LOCUS       NG_008692              32418 bp    DNA     linear   PRI 28-JUN-2009
DEFINITION  Homo sapiens lamin A/C (LMNA) on chromosome 1.
ACCESSION   NG_008692
VERSION     NG_008692.1  GI:209413717
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Johan den Dunnen. The reference sequence was
            derived from AL355388.30, AL356734.32 and AL135927.14.
            
            Summary: The nuclear lamina consists of a two-dimensional matrix of
            proteins located next to the inner nuclear membrane. The lamin
            family of proteins make up the matrix and are highly conserved in
            evolution. During mitosis, the lamina matrix is reversibly
            disassembled as the lamin proteins are phosphorylated. Lamin
            proteins are thought to be involved in nuclear stability, chromatin
            structure and gene expression. Vertebrate lamins consist of two
            types, A and B. Through alternate splicing, this gene encodes three
            type A lamin isoforms. Mutations in this gene lead to several
            diseases: Emery-Dreifuss muscular dystrophy, familial partial
            lipodystrophy, limb girdle muscular dystrophy, dilated
            cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford
            progeria syndrome. [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2114              AL355388.30        203350-205463
            2115-4643           AL356734.32        2001-4529
            4644-32418          AL135927.14        2001-29775
FEATURES             Location/Qualifiers
     source          1..32418
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.2-q21.3"
     gene            5001..30418
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /note="lamin A/C"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     mRNA            join(5001..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,27985..28074,28819..29088,29411..30418)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /product="lamin A/C"
                     /transcript_id="NM_170707.2"
                     /db_xref="GI:153281093"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     mRNA            join(5001..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,28819..29088,29411..30418)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /product="lamin A/C"
                     /transcript_id="NM_170708.2"
                     /db_xref="GI:153281094"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     mRNA            join(5001..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,27985..28197)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /product="lamin A/C"
                     /transcript_id="NM_005572.3"
                     /db_xref="GI:153281091"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     exon            5001..5605
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=1
     STS             5077..5425
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P1"
                     /db_xref="UniSTS:271604"
     CDS             join(5250..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,27985..28074,28819..29088,29411..29437)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /protein_id="NP_733821.1"
                     /db_xref="GI:27436946"
                     /db_xref="CCDS:CCDS1129.1"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     CDS             join(5250..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,28819..29088,29411..29437)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /note="isoform 3 is encoded by transcript variant 3"
                     /codon_start=1
                     /protein_id="NP_733822.1"
                     /db_xref="GI:27436948"
                     /db_xref="CCDS:CCDS1130.1"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     CDS             join(5250..5605,20948..21104,24734..24859,25136..25306,
                     25518..25643,26232..26452,26545..26767,27252..27359,
                     27444..27563,27985..28095)
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /protein_id="NP_005563.1"
                     /db_xref="GI:5031875"
                     /db_xref="CCDS:CCDS1131.1"
                     /db_xref="GeneID:4000"
                     /db_xref="HGNC:6636"
                     /db_xref="MIM:150330"
     STS             5319..5650
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P3"
                     /db_xref="UniSTS:271606"
     STS             5319..5425
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P2"
                     /db_xref="UniSTS:271605"
     exon            20948..21104
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=2
     STS             24690..24919
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P4"
                     /db_xref="UniSTS:271607"
     exon            24734..24859
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=3
     exon            25136..25306
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=4
     exon            25518..25643
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=5
     STS             26170..26529
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P5"
                     /db_xref="UniSTS:271608"
     exon            26232..26452
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=6
     exon            26545..26767
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=7
     exon            27252..27359
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=8
     exon            27444..27563
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=9
     STS             27790..28293
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="PMC169171P6"
                     /db_xref="UniSTS:271609"
     exon            27985..28197
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=10b
     exon            27985..28074
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=10a
     exon            28819..29088
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=11
     exon            29411..30418
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /inference="alignment:Splign"
                     /number=12
     STS             29700..29843
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="RH69068"
                     /db_xref="UniSTS:50685"
     STS             29730..29991
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="G15913"
                     /db_xref="UniSTS:8612"
     STS             29762..30620
                     /standard_name="LMNA_902"
                     /db_xref="UniSTS:277454"
     STS             30146..30262
                     /gene="LMNA"
                     /gene_synonym="CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL;
                     FPLD; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; PRO1"
                     /standard_name="D20S1027"
                     /db_xref="UniSTS:55344"
ORIGIN      
        1 tccaacccat gaggttgttg tatggaccca gttgagaatg tatgaaaaca tgcaacaact
       61 ataaagattg ttaaaatgta agttattcac tgtgtgagca ttattctgct aaatgtatgc
      121 atgtatgtat gtgtgtgtgt gtgtgtgtgc atatatatat atatatacac acacacatat
      181 atatgtaatt ttttttttga gacagggttt ctctcttgct caggctggag tgcagtagtg
      241 caatcacagc tcactgcagc cttgacctcc caagctcagg tgatcctccc atcttagcct
      301 cctgggtagc tgggactaga ggcatgtgcc accaccccca gctaattttt tttttaagag
      361 atggggtttc actatgttgg ccaggttggt cttgaactcc tgggctcaag caatctgcaa
      421 tctgcctgtc tcggactccc caagtattgg gattatgggt gtgagccacc atgctcagcc
      481 tctgctttat atttttattt ccatagctcc taccgtgttc taacaaacta taactttgtc
      541 tttggtttat tgactgtctc cctccactag aatgtcagct ccataagggt agggattttt
      601 gtctgtttta ttcacttctg catccctggt gtctagaata gttcctggta tatagtagat
      661 gttcaataaa tatttgttga atgaatgaat tctctgtgta taaggcagtt ctgtaaagcc
      721 cctaaatctt ccttctccaa gaagccctcc ttcaaatgta tgtaacctta tttagttatt
      781 gcacatcccc attttacaga tgatgaaact aacgctggaa aaacttgtcc agagtcactg
      841 acctgaaaag tggcagggcc agatgcattt gtttatccaa gaaaccctga gagggctggg
      901 catggtggct ggcacccgtg atcccagcac tttgggaggc tgaggtggga ggatcacttg
      961 actccaggag ttcaagacca acttggcaac atagtgagac ccccatctct taaaaaaata
     1021 aagaggctgg gtgcggtggc tcatgcctgt aatcccagca ctttgagagg ccaaggcagg
     1081 cagatcatct gaggtcagga gttcgagacc agcctggcca acatggggaa accctgtgtc
     1141 tactaaaaat ataaaaatta gccgggtgtg gtggtgggtg cctataatcc cagcaaccct
     1201 tgaggctgag gcaggcaaat cgcttgaaca tggaaggcag aggttgcagt gagccgagat
     1261 tgtgccactg cactccagcc tgggcaacag agcgagactc caactcaaaa aaaattagaa
     1321 acaccgagtg cctgctgtgt gccaggtgtt agggagacag atgaccaaga cttggtcctt
     1381 tctgtccctc acagcacttt caggaatggg ggtcacagag gaaacactag gatgctataa
     1441 gaacacagag gagccccccc acccaatcaa ggtcattggt cttcaagata aagtgcctag
     1501 gcctggtgca gtggctcatg cctgtaatct cacactttgg gaggctaagg tgagggggca
     1561 cttgaggtca ggagttcgag accagcctgg ccaacatggt gaaacctcat ctctactcaa
     1621 aatacaaaaa ttagccgggc gtggtggcac acgcctgtaa tcccagctac tcaggaggct
     1681 aaggcaggag aagcgcttga acctgggagg cagaggttgc agtgagctga gattgtactg
     1741 ttgcacttca gcctgggtga caagagcaaa actctgtctc aaaaaaaaaa aaaaaaaatt
     1801 ctcaaaccgt ccgttggacc caaccactgc atgctgattt cactcatgca tgctccagct
     1861 cccagacttc tgggatccct ttggaattca tccaattcag agtcctctac tgctctttaa
     1921 tcatttgtgc ttgttggttt tgcttctccc tctgtctttc ccactggtgg gaggctccct
     1981 tgggagcaag catagtattg ctatcaccct gtggcatagt gtgcagaact cttgcacacc
     2041 caggagctca gtccccgtct ttgatagcca ctctacccat actacaggta agaaaactga
     2101 ggtccagaga attcagtagc agatctagca tcactcagca gttaagaggt aggattagaa
     2161 tgtggtcacc ctctagccac cactcccatc acctctcacc tccagcaggc tcagctcctc
     2221 tggacctggc tgctgcttct gggttggtga tttttgccct ggcaaaggga gagcagactt
     2281 atgacatctg gagtccagag ttaggattga atattcagga taaagtttca ctttgaagtt
     2341 cagatttagg attgaggcca ttttgatggt ggtcgcaggg aacctttaga aagagcttgg
     2401 agtgaaattt ggggtgaaag ccctccttct ttctcctgca ccttttccac aagatgggga
     2461 ggtctggcca gacacagtgg ctcacaccta taatcccagc gctttggaag gctgaagtga
     2521 ggatcatttg gggccaggag ttttagacca aattgggcaa catagcaagg ctccgtctct
     2581 atcatgatag cctatagtct cagctactca ggaggctgag ataaaagaat cacttgaacc
     2641 caggaattca aggttgcagt gagctatgat cctgccaccg cactccagcc tgggcgacag
     2701 accaagattc tcaaaaaaag agcggggagg tctaggacag gaagggttaa gtgtggttta
     2761 gctttcccag cctggaaagg aagccaggcc aagcagctgg gtaggggaaa agggggcact
     2821 gagtgccagg gaggggctga ggcagtggga acagcatgaa cccttccctc acgtttcact
     2881 ggcttacccc tcctgcctct gcttctggtg tggagaagaa caagactttt tattgtctgg
     2941 gaagctgagg gtgggtgcca cgccctgggg gagagaagcc atattctggg ccccctcatc
     3001 cgggtgcatc cctagtgctc accatgctgc ccaggcaccc tcactgagat gagaactttc
     3061 cttgttcccc tcccctaata accaaagttc ctgccttaat cccactccag tccctcatcc
     3121 accccgaggc caggcttcag aacccagaac tgagggcctg tccagccctg ctttccttgt
     3181 gtttgaggga agccctgata tcttggagct gtacaaggta gcaacataat ttgatttccc
     3241 tggttgctca tcggaggata agctgtggga ggcagttggg cagggcatgc aggcagatgg
     3301 gacccaggcc tcaatgctgt cacctcttag agaggataag gtgggacggg catggtggct
     3361 cacatctgta atcccagaac tttgggaagc tgaggcaggc agattacctg aggtcgggag
     3421 tttgagacca gtttggccaa catggtgaaa ccccatctct actaaaaata aaaataaaaa
     3481 aaaaattagc tgggcttggt ggcaggtgcc tataatccca gctactcagg aggctgaggc
     3541 aggagaatct cttgaacccg ggaggtggag attgcaatga gctgagatca tgccactgca
     3601 ctccagcctg ggtgagagag caagacttaa tctcaaaaaa acaaacaaac aaacaaaaaa
     3661 aacaaacaaa cagaggatga ggtggatggt gggaccagga taggggccag gatgagggga
     3721 ggggagtgga aggcttatca aaagggtcct tggtgaggcc tgaggatgga ggctccagag
     3781 cctgaggtag cgaaccctgg ggacctgagt gatctcgttt tgtgagagag cctggcccct
     3841 ccccagagcc agctgcagaa tggacctggc cagagaggaa agtagagatg agtatggtgc
     3901 tggcctttgc agccagcaag gctgtggggt ctttgctgtt cctgtccccc actaccttct
     3961 tgccccccac taccttcttt ctggctgaaa ccaggataga gacccaatat tggctgtcca
     4021 gcccccagcc ctgcttcccc tttcaggccc ctctgggaac cacagaaatc tgggacctag
     4081 tgtcttggca acgtaatgaa tgcatgcaca gctctggtat ctgttttaaa ttatccatta
     4141 aaataagtac agttctgggg gaaaaaaata agttgactgg gtgcggtaag cagtagaaag
     4201 ggactgaagg gggaaggaac ccaggcagtg cttgggtcca aaggaagggg acaggagatg
     4261 gaaggggcag tgcctggctc ctattcttgg ctttctttag gggacttctt taggggactg
     4321 tggcttgttg cttgggtcta aaaacgaatg cttggctttg aagagagata gattggggca
     4381 aaagaaagaa aaaaagggac cccccaaact ccttgatccc tggccccaaa ctgggggcat
     4441 aaaggaactc aggttccaga actttgctcc ccccagggaa cccaggcatt ccttctccac
     4501 cccactcctg gcacactgag atgcagctct gaatgggctg cccacgtgtg gaggggggtt
     4561 ggggtgactc actattacta ctgggaggac agggggagcc agtggtggaa gaagggtgag
     4621 tcacactgat gggcaccagc ctcagccctc cccccacttt cctggctccc agccctgcct
     4681 acctgaccct ctcccttgct ttgcgcccac ttccctctct ttctccccga cccttttgcc
     4741 cacccactct ccctccttgg ctctgccctc tagcccagaa ggtctgaggc aatgggggca
     4801 agcttggagc cgacagtgct gagcaggcag gagccaagag aggggaagct tgagcctcac
     4861 gcagttaggg gtgcgctgga gagggtgggg cccgactccg ccacacccca acggtccttc
     4921 cccctcctca ccactcccgc ccccaccccc aatggatctg ggactgcccc tttaagagta
     4981 gtggcccctc ctcccttcag aggaggacct attagagcct ttgccccggc gtcggtgact
     5041 cagtgttcgc gggagcgccg cacctacacc agccaaccca gatcccgagg tccgacagcg
     5101 cccggcccag atccccacgc ctgccaggag caagccgaga gccagccggc cggcgcactc
     5161 cgactccgag cagtctctgt ccttcgaccc gagccccgcg ccctttccgg gacccctgcc
     5221 ccgcgggcag cgctgccaac ctgccggcca tggagacccc gtcccagcgg cgcgccaccc
     5281 gcagcggggc gcaggccagc tccactccgc tgtcgcccac ccgcatcacc cggctgcagg
     5341 agaaggagga cctgcaggag ctcaatgatc gcttggcggt ctacatcgac cgtgtgcgct
     5401 cgctggaaac ggagaacgca gggctgcgcc ttcgcatcac cgagtctgaa gaggtggtca
     5461 gccgcgaggt gtccggcatc aaggccgcct acgaggccga gctcggggat gcccgcaaga
     5521 cccttgactc agtagccaag gagcgcgccc gcctgcagct ggagctgagc aaagtgcgtg
     5581 aggagtttaa ggagctgaaa gcgcggtgag ttcgcccagg tggctgcgtg cctggcgggg
     5641 agtggagagg gcggcgggcc ggcgcccctg gccggccgca ggaagggagt gagagggcct
     5701 ggaggccgat aactttgcca tagtctcctc cctccccgga actgccccca gcgggtgact
     5761 ggcagtgtca aggggaattg tcaagacagg acagagaggg aagtggtggt ctctgggaga
     5821 gggtcgggga ggatataagg aatggtgggg gtatcaggga caagttgggg ctggggccgg
     5881 cctgaattcg gtcagattgg gatttgccaa ctatttggag ccggggggag gggcttgagc
     5941 aaaacagaac tagccctgcc agctcgaaga actctgggca cccaggacac atcggagtgg
     6001 cagaaagggt cctgttagaa ctttgttagc gggcttggca ctgtgctagc tttgcccaag
     6061 ctggctctga acacatgatg cccactaaga cataactctc aagttggcat ctgtccagcg
     6121 tgttggagcg aggtcaggaa ggcagggcaa tccccctttt ccctcccaag ggcttggcgg
     6181 tggccccccc tcagcatgac cttgtcctgg gttctaaggg ttgggaagtt ctccctcact
     6241 ctgccactct gcgtgtctgg gaccttcctt gggctctgac aggcccacca aaagagctcc
     6301 gggagatgag agatcggctc ccccgcagct cccacagccc ttggcctgct tggcccagga
     6361 atgcaaggga gggagggagg cagagggcag aggctcccag ctcaggaagt tgtgttatgc
     6421 ccaggtctgg ccgcactcct cccttggccc tctgcctagt gtcttcgagg gttgggggca
     6481 ctgtccttcc ctccttgggg tgagccactt tcattttccc agcggggcca ggcagtcttt
     6541 gctcgggccc atcctcttag ctgctgacgt tttgatcttt gtcttattga agtgctggaa
     6601 tacagtgaca tttttgaaat ccagccgttg gaagattcag gccactccca ctttacccac
     6661 ccctgcccca ccctacccca ccctactcaa ctgcaccttc ttcttttcta aaaaagcctt
     6721 tgggagcttg gaagtatagg ccctctcttc cagccccatc aaaatttgtt tcccttcttc
     6781 ctgccttccc tttctctatg cagacccagg ccaagagcac taagggtgct tggagatccg
     6841 taaagggctg ttggctttga cttcttctct ctcttttatc atctactcca aacttctgct
     6901 cttcctagaa ccctttgcta ggtgtggttt tgttgcccag gctggagtgc aatggcacaa
     6961 tctcggctca ctgcaacctc cgcctcccag gttcaagtga ttctcctgcc tcagcctccc
     7021 gaatagctga gattacaggc atgtgccacc atgccgggct aattttgtat ttctagtaga
     7081 gatggggttt ctccatgttc gtcaggctag tcttgaactc ccaacctcag gtgatccacc
     7141 cgcctcagcc tcccaaagtg ctaggattac aggcatgagc caccacgctg ggcccatcac
     7201 ccttctttct gaagagtcaa tggaagttgt gtgtaggaag acaggcttaa cggttttttt
     7261 ttgagacagg gtcttactct gtcacccaga ctggagtgaa gtggtgcgat cttggctcac
     7321 cacaacctct gcctcccagg ctcaaaagat tctcctgcct cagcctcctg agtagctggg
     7381 attataagtg tgtgccacca cacatggcta tttttttttt tttttttttt tttaattttt
     7441 agtagagatg gggtttcacc atgttggcta ggctggtctc aaactcctga cttcaaatga
     7501 tccacctgcc tcggcctccc aaagtgctgg gattacaggt gtgagctacc atgcccggcc
     7561 atcaaccttt attttgtttt tttgagacgg agtcttgctt tgttgcccag gctggagtac
     7621 agtagtgtga cctcaggtca ctgcaacctc tgcctcccag gttcaagcca tgctcctgcc
     7681 tcagcctccc aagtagctgg gactataggt gcctgccacc acgcccggct actttttata
     7741 tttttagtag agacggggtt tcaccatgtt ggccagggtg atctcgaact cctgacctca
     7801 agtgatctgc ctgcctcagc ctcccaaagt gttgggatta gagacgggag ccactgcgcc
     7861 tggcttcttt ttttcttgag atagggtttc actctgttac ccaggctgga gtgcagtggc
     7921 aaggtcatgg ctcactgcag cctctacctc tctggctcaa gccatcctcc cgcctcagcc
     7981 tcctgagtag ctgggaccac aggcaggcac caccacccac agctaatgtt tttgtattat
     8041 tttgtagaga tggggttttg ccatgttgcc cacagtcttg aactcctggg ttcattctgc
     8101 tgaaagagac cacacctgtc cttttcttta tttttattat atttttcaga gacagggcct
     8161 tgccctgttg ctcaggctag agtgcaatgg tacaatcata acttgctgca gcctggaact
     8221 cctcctgggc tcaagcgatc ctaccgtctc accttccgga atagctgaga ctaagggcag
     8281 gcaccaccac gcttggctaa tttttttttt tttttttttt tttttgcttt ttgtttgtaa
     8341 agatggaaac ttgctatgtt gctcagctgg ttccgaagtt ttggcctcaa gcaatcctcc
     8401 tgcctcggcc tccggaagca ctgggattac aggcataagc caccaggcct gacgccaggc
     8461 ctgtcttttt tctactagtg atatgaacaa tttagttagc aagacagata ggaagcaagg
     8521 aaggggagac ccagagaatt cgttgcattc taaactagtc cactcatcta ccaaagccct
     8581 gtgaaggaca tttttagcag ttttagcagt tttctggtca aaactttgat cgagaaacag
     8641 attgagtgga ttcgatattc tcttgctcac ccagccacgc cagtttgtct cctctgcctc
     8701 ctagtgcagc tgtccaggcc tgggacacca ggcgggtatg tgcgcatgtg gggcagggcg
     8761 gaggtggtgt gtgtacttgt tatatttagc cacctccctc tgttctcccc cactgatcct
     8821 ggctggaaag gctgggcttc cggaaaagag aggtggattt gcacacctgg atcccaagct
     8881 gatagaaagt ggggtgaaga caaaggggac tcagactggg gtgtctgtcc tcttctatgc
     8941 ccacagtagg aggagccagg attggttact ccctgctggg tctgctgtgc tcagagtgag
     9001 gtagagaagt gggtagagta aagaatttgg gagaggaaaa aaggcatttt cccaacccct
     9061 cccaccaaag cctagagaga aggtgttgtc tggtttaatg tttaattaga gctcagagtt
     9121 cagggccaga tttggagttg ggatggaaag ttgtttttaa gaccctgtag caatttttga
     9181 cccagcctgg gtacctcaac cacactcagg agtttggggg accttctgtt gggctggatt
     9241 ataggctcca agaagaaacc cctttcgcca atactctctc tctcttcttt ttttgagaca
     9301 gggtcttgtt ctgttgccca ggctggggtg cagtggcatg atcacagctc actgcaacgt
     9361 cagcctcaca ggctctggtg attctcccac ctcagcctcc tgagtagctg ggattacaag
     9421 tgtgtgccac catgcccagc taattttttt tttctttttt tttttttgag acggagtctt
     9481 gttctgttgc caggctggag tgcagtggtg cgatctcggc tcattgcaac ctccacctcc
     9541 caggttcaag cgattctcct gcctcagcct cccgagtagc tgggactaca ggcacatgcc
     9601 atcacgccca gttaattttt gtatttttag tagagttggg gtttcaccat gttggccagg
     9661 atggtcttga tctcttgacc tcgtgatccg tccaccttgg cctcccaaag tgctgggatt
     9721 acaggtgtga gccaccgtac ccggccacta atttttatat attttgtaga gatggggttt
     9781 caccgtgttg cccaagctgg tctcgaactc ctaggctcaa gtaatccacc tgccttggcc
     9841 ttggcctccc aaagtgctgg gatgtatagg catgagctac cgcacctggt accccctgcc
     9901 ccttctctgt ctctttctag tctgtagccc aagggatttg gatacccaag tgcaggcaga
     9961 atgggaaggt tgtaagcacc agggaagcct gtctggagtc caggcttgca gctgggcccc
    10021 accccaggca aggcagctgg gtggatgact cagatgctgc ccccctccct cccaccctgg
    10081 tggctttaca gaagacagca ggagacaggg tggagacagc agttgtctta aagggaggag
    10141 tggtggtctg aatgtctacc tcttctgccc ccctccccat tgcatcctgg agtcccttgc
    10201 ctggctcctt cctgagaccc tctggtggtg tctggacaca tagctctctc tggacaggta
    10261 acatgcacaa gtaattagaa tccagagttg agttcagagt tatggattgg gctgcaggat
    10321 agtgccaggg tctgtgcctt cccatgtgaa actgatggag gaaggctgag tcagaagtgg
    10381 ggagatccga ggcccacaaa gcagaagcgc tacttccact ccaaaaaggc cctggtgctt
    10441 gacaacttcc tggattgccc actgttgcag ccccagtgtg gacaggcagg gagatgcagg
    10501 ctccagttca tgtaggctct gatcaagaca agaacagcaa aggccacaga ggcacagatg
    10561 cttgtcccat gtcacacaat aaaggggtca gcacttgatc acaggcctta tgacttccag
    10621 ctgggtgtgc tcttaccatt aagcctcact tctctagctt gggggacagg ttggagggag
    10681 gatctagagg gtgaggtaag gtgaagtcag gtagctgagg ctcacttctg cagcctggaa
    10741 actctgctct ggggccagtg acaccttagt gctctatggc catacttcgt ggctcatgcc
    10801 tgtaatccca gtgctttggg aggctaaggc aggaggatca cttgaggcca ggagtttgag
    10861 accagtctgg gcaacatagc aagaccccct tctgtacaaa aaaattagcc ggtcaacacc
    10921 tgtagtccag ctgcttggga agctgaggcg ggaggatcac ctgaagccag gagtttgagg
    10981 ctattgtgag ctatgactgc actactgcac tctagcctgg gagagagaaa gaccctgtct
    11041 ctgaaaaaga aaaaaacaaa acaaaactct gctgtcctgc agggcctgtt agcatatgat
    11101 cgatagcctt tgctccagcc tatacctgga cccaggaccc ctgccagccc ctcaatcgtg
    11161 agacggtcag agctctggga ggctggtgat tcttgtcttg agactatctt gagacttgtc
    11221 atgggaattg tccacccgga ttgaaaggaa gctgtgcctt ttggcagacc cattaggtta
    11281 atggggttgg agacctttga ggatgcatgg gccctgggct ttatctgagg gtatctcctg
    11341 gtgttacctc tccaaccctc caccaccaaa tccattcttt tttttttttt tttttttttt
    11401 ttgacagtct cgctccctgg cccaggctgg agtgcagtgg catgatcttg gcttactgca
    11461 atctccacct cccaggctca agtgatcctc ccacctcagc ctcccaagaa gctgggacta
    11521 taggcacgtg ccacatgctc ggctaatttt tctattttta gtagagacca ggtttcacca
    11581 tgttactcag gctggtcttg aactctgggg cttaagcagt ccacccacct tgacctccca
    11641 aagtgctgag agccactgag cctagcccaa atccacgttc tgattcaaag ggaaagaaga
    11701 agggtgcagc taaacctggg gggtgagaag tacttaaaaa gcccaagaga aacaaaagag
    11761 agaataattc ctcactagga ccccctattg ccttcccact attggtgccc ttgcttggca
    11821 cttcccctgg cctccaggag tctgagactt actcttccat ggatgtgccc attgccccca
    11881 cttccaggtc caccccccag tgattcggta gcttagtgtc tgcgctgaag cccaggacag
    11941 ctggatggac aactggtaga tcccttcacc taccaactgt gctttctgct cccctccccc
    12001 ttgcttccct cctccccagc ccctcgccac ccctagcagc tgcagcagcc aagaccaagt
    12061 cttcagagac ccagacacaa gggcagggtt cattccattc tcacctcctt ggggtcccag
    12121 tgtactgata ggccgaactc taatattata ggagatctct ggaagattgc agggtctctt
    12181 atccctcaat aaggggcaag gcaagccggg cgcagtggct cacgcctgta atcccagcac
    12241 tttgagaagc cgaggggaac agatcacttc aggtcaggag ttaagagacc agcctggcca
    12301 acatggtgaa accctgtctc tactaaaaat acaaaaatta accagaaatc gcttgaaccc
    12361 aggaggcaga tgttgcagtg agccgagatc acgccactgc actccagcca gggcgacaga
    12421 gcaagattcc gtctcaaaaa aataatacta ataataaata aataaataag gggcaaggta
    12481 gtccaccaac aaaatgacag gcagtgtgat atagtggaca ccctagccct cggtgccctt
    12541 agttctgtgt gtggcccttt cactaaattg ctgtgtgacc ttgagcaaat cgcctcccct
    12601 ttctggcttt ccttagctgt aaaagaaagg gattggagcg gaaagtctcc agagaccttt
    12661 taggttccaa agtagtacag tgacccacaa agtgagaaaa cagtcttcta aaataccaag
    12721 ttattaatag taaaatcaaa tataaataat gtgaatatag ttaatagcta atgttgttct
    12781 caatagaaat gtttcccaca agctgtggaa ttaaacatac taccacattt ctctatttcc
    12841 ccgtgaaagt ttgttagaaa tggttaaatt gtgacattac cctcttggca aatgttttgt
    12901 tttcattgct actaggaaag ggcaactcgt tttcgatgcc tctcccttct ggacggtgga
    12961 aagggctgtg tcatagagta ggaacgggag atgcggcaca ggaatggctc ccattgaccc
    13021 gggttggggg ctagggcgaa ggcctaggag aggcagaact gttaccttag agctggccag
    13081 gattagagaa cagtgcctgg aaccgggggg aggggcacgg tgaccttggg ctgcccacct
    13141 tctacccttc cagcacccat actggctccc ccaacctgcg gctgggctgg gaggaggtct
    13201 tggcccctac caatccctta aggaagggga aagagtttgg gaaggggagt cctcccttca
    13261 cccctgcctc ccccaagttg tgagagagga agccggaatc ctgcctgctg aagccaggaa
    13321 taattctggc tgagatccca ggcccggcag gggcgctgag tcatggtaga gggcagagtg
    13381 gagagtggac aggagaccct aagcttgtcc agtcagaaaa gcagaggctg aggggtggcc
    13441 ttttcttgag aactacattc aagttgcagc aagaaggaca gtggtctgaa tttgacgggg
    13501 acaaatggaa gggagatagg acacatgagt tcctttaggt ctggctcagg ggagctagac
    13561 ttcatttcaa ggggtctagg ttctgggcag ttgagaagga ggctatttgg ggtcaccaag
    13621 gctccccttt cttcccaaag ctctaacact gccaccttct gctggctagg agagagctgt
    13681 gtcttctgag gctagagctg gaatgcagtg agaccagact gcctaggtcc tccctcactt
    13741 cttctcctga ccttggggtg tggctcccac tctctcccag tgtcctcagg gttaataact
    13801 atgtgccacc agatagagag ttaaggggct gctgaattgg cttcttgtga agggaatccc
    13861 ctaaatgtcc ctcgttttgg tcactggcct ccctcccgcc cccttcagga cattctacta
    13921 tcttcttagg ccatccctcc ctcctccagg cactacttct tttgctctat ccccaagccc
    13981 cacccctgca tttttgtgac aacaccggaa tgatttctag agagagaggc caggaagaag
    14041 gaaagtggca cttggcagga gaccttgcag ggggcggctg gtgaggaagc cagccgccca
    14101 ttgtccagga ccccagtgcc ctggcctccg gcctcaggct tctcctgcct ctgtacaatg
    14161 ccacgttgat acgcccagca gctgtgactc aggcctggcc ccctgccagg cccagcactt
    14221 ctactggagt tgcgtctgaa catgtcaaca ggcttcctat ccctctctca gcaccagttc
    14281 tccccacttc agcccctccc tctgcctgga attaaaacct ggctttgtct tagggaagga
    14341 cagctgggag cctagtggct ctggtagggg atctgagagg cctcagaccc taggcatatt
    14401 tggctgtttg gcaggtgtca cgcccaaggg aagcgtgtgg aagcagagcc atgcctgctg
    14461 tgggtgcaca tgcccgcgtg agggagtcgg ggtgtttcat cctggggcac ctgtgggctt
    14521 ttgaggtgta tgatattcag aacttcacag gttggggttt ggggaaggct caaggggctt
    14581 ctaagtccct ggaacagctg cccccctcag ttcctctctc tctctctctt tttttttgag
    14641 atggagtctc gctctgttgc ccaggctaga atgcagtggc gcgatcttgg ctcactgcaa
    14701 actccgcctc ctgggttcaa gtgattctcc tgcctcagcc tcccaagtag ctgggactat
    14761 aggtgcccgc caccatgcct ggctaatttt tgtattttta gtagaaatgg ggtttcacca
    14821 tgctggccag gatggtctca aactcctgac ctcgtgatcc acccaccttg gcctcccaaa
    14881 gtgctgggat tacaggcgtg agccactgcg cccagcctca gttcctctct ttaaggtctc
    14941 ctttccagag agggatagca cctcaaatgc cagggagggg aattctccac atcctgccct
    15001 tacccgagtt gtggcagacc cacagactag ccaagaaacc aagcagtggt tactttgccg
    15061 ggttgggggg gaggtagggg ctatcaaacc tcatgattgg ccgcacacaa aggtgtgagt
    15121 atgtgtatat ttgagggtgg gtgggagtgg cactttcact aggcctccgt atcactctct
    15181 gactggggta tctcccagca agcgagacag aggcagacac gcttcccaga ctgtcttact
    15241 gggtctctct gtgttattct ctgcagtgtc tgtgtgtatc gtgccatttt ctatgttttg
    15301 caccaatctg ctgtgagtgt cctcaggtga cctgggggca ggtttttagt gcctgagcct
    15361 acccgtctcc aggctttagt ttccccctgt aaaagtatag gagttggttc aagagaaggt
    15421 tcctctagaa gccttgagcc tgtgaaccgt ctagtctccg ggtatttgtg ggacacacag
    15481 aaaaagcccc acgacccaac aggtagaaca ctggctgaaa tcagcagggc agagctgaga
    15541 caggctcaag taggctgagg ggtagggagg ttttgggtga atgggaggga gggacagaga
    15601 gaaggaggat atattgcagt aggaggagtt gctggaacaa aaggaggggt ggtaggagtg
    15661 gcttggggtg gcagcagaag acgccctgtc acatggcggg aagtcagcct gggcagaggt
    15721 ctaggtgtcc aggaggggct gggtgtggtg gctcacgcct gtaatcccag gactttggga
    15781 ggctgatgca ggaggatcac gtgaggtcag gagttcaaga ccagcctggc caacatggcg
    15841 aaaccctatc tctactaaaa atgccaaaaa ttagctgggt gtggtggcag gcgcctgtaa
    15901 tcccagctac tctggaggct gaggcacaag aattgcttga acctgggagg tggaggttgc
    15961 agggagccga gatcgcgcca ctctactcta gcctgggcaa cacagtgaga ctctgtctca
    16021 aaaataataa taataggggc tgggcgcggt ggctcatgac tgtaatccca gcattttggg
    16081 aggtggaggc gggtggatca cctgaggtca ggagtccgag accagcctgg ccaacatggc
    16141 aaaactccgt ctctactaaa aatagaaaaa ttagctaggc atggtggtgc aggcctgtaa
    16201 tccagctact cgggaggctg agaagcagga gaatcacttg aacctgggag gtgaaggttg
    16261 cagtgagatc acctgggcga cagaatgaga ctccacctca aaataataat aatagtaata
    16321 ataataaatg aaaaatttta aaattaaaca attaaaaatt ttaaattaaa attaaacaaa
    16381 ttagatgccc aggaggatac aggagagcat ttgccaccag gcggactccc tgtacccacc
    16441 cggccacagg gggcgatgtt cctgggagac aggaaatgcc caggggctgg gagaccctct
    16501 gctcttctgc tcccttcctg tgtgctgcct ggcaatgggg aactctgagg gctggtgagc
    16561 agggctgctg aggagtgggt ctaaggagtc cctgcagggc tgggccagct cctccacctc
    16621 ccctttgtct tcccctccca cttgttattt ttagctacag tgtctgtccc tcttgcttct
    16681 cccccagatt gggagaggaa acggaggcct ctccctccgg gcctagcctg ttgcccccag
    16741 caaccgggcc caaacaggcc tgtggccggc cctggcttcc atatctggca tcagagttgg
    16801 gctgagcagg gtgactcaga gggtgggtca gcgcctggcc cggtgcccac ctagcccctt
    16861 tgctgtgctg gtgcctttct tccccaaaca gccccaaggg cccgggcctg ctgcagctgg
    16921 ggagccggac ttccttgtcc caccaggcac agctcttcag acccctgcct tgggtcacat
    16981 ttgcaagtgc caactctcat ttctacctta ttcttttcct ctctgttccc ctccccaccc
    17041 cctctcttcc ctctttctga gatcagattt gccagtgatg ggaagagtta gaaacaggat
    17101 gcccagccct tctcgcctca agaggccact gggatgcagc cactcctgtg cttggggaac
    17161 ctggaggatg caagggaaag gactggcact ctgctggcac agcacccggc ctggggcagg
    17221 acacgggcga agccagggtc tcccctgtga gcactagagg atttcccgac ccctgcccgg
    17281 gtattgtgtg cctgagcatg agtcacctga ggggcccagg ttcccaccct tcccagctcc
    17341 tctggcctgc cccaccctgt cctccctgcc aacccagcac ggggacggca ctcagcgtgt
    17401 gctcagcttt cctgatgcca acccccagtg gagtgggctg caccaccacc ctgggaccga
    17461 atgcctggct agggtctact ttggtccctg ctaggtctga ggacccctcc taggaaggaa
    17521 atggcacttg ggggcggggg cagggaggag ggaggagaga cactgggctc tactgtaccc
    17581 ctagtcatct cttggggtgt gcgtgtggct ccctggccac agagctccca aggtctgagt
    17641 catgagccca tgggtgatag tggcttcttc cccgcagatg ggagctcccc gtgcctaaga
    17701 aaaccacaaa ggttcttcct cacttccctc tctgctcgtg gtttttctca tctgcagggt
    17761 gtgtcttagt cctttaatct cctctctttg cagtgctagt caaaacctcc accagggaaa
    17821 gacaaataac ccccttactg tttttttttt tttttttttt tttttttgag atggagtctc
    17881 gctctgtcac ccatgctgta gtgcagtggc acaatctcgg ctcactgcaa cctccgcctc
    17941 ccaagttcaa gtgatcctcc tacctcagcc tcctcagtag ctgggactac aggtgcacac
    18001 caccgtaccc agctaaattt tttttttttt tttttgagat agagtctcac tctgtcaccc
    18061 aggctggagt acagtggtac aatctcaact cactacaatc tccgcctccc aggctcaagc
    18121 aattctcgtg tctcagcctc ccaagttgct gggactatgg acgtgcacca ccttgcccga
    18181 ctaatttttg tatttttgat agagtcagag tttcaccatg ttggcaggct ggtctcgaac
    18241 tcctggcctc aagtgatcca cctgccttgg cctcccaaag tgctgggatt acaggtgtga
    18301 gccaccacac tcagccagcc cccttacttt ccttggagac catatactgt ggcttgtgcc
    18361 aaagtggtac agcatggatt tccagctccc ctatctactt gctgcgggac cctagatata
    18421 gctttctgtg cctatttcct caattgcata ggaatagcac ctatcgcata gggtagctgt
    18481 gaagatgacg tgagttaaca taatatttag agcagtgctt ggtacctaat aagctctata
    18541 taagtgtttg ctattatatt attattatca ctgccaccac cgcttttgca agcagcagaa
    18601 ggtgaagagg ttagactgaa gaaaaaactt ctgtgctcat cagcccataa gctcgcagag
    18661 cacagggatc atgcatctat gttttcctca gtcagtgtct gccaggcact ggcaaggaaa
    18721 ggctgttacc agggggaact ccaggaattc ctcctggcac ctaaggaggc tggggagaca
    18781 ggactaggga aaaggtgccc ttgagacacc ttctgaaatc atcccattgc cttccagctt
    18841 ctttcagctc aggctggctg gtcagggaaa cgctttgtgc catagtgtct gccctcttcc
    18901 tcctcctggc ttctccattc tctctggaac ttgtggctta ggaaagcagt gaggtggagg
    18961 aggaggaacc ctagatcagc agctagaatt gactggaatg ctgctgctgg ctttcggtaa
    19021 ttgacactgg gccattcacc ttcctccttt gcacctcagt ttcctcatct ataaaaggga
    19081 gagggttgag ctgaatcaac tctaagctcc ttctagttct ctaaattctg agagcctcct
    19141 agtacagcca gcagcagcca ttagccttca gggtagagag gcctcttctg ggaagcccca
    19201 gccagcctgg gggtcagccc aaggagctcg gaatctaagt tgccccagtt gcttcacttt
    19261 accagcggtt tttcttcatt ttccctcctc cccctgcagc tgcttcagct tcggaaaagt
    19321 tctgaagtca tggaaagttg gggctgtgct cccagccagg ggctaggccg gatggcagcc
    19381 aaaacctgag ctgggttttg actttatttt tagcttttct gactgagaca gaggagggaa
    19441 tacattctcc ggttctggaa ggggctcttt tttgcaggag acagacactt acattaaaca
    19501 acttgttctg aggtgtggcc agaggcctgg actgagcaag tgtgcaggct gggggagctt
    19561 cctctggctt ctcatgtcct tcccctgccc ctctgagtgt cactctatcc tcctccctgc
    19621 ctggtggggg gaggtggggg tgactccttt tttggactct cctaagcaga acactgcctg
    19681 ggtctcgtcc tccagagctt ctgcaaatct agccttccct atccctcttc acagtgaatt
    19741 gctgggcctc ttggagttta ggacttttgt ggtagaagaa aaatgttggc agggctgctt
    19801 ttctcctttc caggatagat ttttccttct gcccacgctt ggttttcctt ttttccatct
    19861 gctgtggtgg gctcatgctt aagcactgat gagttacaga tggcagctgg aaccaggtcc
    19921 tctggatctt tccctccgct ccctgggtct gctgctttct ctcaccctat atttgtgaag
    19981 caattgtaac atctagaaag ttcttgggtt ctctggaggt ttttaagaaa ataggacctt
    20041 tctatttctc cagtccacta gcaaaaataa tcaggggccc agaaaaggtg agggaggtgg
    20101 cagaggcagc gctgttcgac tggttatagc taaagcttta cccactttga ggagcaggga
    20161 ggcttaaagc tggggcccag atggacctgg aggcctggga tccacatctg gaaccagatg
    20221 ctgaggctat ggtagatggg tagggctcag ccttctccca gggcacggat gaggcaggag
    20281 ggagggaggc agggacccct ctgttcagtg cagatcaggg cacccagact gggtcctgag
    20341 aaaggaaagg gtcaatattg tgcctggtca tccttgtctg aggtccctct gagctctaac
    20401 cagactttcc ttccccacag tcccacatgt gtaaaaggga ctaggagagg tgaccagtac
    20461 ctttggggct cagatcgaga agtgctaggg acatgtgggc catgagctta gttgtcaggc
    20521 tcctcagagg gagggaagct tggccaaagg gaagtgagta gagtccaggg agaaggctaa
    20581 gtaaggccct gtgtgggaag gggcaggaga caaaggtacc cctgtctctt tgggaaagaa
    20641 tgggaggaga gagagggaaa agcattcata tcacggggta gagctctgcc cttggcccca
    20701 ggcacgttcc tgagccctga gtcatgggaa gggtggagaa gcaggaaggg ggttttcaag
    20761 gaccttgggg aggtgggagc ccagccccag aggcaagcag atgcaaacca acctaatgca
    20821 aggatgccct ctcctggtaa ttgcaggcat agcagcgcca gcccccatgg ctgacctcct
    20881 gggagcctgg cactgtctag gcacacagac tccttctctt aaatctactc tcccctctct
    20941 tctttagcaa taccaagaag gagggtgacc tgatagctgc tcaggctcgg ctgaaggacc
    21001 tggaggctct gctgaactcc aaggaggccg cactgagcac tgctctcagt gagaagcgca
    21061 cgctggaggg cgagctgcat gatctgcggg gccaggtggc caaggtgagg ccaccctgca
    21121 gggcccaccc atggccccac ctaacacatg tacactcact cttctaccta ggccctcccc
    21181 catgtggtgc ctggtctgac ctgtcacctg atttcagagc cattcacctg tcctagagtc
    21241 attttaccca ctgaggtcac atcttatcct aatttggctg ccaatgggat ctaccacagt
    21301 gaatttaaaa taatccagga ggccgggcat ggtggttcac gcctgtaatc ccagcacttt
    21361 aggaggccga ggtgggccga tcacgaggtc aggagatcga gatcatcctg actaacatgg
    21421 tgaaaccccg tctctactaa aaatacaaaa aattagcctg gcatggtggc gggcgcctgt
    21481 agtcccaact actcgggagg ctgaggcagg agaatggcgt gagcctgcga ggcagagctt
    21541 gcagtgagct gagatcatgc cactgcactc cagcctgggc aacagagtga gactccgtct
    21601 caaaaaaata ataataataa taataaaaat aatccaggcc atgtgtggtg gctcatgcct
    21661 gtaatcccag cattttggga ggccaaggag gcaggattgc ttgagtccag gagtttgaga
    21721 ccagcctggg caacacagac cccatctcta gaaaataaaa atttaaagaa attagctggg
    21781 catggtggtg tgcacctata gtcccagcta cttgggaggc tgaggcagga ggatggcttg
    21841 aacctgagag gtcgaggata cagtgagctg tgattgcacc actgcacttc agcctgggtg
    21901 acagagggaa accctgtctc tacataaata aatacataaa ataaaataat ccacaagcca
    21961 tttctactta actttgcaat gaactgtacc tgaccctaga tccctcccag tttggccctc
    22021 cggtatacaa gggcctccta taggcccttg tgatttctct ggggaaaagg aggactggag
    22081 ttgatcattt attgaggcca tcagaagcgg atggctaatt acatatggga catgtgttaa
    22141 taatgctttg tgtatataga gtggccttta ctttcaaaac actcttctcc aatttatcat
    22201 gttaaaagct aggaattggg ctgggtgcag tggctcacgc ctataatccc agcactttgg
    22261 gaggccaagg cgggtggatc atttgaggtc aggagtttga gaccagtctg accaacatgg
    22321 ttaaactccg tctctactaa aaatacaaaa ttagccaggc gtggtggcac acacctgtag
    22381 tcccaacaac tacttgtgag gctgaggcag gaaaatcatt tgaacccagg atcagaggtt
    22441 gtggtgaact gagattgcac cattgcactc cagcctgggc aacaagagca aaactctatc
    22501 tcaaaaaaaa taaaaaatag ccaggcacgg tggctcatgc ctgtaatcct agcactttgg
    22561 gaggcagagg tgggcagatc acctgaggtt aggagttcga gactagcctg gccaacatgg
    22621 tgaaacccca tctctactac aaatacaaaa attagctagg catggtggca gccacctgta
    22681 atcccagcta cttgggaggc tgaggcagga gaatcgcttg aacccgggag gtggaggttg
    22741 cagtgagcca agatcgggtc acagcactcc agcctaggca acagagcgag actccatctc
    22801 aaaaaaacat aaataaataa aaataaaaat aaataataaa taaaagctaa gaatcaaaga
    22861 agcagtttat tcctaatttc acagtctcat ctgttcatag tggggccagg attagagtca
    22921 gtggccaagc ttccatcctg ggttctttcc cttcccaggc cctaccatca tagtatacca
    22981 gggaaagacc tggagaagcc agcaggttga ccaccgaacc aaggctgggc caccttcctc
    23041 ctgggtctgg tctccagcct cccagttgta cccttccccc agcccttcct ggatgcactg
    23101 atcagcctgt gcttccttgc cctgtttttc tttataaata gagccatgtt ctcctctctc
    23161 tctctctctt tttttttttt ttttttttga gatggagtct tactctgtca cccaggctgg
    23221 agtgcaatgg cacgatctca gctcactgca acctctgtct cccaggttca agcaattctc
    23281 ctgcctcagc ctcccgagta gctgggatta caggtgccca ccaccatgcc cagctacttt
    23341 ttggattttt agtagagaca gggtttcacc atgttggtca ggctggtctt gaactcctga
    23401 ccttaggtgt tctgcccgcc tcagcctccc aaagtgctgg gattacaggc gtgagccacc
    23461 acgcctggca agacgtgttc tctctatgtt gttgaggctg gtcttgaact cctggctgca
    23521 agagatcttc ctgcctcagc ctcccaatgt gctgggatta taggcatgag ccaccacact
    23581 tagcccagcc tgtgctttct taaatgaaaa tctaagcata cggctgggtg tggtggctca
    23641 cgcctgtaat cccagcattt tgggaggcca aggtgggcag atcacgaggt caggagatcg
    23701 agactatcct ggccaacatg gtgaaaccct gtctctacta aagatacaaa aattagctgg
    23761 gtgtggtggc ccatgtctgt agtcccagct actcgggaga ctgaggcagg agaatggcat
    23821 gaacctggga ggcagagctt gcagtgagct gagatcgcgc cactgctctc cagcctaggt
    23881 gacagagcga gactccatct caaaaaaaaa ataaaaataa aaaaaagaaa atctaagcgt
    23941 ggtgctcccc tgctcaaaca tcctcaggtt cttttcatgg cagataaggg catctcttca
    24001 tgagccagcc cctgcctact gacccagcca cctctcccat cccttcccac cccgtacttc
    24061 aggcttcagc agtactgatc tttccaaaga ccccagaaca cacatgcctt catacctctg
    24121 tgcctgtaca tgcttgtttc tgcccttgaa atcatgacag tagctctctg taggccccgc
    24181 tagcctgtcc cttgggtctt agcctcttgg aggccttccc agagcccccc aaaagtaccc
    24241 caggcatact ttggttcctt ctctcatgtc ccctcagtac tttgcacata cctcctttat
    24301 agcagttgct atgttgtgcc agagaaggga gtcctgtggc tggggggcat atatcttttc
    24361 tttttgagac agagtctagc tgtgtcaccc aggctggagt gcagtagtgc gatctcggct
    24421 cactgcaacc tccacctcct ggattcaagc gattcttgtg cctcagcctc ctgagtagct
    24481 gggactacag gcgtgtgcca ccatcatgcc tggctacttt tttgtattag atatatattt
    24541 tctctcttag cacagtacct accaagagtg agtgagtaga tgtcctgacc cctgcaggca
    24601 tccaaggccc tccttccctg gacctgtttc cacatgtgtg aaggggtgca caggcagcag
    24661 cccacctctc agcttccttc cagttcttgt gttctgtgac cccttttcct catctctgcc
    24721 tgcttcctca cagcttgagg cagccctagg tgaggccaag aagcaacttc aggatgagat
    24781 gctgcggcgg gtggatgctg agaacaggct gcagaccatg aaggaggaac tggacttcca
    24841 gaagaacatc tacagtgagg tggggactgt gctttgcaag ccagagggct ggggctgggt
    24901 gatgacagac ttgggctggg ctagggggga ccagctgtgt gcagagctcg ccttcctgag
    24961 tcccttgccc tagtggacag ggagttgggg gtggccagca ctcagctccc aggttaaagt
    25021 ggggctggta gtggctcatg gagtagggct gggcagggag ccccgcccct gggtcttggc
    25081 ctcccaggaa ctaattctga ttttggtttc tgtgtccttc ctccaaccct tccaggagct
    25141 gcgtgagacc aagcgccgtc atgagacccg actggtggag attgacaatg ggaagcagcg
    25201 tgagtttgag agccggctgg cggatgcgct gcaggaactg cgggcccagc atgaggacca
    25261 ggtggagcag tataagaagg agctggagaa gacttattct gccaaggtgc ttgctctcga
    25321 ttggttccct cactgcctct gcccttggca gccctaccct tacccacgct gggctatgcc
    25381 ttctggggat caggcagatg gtggcaggga gctcagggtg gcccaggacc tggggctgta
    25441 gcagtgatgc ccaactcagg cctgtgcctc cacccctccc agtcaccaca gtcctaaccc
    25501 tttgtcctcc cctccagctg gacaatgcca ggcagtctgc tgagaggaac agcaacctgg
    25561 tgggggctgc ccacgaggag ctgcagcagt cgcgcatccg catcgacagc ctctctgccc
    25621 agctcagcca gctccagaag caggtgatac cccacctcac ccctctctcc aggggcctag
    25681 agtctgggcc ggatgcaggc tggaagccca gggttggggg tgggggtggg ggtgggaggt
    25741 tcctgaggag gagagggatg aaaagtgtcc ccacaaccac agagaagggt cgcaggatgt
    25801 ggagtcagat ggcctgtgtg ctgtttctgt acactcttac ctcaccttca cttctcaggg
    25861 ctttggtttt cccattcgaa aatggaggct gttcttaatc tccctaactc agagttgcca
    25921 caggactctg caatgtgagg tgttaaaagc atcagtattt ttctagttgg ctgtgctatt
    25981 tgtgacagga gaaaaagtct agcctcagaa cgagaggttt cagttagaca aggggaagga
    26041 cttcccagtt gccagccaag actatgttta gagcttgtga tgttcagagc tggctctgat
    26101 gagggctctg gggaagctct gattgcagat cctggagaga gtagccaggt gtctcctaca
    26161 ccgacccacg tccctccttc cccatactta gggcccttgg gagctcacca aaccctccca
    26221 ccccccttca gctggcagcc aaggaggcga agcttcgaga cctggaggac tcactggccc
    26281 gtgagcggga caccagccgg cggctgctgg cggaaaagga gcgggagatg gccgagatgc
    26341 gggcaaggat gcagcagcag ctggacgagt accaggagct tctggacatc aagctggccc
    26401 tggacatgga gatccacgcc taccgcaagc tcttggaggg cgaggaggag aggtgggctg
    26461 gggagacgtc ggggaggtgc tggcagtgtc ctctggccgg caactggcct tgactagacc
    26521 cccacttggt ctccctctcc ccaggctacg cctgtccccc agccctacct cgcagcgcag
    26581 ccgtggccgt gcttcctctc actcatccca gacacagggt gggggcagcg tcaccaaaaa
    26641 gcgcaaactg gagtccactg agagccgcag cagcttctca cagcacgcac gcactagcgg
    26701 gcgcgtggcc gtggaggagg tggatgagga gggcaagttt gtccggctgc gcaacaagtc
    26761 caatgaggta ggctcctgct cagggtctaa ggggatacag ctgcatcagg gagagagtgg
    26821 caagacagaa ggatggcatg tggagagagg aacatccttg ccctcagagg gtggaccagg
    26881 gtgagcctgt atatctcctc cacactctgg ttccaggcct ggctcctgga ctctttggct
    26941 gtgagacctt gagcaggtta tttaacctct cagagcatca gtttcctcat ctgtaaaatg
    27001 gggatgaata ctgatcccta agtctttgag ttgtcaggaa gatgaaagat aaggtatccg
    27061 tgtgcctggt gctgcgtatg tgtccacaga tcatggctat tatccccggg ggaagggcag
    27121 tgacaggggt gtgtgtagat ggaaggagag gcctcaattg caggcaggca gagggctggg
    27181 cctttgagca agatacaccc aagagcctgg gtgagcctcc ccgaccttcc tcttccctat
    27241 cttcccggca ggaccagtcc atgggcaatt ggcagatcaa gcgccagaat ggagatgatc
    27301 ccttgctgac ttaccggttc ccaccaaagt tcaccctgaa ggctgggcag gtggtgacgg
    27361 tgagtggcag ggcgcttggg actctgggga ggccttgggt ggcgatggga gcgctggggt
    27421 aagtgtcctt ttctcctctc cagatctggg ctgcaggagc tggggccacc cacagccccc
    27481 ctaccgacct ggtgtggaag gcacagaaca cctggggctg cgggaacagc ctgcgtacgg
    27541 ctctcatcaa ctccactggg gaagtaagta ggcctgggcc tggctgcttg ctggacgagg
    27601 ctccccctga tggccaacat cggagccagc tgcccccaac ccaagtttgc caattcaggg
    27661 cccctttcta gagctctctg ttgcaggctc cagacttctc cacccagtag gcaaaccaaa
    27721 agatgcttcc tcaacagcac aaggggtgga agttagacag tgaggattgt taaaggcaga
    27781 gccatactcc tacccggaga gcttgacagt gtccctctgg ggtggaaatg agttccttag
    27841 ctccatcacc acagaggaca gagtaagcag caggccggac aaagggcagg ccacaagaaa
    27901 agttgcaggt ggtcactggg gtagacatgc tgtacaaccc ttccctggcc ctgacccttg
    27961 gacctggttc catgtcccca ccaggaagtg gccatgcgca agctggtgcg ctcagtgact
    28021 gtggttgagg acgacgagga tgaggatgga gatgacctgc tccatcacca ccacgtgagt
    28081 ggtagccgcc gctgaggccg agcctgcact ggggccaccc agccaggcct gggggcagcc
    28141 tctccccagc ctccccgtgc caaaaatctt ttcattaaag aatgttttgg aactttactc
    28201 gctggcctgg cctttcttct ctctcctccc tataccttga acagggaacc caggtgtctg
    28261 ggtgccctac tctggtaagg aagggagtgg gaactttctg atgccatgga atattcctgt
    28321 gggagcagtg gacaagggtc tggatttgtc ttctgggaaa gggaggggag gacagacgtg
    28381 gggcatgccc gccctgcctc tctcccccat tcttgttgca tgcatatcct ctcatttccc
    28441 tcatttttcc tgcaagaatg ttctctctca ttcctgaccg cccctccact ccaattaata
    28501 gtgcatgcct gctgccctac aagcttgctc ccgttctctc ttcttttcct cttaagctca
    28561 gagtagctag aacagagtca gagtcactgc tctggttctc tgtccccaag tcttcctgag
    28621 ccttctcccc ttttatgtct tccctctcct cctccgggcc cctagcctcc caaaccccca
    28681 ttgcccgctg gctccttggg cacagaacca caccttcctg cctggcggct gggagcctgc
    28741 aggagcctgg agcctggttg ggcctgagtg gtcagtccca gactcgccgt cccgcctgag
    28801 ccttgtctcc cttcccaggg ctcccactgc agcagctcgg gggaccccgc tgagtacaac
    28861 ctgcgctcgc gcaccgtgct gtgcgggacc tgcgggcagc ctgccgacaa ggcatctgcc
    28921 agcggctcag gagcccaggt gggcggaccc atctcctctg gctcttctgc ctccagtgtc
    28981 acggtcactc gcagctaccg cagtgtgggg ggcagtgggg gtggcagctt cggggacaat
    29041 ctggtcaccc gctcctacct cctgggcaac tccagccccc gaacccaggt gagttgtctc
    29101 tgctttgtct ccaaatcctg caggcgggtc cctggtcatc gaggggtagg acgaggtggc
    29161 cttgcagggg ggagagcctg ccttctcttc cgcagcccgg gggagtggga gcctcctccc
    29221 cacagcctga gtcctagaca gcccacctct gcatcctgcc cctcttgtct gagccccaga
    29281 ctggagggca ggggcagggc tggagtgtga gggatggggg agatgctacc tcccttctag
    29341 gggccagggg agggagggtc tgggtccagg ccctgctgct cacacctctc tcctctgttt
    29401 tctctcttag agcccccaga actgcagcat catgtaatct gggacctgcc aggcaggggt
    29461 gggggtggag gcttcctgcg tcctcctcac ctcatgccca ccccctgccc tgcacgtcat
    29521 gggagggggc ttgaagccaa agaaaaataa ccctttggtt tttttcttct gtattttttt
    29581 ttctaagaga agttattttc tacagtggtt ttatactgaa ggaaaaacac aagcaaaaaa
    29641 aaaaaaaagc atctatctca tctatctcaa tcctaatttc tcctcccttc cttttccctg
    29701 cttccaggaa actccacatc tgccttaaaa ccaaagaggg cttcctctag aagccaaggg
    29761 aaaggggtgc ttttatagag gctagcttct gcttttctgc cctggctgct gcccccaccc
    29821 cggggaccct gtgacatggt gcctgagagg caggcataga ggcttctccg ccagcctcct
    29881 ctggacggca ggctcactgc caggccagcc tccgagaggg agagagagag agagaggaca
    29941 gcttgagccg ggcccctggg cttggcctgc tgtgattcca ctacacctgg ctgaggttcc
    30001 tctgcctgcc ccgcccccag tccccacccc tgcccccagc cccggggtga gtccattctc
    30061 ccaggtacca gctgcgcttg cttttctgta ttttatttag acaagagatg ggaatgaggt
    30121 gggaggtgga agaagggaga agaaaggtga gtttgagctg ccttccctag ctttagaccc
    30181 tgggtgggct ctgtgcagtc actggaggtt gaagccaagt ggggtgctgg gaggagggag
    30241 agggaggtca ctggaaaggg gagagcctgc tggcacccac cgtggaggag gaaggcaaga
    30301 gggggtggag gggtgtggca gtggttttgg caaacgctaa agagcccttg cctccccatt
    30361 tcccatctgc accccttctc tcctccccaa atcaatacac tagttgtttc tacccctggc
    30421 tgctgtggtg tctttgttgg tggacgtcgc tgtgtgtact gaggtgcaga ctcgtgggca
    30481 tgcgcgcgcg tacacacaca cacacacaca cacacacaca cacacacaca cacacagcgc
    30541 cgcacggtca ctgcatcctc ctgctcattg ctgcccagcc ctgccctgct ccaggggaaa
    30601 caattagaga tcagagcact ttgggtgcac atctgggcac tcggtggtgg ctgaggggga
    30661 aggctttgat ataaccatca ccacccactg tacggctctc tcccaacgga agtccttcag
    30721 agaagcagca cctgaaggag ggcatttgct aactaacttc cctcgtccac cagcacttac
    30781 tgagtgcttt ctctgtgctg ggccctgagc gaagcatgaa tataagacat atgatataga
    30841 cccagtctga gggtggtgac atatcaggac gtaaggacaa ggacacccgg ggaggaggga
    30901 acagaagctg caggagaggg cagaggaaag gagcagttaa tgtccctttg tgccatgttg
    30961 tgctcaggtt gggggattgg gaaatgaaca agacaagatg cccactgtcc tcagagaaat
    31021 tacaccccag tgggagtcag aaaatagact gcagacaaag ggatatgtta ggccaagtag
    31081 gagcctccga gggggttcca acctgggggc atgaggtgcc cagactgagg ggaggggccc
    31141 caaacaggga aaatgagcta tagaagccag cctttctctg gcccttccta gtttccaaag
    31201 catttctgca gcatctcatt tggccttcgt actgtcttga gaggtaggta ttgtctccca
    31261 gccctctgga actcaggcca ctcagctcga aggtggcaca gatcccaaga ttctggaagt
    31321 ttatttatgt tccttgggca gagttgagcc tgcagtcaag agtcagtgag aaacgggcat
    31381 gtctggctgg gatcgtggga aaacatgtga gaaagcaaaa ttactgagag gagaagggcc
    31441 cctgaggtca tgctggacgc tcctgattcc accataggct gagaccccac agtgccttta
    31501 gggaagggaa gttaagcgga aggaggtttg aggaaggggt ccctgcttgg gttggcagtt
    31561 tccaagaagg aaacccttcc tctcctaggc ctcagcaaag accctgaggc cccgcagata
    31621 tggggtctta gatgtcagcg agggagtccg tgtgtcccaa aatgaggact cccacctgca
    31681 gttcctgggt cgggcacctt ggggcgccag agccccacca cggtggtgcc tgcacatcct
    31741 gggtaggggt ccttcgctac tcagctgaac cctggtgagc tggctgcatg ggcactgtgg
    31801 gctggggaac accaggggca gcaggcaacg ttcctagctc ttgaggagga gggctgaggg
    31861 catagggccg cacacaaaca ctgccccaca agctggcagc acggcggggg cggcagccgg
    31921 ggactcagca gttaaggtgt ccacacacgt ggtcacctca catgatgctc acagcacaag
    31981 tcagcactca gcagccacat ttcattatgt aaaaaaaaaa aagttgttgt tgttaaaatg
    32041 taatacatgc ttggcctagc gtggtggcac gcacgcctgt agtcccagca actcctggcc
    32101 tgaggcggga aaattgtctg agctcaggag ttctaggcca gcctgggcaa cagcaacaac
    32161 aaaaatacat atcatatggt aaaattcaaa acacaggtaa gggatggaca cagtggctca
    32221 cgcctgtaat cccagcactt tgggaggctg aggtaggcgg atctcaggtc aggagtttga
    32281 gaccagcctg gccaatgtgg caaaatgcct ctactataca aaaattagct gggtgtggtc
    32341 gtgcatgcct gtaatcccag ctattcggga agctgaggca ggaggatcgc ttgaactggg
    32401 tggcttatgt tgcagtga
//

