LOCUS       NG_008028              16284 bp    DNA     linear   PRI 05-NOV-2010
DEFINITION  Homo sapiens cholinergic receptor, nicotinic, delta (CHRND),
            RefSeqGene on chromosome 2.
ACCESSION   NG_008028
VERSION     NG_008028.1  GI:190358475
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC092165.4.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The acetylcholine receptor of muscle has 5 subunits of 4
            different types: 2 alpha and 1 each of beta, gamma and delta
            subunits.  After acetylcholine binding, the receptor undergoes an
            extensive conformation change that affects all subunits and leads
            to opening of an ion-conducting channel across the plasma membrane.
            [provided by RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16284             AC092165.4         50279-66562
FEATURES             Location/Qualifiers
     source          1..16284
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33-q34"
     gene            <1..4505
                     /gene="LOC646960"
                     /note="trypsin serine protease-like"
                     /db_xref="GeneID:646960"
     mRNA            join(<110..217,605..655,760..949,1304..1403,1491..1650,
                     1849..1991,2205..2367,2561..2734,2828..2992,3096..3158,
                     3527..3633,4005..4505)
                     /gene="LOC646960"
                     /product="trypsin serine protease-like"
                     /transcript_id="NM_001195129.1"
                     /db_xref="GI:304376265"
                     /db_xref="GeneID:646960"
     CDS             join(<110..217,605..655,760..949,1304..1403,1491..1650,
                     1849..1991,2205..2367,2561..2734,2828..2992,3096..3158,
                     3527..3633,4005..4295)
                     /gene="LOC646960"
                     /exception="unclassified translation discrepancy"
                     /codon_start=3
                     /product="trypsin serine protease-like"
                     /protein_id="NP_001182058.1"
                     /db_xref="GI:304376266"
                     /db_xref="GeneID:646960"
     gene            5001..14284
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /note="cholinergic receptor, nicotinic, delta"
                     /db_xref="GeneID:1144"
                     /db_xref="HGNC:1965"
                     /db_xref="MIM:100720"
     mRNA            join(5001..5056,5318..5463,6190..6234,7051..7160,
                     7290..7445,7651..7760,8728..8928,10141..10252,
                     10331..10445,12720..12924,13013..13131,13919..14284)
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /product="cholinergic receptor, nicotinic, delta"
                     /transcript_id="NM_000751.1"
                     /db_xref="GI:4557460"
                     /db_xref="GeneID:1144"
                     /db_xref="HGNC:1965"
                     /db_xref="MIM:100720"
     exon            5001..5056
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             join(5005..5056,5318..5463,6190..6234,7051..7160,
                     7290..7445,7651..7760,8728..8928,10141..10252,
                     10331..10445,12720..12924,13013..13131,13919..14101)
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /note="cholinergic receptor, nicotinic, delta polypeptide;
                     acetylcholine receptor subunit delta"
                     /codon_start=1
                     /product="acetylcholine receptor subunit delta precursor"
                     /protein_id="NP_000742.1"
                     /db_xref="GI:4557461"
                     /db_xref="CCDS:CCDS2494.1"
                     /db_xref="GeneID:1144"
                     /db_xref="HGNC:1965"
                     /db_xref="MIM:100720"
     exon            5318..5463
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     STS             5961..6221
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /standard_name="GDB:439020"
                     /db_xref="UniSTS:157287"
     exon            6190..6234
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            7051..7160
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            7290..7445
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            7651..7760
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     exon            8728..8928
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=7
     exon            10141..10252
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=8
     exon            10331..10445
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=9
     exon            12720..12924
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=10
     exon            13013..13131
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=11
     exon            13919..14284
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /inference="alignment:Splign:1.39.8"
                     /number=12
     STS             14116..14274
                     /gene="CHRND"
                     /gene_synonym="ACHRD; CMS2A; FCCMS; SCCMS"
                     /standard_name="D2S2727"
                     /db_xref="UniSTS:51961"
ORIGIN      
        1 tgtcccaggc tggtgggtct cccgaggcag ggctcagggc tggggccagg aggatgaggc
       61 tgaggctctt ccccaaccac gcatgattgt gtgccccctg tcccagcagt tctgtcggcc
      121 caggggactc aggcgttgca ggcagcccag aggagcgccc agtgggcaat aaaccgagtg
      181 gcgatggaga tccagcacag atcgcacgag tgccgaggtg cccaccctgc cccccgtgcc
      241 ccagtgagct tgctgcctac cctgggccca ttctgctgcc tctgtccctt cccttcagtc
      301 ttcactctcc tcttgggggc agagactgtg ttgggccgca acctagacta cgtttgtgaa
      361 ggtctgtctc tccgagtgga aaggacacgc taggcttggg gcatggcctg tgcaaaggca
      421 gggaggcgga aacactctgg gctcctgtgg tgaccaggag aagttcatgg ttgctgaaat
      481 agaacccgtg tgggctggag ggctgagcgc gaaaggagag atggggagag agaggctcgg
      541 cccagcctgg ggtgaggaca ggcgagaggg cagcagtgag actcaaaggt ctgtttctct
      601 gcaggatctg ggcgccccag gcctcaagct ctcctccagg acccacctga gccaggtgag
      661 gttgaaaagg ctcgaggggg caggcctgag agccgggtgg gcctcgaagg cgaggatggc
      721 cagaacatgt ccctcgtgac accccttgcc cctttctagg gccgtgcggc gagaggcgtc
      781 cgagcactgc caatgtgacg cgggcccacg gccgcatcgt ggggggcagc gcggcgccgc
      841 ccggggcctg gccctggctg gtgaggctgc agctcggcgg gcagcctctg tgcggcggcg
      901 tcctggtagc ggcctcctgg gtgctcacgg cagcgcactg ctttgtaggg taagtaggac
      961 ccccaggcct tgcccagctg gggtccccgg cgctgggccc cgcacctgcc gggttgtccg
     1021 gcgggcgacg cgcgggaaag gtggtctctg ctgccccctg gcggcggccg gccccgggct
     1081 tccccatctc aaggcgccgc gcccgccccg ccaggatgcc agcccggagg gggtggcacg
     1141 gccgggcgag ttcgccccct ctgggacggg acccctcccc ggcccgccct ccgtgccccc
     1201 aggtggagaa agcccggcat gcgggcggag gggcagggtc tccgaggggc ctgcggggtg
     1261 tgcccctgtc cttcctgcgt ctcagctgcc gctcgacccg cagcgccccg aatgagcttc
     1321 tgtggactgt gacgctggca gaggggtccc ggggggagca agcggaggag gtgccagtga
     1381 accgcatcct gccccacccc aaggtgagaa ggcagtcccc aggcccccaa ggctgggcac
     1441 cgcaccccca cccgtgcttc cttgaccctg cgccgcctcc ccctcctcag tttgacccgc
     1501 ggaccttcca caacgacctg gccctggtgc agctgtggac gccggtgagc ccggggggat
     1561 cggcgcgccc cgtgtgcctg ccccaggagc cccaggagcc ccctgccgga accgcctgcg
     1621 ccatcgcggg ctggggcgcc ctcttcgaag gtactgggcg tgggtgagcc ggcgcgtggt
     1681 gggaagaact gggggtccga ggtaatagag tgtagggagg ccgggttgcc ttggaaaaat
     1741 gctgcctgct ctttcaaagg gggaggaatc aaggggggtg gtgggaaggg gaccctcaag
     1801 gcggggctct tgccctccaa acctgagcct tccacccctt ccctgcagac gggcctgagg
     1861 ctgaagcagt gagagaggcc cgtgttcccc tgctcagcac cgacacctgc cgaagagccc
     1921 tggggcccgg gctgcgcccc agcaccatgc tctgcgccgg gtacctggcg gggggcgttg
     1981 actcgtgcca ggtatgaacc cagtctgatg agaaaaggcc ggctgagcct tcccagggcc
     2041 actacggcct cttttccttc cacgtctgtc tgtcactcga cttctctgag cctctctgtc
     2101 ctcatcccta aaatggacac aagtggcaag ctcacacctg ccaggcgtaa ggcaggcgtc
     2161 atagggggca ggtgaatgca gcgtcctctc tcttggcccc gcagggtgac tcgggaggcc
     2221 ccctgacctg ttctgagcct ggcccccgcc ctagagaggt cctgttcgga gtcacctcct
     2281 ggggggacgg ctgcggggag ccagggaagc ccggggtcta cacccgcgtg gcagtgttca
     2341 aggactggct ccaggagcag atgagcggtg agcgccctct ttccaatgcc ccgtccccag
     2401 tgccccaacg gacaaccgtg ggacaagccc gtttccaccc ggcccatgcc cattcccagc
     2461 tcccttctgc ctcgggaaag cctgtctcct tccggggaag gagtgagggg gctagggccc
     2521 caaacagagg gtgagctgac ccctgtcccg cccgcagcag cctcctccag ccgcgagccc
     2581 agctgcaggg agcttctggc ctgggacccc ccccaggagc tgcaggcaga cgccgcccgg
     2641 ctctgcgcct tctatgcccg cctgtgcccg gggtcccagg gcgcctgtgc gcgcctggcg
     2701 caccagcagt gcctgcagcg ccggcggcga tgcggtcagt tctgttcacc cggacccgga
     2761 cggggggcag aggggagggg gcctggccag cctctgaccg ccgctccgac tcctgtccgg
     2821 tccgcagagc tgcgctcgct ggcgcacacg ctgctgggcc tgctgcggaa cgcgcaggag
     2881 ctgctcgggc ctcgtccggg actgcggcgc ctggcccccg ccctggctct ccccgctcca
     2941 gcgctcaggg agtctcctct gcaccccgcc cgggagctgc ggcttcactc aggtaccccg
     3001 cgccctccag cccagcccag ccctggcccg gccccacccg cgcggcacag ccactttctc
     3061 cgccgaggcg gtaccctaac cctgtgcctc cccaggatcg cgggctgcag gcactcggtt
     3121 cccgaagcgg aggccggagc cgcgcggaga agccaacggt aatgacgccc cctgccgacc
     3181 ttcaggaggg gataggctga gggcctggac gaggtcggaa gcgcttctac tgcagctccg
     3241 gaaagggctt accccatggg gcaacagggt ggactcgttc tcccctcccc gccatagagc
     3301 gtatgactct tttggagtac ttgtggtttt agctctcatc agtgtcaaac agagatgctt
     3361 tgcctggtgt tactgcttaa cttctccgag cctcagtttc cccacctata gcataagagg
     3421 ataagtgtgt cccctgggag gccatcctga ggtgctggtg ggagtgccac ccccagttcc
     3481 ataccgcaac cgttcattat tcccggggcc tctcctcttc ctccaggctg ccctgggctg
     3541 gagcccctgc gacagaagtt ggctgccctg cagggggccc atgcctggat cctgcaggtc
     3601 ccctcggagc acctggccat gaactttcat gaggtaggtc cccaggcttc cagactcctt
     3661 cacgatggcc tgggaaggct gagacccagc ccagggaaga tgcagagggc ccagcccaga
     3721 taccctccca gcagcctggg gtcgcctctg ccccagctct gggggtaggt agagggtccg
     3781 aggggaaggg agtggggcct gcggagtgtg agccaggcca ctgggggtgg tggtggggag
     3841 agtgagtaga ggggtgggtg ggagtgtcca catgagcggg aaatgagcag ggtttccagg
     3901 tctaggtgag agtttctggg gcccaggggg agagggggtg acctctgggg tttcaactca
     3961 ggagtgagtt tctgggcccc tgatccccac tcctccatct gtaggtcctg gcagatctgg
     4021 gctccaagac actgaccggg cttttcagag cctgggtgcg ggcaggcttg gggggccggc
     4081 atgtggcctt cagcggcctg gtgggcctgg agccggccac actggctcgc agcctccccc
     4141 ggctgctggt gcaggccctg caggccttcc gcgtggctgc cctggcagaa ggggagcccg
     4201 agggaccctg gatggatgta gggcaggggc ccgggctgga gaggaagggg caccacccac
     4261 tcaaccctca ggtacccccc gccaggcaac cctgagccat gtctgggccc ccagcccctg
     4321 gggaggacct actgctccca ggggctgaga ggggttcggg agcataatga caaactgtcg
     4381 ctgccccagt ggctgggtgt gtgtgggtgg gatggggtgg gggtcctggg ccccccgtgt
     4441 cttcccaggt ttacaatcag agaatcacag ctgctttaat aaatgttatt tataatacac
     4501 ggaaacaact ctggagcttt cttgggatgg gacctggtgg gtggacattc agtctcaggg
     4561 gtggggccca ggcagggctg cctctggaag cagttggcaa gggtaacaga tgctggaaag
     4621 gggctgtaag gcccctatct gagcctatct cctgcctcct gagaagcagc agcagctggc
     4681 ctgcctgttg ccccgccccc gtgcatggct gcccagcgct ggccccagtg cccagcgtct
     4741 ccgcccagca cccccccggc cctccctccc caccccccgc ctccgagctg cggggagtcc
     4801 cagcctggga tctttgcctc atgtccttgg gctcctgccc tggctggccc gtcccccacc
     4861 gccatgaggt gtcagattgt gtttccggct gcctcttccc gttgaccccc tcctccccca
     4921 acacctgtcc cctctcccgc ccaccctcat tccacagccc tgtagacagg aggggcagat
     4981 gcacgtccca gtcagaggga tgggatggag gggccagtgc tgacactggg gctgctggct
     5041 gccctggcgg tgtgtggtaa gggaagacac cctccccacc ctggggtccc ccgtgatgct
     5101 tacccaggcc ccacaccgca tggctcctca ctcactccac tcccactctg ccatctctcc
     5161 ctgtgggggg ccgccttctg gggtccccac tcccagggag tggttgggtt cccccctgct
     5221 catcccaacc tcatggtcca gcaggacctc agggcagctt ccttcctgag tcccctgccc
     5281 agggccccat tcagtccttg tcgctgaccc tccccaggca gctgggggct gaacgaggag
     5341 gagcggctga tccggcacct gtttcaagag aagggctaca acaaggagct ccggcccgtg
     5401 gcacacaaag aggagagtgt ggacgttgcc ctggccctca cactctccaa cctcatctcc
     5461 ctggtgagag gccctccggt gctgggttgg gagggagggc agggatggct ttccagtacc
     5521 aggatagcca tggaggaagc tagaagcccc cacctggcct atggccactc ccttcctggg
     5581 aaacgtgctg cggctgctct gtgccctgag aggctgctgt cctgcccctc cagtgtcagc
     5641 tctgcggtgt cccccaacca cacccatagc atgccccatc tgtgacacac ttcagaggcc
     5701 actggtcctc tctgctccct ggcggcctac ccactcctga ctgcgagtga tcagggccca
     5761 gatgccacgg tttccctggg tgccaattga cagtgggtga atgtaggctg ggtgtggtgg
     5821 ctcatgcctg taatcccagc actttgggag gcccaggtgg gtggatcacc tgaggtcagg
     5881 agctcgagac cagcctggcc aacatagtaa aacctgatct ctactaaaaa tacaaaaatt
     5941 agccgggtgt gatggtgtgg gcctataatc ccagctacta ggaaggctga ggcaggagaa
     6001 tcgcttgaac ccaggaggca gaggttgcag gttgcagtga gccaagctcg tgccactgca
     6061 ctccatcctg ggcaattgag caagaccctg gaaaaaaaaa gagagagaga gagagagaga
     6121 gagtgggtga atgtgtgcgg ataaaagaat gatatggccc tgaaggatgg ccctaccgtc
     6181 taattacaga aagaagttga ggagaccctc actaccaatg tgtggataga gcacgtaaga
     6241 atgcccctcc cagccgggcg cagtggctca tgcctgtaat cccagcactt tggaaggccg
     6301 aggggggtgg atcacgaggt caggagatca agaccatctt ggctgacacg gtgaaacccc
     6361 gtctctacta aaaatacaaa aaattagctt ggtgtggtgg tgggtacctg tagtcccagc
     6421 tactcgggaa gctgaggcag gagaatggtg tgaacgcagg aggcggagct tgcagtgagc
     6481 cgagattgcg ccactgcact ccagcctggg cgacagaaca agactccatc tcaaaaaaaa
     6541 gagaatgccc cgcccagagc cggtggggtc ggggagggaa tgcagggcac cagattgctt
     6601 ctgcatggag atcccgtctg ccttggacac tgttctccag gaggggttgg tgcctcccta
     6661 cagggaagcc ccaggcccaa ctgtccttcc cccacctagt gccctcacca gccctgatgt
     6721 caccttcaag tggattagga ttcacatgtt ggaaaattgc cactttatct tgatgtttat
     6781 tagaaaacat tctcttcctg cctgtcaaaa gtccacagta cagacacaaa tcgtctatgc
     6841 tcacagtaga aataatgctc ccttagttgt gcagtgagca tcctgcacag ctgtccatga
     6901 cagacctgaa tccgcactct gtacctgcct tccccaaacc tcttttgtca cagctctcag
     6961 accctgttca gtcttctctc agggaagtgg ggggagccag gagcctggat ggctgcagag
     7021 tgcactggtg acatgccttt gggattccag ggctggacag acaaccggct gaagtggaat
     7081 gctgaagaat ttggaaacat cagtgtcctg cgcctccccc cggacatggt gtggctccca
     7141 gagattgtgc tggagaacaa gttgagccaa gccctccctg acctcccctc tgtcaccctg
     7201 cctcctttcc ttaagcctcc tctgcctccc ccaactctgc cagtcgtgag tggccagagc
     7261 tcactatggt tcttgtccct gtcccccagc aatgacggct ccttccagat ctcctactcc
     7321 tgcaacgtgc ttgtctacca ctacggcttc gtgtactggc tgccacctgc catcttccgc
     7381 tcctcctgcc ccatctctgt cacctatttc cccttcgact ggcagaactg ctccctcaag
     7441 ttcaggtgtg cccttttctc cagccacccc tcaccccaaa gcaccctgcc agaggccaaa
     7501 gaaggtgact gaagcaccct cagacagagg cccctgccct gtctggatta gtgctgccct
     7561 ccccacaatg gtcctccctt accagccctt ccccactctg tggccccagc cactggccga
     7621 gtgtcactct ctgcccattg ccctccccag ttccctcaag tatacggcca aagagatcac
     7681 cctgagcctg aaacaggatg ccaaggagaa ccgcacctac cccgtggagt ggatcatcat
     7741 tgatcctgaa ggcttcacag gtgctgggaa cagccgccag tgggtgggca ggtccctcag
     7801 acacacacag acacactggc cctgtccacc ccagagacac acacgtgcac acacacacac
     7861 acttaggaca ccaatacaca gctcctcaca cacgcagcta gacacagaag ggcagacaca
     7921 tatccgccca cagaggagca cacagacact cacacttcct gaatgcaaag ctatcccaaa
     7981 ggcagagaga gaaggtgcca gggccctccc catgcctctg cccaggcccg gaagtcatgc
     8041 ttctcccaca tgagatgcct gtggctgaca ggggtttagt ctttcctgtg cctggtgagc
     8101 ccaggggtgt ggttggcatg agggctgtgt tatcctgatg ggggtgtctg ccacccctcc
     8161 tgacatcctc atccccgatc tgtacccagg ctcggatcct ccatggggcc taccacttgc
     8221 cctgtccatc agaagggacc ctgtctcact gtctcaggct ggcacatcat ggcagggata
     8281 gttttactgt cactggctca ttatccccaa ggcccaggcc gaggagtggc tcaattaatg
     8341 tccaggaggc ttttctttgt tactcaggaa gacaggctca atgtctgaga gcatttgttt
     8401 gacttggtgt cttaatctgc aatacctgtt tttggctcgt gtatcttttg agccaaaaga
     8461 tactccttat ttgagtcctg tatggcctca gcttctattt tttccgaaaa gataaaaaag
     8521 aaatcagtca cagaggaaga tttcccctca cagatggaaa cttccatccc gaccccccag
     8581 ggaacgacac ccaccaacgg gaccccgtag acagcccatc tgcgtctctg gactggcttg
     8641 ccctgcccag cccctcattc tgtccccagg ccctgcctag cccccttggc ctggcctgac
     8701 cctaagatgt ccatgtgccg ccctcagaga acggggagtg ggagatagtc caccggccgg
     8761 ccagggtcaa cgtggacccc agagcccctc tggacagccc cagccgccag gacatcacct
     8821 tctacctcat catccgccgc aagcccctct tctacatcat caacatcctg gtgccctgcg
     8881 tgctcatctc cttcatggtc aacctggtct tctacctacc ggctgacagt gagcctccag
     8941 gccccgtccc ctgctccccc tccccaagcc cacctgagca cagccagccc cagccctgcc
     9001 ccctcacttc ctcctgggag ccacctgggg tctccattcc tggagctccc tgcctggatc
     9061 caggtgtgag ggccaggtgg ccacccagag ggagggctgt atgattctgg gcaacatccc
     9121 caaatggaca gggcagggca tctccaagat gctacttccc acggactctc agaagaactg
     9181 ctaaactgtc cctctgtcag ggcagagacc aagtccctca cggtcaccag tgtgtgaccg
     9241 tgggcctggc acacaggagg ccctcaactg ttgaaccagt gggtgaataa cagggtctct
     9301 aggacagtag ggtgtgaggc agaaaaccca tctatgctca cctgactcta tgaggcagtg
     9361 gtttacaagt tcagagtatt tactatgagc agggcatagt gagtcccagg gtcaaaggcc
     9421 acccagcccc tgcccccggc aggacttgag gagggagaag tggggcacct tccatctgca
     9481 gtggggttgg gagggcttct agaggaggtg gagtttgaat ggacttgagc aggattgggt
     9541 ggggctacca caggcaggag gagcaatgcc aataaggagg gggccaggca ggggctgaag
     9601 ggacctcagc aggggagccc cccttcccgc ccttgccatc acgtgcagga gctcaggtgg
     9661 gaagagcaag acagcactgg gctggggtct ctgagtgagg ggctgggagt tgaggtgtta
     9721 tcctggttct acaaggacaa cctggcactt tctaagcggg gagtaacgca cgcaggtctg
     9781 tgctccagga gggttcagtg gcgtgggtgg gttgtgacag ctgattttca tgagcactta
     9841 cccagtgcca ggcagagtga tgcgtgttaa acacactctg tcaccacatt taacagttga
     9901 gaaaactgat gcacagagag gttgggctac ttgcccaagg tcacccagct agtaagtggc
     9961 agagctgata tttgcaccca ggcactctag ctccataacc cgtaattttc atcagggtat
    10021 gatggtacta cagaggtgcc aggggccaca gcgggaccct ctaggaccgg tgccccaagg
    10081 tcacagctgg accctctagg accggtgccc caaggtcaca gctaagtctg gcttccccag
    10141 gtggtgagaa gacatcagtg gccatctcgg tgctcctggc tcagtctgtc ttcctgctgc
    10201 tcatctccaa gcgtctgcct gccacatcca tggccatccc ccttatcggc aagtgagtga
    10261 cgctcaagcc cggcctcacc ctgcttgcca gcccagccct gggagctcca agctgagtgt
    10321 ttgcccacag gttcctgctc ttcggcatgg tgctggtcac catggttgtg gtgatctgtg
    10381 tcatcgtgct caacatccac ttccgaacac ccagcaccca tgtgctgtct gagggggtca
    10441 agaaggtgag tacttggccc ggcgcaaaag ctcaccactg taatcctggc atttcaggag
    10501 gctgaggcgg gagaatctct tgagcccagg agttggagac cagcctgggc aacatagaga
    10561 cacccctgtc tctataaaca atcaaaaaaa ttagccaagt gtggtggcgc atgcttgtat
    10621 tcccagctac tcaagaggct gaggtggatc acttgagcct gggaggtcaa agctgcagtg
    10681 agctgtgatc gcgccagggc actccagcct gggcaacaga gtgagacctt gtctcaaaaa
    10741 aaaaaaaaaa aaaaaaaaaa aaagaaatga gcactctcaa tagccaaaag ctggagacta
    10801 agccaggtac agtggctcac acctggagtc tcagctactc gggaggctga ggtgggagga
    10861 tccctggaac ccaggagttg gaggttgcaa tgtactatga tcacagttgc accccagtct
    10921 gggcaacaga tcgagacccc atctctaaaa aaataaaata aaatgaaaag cagggaccgg
    10981 gtgtggtagc tcacacctat aatcccagca ctttgggtgg ctgaggcggg tggatcacct
    11041 gaggtcaaga gttcgagacc accctggcca acatggtgaa actccatctc tactaaaaat
    11101 tcaaaaatta gccaggcgtg atagtgtgcg cttgtaatcc cagctactcg gggggctgag
    11161 gtacgagaat cgcttgaact cgggaggtgg aggttgcagt gagccgagat ctcaccactg
    11221 cactccagcc tgggcgacaa gagacaagag cgaaactctg tctccaaaaa aaaaaaaaaa
    11281 aaaaaaaaat ctggaacttg tccaaaggcc atctgtagaa tgggtaaaga cactggacat
    11341 atactcccac gggagtgccg ctcagccgtg cagaagcacc tgcggctgct gcagccctgc
    11401 acgtgtgaac ctcctggcac agtgttccgt gaaagaaacc agacgcagca gcacatgctg
    11461 caggcctcac tttgtaagaa gttcaagaac aggccaaatc agtgtttggt gatggaagtc
    11521 agaatggtgg ctatctctgg ggctgggagg gtactgagtg ggggcaggtg tgagggagat
    11581 ttttggggat catgttcact atctcatcac tggtgattta cccagtggaa tgcatctgta
    11641 aaaattcatc tagctatata cttaagatgt gctcattcca ctgtatgctg caactcagaa
    11701 ggaagaaggg gaggactgag tgcagggtgc tcaggagggg gctgcccttg cctctcggct
    11761 gctgcagggc cggctggctg ttctgggaca gctgaaggca gtttagcaac tctttttttt
    11821 cttttttgag atggagtctc cctctgtcgc ccaggctgga gtgcagtggt tcgatctcag
    11881 ctcactgcaa cctctgcctc ccaggttcaa gtgattttca tgcctcagcc tcctaagtag
    11941 ctgggattac aggcgcccgc caccatgcct ggctaatttt tgtattttta gtagcgatgg
    12001 gtttcaccac gttggccatg ctggtctcga actcctgacc tcaagcgatc cacctgcctc
    12061 ggcttcccaa agagctggga ctataggcgt gagccactgt gcccggcctt agcaactctt
    12121 tttgtctttc agcatttgat gggggagact ctagcatttg gagcatttac cttagttttt
    12181 ggtctttaat taatcatttt tagtgaatgg gttctgctcc gcaccatggg tgatgtggga
    12241 gagctggaag caacctgcat gtgcatcagt aggagatcgg ggaatcaatg acagagtcag
    12301 acgggggagc actttgtggc agccaggaat gaagtcacag atgttaggat gtgtaaaggt
    12361 caccccatgc ttgtaaaatg gcctttttgg ccagacacgg tgcctcgccc gtaatcccag
    12421 cactttggga ggccaagtca ggcagatcac gaggtcagga gagcaagacc atcctggcca
    12481 aaatggtgaa accccatctc tactaaaaat acaaaaatta gctgggcatg gtggcgcgtg
    12541 cctgtagtcc caactacttg ggagactgag gcaagaaatc acttgaaccc gagaggtgga
    12601 ggttgcagtg agccgagatc gcgccactgc actccagcct ggtgacagaa tgagactccg
    12661 tctcaaaaac aaagaacaaa aaacaacgcc tttcttgtgg ccccttgaca tggccccagc
    12721 tcttcctgga gaccctgccg gagctcctgc acatgtcccg cccagcagag gatggaccca
    12781 gccctggggc cctggtgcgg aggagcagct ccctgggata catctccaag gccgaggagt
    12841 acttcctgct caagtcccgc agtgacctca tgttcgagaa gcagtcagag cggcatgggc
    12901 tggccaggcg cctcaccact gcacgtgggt ccccgctggt cttggttttc agcccatctg
    12961 tgggaggtgg gtggaggcag gcctcacacc cactctggcc cctcgtctgt aggccggccc
    13021 ccagcaagct ctgagcaggc ccagcaggaa ctcttcaatg agctgaagcc agctgtggat
    13081 ggggcaaact tcattgttaa ccacatgagg gaccagaaca attacaatga ggtaagggac
    13141 cacaggattg ccatgtacag gtgttcaagt agggcactga ttaagtgtat tctatcttaa
    13201 gagggcaggg ttccccttag aggcacacac caacttagat gagggagtta atgtgacaca
    13261 gattccaggc ccccccgcca gggagagaga actcctgcct ggcaccctat agcagcactg
    13321 gggccaggca cacacacata ggcacacagc tccaccctgt ccaggccaca ctctgagcat
    13381 cccttaggat cccttctttc tcccagctgc caatcatttt ctgtccctac tcagttccaa
    13441 gcctgatact ccagacagaa ccagacattt taaaggtagc catatatggt tattcaacat
    13501 tatacaactt ctaaaaacta tctcttgaga aagggcacct tttcccagtt cacatatggg
    13561 ctggcagcag ccctgacttg ctgagatggg ggagaagaag agaggggtct atccaccttc
    13621 ctcagcccct aggagagacc cctgggcctc agttcctctc tagccccaga gccctgtgct
    13681 acagcagaga gggaggctat ggtctgttcc cgcctcctca acagagtgat cagccctgcc
    13741 tgtggccaga ggggcctggg accttgctgg ggacaagcca gcattatcct gcaagcccga
    13801 ggcagcctct gcaggcacac tgagccgccc tctgcctcca tggctgggcc ccagcttggg
    13861 ggtggggctt tgtggcctga ggcccttctc accccactct ctctgcccct acccacagga
    13921 gaaagacagc tggaaccgag tggcccgcac agtggaccgc ctctgcctgt ttgtggtgac
    13981 gcctgtcatg gtggtgggca cagcctggat cttcctgcag ggcgtttaca accagccacc
    14041 accccagcct tttcctgggg acccctactc ctacaacgtg caggacaagc gcttcatcta
    14101 gggtgggcct gttggggagc caggagacag cagggtctga gagaggagcc acagtcccta
    14161 atgacaccca ctcctagccc tgaggctcgt gcccctcaga ctggggaaga gtccaaggaa
    14221 gggagggagc agccactcct caatgctcaa tggctcccct gaaatcaaga caggggccac
    14281 ccgagatggt ctgagggtgg acatcggcta cagtgggtgg gcaggacgat ttggggggag
    14341 gcccgaggct ggctcagggg ccagggagga ggccactcag ggtggcctca gggggagagc
    14401 tctgataggg gtgagacaga tagggcccct tctctgcttc tcctccccca aggtgtgggg
    14461 tagagcaggc aggaatctgc gccttcactc tctggcccct ccagcctccc tcttcctacc
    14521 tacccttcaa cctcaggctt ctgaggcctc acctgggact gaggttgagg acacctccct
    14581 ccctccagac cccagagtat cctttcctag ctctttctgc cttgacctct ctgcctaggt
    14641 ccctttggga agttgaggac tggagtggaa aggtcaggat cgacatccac aaagacttgg
    14701 ggtcagcctg aggttgcaca cacaatccta gaggaccaga acgcagcacc tctccccaaa
    14761 gggtccctgc cccccagcac ctactcctct ccaaattagg gttgtcatgc attatttggg
    14821 gcatacatat tctaaaaaat cattcgttgt ttctctgaaa tttgtcccct atttttattt
    14881 gctaaatcta gcaaccctat cccaaaggca gcctccactc aatcttatcc tgagggccaa
    14941 aggccaaggc tgcaggaatt gggagacaag ggtctgtttg tatggtggtc cacctccaag
    15001 atggccccag tgatgcccag tattcacacc cttgtgcagt cccctcactc tgtaccaggg
    15061 tgggtctggg taaccaatag aatgaggcag aagtgatggt acctcacttc ccagatttgg
    15121 ttaggaaaga cactatggcc tctttcttgc tcattagccc tcattctcac atcagttgga
    15181 tctctcactt tggggaagcc agctggcatg ttaaggagcc ctatggagag gcccacatgg
    15241 caaggaacta aggcctcctg ccaacagcca cgtgagtgaa tgtggaagtg gatcctctgc
    15301 cccagtaggg ccttcggatg agatcacagc ccagtagaca tcttatgtgc agccccatga
    15361 aagtccctaa gccagaacca ccagctaagt gactcctgga ttcctgaccc ccagaaactg
    15421 tgtgagataa taaatgtgtg ttgttttaag tgacaacgtt ttggtgtcat ttgttacacc
    15481 agcaatgtga ccttgagtga gctgctcctc atctcactcc tcaccttcca tcttctaatc
    15541 tgcaaaatgt gtgtctagta agtcctagtc atggggtgtt gtgaaaattg aatttctagt
    15601 aggagcattt tcatgtgacc tgcacattta atgggtggtg atttaaccca tttccctcag
    15661 gggggaattg gtgacctcat taactcagat atacagaagg tgagattttt aatgtttaga
    15721 tgtaaccaag gaaaaagaaa aaccatttaa aaccaaaact gaccctagta acttctgcct
    15781 tccagcatga actattcaca aaattcaagg tacaaatctt taattgtcct gtctaaatag
    15841 gaaagccagt ttgttctcac acctgtcagg tgagcaggaa atctgagact tccccaggaa
    15901 tagcccatca actcagggag ggtccgtctt gtgcacagag agtctagggc cctcagccac
    15961 agtctttgct tctctctgcc tcatggtggc gctgctggca gcaggtcttg gttcaaccac
    16021 caggtgagtc ctcagttcta ttaggccctg ctcaagtggc tgtggacttc cagagaagac
    16081 aaccccaaaa tgtcacacaa aaccgggggg gtgcctcctg cacaggctcc cagggtcacc
    16141 acagtttcca ccagaggcac ccactccccc agcacggtgg tgctgtcagg actggtccac
    16201 tctgactgac atagaactcc atcttctgtc cccaggaagc catgctcaca ggcacagctt
    16261 tccgggaagc cagagagtgt tcct
//

