LOCUS       NG_011857              13867 bp    DNA     linear   PRI 14-MAR-2010
DEFINITION  Homo sapiens iron-sulfur cluster scaffold homolog (E. coli) (ISCU)
            on chromosome 12.
ACCESSION   NG_011857
VERSION     NG_011857.1  GI:226693385
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC008119.6.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: Iron-sulfur (Fe-S) clusters are necessary for several
            mitochondrial enzymes and other subcellular compartment proteins.
            They contain sulfur and iron, and are created via several steps
            that include cysteine desulfurases, iron donors, chaperones, and
            scaffold proteins. This gene encodes the two isomeric forms, ISCU1
            and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this
            gene have been found in patients with myopathy with severe exercise
            intolerance and myoglobinuria. [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5183              AC008119.6         105611-110793
            5184-5184           "G"                1-1
            5185-13867          AC008119.6         110794-119476
FEATURES             Location/Qualifiers
     source          1..13867
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.1"
     gene            complement(<1..3872)
                     /gene="SART3"
                     /gene_synonym="DSAP1; KIAA0156; MGC138188; P100; p110;
                     p110(nrb); RP11-13G14; TIP110"
                     /note="squamous cell carcinoma antigen recognized by T
                     cells 3"
                     /db_xref="GeneID:9733"
                     /db_xref="HGNC:16860"
                     /db_xref="MIM:611684"
     STS             620..766
                     /standard_name="D12F290S2"
                     /db_xref="UniSTS:157485"
     mRNA            complement(<3326..3872)
                     /gene="SART3"
                     /gene_synonym="DSAP1; KIAA0156; MGC138188; P100; p110;
                     p110(nrb); RP11-13G14; TIP110"
                     /product="squamous cell carcinoma antigen recognized by T
                     cells 3"
                     /transcript_id="NM_014706.3"
                     /db_xref="GI:119393885"
                     /db_xref="GeneID:9733"
                     /db_xref="HGNC:16860"
                     /db_xref="MIM:611684"
     CDS             complement(<3326..3637)
                     /gene="SART3"
                     /gene_synonym="DSAP1; KIAA0156; MGC138188; P100; p110;
                     p110(nrb); RP11-13G14; TIP110"
                     /note="tat-interacting protein of 110 kDa; SART-3;
                     hSART-3; squamous cell carcinoma antigen recognized by
                     T-cells 3"
                     /codon_start=1
                     /product="squamous cell carcinoma antigen recognized by
                     T-cells 3"
                     /protein_id="NP_055521.1"
                     /db_xref="GI:7661952"
                     /db_xref="CCDS:CCDS9117.1"
                     /db_xref="GeneID:9733"
                     /db_xref="HGNC:16860"
                     /db_xref="MIM:611684"
     STS             3429..3544
                     /standard_name="RH25375"
                     /db_xref="UniSTS:89125"
     gene            5001..11867
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /note="iron-sulfur cluster scaffold homolog (E. coli)"
                     /db_xref="GeneID:23479"
                     /db_xref="HGNC:29882"
                     /db_xref="MIM:611911"
     mRNA            join(5001..5219,6543..6638,6762..6875,7804..7914,
                     9673..9751,11314..11867)
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /product="iron-sulfur cluster scaffold homolog (E. coli)"
                     /transcript_id="NM_014301.3"
                     /db_xref="GI:190883481"
                     /db_xref="GeneID:23479"
                     /db_xref="HGNC:29882"
                     /db_xref="MIM:611911"
     exon            5001..5219
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     misc_difference 5184
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /note="This sequence differs from the reference genome
                     assembly (NCBI Build 36) at this position. G was inserted
                     to represent the standard allele identified by alignment
                     of public cDNAs."
     exon            6543..6638
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     CDS             join(6600..6638,6762..6875,7804..7914,9673..9751,
                     11314..11399)
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /note="isoform ISCU1 is encoded by transcript variant 1;
                     nitrogen fixation cluster-like; NifU-like N-terminal
                     domain containing; IscU iron-sulfur cluster scaffold
                     homolog; nifU-like protein; nifU-like N-terminal
                     domain-containing protein; iron-sulfur cluster assembly
                     enzyme ISCU, mitochondrial"
                     /codon_start=1
                     /product="iron-sulfur cluster assembly enzyme ISCU,
                     mitochondrial isoform ISCU1"
                     /protein_id="NP_055116.1"
                     /db_xref="GI:24307953"
                     /db_xref="CCDS:CCDS9118.1"
                     /db_xref="GeneID:23479"
                     /db_xref="HGNC:29882"
                     /db_xref="MIM:611911"
     exon            6762..6875
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            7804..7914
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            9673..9751
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            11314..11867
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     STS             11649..11778
                     /gene="ISCU"
                     /gene_synonym="2310020H20Rik; HML; hnifU; ISU2; MGC74517;
                     NIFU; NIFUN"
                     /standard_name="D12S1907"
                     /db_xref="UniSTS:67736"
ORIGIN      
        1 agggaaggga gaatggagca gcacctatta tgcgccaaac tgtgccaggc gctttacgca
       61 cattgtgcca tgccccacaa cagtcccatg aggaaagcac tattacaacc ttcattttac
      121 taactgggac acccaagact ctgcgagctg aaataacttg tacaaggcct ttccactact
      181 caatggaagg cttgggttca gggttgcaaa gccatagtct ccgtactgct gcactgacaa
      241 atctgccgaa gccaccatga agtgccactt ttaatttcag cgcacaaaca catataatgg
      301 aaaatatttg cttttgttag acagatacca cagcaaactg ccagctacca taaaatataa
      361 tcaaggccac gtgcagtagc ttgcgcctgt gatccgagca ctttgggagg ctgaggcagg
      421 agcatcactt cagctcagga attcagcacc tgcctgggca acatagtaag aacccatctc
      481 tacaaaaaaa aaatattttt aattagccag gcatgggggt gcatgcctgt agtccgagat
      541 actttggagg atgagctggg aggatcactt gagcctggga ggtcctagct gcagtgagcc
      601 atgatcacac cactactcca gcatgggcaa gagtgagatg ctctcaaaaa aaaaaattaa
      661 taaacactga gggatgagaa ccagaactct caaatatggc aaggccaagt ttctcacaga
      721 cctatttgga agcaattcat cattatgctc cgccataaaa gcagttacag caggaagaag
      781 cagctgtggg atcaggatga ggtgggtggg aggcttggag aaactggaca agtccatttc
      841 tagaccacag gacaaagagg ataaggccag agggtcttca gttcatcact tgccaggtcc
      901 tatcctgtgt ggtccattct aaactccacc ccatccttgg tgatctgtgg caggacaggc
      961 aactgcagag tactagtggc cagagacctc tgctctcccc tttcttgctc tttagcaagc
     1021 tgtgtaccct caccaaggac ttaacctctc tggtcccaaa cctctctttc cccacctcac
     1081 agaataggct catcgaaagg cccaggacta gcagtctgaa gaaatgacat caacaagggc
     1141 agggacacag tcaatctggt acccagtgtc acgctgtgtt tgctgaatga gtaagactaa
     1201 attagcttca gcacacttat ttataaaaag tagagggcag gcgcggtggc tcacgcctgt
     1261 aatcccagca ctttgggagg ccgaggcggg cggatcacga ggtcaggaga tcgagaccat
     1321 cctggctaaa acggtgaaac cccatctcta ctaaaaatag taaaaattag ccggacttgg
     1381 tggcgggcgc ctgtagtccc agctactcgg ggggctgagg caggagaatg gcatgaaccc
     1441 gggaggcgga gcttgcagtg agccgagatc gtgccactgc actccagcct gggccacaga
     1501 gcaagactcc gtctcaaaaa agaaaaaaaa aaaaaaaaaa aaaagtagaa atgctaacca
     1561 cctgccaacc ccaacaggtt cctctgacaa tcagatgtaa tgggtgggac aagctatacc
     1621 aatggatgac atcactatct cataacaaaa atatcagtgc cagagagagt attataagga
     1681 aactgacact cagtaaggtt taatgagtaa actagattag caacttcaca ttcactgagt
     1741 gatttcacat ccagtgtggc atctagtcca cattttaagt gtaaatccca ctatgaataa
     1801 cttaaaggaa atcatttcat catttgttct gaacctctgt ttcttcatct gtaaaaagag
     1861 aatgcgggcc gggcgtagcg gctcacacct gtaatctcag cactacggga ggccaaggtg
     1921 ggtggatcac ctgaggtcag gaattcaaga gcagcctgac caacatggtg aaaccccgtc
     1981 tctactaaaa atacagaaat cagccgggcg caatggtgcg tgcctggatc ccagctactg
     2041 gggaggctga ggcaggagaa tcgcttgaac cagggcggca gaggttgcag tgacacgaga
     2101 tggtgccatt gcactccagt ctgggtgaca gggcgagact ctgtctcaaa aaaaaaaaaa
     2161 aaaaaaaaaa gagagaatgt gctccatctc ttctgtttgc cccctccaaa aaacacccta
     2221 ccctctcctc cctgccctgt gtccccgagt atagacctca tgcacaggtt tcctggctct
     2281 ccagcttcca gatgggtctg cccagcagga ggcaccagca gaagtttggt gggaggaaga
     2341 aagagaggtc agggtatttc ttcccccacc tcaatccttg acaggaaact ggggctgctt
     2401 cccttgaaca aagttatcag caggtctcag gtgccctctc cacacaattc agatcacacc
     2461 cttcacccct tccggcccaa agatggacac caggttctgg agttaccagc tatgggatac
     2521 taaaccttca ctcccgattt ccctacccac acctttattg agtttctctc agatcatcct
     2581 aatttaaatg tgccacctat ttcctgctga gatcctggat tatacagtag atatcaccac
     2641 ctcataaggt tacaagtgag agaccatgtt atgactagat gctaggcact gagctatagt
     2701 tactgttaca acaattatat tatgcagaaa ttgttgctcc caatctgcag ataaggaagt
     2761 cgagagggtg agagaaatta agaaattctt acaagcacat acaagagttg aacagctaga
     2821 actgaggcct taacctccag aaccagaaac ctttccattt ctattatcac catcgcggtc
     2881 aatatttttc ttaccacaag tttcatcatc gccgtcattc ctacataaca aaataacact
     2941 ctcttgcgaa tgagtttatt tctactgttg gacgtgtggt taagagtggg agttctggaa
     3001 tgggatcaaa gtacaaggcc tgacttgcag gaagtgttat cttgagcaag aaactttcct
     3061 ccacgagcct cagtttcctc cagtaaaatg gggatagata acagggcttc cttcacaggg
     3121 tcgtggcgag gattcaatga gataacgttt gcaaggcaat gggcaggcag taagcactca
     3181 aatccgacag gagctactgt cacgaaaagc gggtttgcag ccttggcggc tttatcgccg
     3241 ccgaggacta gggaggcggg ccaggacatg gggacccgag gacctgaaag actggaagat
     3301 gcccgctgcc cacccccggg cccacctgct cctccagtct ctcaatctcc agctggtttt
     3361 tctcctcctc ttcgtcatat tcccactcgt actccccggg ggagctctcc gcggaggaag
     3421 ccatggcgta ctcatcccca tcgctctcgc tcacgccttc ctcctgctga tcccacgctg
     3481 gccccatggt cttgtatgtc gcagcggcca cagcccgcga taacaccttc ctccttgtcc
     3541 tagccgcctt aacctcatcc tcctctccgt cagccttggg cccagccttg gactcagcct
     3601 cgggttctga agccgaggtt tcggccgcag tcgccatctt gcgcttctaa tgactctcgg
     3661 gtcttcccgc ggccgccgaa gacccgctga ggcagaagct gcccgcggcg cgcgccttat
     3721 caaaaacccg ttttcttgcc attgaaagag aaactgggaa cttagataac aggaaaatct
     3781 ccacatacac taaattcaca ttattttata ccctgtaaaa gctcccacca gatataaaaa
     3841 ctcattataa tggcatgcgt tccgtcacaa cttcggacag aagttgggtc tttgggcagg
     3901 aagtggaagc catagaggaa gtcatggagc gagagtgatg tctgtagtga agaatttggc
     3961 gccatcttga gaaggtcaaa gtgattcttc gattaaatgc cttacttatc gcctagtgtg
     4021 acctggcgct tgggtttact ctccccagca actgcgcctc aaacgcaaag aaaactgcag
     4081 gtcctcgggg aaggatcgat ttcaccattc aagagaaaaa tccatttccc agattcctcc
     4141 cctttatgta aacgtctggt acctagtaga cgttaaatac acgtgagttt tccggtttta
     4201 taagatcaca tactgcaaac caacagtaaa ttacattaat acgcatttct ttagaaattc
     4261 ttaattgcta ggcactgaca tataaattga gtttgctgtt gttttagaga gaaaaataga
     4321 catattcatt ttttttcaat caggacatgg tattcgtttc cttcttaagc ttcccatttt
     4381 tgaggtagga aagtattggt gtgtgtctct atctctacct tgctccctca ttagcaggct
     4441 taatgggcag gaattatgtc tgttttgctt tccgttggat ccccgggtct agtagagcgc
     4501 cttgacacat agtaggtact cgacacagat gctggcttca tgatgaagca attgtcctcg
     4561 aattaataca aaagggaaga ttcagactca gcgagccggt accattcgtc tagggacaca
     4621 cagccaggaa ggaaccgaac caggattcta acccaggatt acccaagttc gaattctaat
     4681 tgaacataag tccttagcga ccttggacgg acttactaaa ctgccctgaa tctcggcttc
     4741 cttagctgca aaatagggtt aggaaaagtg gactcggtgc tcctctgcgc cgcattcccg
     4801 cagcgggatt tgtgaaagcg aacttgagcc ccacactgca gaagccctga ggtcctgtct
     4861 caaccagaat ccagcaccca ggacaagccc tccagcgact tcagaccttc ccgctcccga
     4921 ccccgcccgc ccccgagagg cgtggtcaag gcggggccag aaggcggacg cgtgcacgga
     4981 gcggtaaagc gcaggcgcaa agcttcggtg acgtcagaga ggcgcgctcc cagctcggag
     5041 ccgactcgca gacgcgcccc gcccctcggc gtcgctctgg actggcgcag gcgcaagccg
     5101 gcaagatggc ggcggctggg gctttccgtc tgaggcgggc ggcatcggct ctgctgctgc
     5161 ggagcccccg cctgcccgcc cgggagctgt cggccccggc ccgactctat cacaagaagg
     5221 tagggacaaa agagggacgc gcggaatgcc gactcagcgg aggcctgggc tggaggggcg
     5281 gccgcggggt tctgcgcagc taggactggg agctgtcccc tcccacgtct ttgccctgac
     5341 tcgctttccc ttgctgcgca gtgaggctca ctgcaactga taaacaacag ttaccgctca
     5401 tcgggcggcg acttccaggg ggccccgccg ctggccgcga cttcgtgcgt cccaatttta
     5461 aattcgccaa cagcccagga ggcagggtcc tgttgggact tgtctttctg agtccaggga
     5521 cagacacacc cccggagcgg gctccggctt cagccactcc gctgccctgg ccagatgacc
     5581 ttgggctagt cactgcgcct ctctgaacct gtttccccag gtgtaaatgg ggggctctca
     5641 gctgtccctt acaaaggata ctgtgcgtgg agtcctggca tggttcctgg cacataggcc
     5701 ccagcacgag gagaccgttt ctgttactgc tttaggagtg cataggggag tcaggcttgt
     5761 aaccaacatg cgtaatgttt ttgttttgtt tggggggttt tttggcgggg aaggagggat
     5821 agattcatag tctgcagccc cttgctgtct ggtggcacaa agtcccccag acgtgagact
     5881 cccactcgag aaacaactaa agaatgccat aaatcaacgt ggcacaaaag gcccctacat
     5941 tagatactat cctgaggtcc cttttacttg gagtcaaaat ccttagtcag atggggggaa
     6001 aaggggactg gaagatcggc gtgcttacta ctaaccagta accaaacctc aaggttatta
     6061 aggccttctg tgtgccagtt cgaatggatg tttattgtga tctggcttct gccctttctc
     6121 caagggcttc ttcactcctc cccctcccgg gggtgtgttt tgttgagggt acaccctgaa
     6181 gaaacttgga ctagcagcct ttcagcagcc agggtgcgct gctgcaccag ggtgatgaca
     6241 ggctgtgaaa tacggtaatg gcactgtttt tattttaaaa gacacataaa cgtacacatt
     6301 ccatagcatt gttccctgtg taacagtcac cttaaggctt ctaagaaagc tttccctccc
     6361 tgggccatgg ttatttttag aatttttaaa tagtaatcat cctttgagga tggattttat
     6421 ttgaaaataa caaaactgct gtttgagccc aagtctggtg atgtaggtgg gtgaaagtca
     6481 agtatttttg taaaaatcct atggaactaa gacatgattt cactgatttt tttttcttct
     6541 aggtatctca aatctgtgaa gtattgtaga ggagacacaa aaggaattgg gggtcacaaa
     6601 tggttctcat tgacatgagt gtagaccttt ctactcaggt gaaatttggt atttagtgat
     6661 tgcctgccag gttcaagatg ctgaccgagg agcttaccat caaaccagag accagtacca
     6721 atagagagtg aacatgattt atcttaaccc tctcatttta ggttgttgat cattatgaaa
     6781 atcctagaaa cgtggggtcc cttgacaaga catctaaaaa tgttggaact ggactggtgg
     6841 gggctccagc atgtggtgac gtaatgaaat tacaggtatg gctagtcttt tttaatagtg
     6901 ataacaataa tccctttaag tttacaaagc acttgcgcat ttcacttggt ctccatcttt
     6961 attcctgtga gatctccaag catttcactt ggtctccatt cctgtgagat gggatgagtc
     7021 catgttagat atgactggag cagggcctca atcgtagctc tcctgctagg ctagtgtact
     7081 atgccaactt tttccaaaat agaaaagtaa tctcattttt gtactcactg tatcagttta
     7141 aattctgact tcagccaact aaagagtttt gtgaatttta ctgatcaaag gaaaatccca
     7201 gtgagctagc agtccccaat gaaacaagaa acacagtaaa ttaaacctgt ccccagattg
     7261 ggggaaacat gaaaatagtg tctagtgctt tgggtaaact gtagttgtag caccaatctg
     7321 ctgcttcatg gtgagtgggc agcttgccag aggtcttcat acctatcttg gaatacagaa
     7381 acaaaacagg aggaaaccac taagtgtaat ctgctgccca agaaaaaagt attaaccaga
     7441 gacctttatt gtggactctg tcagtgttta aagaggccag attgccccag cagctgtgag
     7501 cagacttcca caaatagaag ttcatagcca aaatgcaggc cagagtcaca aaacaaaaga
     7561 atattggagt ggagggacat atttttcagc tgatctttgt cagttgggcc tggatagttg
     7621 tccctgcatt tcacttttca tcactgagct ctttgaaaca aggcaaagtc agtaattaat
     7681 gccatcactt agtgtggaaa gcaagcccaa agcccttggg gaaggccctg gtgaaccttc
     7741 gtgagtgcca ggttccagag ggtggtccca ggactcacca cttaactctt gtctcttttc
     7801 tagattcaag tggatgaaaa ggggaagatt gtggatgcta ggtttaaaac atttggctgt
     7861 ggttccgcaa ttgcctccag ctcattagcc actgaatggg tgaaaggaaa gacggtaagg
     7921 tggctcacaa atctaatggg tcaaaaacaa gtaaccatga ctttttttta atattctaaa
     7981 tttttaaaat ttctcctatg cagatgttga ttatattatc atttcttcaa attgggaatt
     8041 atggatcatt ctactaggtg ttgtttgggt ttttttcttg ttgatcattt ttattttttt
     8101 gtttgtttgg gtgttaatta catataaaaa agatcctcac ctgtccctct aacaaaatag
     8161 aatttaaaag aaatctttgg ctttctctaa ggttaccagt gctcttataa tttctcaagt
     8221 cagagagttg ttataaggta gttattttct tgtttatttc ctctcatgtt tcaggaaggg
     8281 ttctaggtgg ctttcaagaa ttggtgaaat aaactagcct gtgttaaaag agggattaaa
     8341 taatcaaaaa gacagcaagg gtgggggcaa agtgaacaac gaaatcagaa cagtgatcca
     8401 ggtggctgat cgcaagccct ctaaaggcag agataataaa gagctagaac ttctttttca
     8461 tccctttgtc tcccaagtgt ctttccctgg tagctgcaga ggtcaaaggt cccaaacaca
     8521 gtgaagagct ggactttcta aaatccagtt gctgtcaaaa cctctcagaa aagccaacca
     8581 gcaaggcact catctttgct gccccaaggg accaggttca gggagctgag tcacagagga
     8641 gcatgcttgg aagctggcca gctccacagc agagcagttt gccaggccac gtgccacctg
     8701 cttcctgtgg ctcacggcct tctggctggc aagcccctgt gggccaggaa gctcagacct
     8761 aacctgctgt ggcaggaggt agctctgaag tgatttgtca ggaactgtcc tcaggtgaag
     8821 ggagaaatga gacaaggcac ttttgctccc agaacctggc ccttagggga ctgtgaattg
     8881 tgatcagaaa atgggagaga ggacatttct ttaaccttga gatctcccat ctgagtttca
     8941 ggagcagaac ctgaatcaac caagaagggt tagcagaatt gggaaactga atgatagaca
     9001 tagtcaaaga gtctggctgt tgggaaatct ggttttctgt aaggcagtgg ggcactgttc
     9061 tacatgggca aggatctgcc tgcctcacat tatcccccag ggctgtcaac cagaccccag
     9121 gcatcctctt tagttgatct ggaggagatg ctcctatagg caaaggggac accaaagaga
     9181 gcattcggcc tgactcggct gtgccactgc cactgtgcta cttacctgaa atcttcccaa
     9241 cctctctgat gccattcggc acttctagtc aaaaggattt aggctaacat ttggtatgag
     9301 gacatcggag aagctgatat tcacaaaacc agcataggaa atcactacct tttaaggaag
     9361 agattcctgt tacaggccac aagcagatcc ctaagagact tctcacaggt tccactcctg
     9421 acttagagaa gtgtctgggc tgtctttgct tacccaagcc aggcagtgca gctgtgtata
     9481 cttcatgctt gagaatccca gctgcagctt tgataaagtg ggagtcctga gaagaccctt
     9541 agccgtttga gttattaaac agaaatcatc cccaccaacc ctgagagcct ctttggcctc
     9601 ccttttttat tggctggccc tcacaagata aagtgttgct aaaactgccc atctttccat
     9661 tatgcctctc aggtggagga agccttgact atcaaaaaca cagatatcgc caaggagctc
     9721 tgccttcctc ccgtgaaact gcactgctcc agtaagtctc tgctctccat accagtcagc
     9781 tgggacattt ggcagtaatt tcaacttggt ttgcaacagt ccttttagat catggagccc
     9841 acgtttgtaa ccctcagaat tagagctcat gagtctgtcc ttataacctg cagagggtta
     9901 gagcccccat ggtctcacat tcatccctaa gagaatcatg ccagaaggag gtatgcacca
     9961 gccatcatac tgagcacttc atgggcgtaa tttctaaacc tcacaaatat ccttgagtgc
    10021 acagtagatg tcattacttc cctcttatgg atgaggaagc taaggcttgg gttgagacgc
    10081 ccacatcaca tggctaataa gtggaagagc cagaatttaa gctccaatct ttgatttcag
    10141 aatctgtgct gtttccagca gaggagaaaa ctcagctttc gccataatcc tgtttcctgt
    10201 gtatttcttc acttcctgtc tggatggtat tcctgtcggg gtctgcatct gtatatatgg
    10261 aacaactaag cccagttgta caatgtcccc ctccctgcta tcctaaaaaa aagcccagat
    10321 gccttaagac ttgtacttgg ctttccagtt tggtctctgt attaaatcta atgctttttc
    10381 catcatttct taaccttctc agggaaagaa ggaatgagaa acattagcct taatgcatcg
    10441 atggaggttt actaaccaaa ttagttaaaa atcagcagag agtcaggcct cttgccaagg
    10501 taatactcac agcagaagag ccaggtgccg gggcagacac actaactcat tcttcaggaa
    10561 gcctggtcag acctaagttc tttccacttg atctggaatt ttaagtaccc ataaagaaag
    10621 gtcatcactt gtaaacattt tcacatggtt tcaggaaatc cccagccctt ttattaggcc
    10681 tttttaggta ctgaaacctt tagctgatgt tctctgttat ttgcttgctt tctgctgtca
    10741 ttccagctct ctcagttttt attttcccca tagcctcact ttgaatattg actcctaaat
    10801 aaaagtggtc aaactctcga tcactagagg gtgatgtggc aaatgccatc ccatcaacag
    10861 attgacatga tcttttttcc aaagggcatg tcaacttttt tatcatgaca agattttgtc
    10921 caaagctaga ctttgatggg agcaggcaag aagtaacatt tcctgtgtcc ctactatgtg
    10981 tcagacatct tctgtaagtc cccacactat cctggcaaga aaagcatgat tatcccagtt
    11041 ctatagaaga gaaagtaggg tcaaagaggc taaggaacta gcctgggatc acagattttt
    11101 aaccctagtc tgtctccagg atcacccgca ggagtaactc agctcaggaa gcagctgctg
    11161 acgtgcccag caactcctca ccccagcttt ctggcttggt tactccatta gtccccacca
    11221 gcaccacttc ctcccagctc ttaaagattc tattcccaag tccatttctt tcacatctag
    11281 aaacttaggc ttctttcctt ccgttacttc cagtgctggc tgaagatgca atcaaggccg
    11341 ccctggctga ttacaaattg aaacaagaac ccaaaaaagg agaggcagag aagaaatgag
    11401 ccctccctcg gcgaagcctc cagcaggcca caccagctgt ttcccacctg ctgtgcagtc
    11461 accttagatg ttcagaagcc gcttcctctc cactgaagag ctatgagata cgcacaatac
    11521 ttgctgttca cgttatgact ctcatgcaag caaaatacac agtttcattg ttctgaatcc
    11581 tgtggtttct ttcagcccac ttttatcgcc ttaacctagt taatgtatat tttgaattgt
    11641 gtgtatgacc tcagaactga aattgataat gaagttgcaa gttttgatag cccgtgaagt
    11701 gcataagtat ctaattttac ctgaattgat ttggggggaa attaccagta gaatgccttg
    11761 gtctgaatat ttgatagaac caattgttgt acataaaaca gattgcgcat atatatatat
    11821 gtataaaaaa taataaaata atggaagatg atggtgttct ctagtaagcc ttgtctcttg
    11881 ggcccatcat tcaccctgaa gtggtgccca aagccccttg gggttcccag aggttggacc
    11941 gcagtgacat acacagctct ccaagcaaac aaagacaaat atacgtaata ttttttggaa
    12001 caaggatgaa aggagatgat tatcgcttgt cattgttctt tgtgtgatag tagttgaaag
    12061 ctcaaagtaa gtcttgaaga ttctttctgt aatttcactg gttgctcaaa tctaaaaagc
    12121 attagcttgg caccctaaag cggtagacca gatacatgaa gagcacctcg ggaatgagtt
    12181 taaaatgcgg atttctaggc ccaagtttct gacttctgtc tgggcaggta attccagagc
    12241 ccctgacttt taagaacctc ttgggttttt tgtggtcgta gatgagccaa actttaggga
    12301 agaaacttct gaatgctgtg ttctgcatag atgtagtatc ttaagtggtt cattctgaac
    12361 tatctgtacc tgcatagtac acctaaggtt gtttaaaaaa cattcatcca gccgggcgca
    12421 gtggctcaca cctgtaatcc cagcactttg ggaggccaag gcgggtggat cacgaggtca
    12481 agagttcaag accagcctgg ccaaggtagt gaaaccccat ctctactaaa attacaaaaa
    12541 ttagccaggc atggcggcac gcacctgtaa tcccagctgc tcgggaggct gaggcaggag
    12601 aatcacttga cctgggaagt ggaggtagca gtgagccaag atcacaccag tgcactccag
    12661 cctgggagac agagcaagac tccgtctcaa agccaaacaa acaaacattc atccctggct
    12721 tgggcataag tctaagcacg ggccctccta ccctgatgtc tccctatttt tagctaccca
    12781 tagtcatgca aatctcaata aaggatgccc tatcttctag tgaaaatggg ttattgaaat
    12841 attgactgcc atagtctcaa atgttcagct tcaaaagtaa gatgtgtttg ttttttctgg
    12901 tggtggtttt tttgttcagg tataggctgg ctgcctctta aatatacctc ccttgttttt
    12961 tttgttgttt tttgtttttt tgttttaatg ctctgggttc tggtggaggg cacagaactt
    13021 caaagactgt tccttctgta gtctgtgaag gcagccacag accagggcct ttataggaat
    13081 ctcaaattag aaccctgggt agaaccatgt aaaattgtcc tgtgtggcat gttctgcaat
    13141 ttaattcaca gtccctctag actgagcttg tctctccctt ctttattaca tgtggcacca
    13201 ccacaattcc ccaccacttt tctttgtgat ttttttaatt taaatgagac atttctgtcc
    13261 cagtgaacat cctcagagtt gaacatcagg aggagcttat aaacaaagca atattcccag
    13321 aagagcccaa gtctctaaac gtggttgtac tgctaaaaca aatggatatt ttttaaattc
    13381 acattaaaga cactctttcc ccaaacaaat ctagtttgag ccacatgagg gcatcatgtg
    13441 cccttcagtg aactcaagtc taggggtttt tgcagcctcc aaataggtct tagcatctct
    13501 aaataaacct gtccatggaa aacctccaca gataagttaa aatggtctgt caagcacctg
    13561 tgctctgttc caggccctta catctgtaat cctgttaatt ctcatgacag ctgcctgcag
    13621 tgggcattga ttcaaacaag gacactggct caagaagcca actgaccctc aggccaactg
    13681 gcttgatctg agtgacccaa agcccattct tctgcctcac ccctcctggc agaacacacc
    13741 agggattcaa actgcacatc agaggctcac ctgtgccttg aacattcaat gaagaagctg
    13801 aaccaacaca ggttgagcct gatgcattct cttggccaac tggctgccaa gcaccatggc
    13861 cctcacg
//

