LOCUS       NG_021411              10123 bp    DNA     linear   PRI 08-JUN-2010
DEFINITION  Homo sapiens kelch repeat and BTB (POZ) domain containing 13
            (KBTBD13), RefSeqGene on chromosome 15.
ACCESSION   NG_021411
VERSION     NG_021411.1  GI:297632374
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC013553.14.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The gene belongs to a family of genes encoding proteins
            containing a BTB domain and several kelch repeats. The BTB domain
            functions as a protein-protein interaction module, which includes
            an ability to self-associate or to interact with non-BTB
            domain-containing proteins. The kelch motif typically occurs in
            groups of five to seven repeats, and has been found in proteins
            with diverse functions. Known functions of these family members
            include transcription regulation, ion channel tetramerization and
            gating, protein ubiquitination or degradation, and cytoskeleton
            regulation. The exact function of this family member has yet to be
            determined. [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10123             AC013553.14        80951-91073
FEATURES             Location/Qualifiers
     source          1..10123
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q22.31"
     gene            5001..8123
                     /gene="KBTBD13"
                     /gene_synonym="HCG1645727"
                     /note="kelch repeat and BTB (POZ) domain containing 13"
                     /db_xref="GeneID:390594"
                     /db_xref="HGNC:37227"
     mRNA            5001..8123
                     /gene="KBTBD13"
                     /gene_synonym="HCG1645727"
                     /product="kelch repeat and BTB (POZ) domain containing 13"
                     /transcript_id="NM_001101362.2"
                     /db_xref="GI:297591828"
                     /db_xref="GeneID:390594"
                     /db_xref="HGNC:37227"
     exon            5001..8123
                     /gene="KBTBD13"
                     /gene_synonym="HCG1645727"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             5001..6377
                     /gene="KBTBD13"
                     /gene_synonym="HCG1645727"
                     /note="kelch repeat and BTB domain-containing protein 13"
                     /codon_start=1
                     /product="kelch repeat and BTB domain-containing protein
                     13"
                     /protein_id="NP_001094832.1"
                     /db_xref="GI:157384932"
                     /db_xref="CCDS:CCDS45281.1"
                     /db_xref="GeneID:390594"
                     /db_xref="HGNC:37227"
ORIGIN      
        1 agcccttctc cagccctgcc cccagcagaa ggcaactgtt tccctgccct gagacaaggc
       61 tagtgcaggt gaggagtggc agctagggtc agtgggcagg gttcgattga gcctcacatc
      121 cccattcata accaaggaaa agcccaaatc atttctaagc ctttgtttcc tcgtctgtga
      181 aatgggaata gtcagacact ctttccctac cactaaggcc accagcaagg acacagtcaa
      241 gacccagcac tgagagccca ctggtcccca agattgggac tgtcatgcct gctgcctgga
      301 catcccagac cattcagcca atatctggcc ttggggaaag aaagaaactg gcagagggcc
      361 tgggatagta ttcatgggga cttctgccca cccatccccc catctcctcc tcctcttcct
      421 gtctggtccc tggggcagag tcagagatat ttctggctgc ctcctccagg cctctggctt
      481 cccaggctca cacaagtggt ccccacatcc catcactgct ttgatggagt gaactggatg
      541 ggagttccct agcaggggag gcacatttgt gttggctctg cagattcata cgtgaggatc
      601 tatgcatatg tatcctaagg gggagagaag ttcccctgcc tcttcccacc ttctacttgg
      661 tcattgtgag ccactcattc tccctaagaa ggcctgcagg taaggatggg gagctaaaca
      721 tctgaatggc agataccatt ttacacgtct gggcctcagt ttcctcacct tagaataggt
      781 ggcaagagga gataattatt aagctccatt ccatcccaag ctccactttt ggacccatag
      841 ttttagctgg tcacctagaa aagttctgtg tagtgggaaa agtgccatgg agtgggcagc
      901 aggaggcctg aggctgtctg cttcaagcta caagaccctg agcacttccc tccactgtga
      961 gaggattgaa ccatatgagc ctgaggtgcc tttcagctat gccctcctga cacaaggtga
     1021 ctgcccagca tttgtagcac agagaggcat cggagcacag tggtatggcc cagcactttg
     1081 ggaggccgag gtgagaggat cacttgaggt caagagttca agaccagcct ggccaacaag
     1141 gtgaaacccc gtctctactg aaaatacaaa aattaaccag gtgtgggtta ctctgtcact
     1201 ctgggtgaca gagtgagact ccgtctcaaa aaaagaaaca aacaaacaaa aaaaccccaa
     1261 accaacgaac caaacaaaca aacaaaaacc gacaacaaaa aacacagtgg tatgggcatg
     1321 ccctctagca gtccccaacc tttttggcac cagggattgg ttttgtaaaa gacagttttt
     1381 ccacagacag cggaggggag atggtttcgg aattattcaa gcgtattaca tttattgtgc
     1441 attttatttc tattattatt ataacatata atgaaatact tacacaactt gccataatgt
     1501 agaatccatg ggtgtcctga gcttgttctc ctgcaactaa acagtcccat ctggaggtga
     1561 tgggagacag tgacagatca tcaggcatta gattgtcata aggagcaggc aacctagata
     1621 cctcccacat gcagttcaca atagggttcg ccctccaatg agaatcaaat gctgctgcca
     1681 ctgatctgac agaaggcagc actcaggcag taatgaggat ggggagcggc tgtaaatata
     1741 gatgaagctt tgcttgctca ctgctcacct ctggctgcgc ggcctggttc ctaaggtcca
     1801 tggccccagg gttggggacc cctgctttag aatcaggctg gctgcattcc aggcctaggt
     1861 ctgccactct ctggctatgt gactaaacct cttggtgctt cagtctcttc atatatgaaa
     1921 taaggccatt aataatttct aattcatagt gttgctataa gcaataaatg gataatatcc
     1981 atggggggag aaataatagt atctactcct gggattgttg taaggactta gtataaagtg
     2041 cttacaacag tgcctgacac ataatgcaat taaagtgtta gctattatta tttcaggaag
     2101 cccttcttcc catccacaag catatgatcc cctaggcagc cccaattcct tttcccagga
     2161 tctggagcct cgcagcaagt gtggaattcc catccccatc ccaagtcagg ggctttatgg
     2221 gatgctcatc tgcaaagcag ggttgctacc tttcccattt ttcaggaaga aaattgagac
     2281 tcaaaaagag attggactgg ctcagagtca gagtcagaag cccaagccaa attaaaaccc
     2341 tggtcctgta ccccagcctg gcccaatgta cttgctccat ttctgccttg ttctccaacc
     2401 tgcctgtccc actcctctga gctgaagggg tgaggtgggt attcattctg ccccagcttc
     2461 ttcctagctg aatgaccctg gacaagttac ctaaagtctt tcagcctcaa ccgggatatt
     2521 tcggatactg tcccatgact gtgaaatagg tgttattatt ggccccattt tattttttaa
     2581 ttaatttttt ttttttgaga cagatcctca ctctgttgcc taggctggag tgcaatggca
     2641 cgagctcggc tcactgcaac ttcagcctcc cgagttcaag ctgttctcgt gcctcagcct
     2701 cataaagtag ctggtattac aggcacgtgc caccacgccc ggctaatttt tttgtatttt
     2761 taatagagac ggggtttccc catgtcggcc aggctggtct caaactcctg acctcaggtg
     2821 atcaaccatt ctcggccccc aaaagagctg ggattacagg aatgagccac cgttcctggc
     2881 ctactggtcc catttggaac atgaggaacg gttaggacat tcgcacgagg gcacacagct
     2941 ggaaagatgc aggtgaaatg ggtatctccc tagcagccct cagtgcgccc gcacgctgca
     3001 ggtgcacggt atatggtcac tattattgag aggtgacagc atgctggcag tcctcagagc
     3061 cctcgcttgc tctcggcacc tcctctgcct gggctcccac tttggcggca cttgtggagc
     3121 ccttcagccc accactgcac tgtgggagcc cctttctggg ctggccaagg ctggagccca
     3181 ctccctcagc ttgcagggag gtgtggaggg agaggcgcga gcgggaaccg gggctgcgtg
     3241 tggcgcttgc gggccagctg gagttccagg tgggcgtggg cttggcgggc cccgcactcg
     3301 gagcagtcag ccagccctgc tggccccggg caatgaggga ctttgcaccc gggccagtgg
     3361 ctgcggaggg tgtactgggt cccccagcaa tgccagccca ccggcgctgt gcttgatttc
     3421 tcaccgggcc ttagctgcct tcccgcaggg cagggctcag gacctgcagc ccgccatgcc
     3481 tgagcctccc atccactcca tgggctcctg tgcggcccga gcctccccga cgagcactac
     3541 cccctgctcc acggtgccca gtcccatcaa ccacccaagg gctgaggaat gcgagcgcat
     3601 ggtgcaggac tggcaggcaa ctccacctgc agccctggtg caggatccac taggtgaagc
     3661 cagctgggct cctgagtctg gtggggacgt ggagagtctt tatgtctagc tcagggattg
     3721 tgaatacacc aatcggcact ctgtatctag ctcaaggttt gtaaacacac taatcagcac
     3781 cctgtgtcta gctcagggtt tgtgagtgca ccaattgaca ctctgtatct agctgctctg
     3841 gtggggccct ggagaacctt tatgtctagc tcagggattg taaatacacc aattggcact
     3901 ctgtatctag ctcaaggttt gtaaacacac caatcagcac cctgtgtcta gctcagggtt
     3961 tgtgagtgca ccaatcaaca ctctgtatct agctgctctg gtggggcctt ggaaaacctt
     4021 tatgtctagc tcagggattg taaatacacc aatcggcact ctgtatctag ctcaaggttt
     4081 gtaaacacac caatcagcac cctgagttta gttcaaggtt tgtgagtgca ccagtcgaca
     4141 ctctgtatct agctgctctg gtggggcctt ggagaacctg tatgtggaaa ctctgtatct
     4201 aactaatctg atggggacgt ggagaacttt tgtatctagc tcagggattg taaacccacc
     4261 aatcagcgcc ctgtcaaaac aggccacttg gctctaccaa tcagcaggat gtgagtgggg
     4321 ccagataaga gaataaacgc aggctacccg agccagcagt ggcaacccgc tcatatcccc
     4381 ttccacactg tggacgcttt attcttttcc tctttgcaat aaatcttgct gctgctcact
     4441 cttttgggtc cacactgctt ttatgagctg taacactcac cgtgaaagtc tgcagcttca
     4501 ctcctgaggc cagcgagacc acaagcccac tgggaggaac gaacaactcc agacacgctg
     4561 ccttaagagc tgtaacactc acagcgaagg tctgcagctt cactcctgag ccagcgagac
     4621 catgaaccca ccagaaggaa gaaactccaa acacatctga acatcagaaa ggacagactc
     4681 cagacacgct accttaagag ctgtaacact cacctcgagg gtccgcggct tcattcttga
     4741 agtcagacca agaacccacc aattctggac ccattattac catttcttct aaggatatga
     4801 gtgatcacac aggtctccag atgccctccg ggcctgcagc catacagcct gcgggccacc
     4861 acatcacatg agccatacta tctttagcca gggagagata tttatagccc ccagggaagt
     4921 tttttgctcc aggggagccc cagagttggt ggctggctaa cccaaggccc cagcggcagc
     4981 ctccgcccgg ccagctcgcc atggcacggg gtccacagac cctggtgcag gtgtgggtgg
     5041 gcggccagct cttccaagcc gaccgcgccc tgctggtgga gcactgtggc ttcttccgag
     5101 gcctcttccg ctccggcatg cgggagaccc gcgcagcaga ggtgcgcctg ggcgttctga
     5161 gcgcgggagg tttccgcgcc acgctgcagg tgctgcgcgg cgaccggccg gcgctggcgg
     5221 cggaggacga gctgctgcag gccgtggagt gcgccgcctt cctccaggcg ccggcgctgg
     5281 ctcgctttct ggagcacaac ctcacgtcgg acaactgcgc attgctgtgc gacgcggccg
     5341 ccgccttcgg cctgcgcgac gtgttccaca gtgccgcgct cttcatctgc gacggcgagc
     5401 gcgagctggc ggccgaactg gcgctgcctg aggcccgcgc ctacgtggcg gccctgcggc
     5461 ccagcagcta cgcggccgtg agcacgcaca cgcccgcgcc cggcttcctg gaggacgcct
     5521 cgcgcacgct gtgttacctg gacgaggaag aggacgcgtg gcgcacgctg gctgcgctgc
     5581 ccctggaggc cagcacgttg ctggccgggg tggccacgct gggcaacaag ctttacatcg
     5641 tggggggcgt gcgcggcgcc agcaaggagg tggtagagct gggcttctgc tacgaccccg
     5701 acggcggcac gtggcacgag ttccccagcc cgcaccagcc gcgctatgac acagcgctgg
     5761 ccggcttcga cggccgcctc tacgccatcg gcggcgaatt ccagaggacg cccatcagct
     5821 ccgtggagcg ctacgaccca gccgcgggct gctggagttt cgtggccgac ctgccgcagc
     5881 cggccgccgg cgtgccctgc gcccaggctt gtggccgtct cttcgtgtgc ctgtggcggc
     5941 cggccgacac caccgccgtg gtggagtacg cagtgcggac cgacgcgtgg ctgccagtgg
     6001 ccgagctgcg gcgtccgcag agctatggcc actgcatggt ggcccaccgc gacagcctct
     6061 atgtggtgcg caacggacct tccgacgact tcctgcactg cgccatcgac tgtctcaacc
     6121 tggccacggg ccagtggacg gcgctgcccg gccagttcgt caacagcaag ggagcgctct
     6181 tcacggccgt ggtgcgcggt gacaccgtct atacggtcaa ccgcatgttc acgctgctct
     6241 acgccatcga gggcggcacc tggcggctgc tcagggagaa agccggcttc ccgcggcccg
     6301 gctccttgca gacctttctc ctaaggctgc ctcctggcgc tcctgggcct gtgacttcga
     6361 caacggcaga actgtgacct ctgggctggc tttaggaggg aggagacgcc gcgactcctc
     6421 cctgagctat ggctgagtgt gtgaggccgg ccttagaagt agctggcaac ttccctcttt
     6481 ctactgagac acccaggttt ggtgccttct ggtggtgtgg acatgttcaa gaagctcagg
     6541 gagcagtgat gatgccctca aattacttgg gctctgctga gagctggtgg gtcacaatgt
     6601 cagtgaacag ggtaggggga gttgggattt gaataatccg ggcttatatg taatgggcta
     6661 gtgattgagc atcgctggga gcgacttaaa tgatgttaat caaactgcaa gtagtaggca
     6721 agaattaggc acctactgta tgcccaatac agtgttatgc gtaatgagag ccgtagttgc
     6781 cacacaggga tccaggaagc ttaaaggata acccagaaaa caatcttaac agttacagga
     6841 caacaaaaag gtttacacac aacttgatcc acagagttga aggcaacatg caaaaaaatt
     6901 taaaaccgca tacaatataa taaaataaag tgctgaagaa atcagggcaa agggaaaata
     6961 ggaagagaaa aaatatataa ctccagaaaa gaagagagtg tgcaaactct atggaggaga
     7021 tgagcaggat accattagct gctgaaaggg gaggcttaga ccatggaggc tgagagctca
     7081 gaagagaagc agggttgggg aaggctggag cagatgggga gggtctctgc aagtccagcc
     7141 ataccagcag agcagcagta gttggggcat ctagagaggg gatgagactg ggccagcttg
     7201 cagcagataa tgactgagct gagcctggag tgagacctgt gggggcgaga ggattcttca
     7261 cgttcctttt tggaaccctt aggggagcac ccaggtgtaa gcccttgccc accctgtttt
     7321 tgccatcacc acggggcagt ggactgttaa cccacatgac ttcaggtcag ttgaggtatg
     7381 agccaaatcc tgcctcatct tcctcagttg tagcccctcc tccacattct acaggtttgt
     7441 tctcttcctg tcctattctg ccctttgcaa ttccctgggc tggaatgcct agtctcctcc
     7501 tctctccctg tcagtgctct accatcctct gtgcagcatt ggctcaccca gctcttcgtt
     7561 ttcctgacct gggctgcctg cattgctcat tggacccctg gctgtaacat cattgtgtgt
     7621 gcacaaccac gtgtgtggat tgtaagggca gagatcctgt taagtgagct gggggacttc
     7681 cctgtcccag attaaaatga tgatgccttg aaagaaccca ggctacagag gccactagtt
     7741 aggaacctag tgctgacctc tgttgttgga tgaggactct cgttccttca tcaaaatccc
     7801 cagctctggc ttctgggcag atgcctgtcc cagccctttc cagcctctcc atggccttgg
     7861 gaagacttct ctgggtggtt ctcattggtc tccatccccc aggacctgag gcccatgggg
     7921 aatcttggcc tcgtcagaag tggagaatgc agtgtcagca tgacacctcc ggggcatgga
     7981 ggctcgcgcc agggctgcac ctagctgcct cttctcctgg cctatgtccc aaccctggag
     8041 aatgctgccc tcagaagcct gggaccttcc agccctggag tagcctagtc tgataagtct
     8101 caacaataaa ccctgacttt tgcatcttgt gaattatgtg caaggtactt tcacatctga
     8161 cttccccctc ccgacctacc ttgggcctgg gagttgggta ccctcttctt gtggcagaaa
     8221 ctgacccact ggcccaaagc cacacagcat agcaacaaga gttcctcact tgtagttcta
     8281 tcaaagtgta attcattcat tctttttttt ttttcttttt gacacagggt cttgctttgt
     8341 cagtctggag tacagtggta aaatcatggc ttactgcagc cttaacctcc tgggctcagg
     8401 tgatcctcct accttagcct ccccagtagc tgggactaca ggtgcacacc accacaccta
     8461 gctaattttt ataatttttt ttttgagaca gagttttgct gtagttgccc aggctggggt
     8521 gcaatggtgt gatctcagct caccccaacc tccacctccc aggttcaagt gattctcctg
     8581 cctcagcctt cccaagtagc tgggattata ggcatgcgcc accaagcctg gctaattttg
     8641 tatttttagt agagatgggg tttctccatg tgggtcaggg tggtcttgaa ctcctgacct
     8701 caggtgatcc gcccacctcg gcctcccaaa gtgctgggat tacaggtgtg agccaccacg
     8761 cccggccaat ttttatacaa tttttttgta gaggtggagt ctcactgtgt tgcccaggtt
     8821 ggccttgaac tcctgggctc aagcaatcct cctgcttggc ttccgaaagt tctgggatta
     8881 caggcatgag ccactgtacc tggcctcaaa gtgtaattca tatcacacat caaagattta
     8941 tttaactcac ctgtaagaga accaaaaaga atggcaaagc tgattgaaaa gagcatttga
     9001 gagacagatt tgtatattta gttggaagag acatactaaa ataagtttgc taagttagag
     9061 acaaaactgg catatgcctt acaggacaaa agcataattt ttttggttct ctactgaaca
     9121 aaaatccttt gcatctttac atacatgcat gtacatattt gtgcatatgc ctacaagtta
     9181 gcatgtaact tcacaaagtc tgggctctaa tctatagtaa attgtaaggc aaaggtacat
     9241 tccccttgaa aattaaataa ctcttctctg ttcaaagtgt cccaaagtga cattgaaagg
     9301 aaataatcct tcttttgcct tacttccaag ttacagataa ctttcataac agtacagagc
     9361 attttcctcc ttcctcctga ccagtgctga acacctgaga cttgccacat gataatccat
     9421 cagctcctag tctctcttat cccacagcat tgtctgcact tggggctgct tagccccagc
     9481 ctgctggctc ctggcatttg gttgttcctc ccttcatcca gggcagccct ttctgagatg
     9541 ccttttgtgc gtaataataa cacagtgttc acagagagct ttcccacagt tgacttactt
     9601 gagcttttga gaattttaag tggcagatag tttggcaaca cccctactcc cgcagcttaa
     9661 tggagggaaa aaagctcaac ggtcatgtga ttagaagagg ctcgttaggt agtggcagaa
     9721 cctggctgtg aacccagggc cacaggcttg tcttctgtgc tacatgcctg cttggccgac
     9781 atcctgagat ggacagggtg tttccaatgg tctccttaac actccctccg ttttgccttt
     9841 ctctatgtat ccccacctct tttgggggtt cgtttgttcc cttggactca gccctttctc
     9901 ttccctcttc cataggaaag ttaactagtt ctcttccctt aggatagacc tgggagacca
     9961 gtagccccgt tcagcccagg taatgactgg tttaggccct gggggatatt tgcacgttca
    10021 ctgatacttc cctcgtctca ggaagtgtgg ggaagctttg taacccagcc caccttctct
    10081 gtctaagggt tctcacagtt aaggctttgt tccacccaca gtc
//

