaactg gactaaagga atagagggat gattagtcat aaaagtcaaa tagcatttgt
    14701 gtttaactgt tgagaaaagt gaaagatcag tatgattatt atggaactgt ttttaattct
    14761 tgcttaaaga ctacaatttt agtataatga catttgagtc tagggtagta tgtggtagat
    14821 ttctagatgg tccctaatta agaagtattg ttgtatttag aattgtccac ctaatttctt
    14881 tttatataat gccaaggtat ttcttgtgct tttgggatct tatgctgttt gtaaaatgtt
    14941 actgtccaat gttggattat tgttttggtt tcaggcattt gctgaatagg tgatgataca
    15001 tgggtatttt tctgcaagta tttaaaccag gggcatatgc aaaggcagtt gtaatttcct
    15061 cttggaaaaa gcgccaaatg tttgaaggtt aaaatcaaat gctagggttg atatttaggc
    15121 ttataacaaa ataggcttgt tttcaaagca gttttttcct agagttttaa ctgttaactc
    15181 actagtttgc tgctgttttt aactatgtta aataacatat ggtatttggc aaatagattt
    15241 atttttcaaa atgtctcact agtttccttt tacacaatgt atatacttca agatgtatag
    15301 aaaggaaagc tacagttgag cccttataca tgttttaagg tagaaatatg ttccctattg
    15361 tttgaaaact gattgtaaga ataacctcag ttaggagata taacttgaag tgtcagtcca
    15421 aactactgat ttaaccctat ttacggtaac acattacctt cctcacctcc tgtttggccc
    15481 tggagaatgt agtccttttt ctcatttgtg ttgagaaatg aaaagtctgc tgtagaatgt
    15541 atctgatgtc attagttctt caaatggata ccattgtaca tataacagta gaatttggtt
    15601 tggggttgtt agtgaaaaaa aatttaaacc tgccattaaa aatccccatg tttcatggaa
    15661 atctaacaga aatacattgt aataattaga acattttgtt ttcttttttc tttttttttt
    15721 tttcgagacg gagttttgcc cttcttgccc aggctggagt gcaagggcgc aatctcggct
    15781 cgctgcaacc tccgcctccc gggttcaagc agttctcctg cctcagcccc ctgagtacct
    15841 cagatgacag gtgcgtgcca ccacacccgg ctaatttttg tatttttagt agagacgggg
    15901 tttcaccatg ttagccaggc tagtctcgaa ctcctgacct caggtgatcc acccgcctcc
    15961 gcctcccaaa gtgctgggat tacaggtatc agccaccgtg cctggcctaa taattggaac
    16021 attttcatca tgaaaatgtc atcagctttg ccaaaagaaa caaccaattg acttgtttgg
    16081 cgtttgtttt ccattttcat gtcaatttta tgtatacagt tagaataccc aaggagacca
    16141 ctaaaatcag ttaaacaagt agggtatata caaagaaaga tgaaacccga aagtacataa
    16201 aaaggattta aatccgattt tagatgtacc tagtgtgtat ttcttatctc tagacaagtt
    16261 catgtttatt gtttaattta tgcccaagtg aagttgtaaa cttatggttc aactctgaca
    16321 cagaatttgt cacttgtctg aggtcagtgg caggtttctc tgctgtcaag cactctgtgt
    16381 cacccaccag attagtataa ctattaattc agactgtact cctatgttta agataatttt
    16441 tacaagagct ggctgaagca gcacattagt aacctgacaa gatttctttt tcccttttca
    16501 gggggaaagg gtcaccttaa aaataaatta ttttcaggga ctttgggaat ctaatgataa
    16561 atattacaca taatctatga atagcttaat cctttatata ttccttaaaa taggaattcc
    16621 tcgacatcac tcctggccac actttccttg cctgtgttgt tgctatgtgt atttgaaagt
    16681 aatatctgca ttccttttaa gatgttctgt aagtcatatt tgtcagttat acagagtagt
    16741 cttccttttc cccacgttca gtgtaatctc actgaacagt aataatagca atagctaaca
    16801 acatctgcac agcaccttac agtttgcaaa gaacgttcac acattctcat ttgagttttg
    16861 catagtgaac ctgttacgag atgtctcttg acgtcgatgc taaaagtgtt agaatcttta
    16921 catcactaga gtcattgaat atgctgtagt attgaatagt gccctgacta gggggaggat
    16981 ttggatgtgc tgcatttcaa gccgtgtata atcatcaaaa tggggggctt gagttcttta
    17041 gctacttgaa tccgatttac ttctgttaag tgatgctttt ctaaccgttt tctggatgga
    17101 ttttgtattc actatattgt agcttgtaat ttgtataaat gtaccatctg atgtcattaa
    17161 aaaaagtgtt tgtagtgcta ctttgctgtg tcctgattca attaatgttt tattaaccgc
    17221 tgtgttttta aaaatttgtt tgcctgcttc tcattttata acatgtagaa tatgtacaga
    17281 gctcacttta aaaaatttgt tcgttggcct ctgtttgtgc tatgtagatt atatagagag
    17341 ctgtcaagga taagttttta tgcagtaaat gtcaaccaga aatgctcaaa ctgattggga
    17401 gtgtggggga ggggtgttga gctgtaaagg gctggttata cttcgtctgg ggtgggcttc
    17461 aaatgcccct aaaggagagt tgagaaatgt ggaaatagat aattcctgac gacgtccaca
    17521 tgccaccccc tcatgaccaa tgtcctgtgt cctctgtcct ctaatcaccc gttgattgca
    17581 ctccagctcc ttcctgtgct tctgaggact ccagctaatt cttactaata aatgttaata
    17641 tccccttccc aaacacattt gagacgtctt agtattaaca aattttatag gttatgagat
    17701 gtccagggaa ctcaggaaac aggtaatggc attgcagaaa ctacaggaca gcagttctga
    17761 aagtttactg caatcacctt gtaggattta ttaaaaataa ctgattgccc aaatgtaacc
    17821 cagaccttct gaatcggact ctctgggggt gggggcctag aaagctcttt ggggcagggc
    17881 gtggtggctc atgcctgtaa tcccagcact ttgggaggcc gaggcggcgg accacgaggt
    17941 caagagatag agaccatcct ggccaatgtg gtgaaatcct atctctacta aaaatacaaa
    18001 aattagctgg gcacagtggt gcgtgcctgt agttccagct actcaggagg ctgtggcagg
    18061 agaatcactt gaacctggga ggtggaggtt gcagtgagcc gagagcctgg tgacagagca
    18121 atactctgtc tcaaaaaaaa aaaaaaaaaa ttttggaaca ggcagtgatc aacatgaagc
    18181 tggattgaga actactgctg gagatttaga attgtgcctc ccagtgtatg tgtttaatga
    18241 tggacttgaa gatgtttgta taaagcctga agtaagcaca caccttatta ggcaaaggta
    18301 gaatgttgat aatgctatat cgaaggtgca atttaaaata aggagacctt tactgggttc
    18361 ctgacaatcc atattgactt tgcttcagtg ctaatgaatg atgttgaatg aaaattttag
    18421 tacggggaac agccaactta agacacaact gaggcgtgcg tagatagaca tggccactgc
    18481 tgtgcctgtg atgccttttt cttatttgga atcctcactg ctgtggactt tggagagaag
    18541 gaaaaccaat aggagtatgt gaatttgagg tttctaaacc agagaggtaa tggagaaaag
    18601 cagaaatggt ttctaggcac atttgtgcta ttaaccctct ggcttccctg ccccccatta
    18661 cctttcactg cttacgtgcc tgcacttcct ttcacatacg ccctgctctt gcgtccatta
    18721 aagatgcatt gaggttagcc cttttggtaa atacaggatg aaggtggaga acattagttc
    18781 gcaacctggc aacccaggga tgctttcctc caaaagagga tccagcagcc ctgagggaag
    18841 ggatactaca aatggcacac cctgcatctg tgtgcatctc accaccttca atgctcccac
    18901 ttcgggccag cccagattta ctcctcgcct ggagcctcaa attggtttct tctgcccttc
    18961 ttgcacctgt ggtcactttg ccacaaagca actagaagtt tcctttaaag ataatagatc
    19021 aggcatacca tgcctctgct caaaatcctc ccaatagctc cccatctcac tcaggaagat
    19081 ttagactcca tatgtggcct acaagccagg ccacttcctt tcacttcatt cccaccccac
    19141 ttgctcacca tttgccagcc tcctggactt cttggtgttc
//

