LOCUS       NG_008461              26300 bp    DNA     linear   PRI 07-MAR-2012
DEFINITION  Homo sapiens Berardinelli-Seip congenital lipodystrophy 2 (seipin)
            (BSCL2), RefSeqGene on chromosome 11.
ACCESSION   NG_008461
VERSION     NG_008461.1  GI:197927417
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 26300)
  AUTHORS   Magre,J., Delepine,M., Khallouf,E., Gedde-Dahl,T. Jr., Van
            Maldergem,L., Sobel,E., Papp,J., Meier,M., Megarbane,A., Bachy,A.,
            Verloes,A., d'Abronzo,F.H., Seemanova,E., Assan,R., Baudic,N.,
            Bourut,C., Czernichow,P., Huet,F., Grigorescu,F., de Kerdanet,M.,
            Lacombe,D., Labrune,P., Lanza,M., Loret,H., Matsuda,F., Navarro,J.,
            Nivelon-Chevalier,A., Polak,M., Robert,J.J., Tric,P.,
            Tubiana-Rufi,N., Vigouroux,C., Weissenbach,J., Savasta,S.,
            Maassen,J.A., Trygstad,O., Bogalho,P., Freitas,P., Medina,J.L.,
            Bonnicci,F., Joffe,B.I., Loyson,G., Panz,V.R., Raal,F.J.,
            O'Rahilly,S., Stephenson,T., Kahn,C.R., Lathrop,M. and Capeau,J.
  CONSRTM   BSCL Working Group
  TITLE     Identification of the gene altered in Berardinelli-Seip congenital
            lipodystrophy on chromosome 11q13
  JOURNAL   Nat. Genet. 28 (4), 365-370 (2001)
   PUBMED   11479539
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Valerie Delague. The reference sequence was
            derived from AP001458.6.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes the multi-pass transmembrane protein
            protein seipin. This protein localizes to the endoplasmic reticulum
            and may be important for lipid droplet morphology. Mutations in
            this gene have been associated with congenital generalized
            lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare
            autosomal recessive disease characterized by a near absence of
            adipose tissue and severe insulin resistance. Alternatively spliced
            transcript variants encoding different isoforms have been found for
            this gene. Naturally occurring read-through transcription occurs
            between this locus and the neighboring locus HNRNPUL2
            (heterogeneous nuclear ribonucleoprotein U-like 2).[provided by
            RefSeq, Mar 2011].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6793              AP001458.6         115049-121841       c
            6794-6794           "G"                1-1
            6795-26300          AP001458.6         95542-115047        c
FEATURES             Location/Qualifiers
     source          1..26300
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13"
     STS             1502..1630
                     /standard_name="D11S2291E"
                     /db_xref="UniSTS:30592"
     STS             3625..3776
                     /standard_name="D11S1084"
                     /db_xref="UniSTS:65274"
     gene            4956..24313
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /note="Berardinelli-Seip congenital lipodystrophy 2
                     (seipin)"
                     /db_xref="GeneID:26580"
                     /db_xref="HGNC:15832"
                     /db_xref="MIM:606158"
     exon            4956..5428
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     gene            complement(5369..6981)
                     /gene="GNG3"
                     /note="guanine nucleotide binding protein (G protein),
                     gamma 3"
                     /db_xref="GeneID:2785"
                     /db_xref="HGNC:4405"
                     /db_xref="MIM:608941"
     mRNA            complement(join(5369..5897,6181..6280,6660..6981))
                     /gene="GNG3"
                     /product="guanine nucleotide binding protein (G protein),
                     gamma 3"
                     /inference="similar to RNA sequence, mRNA (same
                     species):RefSeq:NM_012202.4"
                     /exception="mismatches in transcription"
                     /transcript_id="NM_012202.4"
                     /db_xref="GI:374081837"
                     /db_xref="GeneID:2785"
                     /db_xref="HGNC:4405"
                     /db_xref="MIM:608941"
     STS             5396..5547
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /standard_name="RH12537"
                     /db_xref="UniSTS:39883"
     CDS             complement(join(5769..5897,6181..6279))
                     /gene="GNG3"
                     /note="guanine nucleotide-binding protein gamma-3 subunit;
                     NBP gamma-3"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-3"
                     /protein_id="NP_036334.1"
                     /db_xref="GI:6912394"
                     /db_xref="CCDS:CCDS8032.1"
                     /db_xref="GeneID:2785"
                     /db_xref="HGNC:4405"
                     /db_xref="MIM:608941"
     STS             5772..6264
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /standard_name="Gng3"
                     /db_xref="UniSTS:496686"
     misc_difference 6794
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /note="This sequence differs from the reference genome
                     assembly (NCBI Build 36) at this position. C was replaced
                     by G to represent the standard allele identified by
                     alignment of public cDNAs. The difference is in the
                     adjacent gene GNG3 as a retained mismatch."
                     /replace="c"
     mRNA            join(6868..7466,8958..9274,12026..12107,19864..20007,
                     21778..21912,22102..22199,23154..23295,23434..23500,
                     23708..23788,23883..23963,24054..24313)
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /product="Berardinelli-Seip congenital lipodystrophy 2
                     (seipin), transcript variant 1"
                     /transcript_id="NM_001122955.3"
                     /db_xref="GI:325910876"
                     /db_xref="GeneID:26580"
                     /db_xref="HGNC:15832"
                     /db_xref="MIM:606158"
     exon            6868..7466
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=2a
     exon            7251..7466
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=2b
     CDS             join(7380..7466,8958..9274,12026..12107,19864..20007,
                     21778..21912,22102..22199,23154..23295,23434..23500,
                     23708..23788,23883..23963,24054..24208)
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Bernardinelli-Seip congenital lipodystrophy type 2
                     protein"
                     /codon_start=1
                     /product="seipin isoform 1"
                     /protein_id="NP_001116427.1"
                     /db_xref="GI:171906569"
                     /db_xref="CCDS:CCDS44627.1"
                     /db_xref="GeneID:26580"
                     /db_xref="HGNC:15832"
                     /db_xref="MIM:606158"
     exon            8260..8372
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     exon            8958..9274
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            12026..12107
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     exon            19864..20007
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     exon            21778..21912
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=7
     exon            22102..22199
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=8
     exon            23154..23295
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=9
     exon            23434..23500
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=10
     exon            23702..23788
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=11a
     exon            23708..23788
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=11b
     exon            23883..23963
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=12
     STS             23898..24218
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /standard_name="D11S4928"
                     /db_xref="UniSTS:31824"
     exon            24054..24313
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /inference="alignment:Splign:1.39.8"
                     /number=13
     STS             24108..24248
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /standard_name="RH12527"
                     /db_xref="UniSTS:58367"
     STS             24115..24223
                     /gene="BSCL2"
                     /gene_synonym="GNG3LG; HMN5; SPG17"
                     /standard_name="D11S4063"
                     /db_xref="UniSTS:154160"
     gene            24676..>26300
                     /gene="LRRN4CL"
                     /note="LRRN4 C-terminal like"
                     /db_xref="GeneID:221091"
                     /db_xref="HGNC:33724"
     mRNA            join(24676..25148,26062..>26300)
                     /gene="LRRN4CL"
                     /product="LRRN4 C-terminal like"
                     /inference="similar to RNA sequence, mRNA (same
                     species):RefSeq:NM_203422.2"
                     /exception="annotated by transcript or proteomic data"
                     /transcript_id="NM_203422.2"
                     /db_xref="GI:306966177"
                     /db_xref="GeneID:221091"
                     /db_xref="HGNC:33724"
     CDS             26067..>26300
                     /gene="LRRN4CL"
                     /inference="similar to AA sequence (same
                     species):RefSeq:NP_981967.1"
                     /exception="annotated by transcript or proteomic data"
                     /note="LRRN4 C-terminal-like protein"
                     /codon_start=1
                     /product="LRRN4 C-terminal-like protein precursor"
                     /protein_id="NP_981967.1"
                     /db_xref="GI:44662821"
                     /db_xref="CCDS:CCDS8030.1"
                     /db_xref="GeneID:221091"
                     /db_xref="HGNC:33724"
ORIGIN      
        1 ggggactgtc cttgatggca gagcagaata gcctgcccct tctatagacc cattgattaa
       61 ttcctgtaaa atcttgggga gaatgggatt gcagccctca gcctaaagat tgtgatttgc
      121 cagtctctag tctctgtctt ccaaggttga gagaggtggg aggtctctga aatcatccct
      181 gttagagtgt ctgtcctctt acagtgcgag agaaggaacg tttctcaggg tttcagctca
      241 cacgaaaaca cagcaggatt cttttcactg cagcgggata tgtatatagg tgaatcctgt
      301 ggtgtgggct cacaggccca ggtgctgaga atagcaacta gcaactattt tctacagtgt
      361 ggagggctcg tgccctgctg gtttttttga tacacaggta gagaatgaat agaagagggg
      421 agggtggtgg gggggggtgg gaggcagctc agtggggctg ctgaaccttg ggaagagtgt
      481 gagtgtgaac gtgtgtaaat gtgcgtgtga aagggagcac cccttcccga cttctagaaa
      541 caaaattcct tttggggcgc tttccctgtg tgtccccaga gaggcctcta gccaggagcc
      601 ttcagttggg atagtttcat ttgtgacttt accaataccc tcccagttct tgatagacag
      661 ctgtaggttg ctgggttcaa gaatatgggt gggatatgga atgctctttc aatgtctagc
      721 ttcagttttc attcatcctc ctgctcagca ctgtcagcca agagcttact cagcagacac
      781 cacatactgc agcagttcct agtgagaaaa tctgtgccac tagaaaatgc ttcacttcca
      841 tttcctcacc tgggcagttc tctgtttaaa attgtgggct gatttggtct tcctctcctc
      901 ctcccactgt tactgccctg cagcccttgt tcaggtgtac agacccttat tctggcctct
      961 agtgtccttg tctgtcatga cacacccttc cgcccaaata cctctgaccc caaggctgga
     1021 atggggctgg taggagataa gtttgcttac tcatagtcat gtcctttctc ttggcacctg
     1081 cttccctgcg gtgtcctcaa atggatttct gtgtggcagt ggagtgattg catgaatttt
     1141 tctgtaacac attaactttg tattattatt aagggagttt gagaaagctt tgcttataat
     1201 gtcaaggcaa ggaggtaaaa actggagccc aaagaaattc ccttagggca agattatgtt
     1261 ataatagaaa attgaatttc ctgaggcagt ggctgccacc ccttttcaga tgtttagtcc
     1321 tgcaaatagc atctttcttg tagtctgtga catggatggg gatgctaggg cccttagggg
     1381 caaggggact aaactaaatc aagttgagtt tttttccagc aggggttagg ggaggtactc
     1441 gctgttgata tttgacacta gaaagtaatc ttttttacaa aactgttttt ctaggtgggt
     1501 ggaaagtgaa actgccacat ccttgttggt ttagtccaag agatcatttg caacaacagt
     1561 agatgtccgg gttttgtttc tgtcttttta ttatgaaaaa ctatgttaag ggggaaaatg
     1621 tggattatgg taaccagagg aatccctagc cttgttttcc ttagaagact tgtttagtgt
     1681 tttatcagac gtctgttgta gttgtagaca ggaaagcttg tgagaaaaac accacatgga
     1741 gcctgtaaat gtttttgcac aacctgtaaa gcattcttgg aagtggccag taaaaagggg
     1801 ttttaccatt taaaaaaaaa atgtaactgt gtcattgttt acatctgtaa ctttttcctc
     1861 ccctgttctc attacaccat tctggcgaaa atgtaggcaa agtagcttcc agttttagaa
     1921 taaataacca tttggattga attcacccta tctcctgtgg ctgcactgac tggggcggag
     1981 ggtgtcactg ggttatttat tcatttttta atgcctcttt ctcaggtcgc atgggctcca
     2041 accaaggagg actctcctct tgcatggtgg ctgccgttcc ctccctattc taccatgcct
     2101 tcacttggga gccagccatg cagtcagttg acatgggtgg gtagttatta gtctatttag
     2161 tgcttgctta ggccaagagt cgagccattg aagtatagga aaataaatta taactcacga
     2221 cctctgtatt tggcctatgc aaaaactagt tggatgcttg aagttaaatg tacattgtgg
     2281 agccaaataa gtatattcat gaataattac tgctaggggg aaagcccact cattcaacag
     2341 aagtttgatg ggggttattt tccagtgaat ctggagaacg agacggtaaa ttaaatttac
     2401 aacagcgcca ttgctttttt attttttatt tttattttta tttttttttt ttgacagagc
     2461 ctcgctctgt tacccaggct ggagtgcagt ggcacgctct cggctcactg caacttccgc
     2521 ctcctgggtt cgagcgattt ttctgcttca gcctcccgag tagctgggac tacacatgtg
     2581 tgccaccagg cccagctaat tttttttttt tttttttcct agtagagaca gggtttcacc
     2641 atattggcca ggctggtctt gaactcctga cctcgtgatc tgcctgcctc agcctcccaa
     2701 agtgctggga ttacaggtgt gagcctccgc tcccagccac cattgcatta ttagcactga
     2761 aatgatccta acggcagttt ctaataaatg gtcagggtct taaagctgag ataccacagg
     2821 ctcatgacat ccagtgttct gaaggagtag tagtattgat gtagatactg ctctaattcc
     2881 taccctctgt atgtgacacg gattcagata cccgggttta cagttttgta ccctgaaggc
     2941 cacccttaat tttggtagcc atctattctt taggacattt aagttgctgt tagagctaat
     3001 taatcatttt ttaaagtggt taatcatagc tcatgcctgg tctctagtta ctgcttaaac
     3061 cccattttcc cacctagcgc tgtagccacg cagttataat ctgatgggta ggaacattga
     3121 gtgtgcagaa aaattgaaga gaggcgcttt gttttgtttc gttttgtttt gagacggagt
     3181 ttcgctcttg ttgcccaggc tggagtgcag tggcacaatc tcggctcacc gcaacctctg
     3241 cctcccgggt tcaagtgatt ctcctacctc agcctcccaa gtagctggga ttacaggtac
     3301 ccgccaccac accggctaat ttttgtattt ttagtagaga cagttttcac cgggttggcc
     3361 aggctggtct cgaactcctg acctcagatg atccgcccgc ctcggcctcc caaagtgctg
     3421 ggattacagg catgagccac cacgcccggc cggccaaaaa gaggctttct taaaaatcaa
     3481 ggttacattt attaaacact ctaatttttt ttttttttat ttaaccatgt ctgagctgtt
     3541 gtggaaaatt tcacttactc ccctggaact tgcccaacac cgtgatacag tgggggtgag
     3601 ggaggcaagg tgcttggtcc ctgccatgcc acatttgcca tttaagcatg tacagtacaa
     3661 tctattcatt gggtatttgg gtgcctgata tgtgccatta tcaggataca gggattaaaa
     3721 cggacctgac ctgattgatc cttcctggaa ttttcaccgt gccaagaagg aactgaggct
     3781 cctccgcaac agaatggggg tagggtccca ctccaggagg gcaaacttct cccgtttctt
     3841 catctctagg atgagggaat taattagaag atctccagga cttcttagag ctcagaagtt
     3901 ccatcaacag taaaaagttg cttgggacac cttaaggtga cccaagttca ctgggtgtcc
     3961 ctggaattca tgaagatatc cttaggaggc taagttcagt tgctggtgat aacaaccttt
     4021 cttcctttgg tttcctttat ccactttgct gtcttctgtg caaagatacc tggaagctgg
     4081 aggtaatgag ctgtccctac tatttcaaag cagcctccct tcccgaagta tatccaggca
     4141 caaaacagga gccagcctag gcttttcctg gggaggatgc gtccctgagt ttaggggacc
     4201 tctagcagga gcacacgtac tgggattgtt acgttctttg tcttgtccct ggtcccatct
     4261 cgcctctgtg cacccttgga aggaaaagat tctaggaggc attctggtgt tcgtaaacct
     4321 ccgccatgtt tgagtcctgg agatgaccat gacatgttaa gccttaagtt tggtccctgc
     4381 ccagacagca tgctggactt ttgcaaggca cattaggggt gcggccactg ctttctggct
     4441 gctgtggctg aatcggcctg aggggaaaat gaaagcaaaa acaagcccca gttctactag
     4501 gaaacccaaa ctgagcaact tcaggcttat ccagctcctg ggaagaccag gaagcaactg
     4561 aggagcggtg caccgagacg gacagggtcg ggggttaacc ccctgccgct aatatttccg
     4621 ctccaaaggg agcctctcct ttcttggcaa aatgtagaaa cctagattcc ctcgcaagat
     4681 ccacgcgacc agcgtcggcc acgctgtact tcctggggtc cccttgttta gtgattcttc
     4741 gttatggccg cccgtgtgcc ttcgactcaa tcgggaggac accgaaatcc agatttcggg
     4801 gttgcagggc gcgggccccg gcttggttag ggcaggggca gccattttga gaccagaaga
     4861 gggcggaagg gaccatattg agaacgccgg ttgcctgggg gccgccattt taagagaagc
     4921 cctgtacggt aaactccgtg acgtgggggc tgccatgttg gtacggccat cttggaatgg
     4981 gagtggctgt gggcgcagcc atcttaggta taaaatcggc tccagtcgcg gtaactgaag
     5041 ccaagctccg cccctaccct cctaagagtt cctctgctgt acgactgcac tcccgcaccc
     5101 tcccctaaat cccccctctt cggcctgttt accttttaac ttggcttcgt tgcacgtttg
     5161 tgtgtgtgtg tttgctcttc gcagcctctt gagcgtcttt tgtacttaat tcttacactg
     5221 tggacgctct ctcgcgcccg ccatcccccg acccctctga tctccgatcc ttgacgatgt
     5281 ctagcctgca ttgattggcc cttttccctg ggtatggcag atctattgct tgatgatcct
     5341 ctccccccaa gaattctaac acaggagctg tcctgaggct ctggatgact ttattcttca
     5401 aatggcttta ccctcccagt agctccaggt gagactgaga gcaagaacct ggcccatccc
     5461 tctccattgt ctgagcaggt caccgaggga agcgggcagg acgcgctggc agagtctgac
     5521 ggggccctgc tgtgggtgga gcaaagggtg cctcatatct ctggggtgct tggggtcggc
     5581 cacaaaggtg gtaggaaatg gggtcgacag ataggtgagg gtgggccttg tgcttcagat
     5641 aacctcacat ggtcaggcaa gggttaggga tgggatgcaa ggagcctaag gggctcacaa
     5701 caattactga cctaaggaag ggcccaggag agggaaaagg gaggagttgt gagaagggac
     5761 aggggagctc agaggagagc acagaagaac ttcttctccc ggaaggggtt ctccgaagtg
     5821 ggcacagggg tgatgagggg atcctcacag gcgtgggcat cacagtaagt catcaggtct
     5881 gctgctgcct tggacacctg ggacacagcc aggaagggta ttgttagcca ggacctctga
     5941 aggggactgc agcctccctc cccaaatggg ttctcttttg ccatctccag ggctccttac
     6001 gacttgtctt ctccctcatc ccccccagag gcctggggac agctctctct acagagcccc
     6061 agactcctcc cctgacctca gggagtgaag gaaagaacgc atctcttatc ttgagctttg
     6121 ggaacctgca gcacagcaca gcctggccaa ctaatgggag ccagccaggg tcccacctac
     6181 ctttatccga cacaagctgg cttcaatctt aagctgttcc accatcttgc gtgcttgccc
     6241 aatactcata gtgctgttca ccggggtctc acctttcatc ctggaaaaaa gagggacctc
     6301 tcagagcaca gtctcagctg gaggcccccc tccatgctca ctccacacca acctttacaa
     6361 ggctgtggtc ataccccaat attttgttcc cctcctatcc tcctcctcct cctccagtgg
     6421 actgtctcat ccctgtattc ctcatggaaa aaaatagggt gggatgaggt gctccccaaa
     6481 ctccctcatg gcctgggcca cagatcatta aaccttacac aaatgattta aggcttttca
     6541 gcccttcaaa ccatgtgtgt tcccagctct gaagacctca accaaccctg atgaggaggg
     6601 cacatcaccc ctgtctgctc cagtgagccc caacaggaga aaaacaggcc attacttacc
     6661 tgaagccaca agcggcagta gcagccctgg gtgtagggtc agtggagggt accaaaacct
     6721 tctgcctgaa atgggtgccc cacccagtag ggagttgcag ctgaaagtat ctgatgcaga
     6781 agcagtgact ataggaaagg aggcccctgg ggagggccag gccagaggtc tggtctcagt
     6841 ttctgcagct caagcactgt ctggatggct ggtacctgaa ggatgaagga tgctagaagg
     6901 agctgctcag atcctggagc ataccaactg cctggccagt gggggagcct agctgcctgc
     6961 atccctgcgc acacccccac tgtcgctagt tcactgcctg cccctccccc attgcaggca
     7021 tcctgactct gggctagaga cctccccaac agagctgagg ccaaggccga ctccccctct
     7081 caaatggcgt ggtctgggcc tatgacggcc cctgcagtgg agtctgtact ggctgcgggg
     7141 gaccctgctc atttgaaaat ctgacatcag ctgggcagtc gcccccctcc tcctttcctc
     7201 cctctactct gacacagcac ttagcacctg aatcttcgtt tctctcccag ggaccctcca
     7261 ttttccatat ccaggaaaat gtgatgcgcc acaggtatca gcgtctggat cgccacttca
     7321 cgttttagcc acaagtgact cagtggaaga tccagagtca acagaggctc gtcaggaaga
     7381 tgtctacaga aaaggtagac caaaaggagg aagctgggga aaaagaggtg tgcggagacc
     7441 agatcaaagg accggacaaa gaggaggtag gggcccttgt ggggacagtc agcagaaata
     7501 tactggaaat aggtgggctg gcgtgaaggg ggcgggggga tggattggtt ttaagaattt
     7561 cattcatttt gaatagatta cttcccacgc ccgcagcagt gtgcaaagat gtacacaaca
     7621 ctggccttgc ctctgaagga ctttatctgg ggtgattaga cgtctacaaa atagaagact
     7681 gccaaaagct agtctagata atgtgctgtg gggactctga gggagagtgt atccagttag
     7741 ggtcagagga ggtccacaat gctaccacgc tgggaacagg gcactaatct gcctgcgcaa
     7801 caacgcaaga ggcccaggtt gccgcaaact gcaacatgct ctaggcgaat gcccccgcct
     7861 tagatgccta caggtcctag gagctgtggg cgataaaaat cagcgccagc tggatgaccg
     7921 cctcactcgg ccgcttcgcg ggtgaaatgg cctgtggtga aggtgtgcac ggagggctgt
     7981 gattgcagtc tcaagggaga gccgagcgga ggctgcagtc agcgcatccc ctggggcaca
     8041 tcttggggcc tgcagggagg caggcgtctt tcccctttgg tcacggtaac cggagggaaa
     8101 cctgccgcag agagagccag tggcgagcgc aaggagacag cgacctcgca gctcgggaag
     8161 gctccgcccc gtcccgcccc gccccgccgt gctggacccc gccctgggct gaagccccgc
     8221 ctcccacggc tacaaaagcg gccggcggag aggggcggga cttccccggg agccggaagt
     8281 cccgtctcac ggttgccctg gcagcgcgcg aggctggtga gtcggcagcc ctgtggcagc
     8341 cggcgggctg gtttccatgg ttgcacgatt aggtaggggc tccgggcgct ttgcccaccc
     8401 ccgagctgga ggggactggc gggaagcggc ggttggctgc agggcgctcc gccgggcgtg
     8461 gggtgtagcc gtgtcggtga gcgagctctg ctcgaggcgg agaggagaaa ctcgggaagc
     8521 aattgtggct actctaaggc tactggtttc gagtcaggcc gtgcgacctt aggcaagtcg
     8581 cacattctct ccgtgcagct gcctagcagt gtggattcag tatcaccgtg tgtgtaaagc
     8641 tctttctaag aatcgtaagg tgcttattct ttgttatata gctgtgaatg agaatcaagg
     8701 tggtttgtcc cagcatcaaa tgactggaga aggaattcca ctgaggagat ttagcactgg
     8761 gcgggaggga acacagtgga ggaaagggaa ggggtaattg gcagagtggc acaatcattt
     8821 ggagaaaggc catatatatg aaacaatgac tttgctatcc tgctatctct cgttcctcaa
     8881 agccagtcca gtaagctgtt ttgtccccac ctccctgggg aaaggagtca ctcttttccc
     8941 tcaccctctc tttccaggaa ccaccagctg ctgcatccca tggccagggg tggcgtccag
     9001 gtggcagagc agctaggaac gcaaggcctg aacctggggc cagacaccct gctctcccgg
     9061 ccatggtcaa cgaccctcca gtacctgcct tactgtgggc ccaggaggtg ggccaagtct
     9121 tggcaggccg tgcccgcagg ctgctgctgc agtttggggt gctcttctgc accatcctcc
     9181 ttttgctctg ggtgtctgtc ttcctctatg gctccttcta ctattcctat atgccgacag
     9241 tcagccacct cagccctgtg catttctact acaggtgaga ggggccttct atcaaaatag
     9301 aggactccta tgggaattgt aaggcccttg gagttcattc agttcaatcc cctcatttac
     9361 agataaggaa aactggagcc aggtgtgctt ccagggcctc tcaactttca cagcccaagg
     9421 ctagatttgg gttgccaggg ctagggttct agttctacct ctgattactg aattctggtt
     9481 aaaaaaaaaa aaaaaaaaag gaaaaatatc cacttctatc attatgagga tcaattctat
     9541 tttggttgga tcacccctct ctcagggcca atgtagaatt ttgagccaac tcaacccttt
     9601 agtgcagaac caacctggct ttcagtagag gagctattag gaaagcagca gtttgctttt
     9661 tacattactg cctctcagtc cctgaaagtc ggctacacaa tagagattat ggaaacataa
     9721 gatgagtagg cgcataaact tgcttcccag agagtcttgc gtcttgactg gccccttagg
     9781 ttccttctca ttttacaaac cctgccaagt gccaaattct ctcttttttg aggtggagtc
     9841 tctctctgtt gcccaggctg gagtgcagtg gtgcagtgtc tgctcactgc aacctcccag
     9901 gttcaagcaa ttctcgtgcc tcagcctccc aagtagctgg gattacaggt gtgtgccacc
     9961 acatctggct aatttttgta tttttagtag agatgggttt ttttttgttt tgttattgtt
    10021 tttgtttttg agatggagtc ttgctctgtc gcccaggctg gagtgcagtg gtgccatgtc
    10081 ggctcactgc aagctccgcc tcctgggctc acgccattct cctgcctcag cctcctgagt
    10141 agctggtact acaggcacct gccaccatac ccagctaatt tttttttttt tttttttttt
    10201 tttttagtag agatggggtt tcaccttgtt agccaggatg gtctcaatct cctgaccttg
    10261 tgatccacct gccttggcct cccaaagtgc tggggagatg gggtttcacc atgttggcta
    10321 ggctggtctt gaactcctga atgcaggtga tccatccgcc ttggcctccc aaagtgctgg
    10381 gattacagac gtgagccact gtgccccacc aaggtctctt cttcttcttc tttttttttt
    10441 ttttcttttt gagacagagt ctcgtgctgt tgcctgggct ggagtgcagt ggcgcaatct
    10501 cagctcactg caacctctgc ctccagattc aagccattct cctgccttgc ctcagcctcc
    10561 caagtaactg ggattacagg tgcctgccac cacacctggc taattttttt ttgtattttt
    10621 agtagagatg gggtttcact atgttggcca ggctgatctc gaactcctga cctcgtgatc
    10681 cacccccttg gcctcccaaa gtgctgggat tacaagcatg agccactgcg cccggcctag
    10741 ttctcttttc ttaacagtgg ttgtaggacc tatcaacaga tgcagagaag ggcgttataa
    10801 tcaatggttt aaagtcattt tttcccttaa gtccctggtc cagagctata gtttctaaag
    10861 cagagcttct taaactttta ggaaatggat cttatggccc ttcctgccat aaaaacatat
    10921 atacggccgg gcgcggtggc tcacacctgt aatcccagca ctttgggagg ccgaggcagg
    10981 cggatcacaa ggtcaggaga ttgagactat cctggctaac accgtgaaac cctgtctcta
    11041 ctaaaaataa aaaaattagc cgggcgtggt ggcaggcgcc tgttgtccca gctacttgag
    11101 aggctgaggc aggagaaatg gcgtgaacct gggaagcgga gcttgcagtg agccgagatc
    11161 gtgccactgc actccagcct gggcgacaga gcaagactcc gtctcaaaaa aaaaaaaaaa
    11221 aaaaaaacgt atatgcatgc ccaggcatat gctgcaccca cacccccaca tgcaaatttg
    11281 cctacaattg gaggggttca tgagcttctt aataaccatc tgtagatcct tttggaggcg
    11341 ttttctcaaa ctaggaccca gaccagagct accaaatcag aatctcttgg ggtgggaccc
    11401 tggaatttcc tttttttttt ttttgagatg gagtttcacc cttgttgccc aggctggagt
    11461 gcagtggcgt gatcttggct caccacaacc tctgcctccc aggttcaggc gattcttctg
    11521 cctcagcgtc ccgagtaggt gggattacag gcatgcgcca ccacgccccg ctaattttgt
    11581 atttttagta gagatggggt gtctccatgt tggtcaggct ggtcttaaac tcctgacctc
    11641 aggtgatccg ccctcctcgg cctccaaaag tgctgggatt acaggcgtga gccgctgctg
    11701 cttggccctg gaatttacat ttttatcaag ctccttaagt ctttagaaac actgaagtat
    11761 gcaactattt aagtatctct agattcccat ctaagaacat ctgttgtaat gagaggacat
    11821 acattgaagt cataggaaga gaatgaaata atcctggtat cttgaatctc ctggccacat
    11881 ttgttctcca tctttgtaac agagagaagg gtgcctgttc tgagagaagg gaggagggca
    11941 ggagggagcc ctagggggca aagaaggtgt atggatggac tagtaagact aacttagcag
    12001 agtatcctcc tccaatctca tttaggaccg actgtgattc ctccaccacc tcactctgct
    12061 ccttccctgt tgccaatgtc tcgctgacta agggtggacg tgatcgggtg agtatgggaa
    12121 ctagagagag gtttcattag agctttgatg actcaaaata ggaagacttg agaaaggcct
    12181 agagagaagg aattgagtaa taagagactg gccgggcacg gtggctcacg cctgtaatcc
    12241 cagtactttg ggaggctgag gtgggcagat cacctgaggt tgggagttcg agaccagcct
    12301 gaccaacgcg gagaaacccc gtctctacta aaaatacaaa attagctggg cgtggtggtg
    12361 catgcctgta atcccagcta cttgggaggc tgaggcagga gaatcacttg aatccgggag
    12421 gaggaggttt cggtgagccg agatcacgcc attgcactcc agcctgggca acaagaatga
    12481 agctctgtct taaaaaaaaa aaggagacta agaggaaggc tttgaaggaa aagaaattaa
    12541 aattaattgt gtgtattgat ggatctttct gcagcaggtg ttagaaatgt tctttctcaa
    12601 catagtccct gacttacggt aattcaactt aagaattttt caacttactg tggtgcaaaa
    12661 gcgacataca ttccttagac actgtacttc aggtacctat acaaccattc tgtttttcac
    12721 tctctttctt tttttttttt tttttccaga cagtctcact ctgtcgccag gctggattgc
    12781 agtggcgcga tctcagctca ctgcaacctc cacctcctgg gttcaagcga ttctcctgcc
    12841 tcagcctccc gagtagctgg cactacagga gcgcgccacc acacccagct aatttttttg
    12901 tatttttagt agggatggga tttcaccatg ttggccagga tggtctggat ctcttgacct
    12961 tgtgatctgc ccgcctccca aagtgctggg attataggcg tcagccacca cgcccagcct
    13021 gtttttcacg ttcagtacag cattcaataa atcacatggg atattcacta ctttattata
    13081 agtataggct ttgtgttaga tgattgtaat caactatagg taggctaaca taagtgttct
    13141 gagcatgttt aaggtaggct aggctaagta agctatgatg ttctttaggt taggtgtact
    13201 aaatgcgttt tcagcttgtg atagtttcaa cttagatggg tttatcggaa tgtaacccca
    13261 tcataaactg aggaccatct gtatcaggtg aagtatgatc tatttatctg ctaggtaaag
    13321 tgagcaatat ctgctaggtg aagtaagcaa tgttttagac ctaaatgaac aaatgagcta
    13381 ttacattgga ataagatggg catctaccca agagttttga aagcatttat ataacattat
    13441 gaaactgttg tcaaatatat gcatcgtgtc attacaaagg gtactgtgcc agaggactgg
    13501 ccagatgcca gtgtgatgtc aacaaacctg ggaaccctga gaaatgcata tggggactgg
    13561 gccctctata gtaggcaagc tagaggaggc tctcataaag gatacgttct tttttttttt
    13621 ttgagacaga gtcttgctct gtcgccaaga ctggagtgca gtggcgcgat ctcacttcac
    13681 tgcaacctcc aactcctggg atcaagcgat tctcccacct cagcctcctg agtacctggg
    13741 attacaggtg cccaccacca cacccggcta acttttgtat ttttagcaga gacagggttt
    13801 caccatgttg gtcatgctgg tctaaaactc ctgacctcag gtgatccacc cacctcggcc
    13861 tccaaaagtg ctgggattac atgcgtgagc aaccacaccc agcctgaagt tttatttatt
    13921 tatttattta tttgagacgg agtttctttc ctgtcgccca ggctacagtg caatggcacg
    13981 atcttggctc gctgcaacct ctgccccctg ggttcaatcg attctcctgc ctcagcctcc
    14041 caagtagctg gggttacagg cgtatgccac catacctagc tgatttttgt atttttaata
    14101 gagacggggt ttgatcatgt tggccaggct ggtcttaaac tcatgatctc aggtgatctg
    14161 cccacctcag cctcttgaag tgctgggatt acagacatga gccaccatgt ccagcctgaa
    14221 gttatttttc aaaagtggta ctttggagga aactgatgta atgatagaat gtcacacttt
    14281 tgaagggagg agtataacct atagagtctg gggttctatt ttattttatt tttcaagaca
    14341 aggttttgcc ctgccaccta gcctggagtg cagtgatacg atcacggctc gctgcagcct
    14401 tgacctccca ggttcaagtg atctcccaag tagctgggac tacaggtgtg tgccaccatg
    14461 cccagctttt tttttttttt tttttttttt aatttttagt agagacaaga tcttactatg
    14521 ttgcctaggc ttgtctcaaa ctactaggct caagtggtcc tcccgactca gcctcccaca
    14581 gtgttaggat tataaccggg tgtggtggct cacgcctgta atctcagcac tttgggaggc
    14641 tgaggaggca ggtgggtcac ctgaggtcag gagttcgtga ccagcctggc caacacagtc
    14701 gaaccccgtc tctactaaaa atacaaaaat tagccaggtg tggtggcaca aacctatagt
    14761 cccagctact ttggaggctg aggcacaaga attgcttgaa cccgggaggt ggaggttgca
    14821 atgagccgag actgctccat tgcactccag cctgagtgac agagcgagac tcagtctcaa
    14881 aaaaaaaaaa aaaaaaaaac cagataggat tttgctatgt tgcccaggct ggtctcaaac
    14941 tcctgggctc aggcagtcct cccacctggt ccttccaaac tgctgggatt acaggtatga
    15001 gccaccatgc ctggcctaga atcttctata aagacattta ttcagtttgc ttctatggtt
    15061 aaaaaataat aaatgacttg actgggcaca gtggctcacg cctgtaatcc cagcaatttg
    15121 ggaggccgag gcaggcggat cacatggtca ggagtttgag atcatcctga ccaacatggt
    15181 gaaaccccgt ctctactaaa aatacaaaaa ttagccaggt gtggtggcgc aggcctgtag
    15241 tcccagctac ttgggaggct gaggcaggag aaaggtgtga acctgggagg cggagcttgc
    15301 agtgagccga gatcgcgcca ctgcactcca gcctgggcta cagagcaaga ctccatctca
    15361 gaaaaaatta ggggccaagc gtggtggctc acgcctgtaa tcccaatact ttgggaggcc
    15421 gaggcgggcg gatcatgagg tcaagagatc gagaccatcc tggccaactg gtgaaacccc
    15481 gtctctacta aaaatacaaa aattagctgg gcgtggtggt gtgcacctgt aatcccagct
    15541 actctggagg ctgaggcagg agaatcactt gaacccagga ggcggaggtt gcagtgagct
    15601 gagatcgtgc cactgcactc cagcctggcg acagagcaag actccatctc aaaataaata
    15661 aataaataat aataataaat gactttattg agaagaaatg agaaagccac agaacctggg
    15721 atggtgcata cagttttgtg gcccattgca gagatcataa tgggaaggca gagagccaag
    15781 ggagggagcc tcaaacgatc aggtgtgagg ctgtcacatg agggagggag gaataaaagg
    15841 aagatgagag caaattcagc ccatgtccct gataattaga agaggttgaa cattttgttt
    15901 gttgacaatg aacattttta aatgaattaa tgaatgaaat aatctgtcca ctatgtgtaa
    15961 cggcttgcta taagtagatg tggtcgctgc tctcaatgag ctcacagcgt tgatggaaaa
    16021 ctatacattg catatgtttg catacattta agtagtaaac tgtaaaatgc ggattctggc
    16081 caggcatagt ggctcatgcc tgtaatccca gcactttggg aggccgaggc gggtggatca
    16141 cctgaggtca gggttcaaga ccagcctgac caatatggtg aaaccctgtc tctactcaaa
    16201 atgcaaaaat tagccaggcg tggtggtgtg tgcctgtagt cccagctact tgggaggctg
    16261 agacaggaga atcgcttgaa cccaggaggc agaggtcaca gtgagccgac atcatgccac
    16321 tgtactccag cctgggcgac agagtaagac tccatctcaa aaagaagagg ccgggcacgg
    16381 tggctcacgc ctgtaatccc agcactttgg gaggccgagg cgggtggatc acggggtcag
    16441 gagatggaga ccatcctggc taaaacggtg aaaccctgtc tctactaaaa atacaaaaaa
    16501 ttaggtgggc gtggtggcgg gcgcctgtag tcctagctac tcgggagact gaggcaggag
    16561 aatggcgtga acccgggagg cagagcttac agtgagccga gattgcgcca ctgcactcca
    16621 gcctgggcga cagagcgaga ctccgtctca aaaaaaaaaa aaaaaggatg tggattctgc
    16681 attccagaag cattcgtgaa gaattagatc agtgttgtct gggatagtct aagaccatgg
    16741 agatggtgat gttcaaagcg gatccttttt tttttttttt tgatacagag tctctctctg
    16801 ttgcccaggc tggagtgcac tggtgtgatc ttgcttcact gcaacctctg cctcctggct
    16861 tcaagtgatt ctcttgcctc agcctcctga gtagctgaga ttacaggcgc atgccaccat
    16921 gtccagctaa tttttgtatt tttttttttt tagtagagac ggggtttcac cacgttgacc
    16981 aggctggtct ggaactcctg tcctggtgat ctacctgcct tggcctccca aagtgctggg
    17041 attacaggca tgagccactg tgccgggccc aaagcggatc ttttaaggaa gggtgaatat
    17101 tacatgggaa tgttagagaa gggggagaat ctgcccatca agcaggcaat tgtggacaaa
    17161 ggcatggaat tttttttttt tttttttttt gagacggagt tgcccaggct ggagtgcagt
    17221 gacatgatct cggctcactg caagctccgc ctcccgggtt cacgccattc tcctgcctca
    17281 gcctcccaag tagctgggac tacaggcgcc caccaccatg cccggctaat ttttttgtat
    17341 tttcagtaga gacagggttt caccgtgtta gccaggatgg tctcgatctc ctgacctcgt
    17401 cttctgcccg ccttggcctc ccaaagtgct gggattacag gcatgagcca ccgcgcccgg
    17461 ccggcatgga tttattcaca aggttttagt attaaattct gtggatccct ttggaggaga
    17521 ttaatttttt tttttttgaa ttggggtctc attctgtcac cccggttgga gtgcagtggc
    17581 ccaatcatag ctcattgtag cctcaaactc ctgggctcaa gggatcctcc tgcctcagtc
    17641 tcctcagcag ctgggactgc aggcatgcac caccacacct ggctaagaga actacctatt
    17701 ttaatgtttc aaagaatttg ggccaagggc agtggctcac acctataatc ccagcacttt
    17761 gggaggccaa ggcaggattg cttgagtcca gcagttcaag accagcttgg gcagcataat
    17821 gagaccccgt ctctacaaaa aaataaaaaa ttagctgggt gtggtggcac atgcctgtag
    17881 ttccagctac tcaggaggct gagacaggaa gatcaactga gcccaggagg ttgaggctgc
    17941 cagtgagctg tgatcacacc actgcactcc agcctttgtg acaagagcga gatcctgtct
    18001 caaaaaagaa aagaattaat agactggggg agtggttgag gggaagaatt cataggctga
    18061 gcaacaaagc aagacccctg tctctccaaa aaaaaaaaaa aatttttagt tgcatgtggt
    18121 tgcatgtgcc tatagtccgt atggtcccag gtacttagga ggcagaggca ggaggataga
    18181 ttgagcccag aagttccagg cacagtgagc catgatcatg ccactgcctt ccagcctgtg
    18241 acagagcaag accttgtctt cacacacaca cacacacaca cacacacaca cacacaaaaa
    18301 gtttatgaag caactggctt aatcatctgg tctctacagg ggggtaggaa tctcatggaa
    18361 tccattttct tcaacagata gttttttgtt tgtttgtttg ttttgagaca gaatcttgct
    18421 ctgtcaccca ggctggagta cagtggcacg atctcagctc actgcaacct ccgcctctcg
    18481 ggttcaagca gctctctgcc tcagcctccg agtagctggg attacaggtg cctgctacca
    18541 cgcccggcta atttttgtat ttttagtaga gacagagttt caccatcttg gccaggctgg
    18601 tcttgaactc ctgaccttgt gatacactcg tctcagcctc ccaaagtgct gggattacag
    18661 gcatgagcca accgcgcccg gccaacagat agttctgact ggcaataaga aggtacaaaa
    18721 aaaggcccct atcagtggtg tcaaccattg ccttagtgat aaacactgaa agcaccccca
    18781 aggctgaacc catgttttgg aggtagttca ctatgggcta gggaagtatt ttccaaattt
    18841 tttttttttt tttttttttt tttgagacag agttttgctc ttgtcgccca ggctgcagtg
    18901 caatggcgcg ctctcggctc actgcaatct ccgcctccag ggttcaagcg attctcctgc
    18961 ctcagcctcc tgagtggctg agattacagg cgcctgccac cacgtccatc taatttttgt
    19021 atttttaata gagacggggg gtttcaccat gttggccagg ctggtctcga actcctgacc
    19081 tcaggtgatc cacctgcctt ggcctcccaa agtgctggga ttacaggcat gactcactgc
    19141 acctggctaa cctttttttt tttttttaac ccattacctc taattaaaaa cagaagcttt
    19201 accctcactc ctgtaatttt tatatactac tgtgtgaggg ccttgttgcc agatatgaat
    19261 caataaaggg gctagaagaa tatagaaata ggaaaaacta gggcatgttt ggtggcaaat
    19321 ctttaacctc ttgagggtga tccctgtgaa gaagccttcc tactctgagt cttggggcgc
    19381 taccaacaga accaagataa gggagctaga atggcagaaa gatgatctgg agcgaggatg
    19441 actgtgccag agctggctgg ggagactgag cactgtcagt gcttgattaa taatgtaaga
    19501 gaggacaggc tgggccctgg ggacagcctc accggcccat aggccagagt cacagatggc
    19561 ccagttggca acatgatggt tcacttttgg aaaagaaacg tgacacagcc tttctgggaa
    19621 cagggtagcc agtctgattc aggagagcca acaggatacc caagaactgg acgtgagagg
    19681 ctctagccac cagaaggggg cagcaccttc ttgggatgac agattgaaag gcccgttagg
    19741 ctacccaaga gggttgtggc tgagtatttg ggggcgttgc gggggctaag agggaggtgg
    19801 aatagagaca gtacattttc aacaaaaaaa tttttttaaa gaaatggggg ctacctttgg
    19861 caggtgctga tgtatggaca gccgtatcgt gttaccttag agcttgagct gccagagtcc
    19921 cctgtgaatc aagatttggg catgttcttg gtcaccattt cctgctacac cagaggtggc
    19981 cgaatcatct ccacttcttc gcgttcggta agtgttggtg gcctgtctga gaaggtgtgg
    20041 aggaagatgg caggatcaga atgggtaggg ggctgggtgt ggtggctcag gcctataatc
    20101 ccagcagttt gggaggccga ggcaggcaga tcgcttgagc ccaggagttc aagactggcc
    20161 tgggcaacat ggcgaaaccc atctctacaa aaaaagttta aaaattagct gggcatggtg
    20221 gctcacggct gtagtcccag ctactctaga ggctgaggtg ggaggatcgc ttaaacctgg
    20281 gaggttgagt ctgcagtgag ccaagattgc accactattc tccctcctgg gcaacagagc
    20341 aagaccgtct caaaaaaaaa aaaaaaaaaa aaaaaaaaag aatgtctggg tagggattcc
    20401 tcaggagaaa acacccttgg ctttgaggtc acagacacat caggataaag aagggaatca
    20461 aggccgggcg cagtggctca tgcctgtaat cccaacactc tgggaggccg aggcgggtag
    20521 atcacctgag gtccagagtt cgagaccagc ctgaccaaca tggagaaatc ccgtctctac
    20581 taaaaataca aaattagctg ggcatggtgg tgcatgcttg taatcccagc tactcaggaa
    20641 gctgaggcag gagaattgct tgaacccggg aggcagaggt tgtggtgagc caagatcgcg
    20701 ccactgcatt ccagcctggg caacaagagc aaaactttgt cttaaaaaaa aaaagagaaa
    20761 ggaatcagct tacaaaacca gaaacctttg ccaaacaccc caggtatctc aggagcatgc
    20821 ccagctttgg gattaagtgt gaagagtgga gctgctctca gaaaacaggc tttagagcca
    20881 gacagacatg ggcttgtgtc ctcattcaga aacaagctag ctgtgggtca cctgacttaa
    20941 cttcttgggt ataaagtatt ataaaatggg tataatagta actgcctcat agcaagacta
    21001 gtttggattc aatggggaaa tgtaaaattc ccattagcac atagtggctg tttaatgttt
    21061 ttttgttttt gagacagaga tcttgctctg tcgcccaggc tggagtgcag tggcgtgatc
    21121 tcggctcacg gcaaccttca cctcctgggt tcaagcgatt ctcctgcctc agcctctcaa
    21181 gtagctggga ctacaggtgc tcaccactac acctggctaa tttttgtatt tttagtggag
    21241 gtggggtttc accatgttga ccaggctggt ctcgaactcc tgatctcaaa tgattcaacc
    21301 acctcagcct cccaaagtgc tgcaagtaca ggtgtgagcc accgcacctg gcctaataaa
    21361 tgttaagact ccattcttcc attaattaac aacacaacct catcatgaag caaattcctg
    21421 atgtctacat gatgggggga aagcttcaga tggtgcgctg ggacttagat cccatactgg
    21481 attacagaac tacttggtgg gaaaggcaga tcagagacag tgctgggctt aatctaggaa
    21541 ggtttcttgg aaggaggggc ctttgctcta taatagagtg tggttgagta gggagagagg
    21601 tactcaagca attggaatgg ttggatgaga ctgaggggta ggaagtgaag gtgaggcagc
    21661 cagggacctg aggaagaagc cgccttcata gactactcag gggtggttga ggggtaggta
    21721 gggtcatggg gatctggcat gcacctgtcc ccagcctctg cttcccaccc ccggcaggtg
    21781 atgctgcatt accgctcaga cctgctccag atgctggaca cactggtctt ctctagcctc
    21841 ctgctatttg gctttgcaga gcagaagcag ctgctggagg tggaactcta cgcagactat
    21901 agagagaact cggtgagtga ggtgaacgag ctttatgact aggagatagc ccctcccatt
    21961 agcccaggat tctacctgag aagcctccag gctcaggaga catcacaact gagagactgg
    22021 aagtggggct cagatgaggc gggtaagagt gctagcggca ggaccctggc ctgacgccac
    22081 cctcacccca ccccctcaca gtacgtgccg accactggag cgatcattga gatccacagc
    22141 aagcgcatcc agctgtatgg agcctacctc cgcatccacg cgcacttcac tgggctcagg
    22201 tgaggggcca actggagtga accttgggca actcttcacg ggggctaacc ttccaccaag
    22261 agggtcccaa gcagaggtaa tgggtttaca gagcagagct gacttgggtt tcacataggc
    22321 cagagggtct caaagctgcc acatattggc ctatcagctc cctggggaac ttttatctag
    22381 gcatcagaat ttttaatttt tgttttttgt ccccccaacc ctccatcatc cctgttcatc
    22441 ttccctccgc cctgccatcc acccagaaat ccagggctaa gggctccacc caagtgagca
    22501 gaattttttt tttttttttt tttaagaggg ggtcttgctc tgttgcctag gctggagtgc
    22561 agtggcgcga cctcggctca ctgcaagctc tgcctcccgg gttcacacca ttctcctgcc
    22621 tcagcttcct gagtagctgg gactacaggc gcctgcgacc acacctggct aatttttttt
    22681 gtatttttgg tagagatggg gtttcaccgt gttagccagg atggtctcaa tctcctgacc
    22741 ttgtgatccg tccaccttgg cctcccaaag tgctaggatt acaggcgtga gccaccgcgt
    22801 ccggcctgtg agcagaatgt tttaaagcac cccgaggaag gctgatgggc tgacagaatt
    22861 aagagctact cttttgaacc gttggcttag caagagttgg ggtgactctt gagagacaga
    22921 caacattgag gctgtggcat atggccctcc cacaggagac ttcccaaggt ccttggcctt
    22981 tgttagaacc tggtatagca ggttctggaa actgtgtggg tgggaggcag gggtgacaga
    23041 gccagctgta accaaactca cttgaattgc cctagaaatt atttctggga catgagaagg
    23101 ctggtgctct ctggtaactg ctactacctt cttgtcccta cttcctgcct cagatacctg
    23161 ctatacaact tcccgatgac ctgcgccttc ataggtgttg ccagcaactt caccttcctc
    23221 agcgtcatcg tgctcttcag ctacatgcag tgggtgtggg ggggcatctg gccccgacac
    23281 cgcttctctt tgcaggtcga aaggggcaag gacccccttt tgtccctttg atctttgtgg
    23341 gtggtcaggg gtatgttggg gattaaggca tgagggtcct gattgttagt gagggaagtc
    23401 agtcctggct gctcagtagt ttttcctcca caggttaaca tccgaaaaag agacaattcc
    23461 cggaaggaag tccaacgaag gatctctgct catcagccag gtaaaggtgt tggctgggga
    23521 gctgttgagg tgggctaggt tgagctgggc tgggccagaa ggagtccctg cttcatccag
    23581 tatgaggctt agggtatcac cgactgagac aagggtcaaa ggaaaggcga ggaaggtgag
    23641 gttggcactg ccgtccaggc acagccaccc taaccctaac ctgtcctctc cctctttgga
    23701 ggtgcagggc ctgaaggcca ggaggagtca actccgcaat cagatgttac agaggatggt
    23761 gagagccctg aagatccctc agggacaggt atggcgcagc caccacactc tctccttcct
    23821 gactccttgg ctttctcctt cagtgtctgg gtctgacccc tgcattcccc ttttggctgc
    23881 agagggtcag ctgtccgagg aggagaaacc agatcagcag cccctgagcg gagaagagga
    23941 gctagagcct gaggccagtg atggtgaggg gcatcctgca gcgtgacctg ggtggggccc
    24001 ccggttaatc taatatccca tttgagattt tgtttttccc tttcctggcc caggttcagg
    24061 ctcctgggaa gatgcagctt tgctgacgga ggccaacctg cctgctcctg ctcctgcttc
    24121 tgcttctgcc cctgtcctag agactctggg cagctctgaa cctgctgggg gtgctctccg
    24181 acagcgcccc acctgctcta gttcctgaag aaaaggggca gactcctcac attccagcac
    24241 tttcccacct gactcctctc ccctcgtttt tccttcaata aactattttg tgtcagcttc
    24301 ttccttgact ctgaaatggg ttcagggcca tttgaacacc ctgtgtcccc catgcatctc
    24361 tcactttccg ccattagagg ggaggtcttc ttgtccaggg gaaggcctcc agacctgggc
    24421 tattttaagc acagatgttt ccattcataa gcctaggaag tccaaggagg gagaagctat
    24481 cctggcccct agcaagcttt cccactccct gcatgtgact ttcatctccc ccagaggagg
    24541 gggatggtgt agggcaggtc tgcagagctg ggagacatca ttctggcccc ctctacaccc
    24601 ctcccttcct cccttcctcc ctttctctgt ccattgggag gcagaagaca ggaaatgact
    24661 gccatggatg tggtaggatt tttaccaaaa cagcattttg cggctcaggc ccgtgctgtt
    24721 cgcagctgtt ttcctctaat atcagccagg tggccgcctt ctatgttccc ctccccatcc
    24781 cgttgtatga cttcagcctt cggattctaa gctcctggct gctttccaca ttccactccc
    24841 cttccagaac ccaggcatcc tgggctccag ctgaaaccat tgcatgtggc tttccccatc
    24901 cctggccccg tgactcagtc cctctgaagg gagcagccct cttttttggc aatcaccagg
    24961 gaggtggggg gaggaggagg ggagctaggt ggtgacatca cagtcgaagg ttataaaagc
    25021 ttccagccaa acggcattga agttgaagat acaacctgac agcacagcct gagatcttgg
    25081 ggatccctca gcctaacacc cacagacgtc agctggtgga ttcccgctgc atcaaggcct
    25141 acccactggt gaggagctgc tatgggccag agaggaggag ggaggcatgc aggggccagg
    25201 actccttgga caggatttgc acagatagca ggtggggagg gaggattcca gcgtccctat
    25261 ttttttctct tgttttcaaa aaatacagct gtgcttacaa tatttctcca ttctgttctc
    25321 ttttctcaac tctgtctcct ttctgggttt ttgcctgtgt cactgacgga tacatgtttt
    25381 tgttgagttg aggtctcact cttgtcaccc aggctggagt gttgtggggc gatcatggtt
    25441 cactgcagcc ttgaactcct gggctcaagt gatcctcctg agtagcaggg accacaggca
    25501 tgtgcagtat atttttaatg ttttttaact ttttaataat ttttaaatac tttttaattt
    25561 ttgtagagat ggggtctctc tgtgttgccc cagctggttt ggaatcctgg cctcaagcaa
    25621 tcctcttgcc ttgacttccc caaagtgttg ggattatagg catcagccta ggggcccggc
    25681 tttgttactt gttttgctta gatcttttct ctgggtggca gctagtaaat atcctaccgt
    25741 tcttccctgg gctaagtaaa tcatgtcctc ctcttctctc cctcagcact ttgtttattc
    25801 attaactgtt tctaatactt aacacatgct gatcatgcat ctgtctcatg tgtcagatca
    25861 tgttttattt tttgtctgaa accaagcaca cagcctggac tcagaagttg gttgacaaat
    25921 gagtgtgtct gcctcattcc aacttctttc ctcttctgat ccccagttgc attttcctgt
    25981 ctccagagat tgtgtccagg cagagggcat ggcaggcttt tgggctgaac aggctttatc
    26041 tatccacccc ttcccttcca gtctccatgc tgggctctcc ctgccttctg tggctcctgg
    26101 ccgtgacctt cttggttccc agagctcagc ccttggcccc tcaagacttt gaagaagagg
    26161 aggcagatga gactgagacg gcgtggccgc ctttgccggc tgtcccctgc gactacgacc
    26221 actgccgaca cctgcaggtg ccctgcaagg agctacagag ggtcgggccg gcggcctgcc
    26281 tgtgcccagg actctccagc
//

