LOCUS       NG_007667              28297 bp    DNA     linear   PRI 23-MAY-2010
DEFINITION  Homo sapiens myosin binding protein C, cardiac (MYBPC3), RefSeqGene
            on chromosome 11.
ACCESSION   NG_007667
VERSION     NG_007667.1  GI:187960082
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC090582.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: MYBPC3 encodes the cardiac isoform of myosin-binding
            protein C. Myosin-binding protein C is a myosin-associated protein
            found in the cross-bridge-bearing zone (C region) of A bands in
            striated muscle. MYBPC3, the cardiac isoform, is expressed
            exclussively in heart muscle. Regulatory phosphorylation of the
            cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon
            adrenergic stimulation may be linked to modulation of cardiac
            contraction. Mutations in MYBPC3 are one cause of familial
            hypertrophic cardiomyopathy. [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28297             AC090582.9         17785-46081         c
FEATURES             Location/Qualifiers
     source          1..28297
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p11.2"
     gene            <1..2845
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /note="spleen focus forming virus (SFFV) proviral
                     integration oncogene spi1"
                     /db_xref="GeneID:6688"
                     /db_xref="HGNC:11241"
                     /db_xref="MIM:165170"
     mRNA            <2157..2845
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /product="spleen focus forming virus (SFFV) proviral
                     integration oncogene spi1"
                     /transcript_id="NM_003120.2"
                     /db_xref="GI:124028516"
                     /db_xref="GeneID:6688"
                     /db_xref="HGNC:11241"
                     /db_xref="MIM:165170"
     mRNA            <2157..2845
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /product="spleen focus forming virus (SFFV) proviral
                     integration oncogene spi1"
                     /transcript_id="NM_001080547.1"
                     /db_xref="GI:124028520"
                     /db_xref="GeneID:6688"
                     /db_xref="HGNC:11241"
                     /db_xref="MIM:165170"
     CDS             <2157..2476
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /exception="unclassified translation discrepancy"
                     /note="isoform 1 is encoded by transcript variant 1; SPI-1
                     proto-oncogene; hematopoietic transcription factor PU.1;
                     31 kDa transforming protein; 31 kDa-transforming protein"
                     /codon_start=3
                     /product="transcription factor PU.1 isoform 1"
                     /protein_id="NP_001074016.1"
                     /db_xref="GI:124028521"
                     /db_xref="CCDS:CCDS44591.1"
                     /db_xref="GeneID:6688"
                     /db_xref="HGNC:11241"
                     /db_xref="MIM:165170"
     CDS             <2157..2476
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /exception="unclassified translation discrepancy"
                     /note="isoform 2 is encoded by transcript variant 2; SPI-1
                     proto-oncogene; hematopoietic transcription factor PU.1;
                     31 kDa transforming protein; 31 kDa-transforming protein"
                     /codon_start=3
                     /product="transcription factor PU.1 isoform 2"
                     /protein_id="NP_003111.2"
                     /db_xref="GI:124028517"
                     /db_xref="CCDS:CCDS7933.2"
                     /db_xref="GeneID:6688"
                     /db_xref="HGNC:11241"
                     /db_xref="MIM:165170"
     STS             2181..2398
                     /gene="SPI1"
                     /gene_synonym="OF; PU.1; SFPI1; SPI-1; SPI-A"
                     /standard_name="GDB:197862"
                     /db_xref="UniSTS:155976"
     gene            5001..26297
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /note="myosin binding protein C, cardiac"
                     /db_xref="GeneID:4607"
                     /db_xref="HGNC:7551"
                     /db_xref="MIM:600958"
     mRNA            join(5001..5080,6198..6464,7088..7201,7591..7689,
                     7781..7929,9162..9279,9798..9846,10023..10052,
                     10224..10277,10674..10676,11059..11076,11333..11496,
                     14079..14211,14441..14443,14558..14682,14768..14873,
                     14959..15125,15547..15712,16459..16565,16671..16700,
                     17913..18052,18299..18379,19024..19183,19909..20013,
                     20124..20312,21692..21826,22494..22661,23693..23781,
                     23951..24146,24370..24509,24730..24889,25001..25137,
                     25445..25631,25822..25858,25987..26297)
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /product="myosin binding protein C, cardiac"
                     /transcript_id="NM_000256.3"
                     /db_xref="GI:148596956"
                     /db_xref="GeneID:4607"
                     /db_xref="HGNC:7551"
                     /db_xref="MIM:600958"
     exon            5001..5080
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             join(5056..5080,6198..6464,7088..7201,7591..7689,
                     7781..7929,9162..9279,9798..9846,10023..10052,
                     10224..10277,10674..10676,11059..11076,11333..11496,
                     14079..14211,14441..14443,14558..14682,14768..14873,
                     14959..15125,15547..15712,16459..16565,16671..16700,
                     17913..18052,18299..18379,19024..19183,19909..20013,
                     20124..20312,21692..21826,22494..22661,23693..23781,
                     23951..24146,24370..24509,24730..24889,25001..25137,
                     25445..25631,25822..25832)
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /note="myosin-binding protein C, cardiac; cardiac MyBP-C;
                     C-protein, cardiac muscle isoform; myosin-binding protein
                     C, cardiac-type"
                     /codon_start=1
                     /product="myosin-binding protein C, cardiac-type"
                     /protein_id="NP_000247.2"
                     /db_xref="GI:148596957"
                     /db_xref="GeneID:4607"
                     /db_xref="HGNC:7551"
                     /db_xref="MIM:600958"
     exon            6198..6464
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     exon            7088..7201
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            7591..7689
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            7781..7929
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            9162..9279
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     exon            9798..9846
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=7
     exon            10023..10052
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=8
     exon            10224..10277
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=9
     exon            10674..10676
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=10
     exon            11059..11076
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=11
     exon            11333..11496
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=12
     exon            14079..14211
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=13
     exon            14441..14443
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=14
     exon            14558..14682
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=15
     exon            14768..14873
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=16
     exon            14959..15125
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=17
     exon            15547..15712
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=18
     exon            16459..16565
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=19
     exon            16671..16700
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=20
     exon            17913..18052
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=21
     exon            18299..18379
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=22
     exon            19024..19183
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=23
     exon            19909..20013
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=24
     exon            20124..20312
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=25
     exon            21692..21826
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=26
     exon            22494..22661
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=27
     exon            23693..23781
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=28
     exon            23951..24146
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=29
     exon            24370..24509
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=30
     STS             24418..24819
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /standard_name="PMC181559P1"
                     /db_xref="UniSTS:271674"
     exon            24730..24889
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=31
     exon            25001..25137
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=32
     exon            25445..25631
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=33
     exon            25822..25858
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=34
     STS             25980..26170
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /standard_name="MYBPC3"
                     /db_xref="UniSTS:73382"
     exon            25987..26297
                     /gene="MYBPC3"
                     /gene_synonym="CMH4; DKFZp779E1762; FHC; MYBP-C"
                     /inference="alignment:Splign:1.39.8"
                     /number=35
     gene            complement(27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /note="MAP-kinase activating death domain"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130476.2"
                     /db_xref="GI:209571516"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130470.2"
                     /db_xref="GI:209862970"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130471.2"
                     /db_xref="GI:209862974"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130472.2"
                     /db_xref="GI:209862978"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130473.2"
                     /db_xref="GI:209862982"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130474.2"
                     /db_xref="GI:209862986"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_130475.2"
                     /db_xref="GI:209862990"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_003682.3"
                     /db_xref="GI:209862993"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_001135943.1"
                     /db_xref="GI:209862997"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     mRNA            complement(<27672..>28297)
                     /gene="MADD"
                     /gene_synonym="DENN; FLJ35600; FLJ36300; IG20; KIAA0358;
                     RAB3GEP"
                     /product="MAP-kinase activating death domain"
                     /transcript_id="NM_001135944.1"
                     /db_xref="GI:209863001"
                     /db_xref="GeneID:8567"
                     /db_xref="HGNC:6766"
                     /db_xref="MIM:603584"
     STS             27672..27924
                     /standard_name="WI-20765"
                     /db_xref="UniSTS:53874"
     STS             27672..27922
                     /standard_name="RH76662"
                     /db_xref="UniSTS:89607"
ORIGIN      
        1 tcccagctac ttggaaggct gagacaggag aattgcttga acccgggagg tggaggttgc
       61 agtgagccga gatcgtgcca ttgcactcca gcctgggcaa caagagcaac tccatctcaa
      121 aaacaagaga atgggtgtga tgtgtgagtg tgagagcagg tgtgtgtgag catgcatgag
      181 tgtgagctgc tgtgagtgga tgtgagagca gaatgtgtgt gagcatttga gtgtgcaagt
      241 aggtgtctga gtggttgtgt gtgaacaggc gtgtaagcat gcaagtggat atgcatgagc
      301 agaatgtatg tgcatgcgtg agcaggtgtg aggtgcaagt gtaagtggtg tgaaatatga
      361 gtgagcaggt gtcaatgagg tgtgaaagag ctggtgtgag cgtgtgagtg ataagtgagc
      421 agctgtgagg tgtgagcatg tatgtgagca ggtatgtgtg atgtgtgagc atatgtgtga
      481 gcatgtgtgt gtgcagatat gtgtgggcag gtgtgtgtga gtgggtgtga gatgtgagca
      541 tgtgtgtgag gtatgaggtg tgagcatgtg tgaggtgtga gcatgtgagt gggtgtgaat
      601 gtgtgaggtg ttagcatgtg tgaagtgtta gcatgtgtgt gagcatgagt ttgtaagcat
      661 aagtgtgtgt gagacttggt gtgaggtgtg tgaggaagtg tgtgtatgga taggtgagca
      721 tgtgtgtgag cagacgtgag catgtgtgag tgggtgtgtg cgtgagtgaa tggtgtgagg
      781 tgtgtgagca caagtgtgtg agcaggggcg tgtgtgtgta gctgagtaat gtgagatgtg
      841 tgtgagcagg tgtgtgcgtg tggggctgag taacgtgaga tgtgtgtaag caggtgtgtg
      901 cgtgcaagtg tgtgtgaggt gtgggtaggt gcgatcatat gtgagtggat atgtgtgagt
      961 gaatggtgtg gtgtaagcat gtgtgtgtga gcaggggcat gtgtgtgcaa gggtgagcaa
     1021 tgtaaggtgt gagggtgagc agtgtaagat gtgtaagcag gtgtgtttgt gcaagcatgt
     1081 gtaagcaagt ataagcaggt gtgattatga gacctggtgt gaggtgtatg agcaggtgtg
     1141 tgaacatgag tgtgtgaacc tggtgtgagg tgtgtgtgag caggtgtgag tgggcatatg
     1201 agtgtgagaa ggtgcattgg gtgtgaccgt gtgtgggggc agtaagtggg tctgagtgtg
     1261 tgtgcatgtg tgtgagtggg tgcattgggt gggtgtgagt gtgcatgtga gtgggtgtga
     1321 atgaggtgtg agcatgagtg ggtgtgacca ggtgtgtgtg agtgggttgt gaatgtgtaa
     1381 gcagatgcag tgtgggtttg aacatgtggg tgggtgcaag catgtgagtg ggtgtgtcgt
     1441 gtgggtgcca gtgtgtgggg gcatgttagt gaatgagtgt gtgagcatgt gtgtgagtgt
     1501 gagctggtgc attgtgtggg tgtgtgagaa agtgacagtg tgtgagggca gatgtgggtg
     1561 tgaatgtgca agtgggtggg tgtgggtgca atctggcgtt tgggtgcatt gcacaagcat
     1621 gtgtgtgagc atgtgggtgt gagtctgtga gcacgtgcat tgtgtgtgca tgtgtgtgac
     1681 agcatgtgtg tgatcagata cattgtacgt gtgagcgtgt gtgggtgtga gcatgagtga
     1741 gtggttgcat tgtgtttaag catgagtgtg agtgggtgtg agaaggtgcg ttgtgtgagc
     1801 acgtgtgtga gtgggtgtgg gcgtgatgtg tgagcatgtg taaggaggtg tgggtgcgtt
     1861 atgtggatgt gagcatgtgt gtgtacttgg tgcactgtgt gggtgcgagt gtgtgcgcgt
     1921 ggggggggtg agtgcgtggg tgtgagtggg tgtgtgtgaa cgcctgtgtg tgcgcaagca
     1981 tgtgtgtgtg tgtgagtgtg ggtgcgttgt gtatgcacgc ccggcgcggg ctggggcagc
     2041 cgttcccctg cccttcccgg ccaccccgtc cccgggcccc tgtgcgtacg caaggcggtg
     2101 ggggcggctc ccatgtgggc cccgggcccc ctcccaccgg gccctccccc ccgcaggcag
     2161 caagaagaag atccgcctgt accagttcct gttggacctg ctccgcagcg gcgacatgaa
     2221 ggacagcatc tggtgggtgg acaaggacaa gggcaccttc cagttctcgt ccaagcacaa
     2281 ggaggcgctg gcgcaccgct ggggcatcca gaagggcaac cgcaagaaga tgacctacca
     2341 gaagatggcg cgcgcgctgc gcaactacgg caagacgggc gaggtcaaga aggtgaagaa
     2401 gaagctcacc taccagttca gcggcgaagt gctgggccgc gggggcctgg ccgagcggcg
     2461 ccacccgccc cactgagccc gcagcccccg ccgggccccg ccaggcctcc ccgctggcca
     2521 tagcattaag ccctcgcccg gcccggacac agggaggacg ctcccggggc ccagaggcag
     2581 gactgtggcg ggccgggcct cgcctcaccc gccccctccc cccactccag gccccctcca
     2641 catcccgctt cgcctccctc caggactcca ccccggctcc cggacgccag ctgggcgtca
     2701 gaccccaccg gggcaacctt gcagaggacg acccggggta ctgccttggg agtctcaagt
     2761 ccgtatgtaa atcagatctc ccctctcacc cctcccaccc attaacctcc tcccaaaaaa
     2821 caagtaaagt tattctcaat ccatcctctt gcagcacaga gtctctttta aaatttgttg
     2881 tgtatctctt ttggcccctg tgtgctgcga cgtctctttt tgtcatttgt ccatcgggtg
     2941 tttaccgagg actgtaccca atgctggacc ctgggaacat gaggaccaat gacacagagc
     3001 gcctgaacag gagttagagt ttggtggaaa gaacaagtcc tcaattgtga ttaggagagc
     3061 agatcctatt taaaagctct ctactcctga tagttgttgt ttttaagcct tgatgaggtt
     3121 tgaactcatg atgatgatga tgatgatgat gatgaccatg accagcaaca acatttgata
     3181 ttctggtcaa ttagtatctg ccaaccttga gatgtggagt ctaatatcac tccattttat
     3241 agaatgggaa actgaggctt gtagaggtca aattatttcc ccaaggtcac agccgttgag
     3301 tggccaagtt ggatcacact ccaggtctgt cccgacacgt caacatggag tgggaggcct
     3361 tgcttatctg gaagaggata ctcttcagca ttccgaggac aggaattaag ccccaaagct
     3421 cctgtgggcc gcaaagggtt ctcacgagct gcacgcccag caggacttta gacccaagtg
     3481 aatccctggt gggaccccca ggttctattt gctttctagc tcctagccac agcaggggag
     3541 aaacagacca agctgagcgg agaagcctgt aagtcctgtg ttttcctcca gacggtagca
     3601 agtagtggca gtagacagcc tgggagtgag ggacttccca acgctgtcaa agaccttagg
     3661 gaacccagat tctggggcca ttatcgtagg gacaaatacc cgccccacac ctcctcaacc
     3721 ccagagggct cactgcagcc caaccctgca gctccctagt cctactgcag ggccacaaga
     3781 gaaggcaaaa tggtgttgtg tcttcattct tctattttta tttttttttt tttgagacag
     3841 ggtcttactt tgttgcccag gctggagtgc agtggcacga acatggctca ctgcagccct
     3901 gaccccccgg gctcaagtga ttctcctgcc tcagcctccc gagcatctgg gactacaggt
     3961 gtgcgtcaca tgcctgactg atttttgtat tttttgtaca gatggggttt catcatgttg
     4021 cccaggctgg tctcgaactc ctgagctcaa gtgatctgcc cgcctcagcc tcccaaagtg
     4081 ctgggattac aggtgtgagc cacttcgccc agcccatttt tattttttta ttattattct
     4141 ttgagatatt aataataaaa aataataata aataatattt ttattattat tatcactctg
     4201 tcacccaggc tgcagtgcag tggtgcgatt ttggctcact gcagcccgga actccttgga
     4261 ctcaagcgat cctcccacct cagcctcctg ggtagctgat actacaggtc cacaccacca
     4321 cacctggcta atttgtgtgt gtgtgtgtat ttattttatt ttttattttt ttagtagaga
     4381 tggggttttg ccatgttgcc caggctggtc tcaaactcct ggcctcaaat aatctgcctg
     4441 cctcggcctc ccaaagtgct gggattacag atgagccacc acacccggcc taacattttt
     4501 aaaattataa acccacttca tacgtgtgac aatcctgtgc agtgggtgct gctttcaccc
     4561 accccgcttt acagatgagg aaaccaggtg ctttgagatt aaagagatgg cagtgctagg
     4621 actcagagac accctggccc cagggtctgt ggacatgacc actgcctgaa ctgcctgcga
     4681 ggatgctcct gacccgttag ccttagggtt atgggcccag catgctccca ccgtacaatt
     4741 tgctgtaaga gggacacaca cggggcttgg agtacccctg aggcttgcca aaggttgggg
     4801 aggcagaatt gtgctgcggg gggtgagggg ggaagggaca ggagccagcc agggacaatg
     4861 tggccctacc ttctccctgg agagacctca gctctctgga attcatctat atttagcagg
     4921 tggctggaca ggaggcagat aagcagagcc tggggagggg ggaggtcccc atatatagtg
     4981 ggaaggacag gaccccactc agtccctctt tgggtgacct gtgcctgctt cgtgcctggt
     5041 gtgacgtctc tcaggatgcc tgagccgggg aagaagccag gtagctttag gactggggtt
     5101 gggtctaagt gtgggagcag gggggtgtct acaattgggg agcagggcta ggagggagtt
     5161 cttgaggggg ttgacgagga cgtggcctct gagccccagg acaggggcag ccagtcctcc
     5221 agggtccttt tttgattctc ggtttctttt tcccatccct ctgatgagag gtgaaggtaa
     5281 acccaaggtc agggacgcag agaggggaca cagccaagac aggaagcacc cggggtcaac
     5341 ccattctgag aatgcaaagg gaccccttcc ctgtcccatt gccttcacct tccacagcaa
     5401 ggttccccgc ggacagagcc cacgtttagt atggagctga gccaggctca cggcatgcct
     5461 tcagaccagt ctctacccac tatgggtctc agtctcccaa cctggggtgc cgggggtggt
     5521 ggtggcattg ggttggttcc tcctggctgt gacattatct gcttcatgag cctgtacggt
     5581 gtggccccca tgttgagggt gacacagccc ctcttctctg agagaggaca gtcaggagcc
     5641 cctgaaccca ggccaagggc agggaaaatc acagcccagg gacctgggcc tgggctgtgc
     5701 ccttatgaag gttgtccagg gcagagatcc aggtccccat cccccagcgc cctcccaggc
     5761 cagctttatc tcagttgctg atacccagcc tgaggtcctt ggaggacaaa tttggccaca
     5821 ttccaagtag gcagacttcc ccgccccctg ccaagggccc gaaatggttg ggggaaaggg
     5881 agctgggttc atcacgggtg tctccaagca gggaaagtgg acacatgcag aaaaagtctt
     5941 gttgggaggt caggaccaca gccctggctc tcccgactgc tagctgtgtg atcttggagg
     6001 agccgcttag cttctctgag cctcagtgtc ctcctctgag aaatgaacag aataactgca
     6061 actacctcag agaactggta gagtattacg tgaggggatg catagaaagt gctagcacag
     6121 tatttactga gaggggctgc aggggcgggg tgcacgctcc aaccaggggc cgctgtagcc
     6181 tccacctggc ccttcagtct cagcttttag caagaagcca cggtcagtgg aagtggccgc
     6241 aggcagccct gccgtgttcg aggccgagac agagcgggca ggagtgaagg tgcgctggca
     6301 gcgcggaggc agtgacatca gcgccagcaa caagtacggc ctggccacag agggcacacg
     6361 gcatacgctg acagtgcggg aagtgggccc tgccgaccag ggatcttacg cagtcattgc
     6421 tggctcctcc aaggtcaagt tcgacctcaa ggtcatagag gcaggtaaga tcctgatcag
     6481 ccttccctga ggtttgggct gctgggggag gggcagccca gcgactctcc atccatccag
     6541 ggaacaggag gtgctttcac actttcttgc ctttgctgtg gctgtgcccc ccgccaggaa
     6601 cgccctttcc cccttttctg cacatgacct ctctgagtac ccccatgtgc catcctggct
     6661 tgttccagcc atggggtagg tgggagagat gaacaagaca caaccccact ctccccctgc
     6721 agacctccct ggggagatga ccctgcacag acggccggga agccccagga gctgtggatg
     6781 aggggagtgc agcccagtct gaggggctgc tctaaggctg gggcagagca gggatggacc
     6841 tggagctgtt cagggcagat gcagaggaca tgggaactga tggcctggga cggggaggag
     6901 aatgtgagag gcaggctggc tctccagctc agcatgagct gcctctgagg ggcccaggca
     6961 gcgggaggac agccatggca gactttcctc atccacagcg ggctcatggg tccaatgctc
     7021 aggagagaga gggtggaggg gtctctggtt agtggctgca ccacgactcc catctgatcc
     7081 cctccagaga aggcagagcc catgctggcc cctgcccctg cccctgctga ggccactgga
     7141 gcccctggag aagccccggc cccagccgct gagctgggag aaagtgcccc aagtcccaaa
     7201 ggtgagaggg gctgggcagg gaggggcagg atccgtgggt agggcgtgtc cagggcaggt
     7261 ctcaaaagcc tttgctgggc caggtgcggt ggctcaggcc tataatcccc agtactttgg
     7321 gaggccgagg tgggcggatc atgaggtcag gagattgaga ccatcctggc taacatgatg
     7381 aaaccccatc tctactaaaa atacaaaaaa attagccggg cgtggtggcg ggcacctgcg
     7441 gtcccagcta acttgggagg ctgaggcagg agaatggtgt gaacctggga ggcggagctt
     7501 gcagtgagcc gagattgtgc ctctgcactc cagcctgggt gacagagcaa gactccatct
     7561 caaacaaaca gaaaaagcct ttgctcacag ggtcaagctc agcagctctc aatggtccta
     7621 cccctggagc ccccgatgac cccattggcc tcttcgtgat gcggccacag gatggcgagg
     7681 tgaccgtggg tgagtgtgag ctgctgtgcc cagcattggg gtgggaaggg ggggcagcag
     7741 gacactcccc aagccgggcc tgtcgcccct gcctttgcag gtggcagcat caccttctca
     7801 gcccgcgtgg ccggcgccag cctcctgaag ccgcctgtgg tcaagtggtt caagggcaaa
     7861 tgggtggacc tgagcagcaa ggtgggccag cacctgcagc tgcacgacag ctacgaccgc
     7921 gccagcaagg tgggtccacc ggggtcgtgg agacacggag agaggggaca tggagagccc
     7981 tagaaggcac aaggcacaca gagggcacca tgagacccag aggcacacac gagctgcaag
     8041 caaggggtgt ggggaatctg ggaggcaggt ggaggggcca ggggcccaca gggagatccc
     8101 ggaggcctgg gggccaggga gtgcgatgag gctcatggga gcactgtcgg ggacctggga
     8161 gacttggtgg acatgatcac ctcaaggggg cacctaataa ggtttggccg ggggtggggg
     8221 gtcgcccagg gtggtcagga agcctggagg acactgtgaa gcatgggggc accagctagt
     8281 ggggttgtaa agcccctgga tgggtgagta tcagggctaa gggctcaagg gactctcagg
     8341 gattaaccag aacaattcct cattatacag acacggaaac caaagcttga gaggttaagt
     8401 ggctgctcca aggtcactta gacataggcc tagaacctta agccttcgtt ttttgtgttt
     8461 tgtttttttc cgccctgccc accagaacct taaggcttaa gtccccttgt ttgttcactc
     8521 caagcctctg cttttcccaa ccttccccag tcctgggcta ggcaaggggg cctctagcaa
     8581 gagaggccaa catgttctgc tgtgcggggc tgtgcattgc acaaaagcct gtatttcacc
     8641 acaaccatgt gccagcagat ggcaatcatg ggtttcgaga tagtcccctt tctctgtaca
     8701 aaaactctgt atgggttaac taaagcctga gggtgcgaag atcgatgagc atttgtcact
     8761 cccagcctcc tttaaatata tatatatata tataatttga gacagggtct cgctctgtcg
     8821 ctcaggctgg agtgcagtgg ctcaatctcg gctcactgca acctccacct cctgggttca
     8881 agcgattctc ccacctcagc ctcccgagta gctgaaacta gaggtgtgca ccaccatact
     8941 tggctaattt tcgttatttt tagtagagac ggaatttcac cacgttggcc aggctggtct
     9001 ggagctcctg gtcttatgtg atccgcccgc ctcagcctcc caaagtgggg attacaggcc
     9061 tgagccaccg cgcccggcca ctcccagtct cctttaaggg tgcggagcct tgtctcccgg
     9121 cccctggtgt cccctgacgc cccgtccctc catgcacaca ggtctatctg ttcgagctgc
     9181 acatcaccga tgcccagcct gccttcactg gcagctaccg ctgtgaggtg tccaccaagg
     9241 acaaatttga ctgctccaac ttcaatctca ctgtccacgg tgagggggcc ctggtgtctg
     9301 tcctgggctc gggctcccca tgggtcctgg tctcctacct ccttttccca acactaagga
     9361 ggatgcctcg tcccatccag acatgagtgc tggccacgtg cccagtgctg cacacacagg
     9421 gtgtgagaga aaccccaagg cttgcagggt aggcgtgggg gcttagggct gagtccgggt
     9481 ctcatctggg tgggactctg ttttatcatc ttggtgtcac ggctcctggc ccatggcctg
     9541 gcactgtctg aatgtttggg cgatgggtga aggtgagttg agagatgggt gggaattggg
     9601 gacaataaac cgtcccacct gcctggtacc ttgaccctgg gaaaggctgg gaaggtgaga
     9661 tcctggggca gatgcccagc ctcatggggt catgaatggg caagtctgtg aatactcaga
     9721 ggccgccccc agggcagggc ttctcaaacg gccccctctg aagccccttc ccccatctct
     9781 ccaccctttg aacccagagg ccatgggcac cggagacctg gacctcctat cagccttccg
     9841 ccgcacgtga gtggccatcc tcagggcctg ggggaggcca gtgctggagt ctgaggccct
     9901 tcagggtctc gactgggggt cagggctggg gatgatttgc ggggcggagc tgaagtcagt
     9961 gggggctgca ggggagagca agcttcccag gcaggtgagg atactgagtc taacccccac
    10021 aggagcctgg ctggaggtgg tcggcggatc aggtacccct gccccaggcc ctacctgcac
    10081 catccgcaga cccccagggg tctgagacgg gtgggagccc aatctggcta gtgtcccttt
    10141 ctccctcccc actccactcc catcctgctc ctaatccctt tccagtccct cactgcagcc
    10201 tcactggggg tccctctcca tagtgatagc catgaggaca ctgggattct ggacttcagc
    10261 tcactgctga aaaagaggtg agtcctgggt ggcagttcct ggggcagctg gtgaggcctg
    10321 gctccaaatc ccagcactgt ggtttgccag ctgtgtgacc ctgagcacaa cactgcacct
    10381 ctctgagttg gtttccttgt ctgtcgaggg gatgatccca gtgtggaagg agttaaaggg
    10441 ctctgcagac attatgtccc gtcaacagtc atcctcacag tgtcccccac ggccactcca
    10501 cacttgaggc tgcaaaagct ccctccgtaa actccgggga cccagaagga acagagagag
    10561 ggtccccaga gctgcagggt ctaccaggtc ggcccaactg acttatgttc tctctgccct
    10621 ctctctccct ctcccccggc ccctccatta tggctgctgc tgctgtggcc cagagagtaa
    10681 gaatcggggt ctgggtgttt gggggcggca gggcgctggt gggtgcagag gggattcccg
    10741 tcccctctct gagaggctgt ggtgagagac tcagagcagg gtgcggctcc ccacggacag
    10801 gggtgagtct ctgtgccttg ggcttctcct gccacccacc tatctgtcag agcttaggag
    10861 ggataagaaa aagtaatgca cacaggaggt cctgccagag cctccggagc agcatgggtg
    10921 ccccacaaca cagggagtgc aagtgcggaa aatagggagg aagtaaaggc ccatgggtgg
    10981 ggtccaggtc tttgagggaa ggtggccata cctctcatgt gccacctacc ctttctccca
    11041 cccccacccc tggagcagca gtttccggac cccgaggtga gtgcccaaca tagcacagca
    11101 ccctcatcac ccctaattct gccaggagcc cctccagatc cccagcccct cttcagctcc
    11161 cttggccccc agtcctgcct ggcctgggac ccagagcagc tccagctgcc ccaccagaag
    11221 ggaaggggca gagggacagg ggtggctaca gctccttggt cctgggccca ggaagccccg
    11281 cccagggggc tgcagtcttg cccccggcca cagcctagac tgcgggacac agggactcga
    11341 agctggaggc accagcagag gaggacgtgt gggagatcct acggcaggca cccccatctg
    11401 agtacgagcg catcgccttc cagtacggcg tcactgacct gcgcggcatg ctaaagaggc
    11461 tcaagggcat gaggcgcgat gagaagaaga gcacaggtta gcccttcctc agaggggaga
    11521 ggagagggca caggctagcc cttccctaca caggagagga gagggcatag gttagccctt
    11581 ccccacaggg gagaggagag ggcacaggtt agccccccac ctcgtccaca tacatggaaa
    11641 gagcggagtc cggcttagca cagagactca caggaaagaa gagcccaggt taacccctcc
    11701 ttgtgtagaa aaagccaaga atgcccaggt tagcccctta ccacagagat agaagagaag
    11761 agcaaaagtt aggccaggac agccacaagg aaaaggacag agctcaggtt aaccctcctc
    11821 accaaggaaa aatcaggcta cactttcttt ctctaccctc ttctgaaaag aaatgaagcc
    11881 cggttaaccc tctccacacc caaaagaaaa gggaagaggc ccgctaagcc tggagagcca
    11941 cacacaggca aagaaaagag cctggctaat ctttctctca ggcaaacaaa gcaggagggc
    12001 ttgggttaac taccctcacc cccaggcaga tggaaagagg agagcccagg aatagccctt
    12061 ctccactgag gggttgacaa gggcgggtgt gagccgggaa agcaggggtc tcacatgcct
    12121 tctccccacc atgtctgggt ctagcacagg gcctggcaca cacctcgagc gctctataaa
    12181 caccgactga atggaggggt cagcttccat gcaggatatg ggagacaagc ccctcccaaa
    12241 gcacacacac aaaacacaca cgatcatggg gacggggaga ggagctggtt agtccctccc
    12301 tgctgacctc ccccaggccc cttatccctc tgccctgcct ccctgttgtc tcagcctcac
    12361 tgggtttccc atcaccccat cgctaggtgg cctggccctt accggcaccg tggccccatt
    12421 taagccaggg atcccctgaa tgccaccaat gttcctctgg gttaactcct gaactgctga
    12481 gcccagaggg caccaagcaa aggactgtag gtgcccaagg aggaaaagat ggaggctggc
    12541 aaggcagatg gggacctccg agggtagggg tgtcttccag gaatagcaac aacagtaaaa
    12601 agagcaaatt gctggccagg tgcagtggct cacgcctgta atcccagcac tttgggaggc
    12661 cgaggcaggt ggatcacctg aggttaggcg ttcaagacca gcctgaccaa catggtgaaa
    12721 ccccgtctct actaaaaata caaaattacc tgggcatggt ggcaggcgcc tgtaatccca
    12781 gctactccgg aggctgaggc aggagaatca cttgaacccg ggaggcagag gttgcagtga
    12841 gtcaggattg tgccattgca ctccaacctg ggtgacagaa tgagactcca tctcaaaaaa
    12901 agtgagtgag ttccttccta agccagccac taggtgcttt atgtaattat ctcatttaat
    12961 tctcgaaaca acactatgat ggaaggacta ttaccatttc catgttactg aggaaaccga
    13021 ggcacagagg gtttaaggaa ctagcgcaag gtcacagagc acccagcagt agatctctgc
    13081 ccctccgcag ctgactccag gcccagccag agtatttgag gactcagggg tccttctctg
    13141 ctcggtggat ggagccccca cttcctccct gggctcagca gcagcaacat gggcttttac
    13201 aaacacggcc gcaagaggag gcattgttgt ggagcagggc tgggctcaag acccagctct
    13261 gccacacacc tgctgggctg gtggcattgg gccagtcgcc tctctgagcc ctatttcccc
    13321 cactgcagca gcatggggac caccgcactg gccctggggg ctgagatggg agtgagagtg
    13381 ctgggcacag agggctgcta ggtgggagcg cctgggaaga gtacacaact caggggttgc
    13441 tgagagaaga gaaggcacag ctgtcccagc cccagttctc ctgacaagct tctgtctttc
    13501 tggaagcccc taacccaatc cctgagctga gcaggtggag aggaccccaa ggaagacaga
    13561 aggacaaggt cagacagaca gagacaagga ggtgggttga cacatagaca cagataaaga
    13621 aatgaagaca ccatgcctgt aatcccagca ctttgggagg ctgaggcggg cgcatcacct
    13681 gaggtcagga tttcaagacc agcccggcca acatggtaaa accccgtctc tactaaaaat
    13741 acaaaaatta gctgggcgtg gtggcacatg cctgtaatcc cagctactcg ggaggccgag
    13801 gcaggagaat cacttgaacc tgggaggcag aggttgcagt gagccaagat ggcgccattg
    13861 cactccagcc tggccaacag agcaagactc tgtccaaaaa acaaacaaac agacaaacaa
    13921 acaaaacaaa aagaaataga gacacagaga agtggaagcg gggcggcaca gaggggattg
    13981 gaggggggga cctgggcccc agccacagcc acagtagctt ggcctggggg agcagggtgc
    14041 gggcggtggg gtggccgggg ctgaggggtg gtgctcagcc tttcagaaga agctggagcc
    14101 ggcctaccag gtgagcaaag gccacaagat ccggctgacc gtggaactgg ctgaccatga
    14161 cgctgaggtc aaatggctca agaatggcca ggagatccag atgagcggca ggtgcagcct
    14221 ggggtgggga ggggggctcg ggtggaggtg gggaccccca tagccttgcc tcctgcccct
    14281 ctccacatgc gtatctctga ctcggtgtgg ctctcagccc catctctctg ggcctaattt
    14341 cccatccttt tgctcctgcc ggtccctctc tctctctcct tttgtctcgg gctcacttcc
    14401 tcccgtcggg aacacttcaa cggccccttc tgttctacag caagtaagtt cccctctgga
    14461 tggcttgggg tggggggcac agggattatc atggggcgca ctgggcccgg aggggtgtcc
    14521 gcagctttcc tgccacttcc ctgcggcccc cacccaggta catctttgag tccatcggtg
    14581 ccaagcgtac cctgaccatc agccagtgct cattggcgga cgacgcagcc taccagtgcg
    14641 tggtgggtgg cgagaagtgt agcacggagc tctttgtgaa aggtgggcct gggacctgag
    14701 gatgtgggaa cctggggagg agatggcctc aggggagcca accctcatgc tcaccctgcc
    14761 tggacagagc cccctgtgct catcacgcgc cccttggagg accagctggt gatggtgggg
    14821 cagcgggtgg agtttgagtg tgaagtatcg gaggaggggg cgcaagtcaa atggtgagtt
    14881 ccagaagcac ggggcatggg tgttgggggc atctgcccag aagaggccac agcacttgcc
    14941 acccacccac ccggctaggc tgaaggacgg ggtggagctg acccgggagg agaccttcaa
    15001 ataccggttc aagaaggacg ggcagagaca ccacctgatc atcaacgagg ccatgctgga
    15061 ggacgcgggg cactatgcac tgtgcactag cgggggccag gcgctggctg agctcattgt
    15121 gcagggtgag cctggctggg ggggcacatg aggctttagg gcttggaccc ctcagccccc
    15181 accccaccta gccctgtagg ggagcaggca aacctgggct caaggcctct gtgaccttgg
    15241 gcctttgaca gcctaaacct catccttctc atctctaaaa tgacgatgct gaggtgaccg
    15301 ctccagaggg tactgagagg gtcatacggg cctggtgagc atcaccaccc ctcagacact
    15361 tgaggttcct tatgtgcact gcaccatcac aggcaaacat ggcacacaca ggcacacgtg
    15421 ttttcacatg cccacatgca cccagacacg tgcgcaccag cgcccatggg cccacacgcc
    15481 ctccacaggg attcacgcca cacccacaca ccctcccgag ctcaatggct ctgccctgcc
    15541 ctgcagaaaa gaagctggag gtgtaccaga gcatcgcaga cctgatggtg ggcgcaaagg
    15601 accaggcggt gttcaaatgt gaggtctcag atgagaatgt tcggggtgtg tggctgaaga
    15661 atgggaagga gctggtgccc gacagccgca taaaggtgtc ccacatcggg cggtgagtgt
    15721 gcagggcagg tggatgggac aggtggagac tgagatggag acagagagag acacagggag
    15781 aaacagagag agagagataa agacaggtgg acagagaggc agatgcacag agacaggaca
    15841 gagactgaga cagagaccca cagagaggga gaaacagaca gacccaaaaa gacaaagaga
    15901 cagaaagaca gaaatagttc tatagagaca gaaagatatg cacagggagg cacacacata
    15961 ggagagttcg tcagagacag agaagaacag agggacagag acaaagaggc agcagggaga
    16021 gacacggacg gggtcgagcg ctccccagca ccctccccca gcttgtgacc agggcagggc
    16081 aggaggccac caaggaggcc ggctctggcc agaggccctc actgcctctc ccgccctctt
    16141 gctcatccct ggagcaactg ggctggccgt gctgggccca agttcacaga gattaatgag
    16201 acccagcccc tgcccagtct ccaagggccc agccaaggag atgctttgat gtagaaatca
    16261 cttttacgct gcctacctct gaaggcacat taaaaagctg gaaaattaga taatatagaa
    16321 aaaaaaaggc atttttaaaa atcagaatac caacaagcca ggacaaggtg agggcctcct
    16381 gggaccctgg ctggggtatc tggcaaggcc aggggtgtgt ggcccagtgg ggtcccctga
    16441 gccactgctc ccctgcaggg tccacaaact gaccattgac gacgtcacac ctgccgacga
    16501 ggctgactac agctttgtgc ccgagggctt cgcctgcaac ctgtcagcca agctccactt
    16561 catgggtgag cctgctccag ggtagggtgg gtcggggcag tggggccagg agcccctgtc
    16621 actgggccct gcctttgccc ccgtgctact tgctcttcct tctcttgcag aggtcaagat
    16681 tgacttcgta cccaggcagg gtaagtcttg gggcccctga gtcttggttc tgctcacttt
    16741 cccgcaaccc acccacgcag gcctcccctc cactcacaga gggaagagca aggatcaaaa
    16801 gtgggggtcc tggggcccag cttcagcttt gccactcatg accatgggtc aattataatc
    16861 tctgtgagcc tcagtttcct cttctctaaa atgggaaccc tgatagtgcc acctcatagg
    16921 atagttataa agatgaggtg acatgatgta tcagacctgt caagtgctgt cacatgtgtg
    16981 actgttatta ttacatcttt tcttcttctt cctttttttt tatttttatt ttttttgaga
    17041 cggagtctcc ctctgtcgcc cacgctggag agaagtggcg cgatctcggc tcactgcaag
    17101 ctccgcctcc caggttcaca ccactctcct gcctcagcct cctgagtagc tgggactaca
    17161 ggcgcccgcc accatgccca gctaattatt ttttgtattt ttagtagaga cggggtttca
    17221 ccatgttagc caggatggtt tcgatctcct gatctcatga tctgcctgcc tcggcctccc
    17281 aaagtgctgg gattacaggc gtgagccact gcgtccagac tgctttgctt tgtttaactg
    17341 agggcagatt cctgatttat ttggccaggg aaccttttta atgtgtgcat gtgtgcgtgc
    17401 atgtgtgcgc gcgtgtgtgt gtgtgcatgt gtctgtgtgt gtatgtatat atgtgtgtct
    17461 gtgtctgtgt gtgtgcgtgt atgtatgtgt atttgtgtct gtgtgcatgt gtgtgtctgt
    17521 gtgtgcatgt gtgtatgtgt atgtgtgtct gtgtgtatgt gtatatgcgt gtgtgtgtgt
    17581 gtattgtgtg tgtgtgtatg tgtgtggcaa gacactgatg ttcccccagt tttcaaaatg
    17641 ctatgctagg tgacctgacc tgaatattac aagcctccca gccaacgtcc tggggtgatg
    17701 ggaatgttcc agatcttggt tggattaata attgcatggg tgtattcatc tgtcagaact
    17761 cagcctactg tcagatctga gcataaacta tacctcaata caaatctaaa aaaccaataa
    17821 ccaggggccc aggctcttga gcagccccgc cccagtgacc tgtgctcctc ctggctctcc
    17881 cgtttctctg aactacattg tgtcttctgc agaacctccc aagatccacc tggactgccc
    17941 aggccgcata ccagacacca ttgtggttgt agctggaaat aagctacgtc tggacgtccc
    18001 tatctctggg gaccctgctc ccactgtgat ctggcagaag gctatcacgc aggtactgtg
    18061 ggtccctcct cagtctcccc atctataaga tgggtgtgtg gaaccagcca agtgctagga
    18121 cctgctgcac accccaccca catgtgcacg ccctgctgtt ggctacccca tgggagagac
    18181 tggtcagggg gcaggcaagg tgggcagtgt gggtcagggg gtggaagaag cagcagaggg
    18241 gcgcttccag gctgagtcag ctcctctgct ccctacttcc ctcctgccct gttcccaggg
    18301 gaataaggcc ccagccaggc cagccccaga tgccccagag gacacaggtg acagcgatga
    18361 gtgggtgttt gacaagaagg tgagtgagac tgaggtcagg aggaggctcg tttgtctttc
    18421 atcactttct acctacgtgg tgccgagccc ttggcgaggt ctccatggag gtgccacact
    18481 tggccgggtg tgttgctgcc cccagcaggg tccctgtggg gccctcacac ctcaggcaga
    18541 gggtctctgt gaagtgtgct gatggccatc acaaggatgt ggacaccctc tcattgccag
    18601 gaagccctca tgactgggct gctccctggc tcccttcatc ctaagctgac cttgaccttg
    18661 accttgtgct ccctctcaac tcaggagtag tttctgagac acttttctgc cagtgtagct
    18721 gccggggtct tgctcctgcc tggcactgtt ggttcttctg aaggctgggg tcttgagggg
    18781 tcctcatgat agctcatctg agaggacagg tggttgcccc aggtcccgtg acaaagctag
    18841 aacccgagcc cctgccctca gtcggtgcca cagagatgat tttgaactag atgctgacgt
    18901 ggatgcagtc ttcccacagg ctgtgttccc cccatggacc cccgggacat ctggctgttg
    18961 gcggaggctg caagggcctc tggggtctga cttggatctc accccaactc tgcacccccc
    19021 cagctgctgt gtgagaccga gggccgggtc cgcgtggaga ccaccaagga ccgcagcatc
    19081 ttcacggtcg agggggcaga gaaggaagat gagggcgtct acacggtcac agtgaagaac
    19141 cctgtgggcg aggaccaggt caacctcaca gtcaaggtca tcggtgaggc cggccggggt
    19201 ccaagctgga gaacacagag gggcagcccc aaggagggcc catccgttcg ctcattcagc
    19261 cactcgacaa acatcacggg catgctccct gagccgagcg gcaacaggac aggtttttct
    19321 gcccaaaagg agccccgctc tgggggagat ggaggcagat gcatccagca gatttcctgc
    19381 gacactgctg tacatgagcc atgtccagag tgccgtggga gcactgagca gagagccatc
    19441 cctgtgcctg ggggtgatgc ctttaggagg ctgagaagat ggtgaggaaa ggcatcccag
    19501 gcagaggaaa ctgtgtacaa aggggtggag gagggaaagg gccttttggg tgtggagaat
    19561 gaatgaaaca tgtcaggaga ggactgggtg gggttgggag gatcagagcc aggacagggg
    19621 tgaatatggg cagtgagaag ccttaaaggg ttgacggagg gctggcgaca tgatcagaaa
    19681 tgcatcctgt tgagacccag cctggacaac acagtgagac tccatatcac taaaaaaaaa
    19741 aaaaaaaaaa ggaaaagaag aaagaaatgc attctagaaa gatctctttg gatctggggg
    19801 tggtgggggc agcctgtggc ggttagttgg agtgggaagg ggacgagcaa cgttactcaa
    19861 ggccctgagc ggggcagggc tgatgtgggt ccatcccacc ccatccagac gtgccagacg
    19921 cacctgcggc ccccaagatc agcaacgtgg gagaggactc ctgcacagta cagtgggagc
    19981 cgcctgccta cgatggcggg cagcccatcc tgggtgagtg caagggcacc ggatggaggt
    20041 gtgagggcgc caaacagatc cgagggaagg tggtgtgggg atgcctgggt tccagaccag
    20101 agctgccacc tcccctgagc caggctacat cctggagcgc aagaagaaga agagctaccg
    20161 gtggatgcgg ctgaacttcg acctgattca ggagctgagt catgaagcgc ggcgcatgat
    20221 cgagggcgtg gtgtacgaga tgcgcgtcta cgcggtcaac gccatcggca tgtccaggcc
    20281 cagccctgcc tcccagccct tcatgcctat cggtgagcct gcctggcctg gtcctgcccc
    20341 ccgccccctc cccagttaaa aacctccaat aatagcaggt gctctgcagg cagccatgct
    20401 agacactcac atccacagtc tcctttcatc ctcgactggg gatactcagc cgcattttac
    20461 agatgaggaa acaggctcca agcagttaaa tgacctgctt gagatctccc agctggttgg
    20521 ggtggagctg actctcacac tacgccgacc cctagttcac gtttcaagcc tctctttcca
    20581 tgtctacaaa atgggaataa tgacactgcc tatctcagag agctgttagg atgatatggg
    20641 atgaccaggc aggccatctg gcatctaaca ggtgctcaat aaatgttcat tgtcccctgt
    20701 tctccacacc cttcaaccca gggttttcac ctatgggatg gggcaagggc tgtagttagt
    20761 ggaggggtct caggggcatc tgtctgtgga aagagtcctg gaccaagact cagagatggc
    20821 agaggcagct ccatggtccc cggggggcca actggagtca tccctccctg aagcctcagc
    20881 ttcctcatct gtataatggg gtctgagtgg gcagaacagg tgttgagact gtggcagggc
    20941 tcaggaggac acctgttccc actagggtgg gtgagtccgg gggcagctgc ctgtggcaag
    21001 ggcaggccaa ggacccctgg gcccagggat ggggcacagc ttgggaagat ggcaggaatc
    21061 ggggcctgtg gggagaaggg tccaggcctc tcgttttagg gactgattcc tggtttgttc
    21121 agttcttagt caactcacct aatcatacgt gccaggaaat tcccatgttt tctgtagttt
    21181 tagttttagt tttttttttt tttttttttt tttgagatgg agtctcgctc tgtcacccag
    21241 actggagtgc agtcctggcg cgatctgggg tcactgtaac cttcacctcc caggttcaag
    21301 caattctccc acctcagcct tctgagtagc tgggattaca ggcatccacc accatgccca
    21361 gctaattttt gtatttttgt agagacggag tttcaccatg ttggccaggc tggtcttgaa
    21421 ctcctgacct caggtgatcc tcccacctcg gcctcccaaa gtgctgggat tacaggcgtg
    21481 agccaccgtg cctggctgct gttgctgttt gtttttaagc caatctacag acatgtcttg
    21541 taacagggac aaaatattcc ttaaagtggc caaaagccag ctgaacagga agtgccccct
    21601 atgtgaccag tgggcagttc agagtctagg gcatggatct ccagcttccc caggcttgct
    21661 cagacccctc tctgacctct cctctgccca ggtcccccca gcgaacccac ccacctggca
    21721 gtagaggacg tctctgacac cacggtctcc ctcaagtggc ggcccccaga gcgcgtggga
    21781 gcaggaggcc tggatggcta cagcgtggag tactgcccag agggctgtga gtgtccccgc
    21841 ccccaacccc cctccccaaa ggaagaacat gctcaccttg ccattgagca gattcacctg
    21901 tagtcaagtt ttttaggccc acttttgccg aaagttgagg acacccagag aaatatctgt
    21961 cctgttttca gaagtaaaaa agcttgccta gtgaaaaaca aatgcagagt aaagctgact
    22021 gtaacacttc tttgagcagt gcgaaatcag caactacatt ttaaaaacat atttaaggcc
    22081 aggcgcgatg gcttacgcct gtaatcccag cactttggga ggccaaggtg ggcggatcac
    22141 ctgaggtcgg gagttcgaga ccagtctgac caacgtggag aaaccccgtc tctactaaaa
    22201 atacaaaatt agccgggtgt ggtggtgggc acctgtgatc ccagctacgc gggaggctga
    22261 ggcaggagaa tcacttgaac tcgggaggca gaagttgcgg tgagccaaga tcatgccatt
    22321 gcactccagc ctgggagaca agagcgaaac tccatctcaa aaataaataa acaaataaaa
    22381 atttaaaaaa acatatttaa atcctggaga ttcctatcag aggagtgggc agtgggagtg
    22441 gggtgtcagt ggtgacacag cctgtggcct tgcctccccc tccccacccc caggctcaga
    22501 gtgggtggct gccctgcagg ggctgacaga gcacacatcg atactggtga aggacctgcc
    22561 cacgggggcc cggctgcttt tccgagtgcg ggcacacaat atggcagggc ctggagcccc
    22621 tgttaccacc acggagccgg tgacagtgca ggagatcctg cgtgagtgcc cctttgtgca
    22681 gtcacaagac ccgccattga caccccaggc ccttggtgtc cagtggaggt ggggacagtt
    22741 ggggaggccc agaatgctct gcccagaacg ctgggcagag acaggagggg ttggagccat
    22801 cgtccatgcg ctaggcctag ggaaaaagtg cagagagggt ggccaggcac agtggctcaa
    22861 gcctgtaatc ccagcacttt aggaggccaa ggcaggcaga tcacttgagg tcaggagttt
    22921 gagaccagcc tggccaacat agtgaaaccc tgtctctact aaaaatacaa aaactagcca
    22981 ggtgtggtgg cgcgtgcctg tagtccctca actacttggg aggctgaggc agaagaatcg
    23041 cttggacccg ggaggtggca gttgcaatga gctgagatca cactattgca ctccagtctg
    23101 ggtgacagag tgagacaacg tctcaaaaaa aaaaaaagtg cagaaagggc tctcttggtg
    23161 tatgtcagtc ccttagttct ggaacaggga aagtaaaagc cacagtaccc aagctctctt
    23221 ccaggagtgt ctcagctcca acaggtaaat attgtctatg tagtcagatt ggtccctctg
    23281 ggatccactt cccattcctt tgttccttgt cccaacaaag ggtccatctt ttgtaaggat
    23341 tggttctcaa agctggaacg aggcagcaaa ctcaggtggt aacaacacag ggcatagggt
    23401 gtcaaagccc aggcttacac cctggtctat gacttactag ctgtgtgact tcagtcaagt
    23461 tgcttaccct ctctgatccc tgccttttga agtggtgagg ctcggggaag ccagctgggc
    23521 ttgggcagcc tggagttgct gtgttagcag gagctaaagg aggcgcaggg cccagcaggc
    23581 agcttttttc ttagctgcag ctctctgggc cttgtctcaa gggaggttgg agctgtggag
    23641 cccctcagag ctgtggcggg ccctcactta gctacccact ctatacccac agaacggcca
    23701 cggcttcagc tgcccaggca cctgcgccag accattcaga agaaggtcgg ggagcctgtg
    23761 aaccttctca tccctttcca ggtgggactg gcccccttcc ctgtccccca ggggagagag
    23821 gctatagtgt gttgttccca tccagtggac tgatgtctca gggctggcct gatctgaggt
    23881 accagaggct ggggtggcgg ccggcccttg gagtgatcca ggttcagggt taagcttttc
    23941 ctcccctcag ggcaagcccc ggcctcaggt gacctggacc aaagaggggc agcccctggc
    24001 aggcgaggag gtgagcatcc gcaacagccc cacagacacc atcctgttca tccgggccgc
    24061 tcgccgcgtg cattcaggca cttaccaggt gacggtgcgc attgagaaca tggaggacaa
    24121 ggccacgctg gtgctgcagg ttgttggtgc gtggccaagg cctccttgag cccccttgtt
    24181 tcccttccct gggctgggct gctggggcca agggtggggc caggggaccc aacccacagc
    24241 tcacattttc cagtccactg ccccagcagg cctggccctg gttggcaggg gtggggtggt
    24301 ccctggagcc agtgaccccc tgctcactgt caggaggcgt ggtgacccaa ctgggtctgt
    24361 ctcccgcaga caagccaagt cctccccagg atctccgggt gactgacgcc tggggtctta
    24421 atgtggctct ggagtggaag ccaccccagg atgtcggcaa cacggagctc tgggggtaca
    24481 cagtgcagaa agccgacaag aagaccatgg tgagcccagg gtctggggtc cccacgtgca
    24541 ccctgcctag gcccggcaga cccaggccgc agctaccctt cactgtcctc accgtggacc
    24601 cctcaccctc cctctgctga tctgaatccc tccatagtag gggtggagat gccaagggca
    24661 cccaggagag gctctcggca tcaggaaggg cctggcccag agatgcctcc cctccctccc
    24721 tgcccccagg agtggttcac cgtcttggag cattaccgcc gcacccactg cgtggtgcca
    24781 gagctcatca ttggcaatgg ctactacttc cgcgtcttca gccagaatat ggttggcttt
    24841 agtgacagag cggccaccac caaggagccc gtctttatcc ccagaccagg tgctgtaccc
    24901 tcattcttcc aaccaggggc tggggcaggg aggctgtggg aacagggaga ggggcctagc
    24961 tttgtgtggc cctctcggta ccaagtcctg tcaccaacag gcatcaccta tgagccaccc
    25021 aactataagg ccctggactt ctccgaggcc ccaagcttca cccagcccct ggtgaaccgc
    25081 tcggtcatcg cgggctacac tgctatgctc tgctgtgctg tccggggtag ccccaaggta
    25141 gggaacttta ggcgctggtc caggccgacc aggaggcagg gctcacaggc cccgacgttg
    25201 agcagtcctc tccccagcct gtctcccctg ctttctctcc accttggggt gtatggaccg
    25261 ggttcctccc cctgggcagg gccatggtac tcactcttgg ttccatgttt gtttccagcc
    25321 ttgggcatag tcagggactc tcgtgggacc ccccgagtag aaacacagat gtgtctccct
    25381 gggtccctgc caggtcccct ctcagcctgg atggcttccc tccctctctt taccttattt
    25441 atagcccaag atttcctggt tcaagaatgg cctggacctg ggagaagacg cccgcttccg
    25501 catgttcagc aagcagggag tgttgactct ggagattaga aagccctgcc cctttgacgg
    25561 gggcatctat gtctgcaggg ccaccaactt acagggcgag gcacggtgtg agtgccgcct
    25621 ggaggtgcga ggtgaggagc cctcggggcc agggcctggg agatgggaag agcgggcggc
    25681 agtggggacc ctgggctttg ctccgttgtc ctcggccaag cacctgccct ggctgcaagg
    25741 gcacggaccc tgccacgccc agatgggcaa tagcttccag aaggctggga ggacacagtg
    25801 acatggcctc ctcttctgca gtgcctcagt gaccaggctg gctcctgggg atggccaggt
    25861 atgtaccacc cgacacccag ggcacaagtc agtggctgag ccctggccct tggtcctggg
    25921 gcagccatca gtaaatggga ggctgtaggg gccctccatt cactcgtaag ataacctgtg
    25981 ttgcaggtac aaccggatgc cagccccgtg ccaggagcct ggagggaagt tggggaaacc
    26041 cctccctact gttggatgta tgtgtgacaa gtgtgtctcc tgtgctgcga tgggggatca
    26101 gcagggcagt tgtcgggcag tcctgagtgg gtgttgcaca gactggtcca cagggctcct
    26161 gaaggaagcc cctggatctt tggggtaaaa ggagggtggc ctcaagaaac aatgtctggg
    26221 gacaggcctt tctggcctgc tatgtcttcc caatgtttat tgggcaataa aagataagtg
    26281 cagtcacaga gaactcactc ttctcaattt cggtgtgcct gttttcataa aaatgcacag
    26341 gggatggcca ggtgcggtgg ctcatgcctg ttatcccagc actttgggag gcggaggcgg
    26401 gccgatcacc tgaggtcagg agatcaagac cagcctggcc aacatggtga aaccccgtct
    26461 ctactaaaaa tacaaaaatt agctgggcaa ggtggcgcgc ctataatccc agctatttgg
    26521 aaggctgagg caggagaatc acctgaaccc aggaggtaga gtttgaggtg ggccgagatc
    26581 atgccactgc acttcagcct gggtgatgga gtgagaccat gtctcaaaaa aaaaaaaaga
    26641 aaaaagccca gggacattga tcttcacagc aaagtgagag cagatactgt tttttgtttt
    26701 gttttcccga tgattaaacc aggcccagag tggtttctga gttcataaaa cattaacgct
    26761 agaaggaacc tgtcttcccc tacagcattc actcttcaga tgatgaaact gagctgtgac
    26821 agcggaaagt gcatttaact ggtcccaggt gctcagcgtg atccttgtgc caggggccgt
    26881 ggtcacaacc gcctggaggt ggggtgaggc agaatctcag tgttgtgatt gtgctggggt
    26941 ggagctgcac taggtggctt tggagtccca gccagcaata agccagcagc gggttcagac
    27001 ccatatcccc ggtgggagac agcaacccaa tccagtccag gacgctgggc accagaaagg
    27061 tgtcagggcc agggccccac tctgctctca cttcccccat ggggagccta aatccgagca
    27121 tctgtttcct tttgggcgcg ggaagccagc aggtctcaaa ttccctgaga gtgcagccag
    27181 gtttttccag gacagaattc catgaaggca gctcctaggg gagcttctgg gagttctatg
    27241 cagtggaaga cactcctggc caggagtccg gggccctgtg ggaggccctg gctgaatcac
    27301 cacacctctc tcgaccatac ccacctgtaa gggaacggag agggccaggg ccttggcttt
    27361 ctttcactta atctcagttc aggtgaggac gcccagtctg gctgctccct ctagcagcct
    27421 gttcattcat ggcagcccag ctctctgcag ggccctcagg tgcccaggaa ggaaagctcc
    27481 tcccgcagcc ttgctctagg agcccagaac aggggagctg gggcctccgt gtgccaaagc
    27541 ttggacatgg atgacctcat ctccttcctt ccttccagcc tgaggtgact ttttagagtc
    27601 cagggatagc tttcctcagg cctgagccaa gaggaggtgt catttaacac aaggcagcca
    27661 gggagcctga agggagttga ggacatttat ttcacattca cacaactgta cattttctat
    27721 aaataatgtg gggctgaaat atttacagtc atttcttgcc catacccagg ctgtctctcc
    27781 ctcctgacac cccgtgcctg gagagacagc ctgcagacag atgtgcaaac ccagcttggt
    27841 ctttcctgcc ccctccctga tgctcaggca gagcagccag cggtccctgg gactccacta
    27901 gcctcgacca ctccatcctc tgatgccgaa ggcatggcag gccacaggga attcgccgct
    27961 ccactgcagt cacagaggct gtggcaggca gcagccaaca ctgcgggccc tgggcagtag
    28021 ctgccggctt gggaatgcag aaggaagcag ggaggctgcc actcactccg gctgcccccc
    28081 aattcttccc ttcctctctg tgcccttcct ctgagagggt gagccccagg gttccctcac
    28141 tcctcacaga gtgaaactgc tccaggcgcc cagtcatgcc gggtcacaga gaagggagag
    28201 ccagactctt gcagtggaca gttataacgc cagggacaag gacaaggaac cacaacacaa
    28261 atgtctcaag gacacaaaat agtgggttca caccggc
//

