LOCUS       NG_008797              19956 bp    DNA     linear   PRI 25-JUN-2010
DEFINITION  Homo sapiens caveolin 3 (CAV3), RefSeqGene on chromosome 3.
ACCESSION   NG_008797
VERSION     NG_008797.1  GI:209969774
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Johan den Dunnen. The reference sequence was
            derived from AC068312.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a caveolin family member, which
            functions as a component of the caveolae plasma membranes found in
            most cell types. Caveolin proteins are proposed to be scaffolding
            proteins for organizing and concentrating certain
            caveolin-interacting molecules. Mutations identified in this gene
            lead to interference with protein oligomerization or intra-cellular
            routing, disrupting caveolae formation and resulting in Limb-Girdle
            muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling
            muscle disease (RMD). Alternative splicing has been identified for
            this locus, with inclusion or exclusion of a differentially spliced
            intron. In addition, transcripts utilize multiple polyA sites and
            contain two potential translation initiation sites. [provided by
            RefSeq].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19956             AC068312.5         58571-78526
FEATURES             Location/Qualifiers
     source          1..19956
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p25"
     gene            4991..17956
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /note="caveolin 3"
                     /db_xref="GeneID:859"
                     /db_xref="HGNC:1529"
                     /db_xref="MIM:601253"
     mRNA            join(4991..5181,16717..17956)
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /product="caveolin 3"
                     /transcript_id="NM_033337.2"
                     /db_xref="GI:299115915"
                     /db_xref="GeneID:859"
                     /db_xref="HGNC:1529"
                     /db_xref="MIM:601253"
     exon            4991..5181
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /inference="alignment:Splign:1.39.8"
                     /number=1a
     exon            5001..5181
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /inference="alignment:Splign:1.39.8"
                     /number=1b
     CDS             join(5068..5181,16717..17058)
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /note="M-caveolin"
                     /codon_start=1
                     /product="caveolin-3"
                     /protein_id="NP_203123.1"
                     /db_xref="GI:15451860"
                     /db_xref="CCDS:CCDS2569.1"
                     /db_xref="GeneID:859"
                     /db_xref="HGNC:1529"
                     /db_xref="MIM:601253"
     exon            16717..17956
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /inference="alignment:Splign:1.39.8"
                     /number=2b
     exon            16717..17064
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /inference="alignment:Splign:1.39.8"
                     /number=2a
     exon            17161..17956
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /inference="alignment:Splign:1.39.8"
                     /number=2c
     STS             17348..17963
                     /standard_name="CAV3_2400"
                     /db_xref="UniSTS:462792"
     STS             17800..17929
                     /gene="CAV3"
                     /gene_synonym="LGMD1C; LQT9; MGC126100; MGC126101;
                     MGC126129; VIP-21; VIP21"
                     /standard_name="RH92828"
                     /db_xref="UniSTS:90920"
ORIGIN      
        1 cacagggtct gcaaactgca tacagcccat gagccaaaat cgtgttttta caatctggct
       61 gccacttatt tttgtaaata aagttttact gagacacaac catagcccct tcatttacgc
      121 attttctaca gcagcttttg agctacaagg gcagaggtga gtagtcgcga cagagaccac
      181 atggcccacg aaatctgaaa ccagggcagt gcaacccata gggccccatg cttgggagat
      241 gccacagctt gatttcacca tgttgaaatt tttaatcatt tttaaacaag agctgaattt
      301 ttgtttttct ctggacccct caacttatat agccagtcct gcctgaaaga tttactatat
      361 ggtcctacag tttgccctgt tcttctcctt ttttagctct tggttccctt tcactcttct
      421 accttaatgt ttctggaccc aggaagccag cccctttcgg aagcagtcta ttatatctct
      481 gggaaacttt gaggcagtcc ttcctggtac ccttaccgag aactatatca gctatcatta
      541 tcagtggggc caacgatgac ccaggccctg ggttgagtca agcgaaagtc tgccacttac
      601 tcaccagtcc ttgggacctc ccagaataaa tctcatccct tatgccttca gagatttgag
      661 gaaagttctt ccgtccctct ctctgagtct tctctttaga acccaaaatt gtctgtttct
      721 cacaagacat gtttcaagct ctttcttaaa ggagcttcct tcctctatag agatgatcta
      781 gtttcccaac acccctcttc aagcatggag ccccactaga cctccaagcg tagtctgacc
      841 agtgcacagt tgagtaggac agtcacctcc attattctag agtgttcatc tctattgatg
      901 catcctaaga tcactctgtc tattttggaa cccattccaa aaatctccca gatccctcat
      961 ggtaggaaaa gatggtccgt tatgctcatt atataggtga gtaaaccaaa gtttgggagg
     1021 gagtggcctg ctcatggaca tatagcagtt ctgtctccaa atcccaagct ctccagtcca
     1081 ccaactgaga tttttgggcc ctcggtttct acatctgtaa aatggaaaag ctgggtctct
     1141 tcgagctcga gcatactgtg atttgttttc taaatgcaga ccccaaaagc caagtcatga
     1201 agaaaacaga agctctcaat ccagatctaa aacttgtagg aaaaacaaaa aaaagcttcc
     1261 tttcctgctg atcattctag agttactagc cttggaaaca tttgcatgag tgatcaatct
     1321 tgcttgttaa cagtagccct agacttgtta gctcactgag ttttcagtcc atggtaccat
     1381 tactttctta gtgactcagc tcatgtaaat ctttcccttt cccattactt cccctttgga
     1441 ccctccacaa atgtgtcttc ctgcacatcc cattttcaaa attcttttct ctctcttttc
     1501 cctggcaagc caaataacaa caacaacgac aaaaatcctt tgaaataaga acgctgtgtc
     1561 ctctataaaa ccccagatac aaaatgggct ccggaaagcc actctctctc cttaattgct
     1621 ttctcttgtt agctgcatca ccccagggtt gacttgaaag tttcatctgt cagtacgttc
     1681 tcttcgtaac attttttctg tgagtacaca gcccctctgg tgccccatta ggttttccca
     1741 ctgagtgcgg gggcacagac tcatgcgtgg ggaatacagg caggttttac catccaaact
     1801 tgacaaggac cccaggcctc agagaggggg ctcagagttg cttcacgata gggccaagaa
     1861 acaactaatg gttcccggct tcagtgctct tttcaccagt gaggttttta gaaatacaat
     1921 tgtcataaga aagtgagaga tgaccctttc tctgcctctg gcatctggcc ctttcctctc
     1981 tgcctctctg agtccactca tccttctggc ccagctgaag tacacttcct tcctgtgaaa
     2041 tccacaatgt gtgttagttg ctccactccc ttggccctca gcaccgatca ccagctaggg
     2101 gcactgaccc tttcagataa caaatgagcc tccttacaca caccaaggat gcctaggaag
     2161 gaagccaagc acataatgat tctcaacaaa cagtagttgc tattgccatt agcgctcatt
     2221 gatccagtga ctatggttgt gaaacaagct cccccaaatt ccagtgacat aaaaaaatga
     2281 ttatgatcat gaactgtgtg gtttagatat tcaaacagga cacagagaag acagtttctc
     2341 tgtttcatgg tgtctgaggc ttcagctgga agacaggaag gttggggatg acttgaagac
     2401 tggcgactgg gaacatccaa aactttgttc accctcatgc ctgatgctga tgttggttga
     2461 cagctggagc ctcagctcct ctctatgtgg ttttcccaca taggctggtg tggacttcct
     2521 cccagcgtgg tgactgaggt ccaagagcaa gaatcctgag aggagagagc caggaagcca
     2581 gccagggagg gaacacagac cctccctctt ggtggaagga gtgtcaatct catcatcttt
     2641 ggaaaagatg gccttccata atcattatta ctatgtcgtt attattactt cccctttagg
     2701 atgatgagtt cttctaggtg gctcttccat ccctggcgac aagactgcca ttagctggcc
     2761 cacctttcac cagacatatc tggttctacg gtgcacaaag cttaagctca ggcttagatc
     2821 cctgccacgt cccttgtgaa tacaagcagc aatgttcttt ttttttgtta caatctcttt
     2881 gcagaatatt catgtacctg ggaccagggg gacctgggga cccaggcaag ggaatggaaa
     2941 agcaacaaaa aaagttacct cttaatccta agcgacttag ggacagtttt ctggttgccc
     3001 accatttatc cctagtaaca ctgtgggggt gccgaaaatg tgctcaagct aaaaaaccta
     3061 cagttccatc atcgtttgcc aagacaggag tgaccaatga gatataaaca gaagtagttg
     3121 ggttggactt ctaacaaagc tttataacag agccgactca gttcgcagat gtcgtttctt
     3181 gtccctgccc cttcctcttt cttcttatcc agactcagag atgatgattg gaggagcagt
     3241 agacatcttg tgcctatgag gtggctttcg ggctagcaga acagaaggat gggagtccag
     3301 atgtctgaag acatcatgga gccactataa tatttctgaa ctacttgtgt taagtgagaa
     3361 aaaaagttcc taccttattc aagtcactat tacttttgca tcctttgtgt tactagccag
     3421 gtgtaattat tgataaagcc taaatcacct ctggttttcc ccctcctacc tcaaacttca
     3481 cccagctcca atccaccctc cacctggcca ccagggagct tcctcacaca caaatctgat
     3541 accgaccctg tcctgctttg aagccttcaa tggctttcca gcacccctag acaaaatcca
     3601 cattctttag tatgacattt gggatgctgc acacccaggc ctgagctgag ctgtatctcc
     3661 tgcctcaacc ccagacaccc tgtgctccag ccactccaca cttttcaaca ttcctgtcta
     3721 taccactcct caatatccac aatcctgtaa cttgaagtgt tctaggtgct gagctcctgc
     3781 ttgtcattcg atacctatct gcaaagccac ctcccacagg aagtcttccc cggtgtcctc
     3841 agagtaagtt actgactcct atggacttct aagaccagct ctttgtaaaa tatctctgat
     3901 ctgtggcact taccgcacag tattataatc acttattgtt ttaattagtc tccccacctt
     3961 gactgggagc acttcaaggc ggacagagcc ttgttggtct gtttatcccc agctattagc
     4021 aaatcctgaa tgaaggagtg aatagacagg taaatggaag cacagaccct gacccctgag
     4081 gattcagagt tgccatcctt catgctgctg gagcccaggg gaaggctgag ttagaagagg
     4141 gcacagaaaa accgagcagg tatctaagag aggtgcaccc cactgatgca tgtggagtgt
     4201 ctgggaccca agaaaatcct ggaagctgtc actagggcag ggtgaagggt agcacgaaca
     4261 tggacttcat gttcccccca ccgggcatat cccagtgcag gctccagacg gcagacgagg
     4321 ggcagcccca cagcagcttc ctctccctgt ttcatcccca gcctggcccc acaccacagt
     4381 ccatcaactc ctgctccagg tggaaacctc agaaacccac aaagctcgga cctgctccag
     4441 gtcaccaagc agcagggcca ggcactggca atccaacgag aagccccact acatcgcatt
     4501 ccagctcctg aagccattcc ctgggtagga gagccctgat tgttattatc atctctccat
     4561 tttacagatg gggacagagt ggcctagaga ggtgaagtgt gccaaaggtc acacagccag
     4621 ccagaggcag aggagggact aaccccactt ccctccacgg gcagtgcacc ccaaaggagc
     4681 caaaatgctg acagcagtgg ggcaaattcc aggggccccg gagcgaccgc cgagttggcc
     4741 acagccacac gatgcatagg aaacgctagg ccctctgcac cctctcctga ggcccagtgc
     4801 cctgaggcag ccccctttaa ggagcgatcg gccttccaga agagctccag tcttaatttt
     4861 agcttggagg cctgccacag gaggctttag agagaggcag gctgaagtta tgtgggacag
     4921 ctgtcagccg gcatgctggg tggggcctat ttagctggca gggacataag tctggggaca
     4981 ctgaattggt ctctctgccc caagtatttt cagccccagc cggccacaca gctcggatct
     5041 cctcctgtgg atccccccag ctctgcgatg atggcagaag agcacacaga tctcgaggcc
     5101 cagatcgtca aggatatcca ctgcaaggag attgacctgg tgaaccgaga ccccaagaac
     5161 attaacgagg acatagtcaa ggtaggctct gcaggcctgc ctcggcgggc ggagagtgtc
     5221 aggtttgcga gacgtgggcg cttggcaggg gagggtatct gctgcagaca cagtttccct
     5281 gaaaagagac ttgttgctct gttgtctctg tatcaccccc ccaaccccac cccaccccca
     5341 aaaaaaggct tctaaatcac cgaaggatct ttagcaaaat caagagcaaa aaattagcct
     5401 catctccatg acctaagtgc taatcagggc aggaggagcg agtcacaaag aaaatccctc
     5461 cttactactg tgacgctcct gccactcact cctggctctc accctgggag gaacaggaac
     5521 gggcggccaa gttgggctcc tttctgtgcc aaggggcatt tctgcggtct ctccagtggg
     5581 tgcagggtta atccccagag ggcagcttcc agcagggccg gcagcccctc gaggtacact
     5641 cactccccca gagcactgcc caatatctgt ccccaaggcc gagggccatg cccagccctc
     5701 ccctagctac cccctcaccc caggtctagt ggccaggaca gggcagacgg cacccgggac
     5761 cctcgaagag aaagctcggg gttgtctagc cctcagggag tctctcagcg tctgaagttg
     5821 ggcctcttcc ctcgcctcct ggtgacacta gcggccctgc tgcctccagg cccacacctt
     5881 caatccaact tccagccagt acccagaggg atctttcttt tttctttttg agacagtctc
     5941 tctctgtccc caaggctgga gtgcagtcgc acactcacgc ctcactgcag cctcaacctc
     6001 ccaggctcaa gtgattctcc ctcctccacc tcctgattag ctgggaccac aggcgagtgc
     6061 caccatgccc agctaatttt tgtattttta gtagagactg ggtttcatta tgttgaccaa
     6121 gctggtatca aactcttggg ctcaagtgat cctcctgcct cccaaagtgc tgggattaca
     6181 ggtgcaagac tccacaactg gctcagaggt acctttctaa agcagaattc ctccaagaag
     6241 ggtccccagc caccagcatc tgagtcactg gaggggctgt taagaggcca gtgtctgagg
     6301 cctctcagat cctactgaaa gcattggaat ctcaggccag tgctgtccaa tagggatact
     6361 gttaccacaa ggaatttaaa attttctagc agccacattt taaaatgcga aagcaaacag
     6421 gtgaaattaa tgttcctgat atttcttact taaccctata tatctaaaat agtattattt
     6481 caacatgtaa gcaatataaa acaattatca atgagctatt gtacagtctt caagtttgaa
     6541 atccagtgtg cttcctatac ccacagtata tttcagttca gaccccacat tttcatccga
     6601 aatgcttgtt ctgcatttag atttcataaa atgtacatgt gaaaatcgat tcgcatgcct
     6661 gtactgtttc aaacattctg caaaaatttt tcaataatga aatcggggtt tacattttaa
     6721 ttaaagttaa acaaaatcta gaattcttca gtttcactag ccacatttca agcgctcaaa
     6781 gctcctggcc actggatcag acaggcctgt attgcggtct ttcagtgggg cacctcccat
     6841 gctggagaag cctagcctct ccacgtggct gtccaaaccc aacacaatct ggccccaacc
     6901 tgcttcttct gcctggttgg ctcccacctg ccagcccacc caccagagta cattcctgtg
     6961 ccattgccag aagtgcctgt cctctcttct ccaggtggtg aatgcctcac tcagccttca
     7021 aggcccaact caaatgcaac ctcctccaga aagccttccc tgactcctcc aggcaattag
     7081 ttgctcccac ttctgtcccc ctgcttcact cagggcattc ctccaccaca gctcttctta
     7141 tactggatat tatatttcta tacatcgtta gtgatggaga tagagtatac agtatagcac
     7201 agtgtgaaag ctgaaatgag gaaaattagg aaacaaattt cacaaactgt aaagcactat
     7261 atacatgtaa ataaaattgt acctgtaaaa tattattagt tatggtttcc atcagtgtca
     7321 tctagcagga atagtcctgg acttgacttt aatagacttg atttcaaatc cagtccattt
     7381 tacctaaaaa tgataacact ggacaaacca actaggtttt ctgagactca gtttcccctg
     7441 taaagtggga ataatatcat ttcccaattt acctccacca ggtaaacgaa tctcaaagca
     7501 gcactgtgcg ttagaaatat agcatgagga ttgaatgaga tgaagggttt gaaagtgtct
     7561 atcacagtcc ctggcaccca gcaaggatga gacagtgtga gtcaaagaag ggtctcaaag
     7621 agcttgcagt ctagagggca agagagctaa gccaggagcc tgcgtcatgc ccaggtagcc
     7681 atctggtaca cccaggtggg ctgcagggag atgggaaaga ggatcccacg ggagaacatg
     7741 gtttctaaag ggcacccaca atggctggta agtacagagg gagcccttgg atccctctga
     7801 gccaggaggg agccagctcc aagccgcagg cctggattat gacgcagagg gagcggcggg
     7861 ggcggcggca caggtgcagc ggctttacgc agccctcctg gggctgagag ctgtcctctc
     7921 ctggaggccc tgagccctag caaaaatagc aaaggctaag aaaggatgcc gcaaataatt
     7981 ttgtccagag gaggtggtta tttggtatgt tttggacatt ctctgcttta gggatttgtt
     8041 tgactttttc tttcttttat ttttagtgag tgagaaatga aaaaagttaa tgcagaacaa
     8101 ggatcataaa gcagactcag atatagatca caaacaggtt taggtagatt tcaggtctct
     8161 gttacagtct gttaaagaat aaagaaaaga aagaaggaga gaggggactg tggctaggag
     8221 ggatgaagcc agactgttca gcctctcaac tgcccgggtt ttgccatcga tggaggaaaa
     8281 gagagatggg aaggaaaagg gaatgaggga gacagagaga gatggagaaa ctggacagag
     8341 actgagagga aggtgcagga ggccctggca gtgccccagg tggcaggtgg cagggtggcc
     8401 tcacaggtgg tagcaggttt ctcatgggct aggatgagtg acacggaaag aatgctggaa
     8461 taggacctgg ctacagactc aagttctggt ccaagacctg acagtaactt gctgtgtgac
     8521 tctgaggaaa tcctttgccc tctctggtcc caagtccctg gtgccaccag tcacggccgt
     8581 ttcacattta aaaaagccaa ggatgaagag taggagatag gcatactaca tccatggatt
     8641 tgacccccag tagaggggag gcaccccttt ttggccctgc ctttaaaccc aggcagccaa
     8701 gaacagagga agagccctgt atactccaac agacttcagc tgtggtctcc aaggctcggg
     8761 actgggccca gggcagtgta gaaggtcatg gagattgtag ctgaggaact ggggggagca
     8821 cacccccatt tctgttgcca cttgccctcc tcaccaacac tgattccaca aatcgcaact
     8881 gaatgcctgt tcagcacagg caatgtgctg tcccagagga cgtagtgatg agcaggacag
     8941 cctcactgca tgcaaaccct ccaggctgca ggggtgggaa tgtctgccaa aggtccccag
     9001 ggctctcagc tcaccagcag gtacacccaa ggttgcctca accttcagac ccaggttgga
     9061 aaggtcctag ccccactaca ggtatacctc agcacctcag agccacccca cagtgcctcc
     9121 aagttatttc caagagggct tagggccacc tcactgacag catgctctct ctctctgctc
     9181 tctcttctct ctctctcctc tttcttctct ctctctctct cctctgtctt ctctctctct
     9241 ctctctcctc tctctctctt ctctctctat ctccctttct tgactcacac ataggccccc
     9301 agggccctaa agcagtgatg cttgaacctg agagttatgc aggtatccca gcttctgcag
     9361 tcaactcctc cctcttgagc ttctcccaag ttgcccttca agcaggggaa ggagatagat
     9421 aggatcccag cctctccatg atactactcc ccaaccccct ccacccacat ctgccacaga
     9481 acgcctgcct tcttcagaaa aacaaacacc catttgcccc ccggctcagg ctacacaaca
     9541 cccagaggaa ccagatgccc accagcccta caaacacttg ttccaggttt gtgctcatca
     9601 gggacaccct gttgcacaaa gaagaaactg acctggtacc tcccttggcg gggaatccat
     9661 tcctggggag aagatgagag gagaacaatg agaacataca ggagaaggag ctgaacaccg
     9721 taaatgagtg ccaggttagg tgtcatggga ggttaggaga ggaagaatta ctttcatctg
     9781 gaaaaatcag aagccagcta tatggacagg tggtatccat ggtgcatcat aaaaatgaga
     9841 aaaattaaaa atgtgaaatg gaggaacaaa gctttccaag aagaaatgga ataagcaaag
     9901 gctttcccaa cactgggaag aatgttgggc agagttggca aacgtaagag gctgtcatta
     9961 ccactgcccc ttccagtgtt catggcagac atgacaatgg atcacagcac tgctccatga
    10021 ctaatggatc acagcactgc tccatggaag ccatgcacca tcagctagtc atagtgggta
    10081 caacagataa cacttcgctg ctctgtctgc agaagaataa tgaactatcg aagaggatta
    10141 ggacagagga tctgaaaggg aatttgtggg agagaaggca ggaagggcag gttgaaacta
    10201 aataatagag ggtcatccaa tccacctgtc attccatatt ggcaattcct tccttttgga
    10261 aatgtcttgc cctctgtcaa tgacctctaa gaagagctgc atcagactaa ttcacactga
    10321 ggtattacaa cttagtgtta tgaggactcc tgggtatcaa ctgatctaga gtttttcaaa
    10381 atgcagtcca ctttcccagg gtccagtggt gggggcactt actaaactgc agattccttg
    10441 gccttgcccc cagaagttct tattcagctg agctggtgaa tgtttacact ttaatgtttg
    10501 agcataaaag tttcatgctc aggccaggca cggtggctca cacctgtaat cccagcattt
    10561 taggaggcca aggcaggtgg atcacctgag gtcaggagtt caaaacctga ccaggccaac
    10621 atgatgaaaa cctgtctcta ctaaaaatac aaaaaaaaaa aagagccagg tgtagtggtg
    10681 ggtgcctgta atcccagcta ctcaggaggc tgaggcagga gaattgcttg aacccaggag
    10741 gcagaggttg ccatgagccg agatcgcacc actgtattcc agcctggata acaagagcaa
    10801 aattccttct ccaaaaaaaa aaaaaaagag tttcacgctc aaacttgtca gcttgtcagc
    10861 aaccaagtcc cattcatcct atagaagaca cctggagccc agagttatcc cttgttttcc
    10921 ctaaagacag actgtatcag ttatcaattg tgagtaacaa atcattccaa aacttaatgg
    10981 cttaaggaaa caaccatttt tttatttctc acagttctgt gggtgggcag ggctcagctt
    11041 ggcagtcctg ctggtcccac tgggggcctc tcatgcagct acagtcagat ggtggctgag
    11101 gctgcaatca cctgggggct ccaccgagct agaacatcca agatggttca ctcatagccc
    11161 tggaggactg gcagagatgg ctgggaggca cagctgagct gtggtgctgg ggtggctggc
    11221 cctctatctc catgtagttt caggcctcct tattcacatg gcctctccat tagtctctcg
    11281 agcagcattc agcagtgcat ttctaattct gctagtctcc agagcagagt ataaaagtgg
    11341 acttctaaca tgggggctca gtgctcctaa aagcagaagg tgctaggctt tctgaaggct
    11401 tagttctaga actggcacaa catcctttct gccacattct tgtggttaaa gtgagtcaca
    11461 gggcaagccc agactcaaga tgggatgaga ctacctgagg acaaacaccg agaagcatga
    11521 ctaatggagg gtcatctttg gagaccagca aaccacccac tgaaagctcg tgcacagcca
    11581 agcccagagc tccacccagg gtacttctat tcctccctat tccaatatgc accaaatttc
    11641 ttgaaggcag agattgagag agcagaagag cggatgggaa gggacaggca gtgaggcaaa
    11701 gatcagggct tagtggattg ctgaggagct tcttctggca ggttcttctc tctctgtctc
    11761 tctccttgca gccctctgtt atctcagtct cttcccagct cctttacata aaaccaagtc
    11821 ctgttatgcc ccagcccagg tgtcctaggt cccttaaggt agacctggag ctgaaaagag
    11881 aggctggagg gaactaggat gggggtagat atatggtcct acctaggatg ctctcaactc
    11941 ctagagcacc ctcctgaagg aggagtcaca gatgttctca actccaagct ccagatgatg
    12001 cctggccacc tcctccaccc atcagagcca gcctatgctg tgttctggcc tcaggccctg
    12061 ctggggtatc tggccccttc aatcaccctg ctgtcaggct gacctgagcg tcactctgcc
    12121 agtcccttac gtgccatgtg aaataacaca tgtaagatac atggccccaa actgacatgc
    12181 ataaagggcc atatacatcg tgggtgttac catggttatc ccagattgta cacagttgta
    12241 ttcttttgtt gctacctttt ataacaaaag atgcagagct ttgtcatttt tacagttttt
    12301 gcagctatca cctcatttta cttcctactt tgtaggccag tgcctctaaa actgagtgaa
    12361 ggaccagttt taatattatt attctaatcc actgcacagc tatacttttg caaaacgcaa
    12421 caaaaattaa tcactggaaa aatgaaatga aaacagccgt acagttacaa gcaccaatgt
    12481 ttattgttag attcaataaa cataaaatta ctgcatcaaa tttctatgaa tatttctaag
    12541 cactctcaac ttctataatt accttgttgg gagacaggac acactgattg tgaactgcct
    12601 tttaagtagc aaggtaatag gggaggaagc tgggatctgg caaaagctaa gcctctcact
    12661 tgggttttct gactctgaag ctaactccgt gtcattacag atcttggccc aatcgtctct
    12721 gtgtagagtt gaaaaaagaa aacaaacaaa caaaaaacct aggatctcag agagggaaag
    12781 taccatgccc caaatcatac agtaactcaa tggccagtgg atactgggac catatacctc
    12841 cccaccctgc taagagctat ttccccaccc acagatatcc tatttgaatt gtccaaggtc
    12901 ctggatgcct acggactgag tcatgcagga ctctggggga ggtattttcg accccgggtg
    12961 actgttgtcc tcccccgcat cctcaagcaa tcccccgccc tgctatccta caccttcccc
    13021 gccctctcag agactgcggg gactgcgctg gctggtttca attaatcaac tgggtctctt
    13081 gctgttccaa aaataaatat gccacagaag gggacaccga cagaatgtgc accatcgttc
    13141 ccccttcctc accctccagc ccctctctcc aactgcacac agtgtcctga gcctcagcac
    13201 gcagatgcag gctttcagcc caccaccctc caagaaaaag ccatctcctc tcttctggaa
    13261 aggaattaag aaatgaagtc accgtatgct tgtgctgcat ggtacagctg cctagagctg
    13321 cctgagccgg gccttataaa tatctcccca aactagcatg ctgtggccaa agctctctca
    13381 atgctcaaat ctgagctagg ggaacagctg cctcctccaa gcccagccca gccctctgag
    13441 agcatgtttt ctgagattca cagaaaatag agcacttgcc ccacacacag cacccaaagg
    13501 caatccctgg aaataattca aatgttagca ccaatggctt ctgcaaacac caaaaaaaaa
    13561 aaaaagaaga agaagaagaa gaaagataat taaaagacac atacagaagc cattggcggt
    13621 aggattatta ctgtaagtac tgtacttact actgtaagga aaggaggact ccatccgtct
    13681 tatcagcaca gactgagaca cacgcagact catttataac taagtaggct ggagaataat
    13741 ccgggatgtc aaaagaattt ctcagatgta ttttcgagga atcttcagag cacctgaagg
    13801 aataattacc atcactgagc aatattacca tcacaatagc caggcattgt gctaagcact
    13861 gctcaagagg tagtgtgcct gggcaaagtg ggtaatcaat cagtatttat ttggatgtgt
    13921 gggtgggtgg atggatggat ggatgaaagg atggatggat agatggatga tagatgagca
    13981 ggcagatagg tggatagatg gatagatgaa tgagtggata gatggtgagt gtcagtctgt
    14041 ttttcattgc tataaaggaa tacctgagac tgggtaattt ataaagaaaa gagatttatt
    14101 ttggttcatg gttctacagg ctgtataaga agcatggtgc aggcatctgc agctggtgag
    14161 gcctaaggaa gcttccaatc atagcagaag gcaaaggggg agctggcata tcacatggcg
    14221 agagagggag caagagagct gccgggttct tttaaacaac caggtctcat gtgaactaac
    14281 gagcaagaac tcactcatga ccacagggag ggcaccaagc catggtgaag ggtccgcccc
    14341 catgacccaa acacctccca ccaggcccca tcttcaacac tggggatcac atttcaacat
    14401 gagatttgga cgggacaaac atcctaacca tctcagtggg ttgtggatgt atggatgaat
    14461 acatgaaaga aaaatgatct cagtcagcag gatccaggcc ctgggggttt gactagaacc
    14521 tccataaaca tggggagtga atatgacttt tccatccctg ttccaatccc gaagtcccct
    14581 aaattcccag ccagccacca cctcctggaa gccctccaag aagaagtaac atccttcctg
    14641 agaagatgag gcccattttc ttcctctcct cccatccaca gggttgcata agagattaag
    14701 tcatctctga tgaaacctgc agcagagaaa gctgggggcc aagattatac aaggaaggtc
    14761 ctgggaggtc agcttttcca tttctcctgc agcccagagt ctcaccctgt aaactgtgct
    14821 gcctgctgac acaccacccc gagtgaggcc tcatcctcag ggatccccag cctcagagca
    14881 cagggggatc agggacctga ggtggggtgc aggagctcag aagctaaagt cacatgagaa
    14941 aagagggccc aacactgtct gagcaacatg gttctagtca cttctttccc cagaaaatat
    15001 tgtactggaa agaaatgcac caaaacaatc atatctttag taatagagaa gtacaaaccc
    15061 aagactcttt tcttttttct attctgttaa ttctctgtga tatggccatt ttttttataa
    15121 tgaaagtaat tttaatattg gtgatgcaat agaggagagg atcccctccc cataaccaag
    15181 gcgggaaagg gactaactaa ccaggaagat tgaagttgga gcctcagccc tgcaggccac
    15241 cacacaggcc cctcctgttg atctgattag tctgtacctg catccacccc cttttaattt
    15301 gaatggccca ggagcactgc tagaaagaaa acatctcaga acagtttcag gcattagcaa
    15361 acagctctgc aacctcccac ttggcgggct gtactggtaa caaccatggg gagaccagtc
    15421 atgaagcagc taatttggtt cactgctgtt taattgacca gtggaatttt tttttttttt
    15481 tttttttgag atggagtctc gctctgtcac ccaggctgga gtgcagtggc acaatctcgg
    15541 ctcactgcaa gccccgcctc ccgggtttat gccgttctcc ttcctcagcc tcccaagtag
    15601 ctgggactac agacacccgc tgccataccc ggctaatttt tttttttttt tttttttttt
    15661 gtatttttag tagagacagg gtttcactgt ggaccagtgg attttacagc ctcccatcct
    15721 ttcatcctca tgataccact ggaagacgtt cattgactcc atcttacaga caagacagct
    15781 gaggcttagt gatgctaagt gacatcaccc atgtgtaggc agctaggaag gtgcttcatg
    15841 catagcaggg ctcgagagag cttaggtaag cgatgtgagg aacctctgcc tgttcaccat
    15901 ccaatccaca ggtgctcagt aaattgctgt aggatgcata cgaccgtcca acacccttca
    15961 gatcataaaa caatagaatt tgagagctgc gactatagca ctgccactaa gtcactgttg
    16021 gctttaagca agtcgctcac cttgaggggg ttgaacgagc gtgttgtgtt ggtcagcggt
    16081 gcctaggaac agcagcagct tgggctcaac agggagcttg ttagaaatac agagccttag
    16141 gccccactcc agacttgggg agtcggaatc cctggggcga tgatatggtc tggatctgtg
    16201 tcccctctaa acctcatggt gaaacataat ctccaatatt ggaggtgggg ccgggtggga
    16261 ggtgatcgga tcacagaggc agatccctcg tggcttagtg ctgtcctcac aatagtggga
    16321 gagttctcat aagatctggt tgttgtaaag tgtggcactc caccccctgc ccagctctct
    16381 ctcttgctcc cactctcacc aggggagacg cctgctctcc cttctctagc catggttgaa
    16441 agctccctgc ggcctcacct gaagccaagc agatgccagc accatgattc ctgcacagat
    16501 cacagaccca tgggccaatt aaacctcctt tctttatcaa ttacccagcc tcaggtatgt
    16561 ctttaaagca atgcaagaat agcctaatac aggtagggtc cagccaccaa ggttaacctg
    16621 acctctaggg gattctgaca catgcacgca cacacccaaa agcttgagaa gcgggtggct
    16681 tctgtgagtt gaggcttccc cttgccaccc ctgcaggtgg attttgaaga cgtgatcgca
    16741 gagcctgtgg gcacctacag ctttgacggc gtgtggaagg tgagctacac caccttcact
    16801 gtctccaagt actggtgcta ccgtctgttg tccacgctgc tgggcgtccc actggccctg
    16861 ctctggggct tcctgttcgc ctgcatctcc ttctgccaca tctgggcggt ggtgccatgc
    16921 attaagagct acctgatcga gatccagtgc atcagccaca tctactcact ctgcatccgc
    16981 accttctgca acccactctt cgcggccctg ggccaggtct gcagcagcat caaggtggtg
    17041 ctgcggaagg aggtctaaag ccaggtgggg caacagcggt ggcagggcag ggggtggtgg
    17101 gccagactgg tccccggggg acttcttcac aggggctgct ggcgagctct ttctctttag
    17161 ggactgctcc ataccccatg atggagcaca cggtgtaggg aagccagaaa gaaaagacgg
    17221 cccagccaca gaagcacaat ggcccttcgc tctcccccag ccccaccatg atgcccccat
    17281 gcctgggcgt gggggaagat catttgccaa gaggcagcta ctgcaagtct ttgcgttcac
    17341 ttgtactgta acaacataaa ccagcacgcg gttcccaccc ggggccaacc tctccacgcg
    17401 cactcaggaa agtgaccagt gaccactggc gttaggaagg tggctccagt aaagggtttt
    17461 ggctgcattt ggggaatgct gcattttgtt cgtgcctgta agattggttt gtgtcctgac
    17521 cagctccaaa aatatacttc actgccctga aaaacagaca cagggagagt tggttgtctc
    17581 ttcacttggc caaatgtaag tgaagaacag agtctttttc ttcttcggat tctattgttt
    17641 gctggaaccg tacacgttcc ttggaagatc atgtttaagt gactcctgtt gcctgagcac
    17701 aaaaatgggc accaatggag gaaaatgacc cttgggctgg caggggcagt gacccttcca
    17761 gggtaccact gagggaaggg cctgggttca agcctcccgg aacctcccct ttggctaacc
    17821 gagcccctga aatgcccagt actgccattt gacatgaggg taccttcgcc ctcaggagat
    17881 gtgacgaagg aacaaggtct aatttgtgcg tgtgtggact cactatggaa ataaaatgca
    17941 gtagaaagag catgtatcac ttcctccctc ctcacactct ctctctctct cacacacaca
    18001 cacacacaca gtgcccttat cttctttagg gctgtctttt ccgagtgtgc tatccagaac
    18061 ttagccatta aaaaagaaag gatggggatg ggtgttagca tctgtggtcc ggttctttca
    18121 gaaatgctgt atatttctct cagagatttt caatagactt tggcacatta aaggctctga
    18181 catgtcctgc agtagataaa cctgtttaaa ccagtatccc cccaatccta tctgaccttt
    18241 tttttttctt tttttctttt catgcaacgc ccatttaagt ctcatataat taaagttcca
    18301 cagcacttgt caggttttcg gagacattat tcatgcctgg ccacgagccc agtggtcttg
    18361 ggaggcagtg tggtgaagtg gaccacacac agcttgggaa ctaggacgca ggcagccttg
    18421 gttctagtcc tgcttccgct cctagttgcc ttttctgcct caattttatc acccacaaat
    18481 tgatctctaa tgtgcatttt ggctccaaaa ttttacccaa ttttggtttt ctcctaacat
    18541 tgtatgtaaa tttcaaacac agaaaagttg aacagctaca tacccatctt ggctctatca
    18601 ttaacgtttt tctaccccag ctttcttaca tccctattca tctatccacc cctctatcca
    18661 tcccaccaat ctcatcttta cgcatgttta aatacgttgt agagatcagc acattttacc
    18721 cctaaacact tcatcattta gcccttgttt ctgcagatga gaaagttaca gtccagagaa
    18781 gtcaggaacc ttgccaaaag gcacccacct agccagcact atcactgtgg ctccagcctg
    18841 ctgcctgtgc tctcccttgg ggctcttcca cattgtcggg gggctcagca ggcccaggct
    18901 cctccctgct gaaaaggact aaggctgatg ttacttatgt cctcctcaaa gggcctgccc
    18961 tttcaaacgt ctcttgaaat cacgaggcca tccatttcag acttggaatc ttgggttatg
    19021 tagagaattt gccatcttgg tatttgctat aactggattt gacaatgact ccaatttttc
    19081 aagctcactg tctttctcta agggcagact atggtcggtg cttaattagc cacaaagttc
    19141 acagaactag agacaggaca cacatctgag atgcatgggt gtccaaggag ttctccctcc
    19201 aggaatctcc ttgagaagta gcaggcagaa aatcacattg gggttatgat gagaatgggc
    19261 ctgaggcagg aggatggagt tccattccct ctcataagat acatagggga ccaccaggga
    19321 ctcctgtttg aaatgcaggt tccaaggctc tagctacagt gtttgattca gtagtggggc
    19381 ccaggaatca gcatgttaac acaaactcat ttgtgatgct acagatggct cccaaatcca
    19441 cttttaagaa atatttgtta gggttccttc aaggtaacag tctagaatcc tatcatcccc
    19501 agagttccac tgtggttcag agcagattca gggacatcat acatgatgtt tgttcctgaa
    19561 tcttagagca tcttcccaca gaactctgat aactgagtgc acctgtgatt ccagagaatg
    19621 ggaccagggc ccccttccac accctgtcac agcccatgca tctgtgccgt aatcaggcca
    19681 ataactctga agccctgcag ggatctgggg tctacaagcc accagttcca gtcaccgttc
    19741 ttgggaggaa gaacgggggc aaagcaatgt atggaaacaa atgtttatct agtgcactct
    19801 ctatcaagca gctaatgaag cagacaactt atgatcagcc atgtcattca ccaactggca
    19861 cagttacaga ggggtgccag agcaggtcac cacagtagaa caaaatcaag gtgttcacat
    19921 tttgccttaa gtggcgtttc attgctattg aataca
//

