LOCUS       NG_008674              30301 bp    DNA     linear   PRI 04-MAR-2010
DEFINITION  Homo sapiens collagen, type VI, alpha 1 (COL6A1) on chromosome 21.
ACCESSION   NG_008674
VERSION     NG_008674.1  GI:208879425
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Johan den Dunnen. The reference sequence was
            derived from AJ011932.1 and AP001479.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The collagens are a superfamily of proteins that play a
            role in maintaining the integrity of various tissues. Collagens are
            extracellular matrix proteins and have a triple-helical domain as
            their common structural element. Collagen VI is a major structural
            component of microfibrils. The basic structural unit of collagen VI
            is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI)
            chains. The alpha2(VI) and alpha3(VI) chains are encoded by the
            COL6A2 and COL6A3 genes, respectively. The protein encoded by this
            gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain).
            Mutations in the genes that code for the collagen VI subunits
            result in the autosomal dominant disorder, Bethlem myopathy.
            [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14799             AJ011932.1         23020-37818
            14800-30301         AP001479.1         1-15502
FEATURES             Location/Qualifiers
     source          1..30301
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            5001..28301
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /note="collagen, type VI, alpha 1"
                     /db_xref="GeneID:1291"
                     /db_xref="HGNC:2211"
                     /db_xref="MIM:120220"
     mRNA            join(5001..5199,5886..6015,7521..7721,9778..9937,
                     10196..10324,10407..10427,10751..10771,10862..10906,
                     12336..12389,12860..12904,13004..13030,13510..13536,
                     13630..13674,14025..14078,14231..14293,15262..15324,
                     15416..15469,15615..15650,16000..16062,17419..17481,
                     20673..20735,20952..21014,21373..21423,21650..21685,
                     22149..22211,22405..22470,22909..22944,23583..23619,
                     24011..24019,24505..24638,25213..25322,25470..25653,
                     25779..25962,26372..26401,26643..28301)
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /product="collagen, type VI, alpha 1"
                     /transcript_id="NM_001848.2"
                     /db_xref="GI:87196338"
                     /db_xref="GeneID:1291"
                     /db_xref="HGNC:2211"
                     /db_xref="MIM:120220"
     exon            5001..5199
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             join(5103..5199,5886..6015,7521..7721,9778..9937,
                     10196..10324,10407..10427,10751..10771,10862..10906,
                     12336..12389,12860..12904,13004..13030,13510..13536,
                     13630..13674,14025..14078,14231..14293,15262..15324,
                     15416..15469,15615..15650,16000..16062,17419..17481,
                     20673..20735,20952..21014,21373..21423,21650..21685,
                     22149..22211,22405..22470,22909..22944,23583..23619,
                     24011..24019,24505..24638,25213..25322,25470..25653,
                     25779..25962,26372..26401,26643..27265)
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /note="collagen VI, alpha-1 polypeptide; alpha 1 (VI)
                     chain (61 AA); collagen alpha-1(VI) chain"
                     /codon_start=1
                     /product="collagen alpha-1(VI) chain precursor"
                     /protein_id="NP_001839.2"
                     /db_xref="GI:87196339"
                     /db_xref="CCDS:CCDS13727.1"
                     /db_xref="GeneID:1291"
                     /db_xref="HGNC:2211"
                     /db_xref="MIM:120220"
     exon            5886..6015
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     exon            7521..7721
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            9778..9937
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            10196..10324
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            10407..10427
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     exon            10751..10771
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=7
     exon            10862..10906
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=8
     STS             10900..11944
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /standard_name="STS_CEB250"
                     /db_xref="UniSTS:255254"
     exon            12336..12389
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=9
     exon            12860..12904
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=10
     exon            13004..13030
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=11
     exon            13510..13536
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=12
     exon            13630..13674
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=13
     exon            14025..14078
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=14
     exon            14231..14293
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=15
     exon            15262..15324
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=16
     exon            15416..15469
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=17
     exon            15615..15650
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=18
     exon            16000..16062
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=19
     exon            17419..17481
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=20
     exon            20673..20735
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=21
     exon            20952..21014
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=22
     exon            21373..21423
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=23
     exon            21650..21685
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=24
     exon            22149..22211
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=25
     exon            22405..22470
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=26
     exon            22909..22944
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=27
     exon            23583..23619
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=28
     exon            24011..24019
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=29
     exon            24505..24638
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=30
     exon            25213..25322
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=31
     exon            25470..25653
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=32
     exon            25779..25962
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=33
     exon            26372..26401
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=34
     exon            26643..28301
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /inference="alignment:Splign:1.39.8"
                     /number=35
     STS             27282..27593
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /standard_name="RH75955"
                     /db_xref="UniSTS:88836"
     STS             27282..27551
                     /gene="COL6A1"
                     /gene_synonym="OPLL"
                     /standard_name="RH75955"
                     /db_xref="UniSTS:88836"
     STS             27794..28328
                     /standard_name="COL6A1_3124"
                     /db_xref="UniSTS:462114"
     STS             29071..29717
                     /standard_name="STS_CEB292"
                     /db_xref="UniSTS:255278"
ORIGIN      
        1 ggggcctggg ccagcagccc tggggctccc accagccacc agcagcactg agtctcctct
       61 gcaactttcc ctgtggacaa aggcagtttc ctgggatggt ctttccttcc cgttccacca
      121 cttttatggg tttaagaaaa ccactaacac aggacagcgg tggataattc cccttttccc
      181 cgcgctgacg tttggaggca ccagggctcc tcaaggtgga ctggggggct cctctccctg
      241 aacgcagggt cctgatgggg gtgggggtgg gggtgggggt ggagggcagg caggttccag
      301 aaacagccct gccctcccct gcctcccggg acagcttcct ccaccaagcc cacctcatgc
      361 tccatcctca tcccctctta gccaggtcct gctggaagag gaggctcggg tccacccgca
      421 ggagtcagag aggccctgcc agggacactg cacattcaag gccctctcct ccatccttct
      481 tcctctccct cctcccaccc tctccctcct cccaccccct ctcccctcct cccattctct
      541 ccctcctccc actctctccc ttctcccacc ctctcccttc ccacacctgg agactcagat
      601 ccccccaggg ctgtggacga ctggcacagt ggggtaagtc ctgctcccca cagctgcttc
      661 tgggatccca gactgggccc agagtcccca tccacagaag ggccggcagg cctgagaaag
      721 gacagccagg tcgccaggga ggggatgtgg ctcgccccct tcttcccttt ctctggaagt
      781 gcatttacct ccccccacac acaggcgggg ttgcagggcc cttcccagcc agaccctgca
      841 gtgcagctct ctgggaggcc ccccagggca gtggtttcct ggctctgtgc ttcctaggat
      901 cctggaagcc gactgggctg gggttggggg gtggagcccc atgggagaag gatctcctgc
      961 aggaatggcc tggatggggg cttgggggtg gacatgtgcc agagacacct gggtaacttc
     1021 aggagagagg agggaggggg agagaggagg gagggggaga gaggagggag ggggagagag
     1081 gagggagggg gagagaggag ggagggggag agggggggag agaggaggga ggaggagaat
     1141 aggggatggg agagaggagg gagacggtga aggggagagt agggagccgg agaggagaat
     1201 gaggacaggg gagaagaggg agggggagat gaggaaaggg ggaggggagc aagtgtgaga
     1261 ggagggaggg ggaaaggagg gaagggggag aggaggggac aggagagagg aagaaggggg
     1321 agaggagtga gtgtgagagg agggaggggg agagagggga aaagggggag aggagggagg
     1381 gggagaggag ggaaggggga gaggagtgag catgagagga gggaggggga gagaagtgag
     1441 cgtgagagga gggaggggga gaggggacag gagagaggag ggagggagac aggagtgagc
     1501 gtgagaggag ggagggggag aggagtgagc atgagaggag ggaggcggag aggaggggac
     1561 aggagagagg agggaggggg acaggagtga gcgtgagagg aaggaggggg agaggaggga
     1621 agagggagag gagtgagcat gagaggaggg agagggagag gactgagcgt gagaggaggg
     1681 agggggagag aagagaaaag agggagcaaa ggggacagga gagaggaggg ggggagcgga
     1741 gggagctcac ccgctgtggg tggggcaggt tgtggaaatc agccccatga caacagtaag
     1801 ctcagccagg actgggattc aggatgtttt attttcatgc tttatgtggt tttcatgttc
     1861 tccctgagac ataagcatca cttacaatca gaaaagatcc ctgatgaaag tgcatgaagg
     1921 aacacaaagc aggcgactgc acgtctatga acacgctcac ggtacggtgc acagagcagg
     1981 cgacagcacg tctataaaca cacttatagc acggtggcca cggtggctca cgcctgtcat
     2041 cccagcactt tgggaggccg aggagggcgg atcacctgag gtcaggagtt tgagaccagc
     2101 ctggctaaca tggcgaaacc ctacctctac taaaaataca aaaattagct gggcatggtg
     2161 gcatgtgcct gtagttccag ctacttggga ggctgaggca ggagaatcac ttgaacccgg
     2221 gaggcggagg ttgcagtgag ccgagattgt gccactgcac tccagcctgg gcgacagagc
     2281 aagactccat ctaaaaaaaa gaaaaacgct taagcagaaa cacactgaag tattagctct
     2341 gaatcccact cggtagtgaa actagatgtt gctttatgat tttaaaaaat tcgctatgat
     2401 gaacatgtat cttcttcata agagaaagag tcaagtttac tctgagtcat cattgcagat
     2461 ttcctgtgaa gcagaggcac ctctgggccc cacccaggcc tgggaccgcc ctgagcctga
     2521 gcccctcaca cagtgcggcc ccagccctgc ctcggagaag cccaggccag gatgaagcct
     2581 gggaccgggg gaggagtcgg accgcggccc tggagctcag gatgctgcag cctggggtgt
     2641 cggcgttatt cccacgcatc tccacagctc ccgccgcacc caccccgcgg acctgctggc
     2701 ggagccggtg gtatactgtg aactgactta tgaaaccacc tctgcaaggc aaaacaggcc
     2761 attggccact gggccccgtg aacctgtccc tgggcgtccg catctcttcc atcttacaga
     2821 ccgtgtgtca gccacctgct gctgtgtgcc tgtggtggga ccctcactgc agggaatgct
     2881 gcattcttgg tgtttgctta cacaacgtgt tcctatttcc tttcccaaat ctgcaagcac
     2941 tccttgcaga taaaacagct cagactggga gaggccaaga gaacacggag gtcctgaagc
     3001 cccctgtgct tgagtcagga gcccagaggc tggtgccaca gctccaagca ggcagcacca
     3061 aacctcagca cccacagcca cagtgtggat gacatcagtg gcaggtaaat tgactgtaca
     3121 gtaagtgtac aaggccaggc acggtggctc atgcctgtaa tcccagcact ttcggaggcc
     3181 gaggcaggag gaccacttga gtccaggagt tcgagaccag cctgggcaac atcgtgagac
     3241 ccccatctct acaaaacata caaaattagc tgggtatggt ggcacatgcc tgtgatccca
     3301 gctactcggg aggctgaggt ggagggatca cctgaaccca ggagactgag gctgcagtga
     3361 gctgtgatga ggccactacg ttccagcctg gatgacagag tgagcccctt agataataat
     3421 aataataata aggaggagga ggaggaggag gaggaggaaa agaaggagaa gtactttaca
     3481 acttctgtaa cgtaggtgtg gggaaaatat tgaaggcaat ccaaaaacag tcactgtgga
     3541 gttgtggaat taagtatcaa ttttaaaggt tttttcaaat gtttctttaa catggttttt
     3601 ggtatgaaca atttgtgtac gttttaaaat tataagacat ttaggctggt gttaggcaag
     3661 tctcagcagc tccagctttg ggaaagctct tctgggacct tctgtgggcc agggatgcat
     3721 ctggccacat ctggagccca cccccaggtg atatcaggga cagcccctct ctcctctctc
     3781 tgtctctctt tctgtctctc tgtctctgtc tctctgtctc tgtctctccg tctctgtctg
     3841 tctctcctct ctgtctctct ctgtctctgt ctctctgtct ctgtctttgt ctctctctgt
     3901 ctctcctctc tctgtgtctc tgtctctgtc tctctctctg tctctctctg tctgtctctc
     3961 tgtctctctc tgtctctgtc tctctctgtc tgtctctgtc tctcctctgt ctctctgtgt
     4021 ctgtctctct gtctctgtct ttctgtctct ctctcactgt ctctgtctct ctctgtctct
     4081 ctgtctctgt gtctctctgt ctctgtctct cactgtctct ctctctgtct ctgtctctct
     4141 gtctctctgt ctctctgtgt ctctctgtct ctgtctctct gtctctgtct ctcctctgtc
     4201 tctctgtgtc tctctctgtc tttctgtctc tctgtctctc tctgtctctg tctctctctc
     4261 tgtctctgtc tctcctctgt ctgtgtctct gtctgtctct ctgtctctgt ctctctgtct
     4321 ctctctcact gtctctctct gtctctctgt ctctgtctct ctgtctccac acacagcata
     4381 tataacaact atattgtgag caactttgtc ttcccacggt acaaactgaa atatctttgg
     4441 caaatacgta tccgactata ctgtgaagaa atattgacgt gaaaaaagaa cgcggagatc
     4501 tgataaagca acaattcagc tcacggcgag gtcctctgca ggaggcggtt ggtgggaaga
     4561 ggcgagtgag cctgcccgtg cgtcccgcat ggagacgtct ggattggaaa ctaccgaaag
     4621 atgtttcaag gaactctccc tgggtgacac gctggttttc agacgtttga ttcagctgct
     4681 gcagtttcct cctccctgac acgggaactg aactgcaggc cgcggcgagc cagccaggga
     4741 aaccgccttc tccctgggct cggagctgct gccggttctg gagggagaga ccccagcaag
     4801 gaggtggtga ctcatgggcc gctcctcccc gccccgcccc gcccctcccc tcccgccccg
     4861 cccctcccct cccgcccctc ccctctcctc ccgcccctcc cctcccctcc cctctcctcc
     4921 cgccccgccc ctcccctccc ctcccgcccc tcccctcccc tcccgcccct ctcgccccgc
     4981 ccctcccctc cttgccctcc gctctcactc tggctgggag cagaaggcag cctcggtctc
     5041 tgggcggcgg cggcggccca ctctgccctg gccgcgctgt gtggtgaccg caggccccag
     5101 acatgagggc ggcccgtgct ctgctgcccc tgctgctgca ggcctgctgg acagccgcgc
     5161 aggatgagcc ggagaccccg agggccgtgg ccttccaggg tgagtggtgg cttggggtgc
     5221 aggctccaga ccccccgctc tttgctgccg gccagggcca gatgcgcggg gtcccctccc
     5281 acgcgtggaa ctgcagactg ggggcctgga gcccctgaac cccactcccc gctcggggcg
     5341 gctgcagcgc ccagctctgc cccaccgggc cttggccggg gcccctagag gctcagcatt
     5401 cagcattctc agcggggccg gaccgcaggc agctcgggag gggctccctg gcgaggggga
     5461 gctggtgcgg ggctgtctcg gcgccccgtg aatccgtttg acccctcacc tggcagtgag
     5521 tccagacgca cggccccccc gacccccgtt ctagaagaag tcgtgcgctg ctggttctga
     5581 atccagcgag aaaccttccc gtgaggtctc acttgtccgg tcccgtgccg gggacgccct
     5641 gcccttcggg ggaggttgtg aaggtttctg actcccctcg aggcacagga gcggtttggg
     5701 gtctctcact ccaccccctc cccaccgtcc ccaccgaggg acgtcctgct gccttttccc
     5761 gggagagcct ctccgggccc ggggctctgt gctgcaggcg ctgggctggc cgggagggca
     5821 ggcccagcag agactcgggg aatggggcga gagcttgaag gcccctctcc tccatcttcg
     5881 gccagactgc cccgtggacc tgttctttgt gctggacacc tctgagagcg tggccctgag
     5941 gctgaagccc tacggggccc tcgtggacaa agtcaagtcc ttcaccaagc gcttcatcga
     6001 caacctgagg gacaggtagg agggacgccc cgtgaccttc ctcctgtgct tctgggcctc
     6061 ttggagggag gggtgggggc ccaggggaac acgggtgcga cggcctcaac ctcctaaggt
     6121 tgggcgagcg ttgccctgac cggggcccct cccggcgccc tccagagtga ggccggggcc
     6181 ctttccggcg ccctccagag tgagctggtc tgagcctctc ccagcgcctt ccagagtgag
     6241 ctggtttgag accctgctcg cgggggtggc acctgttcag cagggccgag gtgacagtga
     6301 ggctgagatg tagggaagag aggctcccgc aggctgaccg agagggctca gcgcactggc
     6361 ccagacacgc agtcctgcct ggtgcgcggg agcccctcac taaccacctg gaccctggtt
     6421 tgttccgtgg gcagtgagag cctctacctg ggtcctggat cccacgttct gaaggtcccc
     6481 gactcgggag ccaggagggg tgtcgctctg cagccccagg gcccccaggc ttggttctgg
     6541 gcttgggaca cggcaccctc tgctccacgt tcctccatct gtgcgtgtgg ctgaggacag
     6601 accgggggga gaggggagtc ggtcctgtgg gtgcacaggg ccgctgaggg gggggcatgt
     6661 agaacggggc tcccccactg agacgggtcc tggcagtggg gacacagctt agccggcgta
     6721 ggaacccccg tcctccttga ccctgctgac tggccgctgg gccggagcct cccgccacca
     6781 gaaggggcac agtcagaggc tgccggtaac agcagggtgg accttccagc ccacaccgtg
     6841 cccagcagga gccattggta ccaggaaccc tgagcttagt ggacatggcc aggcccgtgc
     6901 ggcagtgttt gggggggggt ctggctgtgg atggcaccgg ggaggggcgg ccgcgtggcc
     6961 cagcgtcccc cgagtcgccc ttgttgcctt tactcagtct ccccatgact cagtttccca
     7021 cctgtgaaat ggggcggagt catccccatg tcgctgccac tggattcctg caggcgccgt
     7081 ggtcactctg ctgaatggat gggagggtgg gtggggcaga ggtgggccca ccccaggctg
     7141 gggcagagca gacccctgag agcctcaggc tcaggtgctc agagggcagc gagggggctg
     7201 ctcagatccc cggggtgcct ccttccccca ctgtcatgct gccccactgc aggcccaagg
     7261 accccacccc agcagggcca cacactcagg gctcctggtc tgagggcctg agggatcggg
     7321 gcgcaggtcg cttgctggcc acacccgcct gcacagcctt ccaggagggc cggcctcagg
     7381 gccacagggc aagtccagct gtgtgtcagc cacggccagg gtggggcagc ctgtccatct
     7441 gggtgacgtc gcgccctggg acgggtagcg atggcgccag gggccgcccg cctcacgccc
     7501 gccgtgcctg ttcctggcag gtactaccgc tgtgaccgaa acctggtgtg gaacgcaggc
     7561 gcgctgcact acagtgacga ggtggagatc atccaaggcc tcacgcgcat gcctggcggc
     7621 cgcgacgcac tcaaaagcag cgtggacgcg gtcaagtact ttgggaaggg cacctacacc
     7681 gactgcgcta tcaagaaggg gctggagcag ctcctcgtgg ggtgagtggc ccccagcctc
     7741 ctgcccacgc cagttctcac gcgtggtacc cagcctgggc tggggttggc ctggggtccc
     7801 tgtgcggctt cagctgcagc ctccctgttc tcttggaggc tgcacggcct ccctgaccca
     7861 ctttgtgggc aggaaagaga cggagacaga cagagacaga gagaaacaga aacagggaga
     7921 aacagacaca gagagagaca gagacagaga gagatagaga cagagacaga gagagacaga
     7981 gacaaagagt gacagaggga ccaagacagg cagacagaga caaacagaga cagagacaga
     8041 gacacagaga gagacacaga gagacagaga cgggaacaga gacaggcaga cagagacaga
     8101 gagagacaga gacagaaaca gagacagagg gacagagaca ggcagagaga gacagagaga
     8161 cagagacaga gacagacaaa cagagacaga gagacagaaa cagggacaga gacagaaaga
     8221 gagagagaca gagggaaaca gagagagaca gagacagata gaaaaagaca gaggcagaga
     8281 gaagcagaga cagagaaaca aagacagtca gagacagaca gagacagaga cagaaacaga
     8341 gacagagaga cagagacaga ggggcagaga caggcagaca gagagacaga gacagagaca
     8401 gcgaaacaga gacagaaaca tacagagaca gagagacaga gagaagcaga gacagacaga
     8461 ggcagagaga cagagagaag cagagacagg gacagagaca gagacagaaa tagagagata
     8521 gagacagagg gacagagaca gagagataga gacagagagg gagacagaga gatagaagca
     8581 gagagagaga gacaaagaca gaggcagaga gacagagaga gaagcacaga cagagacaga
     8641 cagagagaca gggacagaca gagacagaga gaccggaaac agaggcagag agactgagag
     8701 actgagagag acggggtggt tttccccaca gcatcaacac caagcagggc taggatcact
     8761 gaaacagact catcagaccc gaagcatgcg ctttctcggg gtttttctgg actgaggggt
     8821 ttcctctcat cccagtgtcc agctgtgggg acgcaggggc cgcaagcccc ggagtgtcca
     8881 gaggggaacg tggcctcccc acacccagcc cttcacgagg cctcaggatc ccagtggggg
     8941 tacccgaggc tgccctgtcc agccaggcgg tgcggggggt ttggggagag cctctccccg
     9001 aggtcggtct cagagggcca catggccggt gtgggccgga cattcccttt ccaatggttg
     9061 tgcccacttc cctccagagt tggtgccaag ctgggacctg ggggacttgg agtctcagga
     9121 agtcgtccgc tgtctgcagg gggtgcatgg gggatgtggc cacacacgtc agagtgcggc
     9181 cccctgtgga agccacagac agacacgact cccctaaatg agctcgccct tctggccgag
     9241 atgctcagcg tccccagcag gctgcccgac tgccctgcga tactgccctc cttcctgctg
     9301 ctcccacttt ccctttcggg gggttggatt tggggcattc agggatcgcc ctgttgtttg
     9361 ctcatcacac ccatttcctg caagagccac ggtgaccgag cagccttgag ttgaggcagc
     9421 ttgtgggtag acgcggcggg catctcggag gggcacgctc cctgccaccc tcagcctcca
     9481 ctcactggtc aggggctttg cgccccaggg caccccagga accgagcctc ctttggggtc
     9541 atgggtgcct ctcctgggag ggcgtggatt ttccaaagca gtttagagaa atgagaccca
     9601 caggcgttat ttcccatggt gaggttcttt tcagtaaccc ccaccgtata gccaggatca
     9661 gcaaagagag gcggctcctc ccggtgagac agggaccagc acctcccgga caggcttggg
     9721 tctccctcca gttcccccac ctagtctcga ggtctcacgc tgccctctcc tgtccagggg
     9781 ctcccacctg aaggagaata agtacctgat tgtggtgacc gacgggcacc ccctggaggg
     9841 ctacaaggaa ccctgtgggg ggctggagga tgctgtgaac gaggccaagc acctgggcgt
     9901 caaagtcttc tcggtggcca tcacacccga ccacctggta ggcaccggcc ccccccggca
     9961 gatgccccca accacaggga gtggcggctg caaggccccc ggcagctggg accgtctttt
    10021 ggtcctcggg agggtgtggg ttctccagcc ggccaccctt gcccctgaga ggccagcccc
    10081 tcctgctgag gagcctggag cgccccagcc cagcctcccc tctggccctg tgggaagcgg
    10141 ccccggccgt caggggtccc agccctgctc agcccaccct gaacactgcc cccaggagcc
    10201 gcgtctgagc atcatcgcca cggaccacac gtaccggcgc aacttcacgg cggctgactg
    10261 gggccagagc cgcgacgcag aggaggccat cagccagacc atcgacacca tcgtggacat
    10321 gatcgtgagg cccctgccca ggagacgggg aggcccgcgg cggccgcagg tggaaagtaa
    10381 ttctgcgttt ccatttctct ttccagaaaa ataacgtgga gcaagtggta agagccctcc
    10441 ccaccacccc cagccgtgag tctgcacacg tccacccaca cgtccacctg tgtgttcagg
    10501 acgcatgtcc ctatgcatat ccgcccatgt gcccgggaca catgtcccct gcgtgtctgc
    10561 ccgtgtgccc gggatgtgtg tccccctgcg tgtccacctg tgtgtctgcc catgtgcctg
    10621 ggacatgtgt ccgcctgtgc gtccatccgt gtgtccgtct gcccatgtgc ctgggtcgca
    10681 tgtcaccctg tgtcccagcc gtatgtccgt ggctttccca ctgactcgtc tccatgcttt
    10741 ccccccacag tgctgctcct tcgaatgcca ggtgagtgtg ccccccgacc cctgaccccg
    10801 cgccctgcac cctgggaacc tgagtctggg gtcctggctg accgtcccct ctgccttgca
    10861 gcctgcaaga ggacctccgg ggctccgggg cgaccccggc tttgaggtga gtggtgactc
    10921 ctgctcctcc catgtgttgt ggggcctggg agtgggggtg gcaggaccaa agcctcctgg
    10981 gcacccaagt ccaccatgag gatccagagg ggacggcggg ggtccagatg gaggggacgg
    11041 cgggggtcca gatggagggg acggcgggag tccagatgga ggggatggcg gggtccagat
    11101 ggaggggacg gcggggtcca gatggagggg acggcggggt ccagatggag gggatggcgg
    11161 ggtccagatg gaggggacgg cggggtccag atggagggga cggcggggtc cagatggagg
    11221 ggacgtcggg gctccagatg gaggggacgg cgggagtcca gatggagggg acggcggggt
    11281 ccagatggag gggacggcgg ggtccagatg gaggggacgg cggggtccag atggagggga
    11341 cgtcggggct ccagatggag gggacggcgg gagtccagat ggaggggacg gcgtggtcca
    11401 gatggagggg acggcggggt ccagatggag gggacgtcgg ggctccagat ggaggggacg
    11461 gcgggggtcc agatggaggg gacggcgggg tccagatgga ggggacggcg gggtccagat
    11521 ggaggggacg gcggggtcca gatggagggg acggcggggt ccagatggag gggacggcgg
    11581 ggtccagatg gaggggacgg cgggagtcca gatggagggg acggcgtggt ccagatggag
    11641 gggacggcgg ggtccagatg gaggggacgt cggggctcca gatggagggg acggcggggt
    11701 ccagatggag gggatgtcgg ggtccagatg gaagggacgg cggggtccag caggcaggct
    11761 ccggccgtgc agggtgtgga ctgtcccggg ggcgctgggg gcttctgagg gtgtctctgt
    11821 ccgccctgcc ctcagccgca ctctgttcag aaggaccttt ctggaggtag gagggtgaga
    11881 atgtgggtcc cctgcttctg tgtggctcac ataggatgac cttaaacgtt agaattagct
    11941 gctgataatt aaaacttgcc atgaggctgc tcatggacct cagatttctg gcttctccta
    12001 aaaaccatca aacccagcag ctgtgggccc gagtcccatg gccatttcct gggggtcgag
    12061 ctgtgaccct ggggggcttc tgtgctgcac gtccctccca cctgtgcctg ggggtcagca
    12121 aagccgagca gacaggaacg aaggcaggga gtggggggag ctggcgtgcg ggttggagct
    12181 cccagaccca ggctgaccag atgtgatggg gaaggtgctt taaagccctt gatccctgaa
    12241 ggctggatga agcgtctttt taaaaacctg tttcgtgagc cagcttttta gaaagaaacg
    12301 gggctgcccc aaccttgacc tgttttgtgt tccagggaga acgaggcaag ccggggctcc
    12361 caggagagaa gggagaagcc ggagatcctg tgagtgcctg actgtggggt gggggcccta
    12421 agaagctgga ggcggggaac gactaggcct cggaaacttc cggaagagtg gctgggttct
    12481 gagtgccaaa gtcacactgc ctgttccttg tgggtgggag cagacctgga ggggccacag
    12541 cccagccatc cttccacaca gccccccagg cagcccgtaa gcccccctgc cagggagggg
    12601 ctgggtgggg aggtggccca gggtgctcag gccggcaccg tccggggccc ctgccgtggc
    12661 tccttggccc aaatcctatc catagacttc cctcccccag ctccaccttg gagggcctcg
    12721 gcaccatggg ccccgtgcag cagggcccct ctctcggcct gaccaggcct gggctggagg
    12781 gaggggtgtg gggctgggtg ggactggccc ctgcccctgc tcctccgggg gtgtctcacc
    12841 atctcctcct gtgttccagg gaagacccgg ggacctcgga cctgttgggt accagggaat
    12901 gaaggtacgt gccccccctt tcctggcccg agcccggtgg tgccctcagc cttgcacagc
    12961 actaacaagc cttcctcttc ctcttcttcc gctgggtgtg tagggagaaa aagggagccg
    13021 tggggagaag gtgagtgagg ctcgacctcg gagctggtct ctccaggcgc agatgtgcca
    13081 tcctggacga gggtgtcccc ggggatgagg acagtgtccc tgacaggaga ccacgtgtcc
    13141 tgcagacccg ctccaccgcc cctcgccgtc ccctccatct ggaaggacaa ggacagccac
    13201 ccaggcaccc agcaaaggcg cctgtgtcac tttcacccca ccccagagca ggggtccccc
    13261 gggcggttac cctctgcgga gccgggggtc ccccgggcgg ttaccctctg cggagccggg
    13321 ggtcccccgg gcggttaccc tctgcagagc ggcccctccc catcactgtc agtccccatg
    13381 attctcagca gtgatgttgt cccctcgggt tgggggcacc caagcccctg cctcgcgtgg
    13441 gcctaagcca ggcttgccct gccctcccca ccccaaatac cccctcacac ccgcttcctg
    13501 tctccgcagg gctccagggg acccaagggc tacaaggtga gcgtgggctg ctgggagggg
    13561 ggagttctgc ccccacggca gcatgtctga cctgcatctg actcctgcct tcgttttccc
    13621 gcctcacagg gagagaaggg caagcgtggc atcgacgggg tggacggcgt gaaggtgact
    13681 ggggggagat aggatggacg gggagggacg aggaggaatg gggcgagatg gggagggacg
    13741 gagtggacgg cgtgaaggtg acccggggag ggatggggtg gacagtgtga aggtgaccag
    13801 gggaaggacg gggagggacg gggagggatg gggtgaggtg atcccggcag gagggacagg
    13861 gaggagtggg gtggacggtg tgaaggtgac cccagggggg tgtctgctag gcagggcttt
    13921 ccagggaggg tgtggagggc atggagggca ccaagtctga cagttgattg gcctcagttt
    13981 acccacttgg ccgtcagatt ttctagtttt cttcctcttt ccagggggag atggggtacc
    14041 caggcctgcc aggctgcaag ggctcgcccg ggtttgacgt aagtcacttc ctctcactga
    14101 tactttaaaa ctagcgctgt cagcagcacc tcgtgtggac cgttttgact tctgtctggg
    14161 cggtctgggg ctgctgccag aggccgcggt ggcctctgcc ggtggtgtca tgctgccctc
    14221 ttttctccag ggcattcaag gaccccctgg ccccaaggga gaccccggtg cctttggact
    14281 gaaaggagaa aaggtgagtg acttgcggcc cctggaggac cagggccttc acggttggcc
    14341 aagcgctgaa ttggaaacct ctcctggaag caagtcctgg tccgagcatg tcggccaccc
    14401 gtgcggcctc agaggggagg agctggtgga ggctggaggc aggcagagga gcagcgggga
    14461 cagtgcccac cgtggggaca gtggccgtgg cgctcccgcc cagagccttc cctgcagccc
    14521 gagggccttc aggcctccgc cattctgtcc cccgcacctg ccgctcgctc ggcacagatg
    14581 ggaccccacc gcgtcactcc tagcctgcga gccgcagccc agaatggctc tcagaactga
    14641 gaatgggctg ggtggcactg agggtggcga gtgggcggga gggtggtgag cgggggcggg
    14701 aggagggtgg tgagcgggtg ggagggcgag tgggcagcgg gagggcggga gcacgaggcg
    14761 ggagaaggag ctttttcgtc tgacagctga gtctgccgtt gctggtgttt tctctggagt
    14821 ttctttgttg aagctgaagt gttggggaag acaaaggcga atgctgaccc caccccaaac
    14881 attcccagac gagctcctag aacccagcag acggtttcca aatctcatct tcaagttccc
    14941 agattaccct ccaggcccta gatttgagtt tgccaatttg ccagcctggc aaagctgtgc
    15001 cttctctaat gggaaccaaa tcctgcccct tagacaagat ggcccttggc tgggcctcac
    15061 agggaacaag gttggagcat tccaggaggt ctttgtgcag ggttgtggat ggctgagggt
    15121 gctggggggt ctgggctcag acagtgttgg tcagagggag tggcctgaag tatgggtgag
    15181 aggccctgga tgtggcctct gatggctgca cccctggtgc acacccctgc cagcgtgtgt
    15241 gactcccccg gtcttcccca gggcgagcct ggagctgacg gggaggcggg gagaccaggg
    15301 agctcgggac catctggaga cgaggtgagg agcttcacag cccccacaca tgccaggtat
    15361 gggcccaggg agggtcaagg agatggagcg accattcaac ccttgttccc cacagggcca
    15421 gccgggagag cctgggcccc ccggagagaa aggagaggcg ggcgacgagg tgagtgaggg
    15481 ctcctgacac cttcctgggg aagtgcatgg cctcagcttc tgatcctctt tgctcggggt
    15541 ctactccacg tccctgagac caaatgcagt gtgtccacca gactaacgcc ggcgtctgtt
    15601 tctcttcatc ccaggggaac ccaggacctg acggtgcccc cggggagcgg gtgagtgggg
    15661 caggggcagc ctgcgctgtt ggcctcacca tgtagctgtg gacgtggcct ctgcggccca
    15721 gtctggccct cccagcactg agagccatgg cctcctgccc aagacaaatg ggtttcttca
    15781 cccacacgtc caggatgcct cttcccacag tctcagagcg ggtgggacct ggggaaccag
    15841 gagattccgg cctctgcaac cgtggggcat gcggtggagg ggtggcccct cccaggggtc
    15901 ctgctggggg agtcagtcca ggccaggcct caagccccac cccagctggg tgtgagttcc
    15961 agcagctgag gcttctcccc tccatgtctc tccactcagg gtggccctgg agagagagga
    16021 ccacggggga ccccaggcac gcggggacca agaggagacc ctgtgagtca cagttcctgg
    16081 agctgggaac caccccagga aggggcaggc ggaggctggg gctgggtcag gcctccagag
    16141 ccacaggaca catcatgaag cccctgtggc ccctcaacgt ggccagccca tccccacgcc
    16201 gtcagggagg gcagcccctg aagccggcgc ccagccatgt gcctgatgct gggacctgtt
    16261 tcatgtgaag gcgttgcccg tggacccggt gcccactttc ccaccaggcg gcttccacgt
    16321 ttctgcatcc gagcttgggt tcttctttgg aataattttc cttagttaaa attcccagcg
    16381 tgaggaagtt gggtcagtac cccagacggg aagctaggcc tgcagggcgc ctgcctggga
    16441 aggcttgaca tggaaaactc accccagagc cgagatgccg gcggcctcag aggccacccc
    16501 ccaccttcag ctccgtggac cgtgggcctc gctaggccac cccacagccc agcctcaggg
    16561 tgcagaagca cagggccctt ctctgtccct gtgacttgct gggaaatctg tgctggatgt
    16621 ggggcggggc agctggcaga ctccgggcgt ctcagtccca tccggctcag ggagagccag
    16681 ggcctggcgg gcagagtgaa ggggagagaa tgccctagtg tgcccagccg agctgccagg
    16741 cctcagaggc agcgcccccg ggtgccccct tgtccgagaa tcaagacatg cgactgtcgt
    16801 gtgctgtgac agacaggcgg ggctccagca gggccagaga gctgagccgg ggccagagtc
    16861 gccgccaccg agggatttgg ctccccagtg gggggtgggg gatttctgac ctcctccctg
    16921 ggagctcccc agaagcgcac agcccccgtg gaggggtcgg ggggacgtca aagcagggat
    16981 cgtgtgactt agtgactcag actgccttct aggcccactc ctctgagatc aggatatgag
    17041 actgacagcc aggcagagcc cagaggaagg gccagccacg cagctccagc ttcccggcgg
    17101 gccacaagtc catggctaca aacacttgcc gggtccacgg agcttgctgg agaagcaggg
    17161 atgcacgcag ggacgcctct ggggccccag gaggagctgc cggcctcctg aatgaagata
    17221 gccatagcca gccacgccga tggccacgca cgtgggccga ggaaacgctt ggcgaggcca
    17281 ggaaggggct gtgcggggag ggaaggccgg aacagcccag tgaccacctg gacagcatgc
    17341 tgtggctccc agcgtgcccg ggcagccatc ctccccaagg atggcccagc tccacactca
    17401 cggctcgttt ctcttcaggg tgaagctggc ccgcagggtg atcagggaag agaaggcccc
    17461 gttggtgtcc ctggagaccc ggtaggaagc gctgtggggt tggggggcgt tggccaattt
    17521 gggttttggg ggtagaagtg ctccagcagc tcacgcactg ggggtctgtt catttccgtt
    17581 tgagggcctc tgtgtttccg tagatctcgg gggtgtccct gcgtgggagc cggctgcagg
    17641 gggtgaggcg cggcctgggc cgggctggtg tggattgttg agagcaggcc cagcgcccgg
    17701 gggcctgacg ctgagacgct cagcccaggt ggagaagcgc tgtctggggg cccatccggg
    17761 gcaagggtgc ctcacagtga ggaagaggtg ttggagcccc tgggagacac tgggagcttg
    17821 gtcagcatct gtttttctgg gtcaggagcc aggcatgact gtggctggag gtcaactggg
    17881 gagtgtgagg ctatggaggt ttccagaatc ccagggtgtc aggatgaaaa tgcactttca
    17941 tctcattcta aattcccttc tccgagcctc tggaatcgct gtgcacgccg cacggctttc
    18001 tgtctcttcc cccattctga tgactgccat gatggtggct ccagtgtggt gttgcccgca
    18061 ggctgggctg ggccgttgca tcctcccgga gctcacctgc cccacgggga caggaaggcc
    18121 tccacacggt cacgcccgga gacagcaagt ctgtgctccc gagcttgtct gcttctgtgg
    18181 acaaatcgac cttacggctc catgtgcgca gctgcccaca caccgagcac aaggccagac
    18241 cctgggcacg gcagctgtct cagacgtcca gcaagatggg gcctcagacc cagggagatg
    18301 ggagaggccg tcccagtgca agtcacattt gtatttctgt gcacgaggtg aaatcgtgct
    18361 tttgtggtgc caacgggtgt tacacagctg ttaaaaatac ctgtgtcata gatgaggacc
    18421 agggcagggc ttggcaggcg gggtctgggc cgttcgtcca cctggtcctg cgtgccgctc
    18481 acggcagggg cagaaagggc tcccgacacc ttcctgggga agtgcacggc ctcagtctct
    18541 gatcctcttt gctctttgag ctcccggggc tccagccctg aggatgatct gacctcccat
    18601 gtggtcaccc aggacagggc caggtgcagg gcacagtgcg tggaagaggc catgcagcca
    18661 gtggcagatt gtggggaggg gacggcccag ggccacgttc caggcttggg aggctgctcc
    18721 agaccttggt agctgaaagt ctcagtggga atgagcgttc agaggccagg acttgctcgg
    18781 agaattctaa ccacaccctg cctgttttat atgttcagtt ttcaaagtaa tcaatagcca
    18841 ctataagaaa aaaacaaagc cactttcaaa gggttgtggt aagaggcagt cctgtgagca
    18901 ggccggctgc agggcctcca gggctgtggg gcaggctgca caggggctgg tgggtcccat
    18961 gcctgggggt ctgggaatag tctctaggct gctgtcctgg aggaggtttc ccccaacgcc
    19021 tgagaccagg gcaccatgtg acccatgact cacagttgcc tggctgaggc aggcacttgt
    19081 tcacctggag cctccctggg gcctttcggg gcccgggggt gtggataggt ggctttggag
    19141 ccacatttgt ccatcgggac gttgggctcc cagctggcct tccgggcttt ccctgctccc
    19201 agaacctccc tgctcagccc ttgccagcct tacccctccc ctccaccctg cccagcatgg
    19261 ggctctccct gtgtggatgc cagaagcagt tgggccctca gggctggtcc caggaggtgc
    19321 ccccagtgag gtgctctgca gaaactgccc agtctggcct cctgctgtct gtggcacagt
    19381 ctgactgtgt gtggtgaggt ccaggccttc tgcctcccac ttacctggcc cagggcacag
    19441 agacctcctt tccatccttc ctcctggccc ccttttcgtg ttcccaaggc aggatctcag
    19501 ggtaccagac taacccctgt tgaaccccaa gtttggtgag cttctggacc tccttgaggc
    19561 ccgtgtgcaa agtccccagt caagtgtgca gtcctgactg ctggggcgtt gaccacgaag
    19621 ggtgcaggag cttcacagcc aggcctgggt gcttgcacag tcggggtaga gagagcaata
    19681 cactagatgc ctcctgtctg cctggtggag gccacggggt caggatggtg aatgggccaa
    19741 gtctggtagt ggggaagttg taaacatttg aaccaccgga caggcctcat cgggaagcat
    19801 cagcctaacc acaggccagg gacaggcgtc tgagcaggca caggccaggg acaggcgtcc
    19861 gaccaggctc atggctgggg ccaggtgggc caggtgggcc aggtgggccg ggcgatgtgt
    19921 acacggctcc cttcttggct cagctgggcg cgctgggaag tgcttggggt gcctgggcta
    19981 gactccgaag ggcagggact cgccgctgga gttgtccacg gagcaggccc tcaaaggtgg
    20041 gagctggggc cagctctgga aatagacccc cacagggtcc tcatgagatg tgggggaccc
    20101 aaggaagtcc agcaggcagc ctcaggtgca ggtgggggca gggtggtgtc caggctcagc
    20161 ccacagaggg tcctgcggtt gggggtgggc taaggggacc aggccaggcc caaaggggac
    20221 catgagggag ggcagtctgg ggccactctg ataggagaag gggcaggtgg tctgcggcct
    20281 ggggacctgt agcctcaccc ctccgtgggg acctgaggca ccagccgggc actcaccgaa
    20341 gtcatctggg acaggcttca cccttccgtg ggggcctgag gcaccagccg ggcgcccacc
    20401 aaagtcatct gggagaggct tcacccctcc gtgggggcct gaggcaccag ctgggcgccc
    20461 accgaagggc ttcaacactt gtgcccaggc ccttcgtgca ggcccttcgt cagacccaag
    20521 agtgggcctg gctctccccc tgcactgatg ggactggggc cagagcctgg gggccctgat
    20581 gcctcttggt ctgagaccct cagcttaggg tcagggaggg ctcaggctgg gtgaggcctg
    20641 tggtccaacg tgccatatcc atctctctac agggcgaggc tggccctatc ggacctaaag
    20701 gctaccgagg cgatgagggt cccccagggt ccgaggtgag tcccactccc cacccacacc
    20761 cgcccaccca ggggggcctg aggatccaga acccactgtc tgcccagtgc tggccccgtg
    20821 ccctctgagg actctatggc cctgggtgtc ctggctcccg atgggacctc tcccggcccc
    20881 aggagggccc tgcttccctc caaggtcacc atgctaagcc tgctcccctc acgcctcctc
    20941 ttcctcctca gggtgccaga ggagccccag gacctgccgg accccctgga gacccggggc
    21001 tgatgggtga aagggtgagt gtccaacagc tcgggcccta gggcggaggc ctggccgcca
    21061 gaggccctgg gaagccccag ccccgcactg tggagctgcc tggggtccct gaccgggccg
    21121 ggagtgcccg cagcatcact ggctcctggc cacagtcggc acctgagcca gaggccgcct
    21181 cggcagggcc cctcctgccc cgagatccgg gtcccagggt ccacggggac cagcagggtg
    21241 gccccagggg agggagccgg cttctgggct gacggagggg ccctgcgggt gaggtgctcc
    21301 cgggcctgtg ccagccagtg ggtatcccag gccaggccga ttcgcacggt gacggctact
    21361 ctgctccccc agggagaaga cggccccgct ggaaatggca ccgagggctt ccccggcttc
    21421 cccgtaagtg tccggaggct gagcccacag gaacatgccc aagctgcctg cggcgccctc
    21481 tttagtggac tgggcactct tgggtgggcg ggctggcccc aggaccgccg gctggcccag
    21541 gaattccatg gccgggattc tgtcagctca ggcccttccg ctgtgcgccc ctcacagcct
    21601 cccctctcaa atcagaaccc ggtatcactg ccctgctttt ccatgacagg ggtatccggg
    21661 caacaggggc gctcccggga taaacgtgag tacgccccct cctccatctg gctgtgggca
    21721 cacaaacatt cacagtcaca gggacacgca cgtgtgaaca cacatgtgca cacaggctcc
    21781 cgagcaaaca cacggggtac acaggcaccc acggctgccc cactgtctgt ggccacagcc
    21841 ccagttggca tcggctcctg caggccctgc gaggctccca ctgtggtgtg gcctgtgggt
    21901 ctcctcacgg ccctgactgc ccggtgaccg atctcccctc ggtgcgcagg gcaggcccag
    21961 ccccagaggc cgccccacgg ctctctaggc cactccggga cccagtttct ccagcccagg
    22021 aaatgtgtgt ggtgggggaa gggaagagaa gagtgcctct cttatcttta tttttttcct
    22081 tttaaaattt ccacttccta aaaacaaaat aaaacccttg ttaaccaagt gctctcccgt
    22141 cactgcaggg cacgaagggc taccccggcc tcaaggggga cgagggagaa gccggggacc
    22201 ccggagacga tgtaagtgtg gatgggaggc agggccagcc ccaagtccac ctgagccaga
    22261 gggctgggcc cttgaagggc agtggaccag gacccgcttg gggaggcctc atgggccccg
    22321 gctgctggat gctctgtgga cggggccagc gcgcagatgc ccgggtggtg cacggtctgt
    22381 tgacacaacg ctgttccctt ctagaacaac gacattgcac cccgaggagt caaaggagca
    22441 aaggggtacc ggggtcccga gggcccccag gtgggtggat gtggctgggt gaggccacgg
    22501 tgggctgtgc ctgggacgcc ggatgctggg gctggggaat gctggaagag gctgggagag
    22561 tgggaggcgg cgggagggaa ttttggggag cacgtcatct gggaggccct gggggtggga
    22621 ggtgccggtc accagggcca ggtggtggcc agggcagcag agccgagccc agggacacag
    22681 cgggtcctca gggtggggcc cacctgggat ggccgcctgg accaccagtg tgcgaagccc
    22741 cagctgccct cacagcaccg tcactggagg acgaggggct gggtagggag ggaccgggca
    22801 ggggtgggct tgatgagggg cagggccctg ggggtggggg ctgtctcagc tcaggaagca
    22861 cagtgggctc ctcaccctca gagctcctct actccgtttc tcggacaggg acccccagga
    22921 caccaaggac cgcctgggcc ggacgtaagt ggggctctgt gaacattgct gggggcgacc
    22981 actgtagctt ccatcccttg gggtgtgggt cctgtccatg ggtgctcctg tagacgctgc
    23041 tcacgggggg gtgggttgtg gacaaagagc tggtgccagg ccctagggac ccgtgacggc
    23101 catgggagga cccgtgagga tcataggggg atgtgtgagg accatagagg ggacatgtga
    23161 ggatcatggg ggacatgtga ggatcatggg ggggacgtgt gaggatcatg ggaggacgtg
    23221 aggatcatgg agggggacat gtgaggatca tgggggaccc gtgaggatca tgggggaccc
    23281 gtgtgaggat catggggggg gacgtgtgag gatcatgggg ggacctgtac ccatgaggac
    23341 catgagggga cccgtgacgg ccacggggag acccatgact gcgctgtttc tatgaccacg
    23401 tcaggggtcc agcccagtag caggggtgta gtgggcagag ccgggcacac ctgcaaagaa
    23461 cctcctgccc aaaccccgcc ctgtgggggc cccagggagg gtgacctgga gatccagcag
    23521 cccacagtcc ccgctgggag gggctgtcta tggccccagt accctcgtct ctccctcccc
    23581 aggaatgcga gattttggac atcatcatga aaatgtgctg tgagtatctc tgagaagccg
    23641 tcctcgttag ggagagcagg gccgccagcc tggcctgttc cactcctaga agggtgtctc
    23701 cactgttggg ggcctgggtc tctgggtaca tccttgagga ggctcctcag ccagccccta
    23761 ccggcctcca aagccctccc aggcccccgg gtccccgcac aggctgagag tccccggtgc
    23821 ggtgcagagc tgccacgtgg ggagggcggc cggggaggcg gggaggcggg gcaggaggcc
    23881 ggggaagggg ggaggccggg gaaggagggc ggccggggag gcggggaggc tgccccaaga
    23941 gtaaaagcct ttctgacgtg cgcaggacgc ggccctgact ggtctaactg actctttctc
    24001 ttctcctcag cttgctgtgg tgagacccag gctctagctc ctgagagaat ggatcccggg
    24061 ggtcggggag cgaggcctgg gtcccacaca tgtcacagga cagcacatgg cactctggtc
    24121 cccgcccgca gctccctgca cctgcccgcc ccctctgggg cctgctccaa gccagcaggg
    24181 ttcccgggtg ttgggctggg ccccgccctc tttcacccat aactgaaata accaggagca
    24241 ggcttggggg ggtccctgct ccatcattct ggcccacagg ccccacccta gcctggctga
    24301 gcaacgccag ccctgaccag ccgccggaca gagcagcctt tacggggcca tgggaggggg
    24361 tgggcttttc tggggctgag acggggggac cccaacgtgt caggtgagga tgtggcagcc
    24421 aaggaggggc cagggcggtg gaggggaggg gccagggcac tggaggggag gggcgtgctc
    24481 tgctgacacc gcccccgcct gcagaatgca agtgcggccc catcgacctc ctgttcgtgc
    24541 tggacagctc agagagcatt ggcctgcaga acttcgagat tgccaaggac ttcgtcgtca
    24601 aggtcatcga ccggctgagc cgggacgagc tggtcaaggt gaggcctcgc cccgcccggc
    24661 tttctcaagc ccaggtgcac cccgaccctg ccggccgccc ctgcccgcgc cagacctcag
    24721 cctcccgagg ccaccgctgc atccctgtga cttccctact catgacaagg atgccaggca
    24781 cgcgccagcc cgtccaggcc tccagctcca cctggcgagg ctggcccatt gtacacaggc
    24841 gccccagatg agggagggtc tccccctctc cttgaagggc ggtagtctgg ggtcctgagt
    24901 gctgggtgtg ggcttgtccc tcgtggacag aacccaggag ggcttcatcc accaaggaag
    24961 attgctttgc agggtaccca ggtcccgggg gctgtgccac cctctgggca cccggagcca
    25021 atcgcagggt acccaggtcc cgggggctgt gccaccctct gtgcacccag agccaatcgc
    25081 aggggaccca ggtcctgagg tcctgggggc catgccaccc tctgggcacc cgcagccaat
    25141 agagtcaccc ttgggaagct tatgcggacc tggggcagca ctcgcgtcct gaccccggtg
    25201 ccggtcccac agttcgagcc agggcagtcg tacgcgggtg tggtgcagta cagccacagc
    25261 cagatgcagg agcacgtgag cctgcgcagc cccagcatcc ggaacgtgca ggagctcaag
    25321 gagtgagtgc cccacgcggc caggaccctc ccacccctcg ccccgaccgc tgttcccacg
    25381 gcaggtcggc cctgacccct gatcccaggt gggctcggcc ccgcggcagg cctggcccca
    25441 accggccctt cctgcccttt gctatgcaga gccatcaaga gcctgcagtg gatggcgggc
    25501 ggcaccttca cgggggaggc cctgcagtac acgcgggacc agctgctgcc gcccagcccg
    25561 aacaaccgca tcgccctggt catcactgac gggcgctcag acactcagag ggacaccaca
    25621 ccgctcaacg tgctctgcag ccccggcatc caggtggggt ggccaccccc aggctgcacc
    25681 tgccccgcct agggcgcccc gccagccagg gtggccttgt ccccagaaag acgagggcag
    25741 agcaggctgc gccacaccga tactgtctgt ccccacaggt ggtctccgtg ggcatcaaag
    25801 acgtgtttga cttcatccca ggctcagacc agctcaatgt catttcttgc caaggcctgg
    25861 caccatccca gggccggccc ggcctctcgc tggtcaagga gaactatgca gagctgctgg
    25921 aggatgcctt cctgaagaat gtcaccgccc agatctgcat aggtgcgcat ggggccaccc
    25981 gggcagtccc agatctgcgt aggtgcgcgc ggggccgccc gggcagtccc agatctgcgt
    26041 aggtgcacgc ggggccgccc gggcagtccc agatctgcgt aggtgcacgc ggggccgccc
    26101 agggccgtcc cagatctgtg taggtgcgcg caggcgccca gggctgtccc agaggcctcc
    26161 tcccagctca ctgttacctc caggggcacg gccaccctgt aggtgcgcac ggggccgcct
    26221 ggggctgtcc cacaggcatc ctcctcccgg ctcgctgtga cttccggggg cacggccacc
    26281 cctgtgctcg gccgggaggt cctgtgacat ctccttgcgg ggttataggt ggagcagtgg
    26341 gctcacactg cacggctttt ctcttttaca gacaagaagt gtccagatta cacctgcccc
    26401 agtgagtacc tcggcggccg ggacacgtgg ggaggagggc accgtggttg gggcgagggc
    26461 tctgagagga cggggctctg ggaggagggc ctggcggtca cgagagtagg tgcatggctc
    26521 actccggtgg ctgagcacca ccgtgccgtg ccctctctgg ggagcttaga cgctctctgg
    26581 ccggcccact gcggctgcat caccagggcc tcatgctaac ggctgcccac cccgccccgc
    26641 agtcacgttc tcctccccgg ctgacatcac catcctgctg gacggctccg ccagcgtggg
    26701 cagccacaac tttgacacca ccaagcgctt cgccaagcgc ctggccgagc gcttcctcac
    26761 agcgggcagg acggaccccg cccacgacgt gcgggtggcg gtggtgcagt acagcggcac
    26821 gggccagcag cgcccagagc gggcgtcgct gcagttcctg cagaactaca cggccctggc
    26881 cagtgccgtc gatgccatgg actttatcaa cgacgccacc gacgtcaacg atgccctggg
    26941 ctatgtgacc cgcttctacc gcgaggcctc gtccggcgct gccaagaaga ggctgctgct
    27001 cttctcagat ggcaactcgc agggcgccac gcccgctgcc atcgagaagg ccgtgcagga
    27061 agcccagcgg gcaggcatcg agatcttcgt ggtggtcgtg ggccgccagg tgaatgagcc
    27121 ccacatccgc gtcctggtca ccggcaagac ggccgagtac gacgtggcct acggcgagag
    27181 ccacctgttc cgtgtcccca gctaccaggc cctgctccgc ggtgtcttcc accagacagt
    27241 ctccaggaag gtggcgctgg gctagcccac cctgcacgcc ggcaccaaac cctgtcctcc
    27301 cacccctccc cactcatcac taaacagagt aaaatgtgat gcgaattttc ccgaccaacc
    27361 tgattcgcta gatttttttt aaggaaaagc ttggaaagcc aggacacaac gctgctgcct
    27421 gctttgtgca gggtcctccg gggctcagcc ctgagttggc atcacctgcg cagggccctc
    27481 tggggctcag ccctgagcta gtgtcacctg cacagggccc tctgaggctc agccctgagc
    27541 tggcgtcacc tgtgcagggc cctctggggc tcagccctga gctggcctca cctgggttcc
    27601 ccaccccggg ctctcctgcc ctgccctcct gcccgccctc cctcctgcct gcgcagctcc
    27661 ttccctaggc acctctgtgc tgcatcccac cagcctgagc aagacgccct ctcggggcct
    27721 gtgccgcact agcctccctc tcctctgtcc ccatagctgg tttttcccac caatcctcac
    27781 ctaacagtta ctttacaatt aaactcaaag caagctcttc tcctcagctt ggggcagcca
    27841 ttggcctctg tctcgttttg ggaaaccaag gtcaggaggc cgttgcagac ataaatctcg
    27901 gcgactcggc cccgtctcct gagggtcctg ctggtgaccg gcctggacct tggccctaca
    27961 gccctggagg ccgctgctga ccagcactga ccccgacctc agagagtact cgcaggggcg
    28021 ctggctgcac tcaagaccct cgagattaac ggtgctaacc ccgtctgctc ctccctcccg
    28081 cagagactgg ggcctggact ggacatgaga gccccttggt gccacagagg gctgtgtctt
    28141 actagaaaca acgcaaacct ctccttcctc agaatagtga tgtgttcgac gttttatcaa
    28201 aggccccctt tctatgttca tgttagtttt gctccttctg tgtttttttc tgaaccatat
    28261 ccatgttgct gacttttcca aataaaggtt ttcactcctc tccctgtggt tatcttcccc
    28321 acaaagtaaa atcctgccgt gtgccccaaa ggagcagtca caggaggttg gggggcgtgt
    28381 gcgtgcgtgc tcactcccaa cccccatcac caccagtccc aggccagaac cagggctgcc
    28441 cttggctaca gctgtccatc catgcccctt atctgcgtct gcgtcggtga catggagacc
    28501 atgctgcacc tgtggacaga gaggagctga gaaggcaaca ccctgggctt tggggtcggg
    28561 agcagatcag gcctcagtgg gctggggccg gccacatcca ccgaggtcaa ccacagaggc
    28621 cggccacagg ttctaggctt ggtactgaaa tacccctggg agctcggaag gggagttgag
    28681 atactgcagg gcccatagga agaagtcttg ggaggctcca cctttggggc agaggaagaa
    28741 gtcttgggag gctccacctt tggggcagag caagaagagg gcggagggca gaggcagcga
    28801 gggctcatcc tcaaaagaaa gaagttagtg gcccctgaat cccagaatcc ggggtgcacg
    28861 gctgttctgg gggccgctag gggactaaga ggatcggccg agggctgggc tggaggaggg
    28921 cagcagggat gggcggcgag ggtgagggtg gggcttcctg aaggccttca cctgcgggga
    28981 ccccggcgag cccctcaggt gccacaggca gggacacgcc tcgctcgatg cgtcacacca
    29041 tgtggccacc agagctgcgg gaaaatgctg gggaccctgc atttccgttt caggtggcga
    29101 acaagcgccc ctcacagaac tgcaggtaga gacgggcccg gggcagacgc agtgaggcgg
    29161 tgggcggggc ccggggcaga tgcagtgagg cggtgggcgg ggcccggggc agaggcagcg
    29221 agcggtgggc ggggcccggg gcagacgcag tgaggcggtg ggcggggccc ggggcagagg
    29281 cagcgggtgg tggccggggc ccggggcaga cgcagtgagg cggtgggcgg ggcccggggt
    29341 agtcgcagta ggtggtgggc ggggcccggg gcagacgcag tgaggtggtg ggcggggccc
    29401 ggggcagacg cagtgaggcg gtgggagggg cccggggcag acgcagtgag gcggtgggcg
    29461 gggcccgggt cagaggcaac gggtggtggg cggggcccgg ggcagacgca gtgaggcggt
    29521 gggcggggcc cggggcagat gcagtgaggc ggtgggcggg gcccggggca gatgcagtga
    29581 ggcggtggga ggggcccggg gcagacgcag tgaggcggtg ggcggggccc ggggcagacg
    29641 cagtgaggcg gtgggcgggg cccggggcag acgcagtgag gcagttgcca gcctctctca
    29701 gctgcctcat gggattcgca ctgcagctgc ggccctggcg cgacaagggc tggacttggc
    29761 cagcgggacg gtccctcacg gcgctgaggc ccacactctg cgtggagcct ccccgtgccc
    29821 aggctaccct gcaaggtcct cggagaggct tcctccagcc ccagccccca cacagctccg
    29881 gcccaggccc gctcttcccc atcccagttg ctttgcgctg tatacggcca ggtgaccccg
    29941 agccggccct gagccctcgt cccggcttcc tcccctgtaa gctgggtgaa ggactccatg
    30001 gcacccacct gagagggttg tggcgaggcc caggcccctc gtgcccacac ggccggcggc
    30061 ccatgcctgg caggggctgg gaggaggctg gggcgaccag aggggagcgg cctgtcctgg
    30121 aggaggccca gggaccctgg tgagagggtc tctcccaagt gctctctatg ggaccccctt
    30181 cctctgcgcc cgtccttcac ggacctctcc gggtcacccc tgggctgcac actgggttca
    30241 ggggggcctt gaggtggggc ccctgttccc aagtcccggc ggggtttctc ctgaacctca
    30301 a
//

