LOCUS       NG_033202               9319 bp    DNA     linear   PRI 03-APR-2013
DEFINITION  Homo sapiens UDP-GlcNAc:betaGal
            beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1), RefSeqGene on
            chromosome 11.
ACCESSION   NG_033202
VERSION     NG_033202.1  GI:474451734
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AP001107.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes a member of the
            beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a
            type II transmembrane protein. It is essential for the synthesis of
            poly-N-acetyllactosamine, a determinant for the blood group i
            antigen. [provided by RefSeq, Jul 2008].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9319              AP001107.5         83628-92946         c
FEATURES             Location/Qualifiers
     source          1..9319
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.2"
     gene            5001..7319
                     /gene="B3GNT1"
                     /gene_synonym="B3GN-T1; B3GNT6; BETA3GNTI; iGAT; iGNT"
                     /note="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 1"
                     /db_xref="GeneID:11041"
                     /db_xref="HGNC:15685"
                     /db_xref="MIM:605517"
     mRNA            join(5001..6201,6451..7319)
                     /gene="B3GNT1"
                     /gene_synonym="B3GN-T1; B3GNT6; BETA3GNTI; iGAT; iGNT"
                     /product="UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 1"
                     /transcript_id="NM_006876.2"
                     /db_xref="GI:92091577"
                     /db_xref="GeneID:11041"
                     /db_xref="HGNC:15685"
                     /db_xref="MIM:605517"
     exon            5001..6201
                     /gene="B3GNT1"
                     /gene_synonym="B3GN-T1; B3GNT6; BETA3GNTI; iGAT; iGNT"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             join(5146..6201,6451..6642)
                     /gene="B3GNT1"
                     /gene_synonym="B3GN-T1; B3GNT6; BETA3GNTI; iGAT; iGNT"
                     /EC_number="2.4.1.149"
                     /note="i-beta-1,3-N-acetylglucosaminyltransferase;
                     UDP-GlcNAc:betaGal
                     beta-1,3-N-acetylglucosaminyltransferase 6;
                     beta-1,3-N-acetylglucosaminyltransferase bGnT-6;
                     poly-N-acetyllactosamine extension enzyme"
                     /codon_start=1
                     /product="N-acetyllactosaminide
                     beta-1,3-N-acetylglucosaminyltransferase"
                     /protein_id="NP_006867.1"
                     /db_xref="GI:5802984"
                     /db_xref="CCDS:CCDS8136.1"
                     /db_xref="GeneID:11041"
                     /db_xref="HGNC:15685"
                     /db_xref="MIM:605517"
                     /translation="MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQDQ
                     YFEFFPPSPRSVDQVKAQLRTALASGGVLDASGDYRVYRGLLKTTMDPNDVILATHAS
                     VDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSHCPDMRARVAMHLVCP
                     SRYEAAVPDPREPGEFALLRSCQEVFDKLARVAQPGINYALGTNVSYPNNLLRNLARE
                     GANYALVIDVDMVPSEGLWRGLREMLDQSNQWGGTALVVPAFEIRRARRMPMNKNELV
                     QLYQVGEVRPFYYGLCTPCQAPTNYSRWVNLPEESLLRPAYVVPWQDPWEPFYVAGGK
                     VPTFDERFRQYGFNRISQACELHVAGFDFEVLNEGFLVHKGFKEALKFHPQKEAENQH
                     NKILYRQFKQELKAKYPNSPRRC"
     exon            6451..7319
                     /gene="B3GNT1"
                     /gene_synonym="B3GN-T1; B3GNT6; BETA3GNTI; iGAT; iGNT"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     gene            7580..>9319
                     /gene="BRMS1"
                     /note="breast cancer metastasis suppressor 1"
                     /db_xref="GeneID:25855"
                     /db_xref="HGNC:17262"
                     /db_xref="MIM:606259"
     mRNA            7580..>7719
                     /gene="BRMS1"
                     /product="breast cancer metastasis suppressor 1,
                     transcript variant 1"
                     /transcript_id="NM_015399.3"
                     /db_xref="GI:68348700"
                     /db_xref="GeneID:25855"
                     /db_xref="HGNC:17262"
                     /db_xref="MIM:606259"
     mRNA            7580..>7719
                     /gene="BRMS1"
                     /product="breast cancer metastasis suppressor 1,
                     transcript variant 2"
                     /transcript_id="NM_001024957.1"
                     /db_xref="GI:68348701"
                     /db_xref="GeneID:25855"
                     /db_xref="HGNC:17262"
                     /db_xref="MIM:606259"
ORIGIN      
        1 aaattagcca ggcatggtgg cgcacacctg taatcccagc tactctggag gctgagacgg
       61 gagaatcgct ggaacccagg aggcagaggt tgcagtgagc cgagatcatg ccactgcact
      121 ccagcctggg tgacagagcg agactctgtc acaaacaaaa caaaacaaaa caaaacaaaa
      181 agaattaaca acaatcctat aacagtgtag tgtgcaaagt aaaaagaaat ttacaacaat
      241 ccttctcaaa ctcttccaaa aaatagaaaa cactttacaa ctcattctat gtgacctgag
      301 gccaaactaa tatacagacc atcccaagaa aactacagac cgtatctcat atgaatatag
      361 atgcaaaaat cctccacaaa atactagcaa acctaaccca gcaacatatt aacagaatta
      421 tacaccatga ccaagtagga attattccag aaatgcaaga ttgtttaaca tacaaaaatc
      481 aatcagtgtg gccgggcacg gtggctcacc ctgtaatccc agcactttgg gaggctgaag
      541 caggtggatc acttgaggtc aggagtttga gaccagccta gacaacatgg tgaaatccgt
      601 ctctactaaa aatacaaaaa atattagctg gctgtggtgg tgcacacctg taatcccagc
      661 tagtcaggaa gctgaggcag gagaatcact tgaacctggg aggtagaggt tgccatgagc
      721 caagatcgcg ccactcactc caacctgggt gacagagcga gactccatct caaaaaaaaa
      781 aaaaaaaaag aaaggctggg tgtggtggct catgcctgta atatcagcac tttgggagac
      841 cgaggcgggc agatcacttg aggtcaggat ttcaagacca gcctggcgaa catggtgaaa
      901 cggcatctct actaaaaaat acaaaaatta gccaggcatg atggcgcatg cctgtaatcc
      961 cagctactcc ggaggctgag gcatgagaat aacttgaacc caggacgcag aggttgccgt
     1021 gagccaagat cgctccactg cactccagcc tgggaaacag agcaagaacg tctcaaaaaa
     1081 agaaaaagaa aatcaatcaa tgtaatacac cacattaata gaatgaagag gaaacaccaa
     1141 gtgatcacct caatttatga acaaaaagca agtgacaaaa tccaacacgc tttcaagata
     1201 aaaagcatgt gacaaagtcc aacactcgtt caagataaaa agcatgtgac aaagtccaac
     1261 actcgttcaa gataaaaatg ctgaataaac aaggaatagg tggaaacttc cttcacctga
     1321 taaagggcat ttatgaaaaa tccacaaata acatcatact taatggcgaa agacctaaag
     1381 ccttccccca aagatcagga acaagagaag gatacgtggt ttcaccgttt catctcctca
     1441 acattgtact agaagttcta gctagagcaa tttggcaaga aatgaacttc tgcactgggg
     1501 tgggaaaaaa aatggcaaga aaaagaaaca aaagttaacc aaactgaaaa agaggtaaaa
     1561 ctattcatag tcacagatga cataatatat acatatatag aaaatcctaa ggaatacatg
     1621 catacacaca gagacacaca cacacacaca cacagacacg tacacacata cacaaacttt
     1681 tagagctaat aaagtcagca aagttgcaga attcaagatt aacacacaat agcctggctc
     1741 agtggctcgt gcccgtaatc caagcacttt gggaggctga ggtgggtgga tcactcgagg
     1801 tcaagagttc aagaccagct tggccaacat ggtgaaaccc tgtctctact aaaaatataa
     1861 aaattaactg ggtgtggtgg cgcacgcctg tagtcccagc tactagagag gctgaggcag
     1921 gagaatcact tgaacctaag aggcggaggt tgcaatgagg tgagatcact ccactgcact
     1981 ccagcctggg agacagagtg agactctgcc tcaaaaaaaa aaaaaaaaag ttaacacaca
     2041 aaattctggt tgggcacagt ggctcatgcc tgtaatccta ccactttgtg acgctgaggc
     2101 aggtggatca cctgaggtca ggagtttgaa accagcctag ccaacatggc aaaaccccgt
     2161 ctctactaaa aatacaaaaa ttagccgggt gtggtggcat gcacctgtag tcccagctac
     2221 tcgggaggtt gaagctggag aattgcttga acccgggggg cagacgttgc agtcagccaa
     2281 gatcgcgcca cttcactcga gcctgggtga aagggcgaaa ctccatctca aaacaacaac
     2341 aacaacaaca aaaattcagt tatatttcta tacactaaca atgaacaacg tgaaaaggaa
     2401 attaagaaaa caactccatt tacaatagga tacaaaagaa taaaatacct aggaaaaaat
     2461 taacccagga agtaaaaaac ttgtccactg aaaatacaaa cactggctga gcttggtagc
     2521 tcactcctgt aatcccagca ctttgggagg ccgaggtggg cagatcacct gaggtcggga
     2581 gttcgagacc agcctgacta acatggagaa accctagtct actaaaaata caaaattagc
     2641 tgggcatggt ggtacatgcc tgtaatccca gctactccgg aggctgaggc aggagaatca
     2701 cttgaaccca ggaggcagag gttgcagtga gccgagattg agccattgca ctccagcctg
     2761 ggcaacaaga gcgaaactct gtctcaaaat aataataata ataatagggc tgggcgcagt
     2821 ggctcacacc tgtaatccca acactttggg aggccaaggt gagtggatca cctgaagtta
     2881 ggagttcgag accagcctgg ctaacatgat gaaaccccat ctctactaaa aaataataca
     2941 aaaaattagc caggcatggt ggtgcactcc tgtaatccca gctactcagg aggctgaggc
     3001 aggagaatca cttgaaccta ggaggcaagg ttgcagtgag ccaagatcgc gtcattgcac
     3061 tccagcctga gcaagaagaa caaaattctg tctcaaataa taataataat aataaataaa
     3121 aaataaaaca ctgaggaggt caaagaaaat ccacatggca gcatgtctga cttctgagcc
     3181 tccagtctat aaggcctgtg ctgaaaggat ctgcacttac ttttctcctc tttacagcca
     3241 aggtcaccag tggaaactct caaggacaat acctgtgtct cctccaaggc ccatccctcg
     3301 tgcctaacac agttcctggc agagaccagg tactcagtgt gtgtttttgc tctgggctgc
     3361 aaaataaagg ttttctgatc actcttcaac tcaacaacct tggcacccta ctgcctgtgg
     3421 aatagtggga caaacacttt atccttattt gaagccctgc ccagtctgtc ctgacatccc
     3481 aagattcaga gcactctgcc ctataggggc ctccctggct cagcctaaaa agttgagtaa
     3541 tatacggtaa ttgatttagc agtggcagtg tctgcccttc ccacggcctc tcctgttcta
     3601 aagagtccac agatgaatta atccacaaat acttattaag agtatagtgg cctgatattg
     3661 gaatgttcaa agccttctgc ttaagagttt gtgtgcggcc gggcgcggtg gctcacacct
     3721 gtaatcccag cactttggga ggccgaggtg ggcggatcag gaggtcagga gatccgagac
     3781 catcctggct aacacggtga aactccgtct ctgctaaaaa tacaaaaaat tagccgggcg
     3841 tgctgcatgc gctagtagtc ccagctactc ggggctgagg caggagaatc gcttgaacct
     3901 ggaaggcaga ggttgcagtg agccgagatc gcgccactgc gctccagcct gggcgacaga
     3961 gcgagaatcc gcctcaaaaa aaaaaaaaaa aaaaaaaaaa gagattgtgt gtgttgggga
     4021 gcagggcatg tggacacaag gtctccgccc taggagaagt gctggagagt aggacaagta
     4081 ccactacttc ggacggggag ggcgatgcct ccaatggggg gcttccctga ttcctgcaga
     4141 tcatacgttg gcccccaact tcacactggc cagaatcccg gttctagtct tttccgtgcc
     4201 accaacccct gggccctctt tctagaagga aagaaaacac ctttggcctc tgcccagagc
     4261 tacagacacc tgaagtagga gcaggcagga gatgcgtggt ggataaagac cagagagact
     4321 tgggatcgaa ttccactctc acccccagtt cagttttctt cagcttgctg ctccacaggc
     4381 aggatgtgaa aatttagatg cctcacccct cgcacctcca gcttgctgct ccaaataggc
     4441 aggatgtgaa aatgtagatg cttccccccc aacctctata aaacagggcc gacgaggatg
     4501 ggattcgaac ccacgcgtgc aaagcacaat ggattagcag tccatcgcct taaccactcg
     4561 gccacctcgt cctacgtgac aggtttgtcc acattcactt atctctcatc tactccgcac
     4621 cttccaagca ctaccacgta agtcgcaacg cagacctctt cggacacagg gaaagaagaa
     4681 gccgcggaag gaagggagcg ttttgatttc ctttctgctg agcccgcgcc atcctttacc
     4741 acgctgcagc cgagctctgc cgcggtttcc ctccgagtcc ggccgagcgc gccgcgcgtt
     4801 cagggcgcgc ccggtccagg gtgcgcgcgc cggcggggag ggagaggagt gcgtcccggg
     4861 aagccggcgg ggcccgggcg ggcgggcgtc tgcacggcgc gcggccgagc ggcggggccg
     4921 tggctcctcc tccctcgtag ggggcgagcc ggcgcgccgg gggctggggg cggtggcggg
     4981 cggcgggcgg cgggcggcgg gcggcgggcg gggcggcgct cggggctcgg ctggcctcgg
     5041 ctcgcctcgg ctgcgctcgg caggctgcgg taaatccggg cttgcggccg ctggcgtagt
     5101 ctgtggccgg gtggtcgttg ctgcgcgccc cgagccccga gagccatgca gatgtcctac
     5161 gccatccggt gcgccttcta ccagctgctg ctggccgcgc tcatgctggt ggcgatgctg
     5221 cagctgctct acctgtcgct gctgtccgga ctgcacgggc aggaggagca agaccaatat
     5281 tttgagttct ttcccccgtc cccacggtcc gtggaccagg tcaaggcgca gctccgcacc
     5341 gcgctggcct ctggaggcgt cctggacgct agcggcgatt accgcgtcta caggggcctg
     5401 ctgaagacca ccatggaccc caacgatgtg atcctggcca cgcacgccag cgtggacaac
     5461 ctgctgcacc tgtcgggtct gctggagcgc tgggagggcc cgctgtccgt gtcggtgttc
     5521 gcggccacca aggaggaggc gcagctggcc acggtgctgg cctacgcgct gagcagccac
     5581 tgccccgaca tgcgcgccag ggtcgccatg cacctcgtgt gcccctcgcg ttacgaggca
     5641 gccgtgcccg acccccggga gccgggggag tttgccctgc tgcggtcctg ccaggaggtc
     5701 tttgacaagc tagccagggt ggcccagccc gggattaatt atgcgctggg caccaatgtc
     5761 tcctacccca ataacctgct gaggaatctg gctcgtgagg gggccaacta tgccctggtg
     5821 atcgatgtgg acatggtgcc cagcgagggg ctgtggagag gcctgcggga aatgctggat
     5881 cagagcaacc agtggggagg caccgcgctg gtggtgcctg ccttcgaaat ccgaagagcc
     5941 cgccgcatgc ccatgaacaa aaacgagctg gtgcagctct accaggttgg cgaggtgcgg
     6001 cccttctatt atgggttgtg caccccctgc caggcaccca ccaactattc ccgctgggtc
     6061 aacctgccgg aagagagctt gctgcggccc gcctacgtgg taccttggca ggacccctgg
     6121 gagccattct acgtggcagg aggcaaggtg cccaccttcg acgagcgctt tcggcagtac
     6181 ggcttcaacc gaatcagcca ggtgctcata agggagaggg caggggtaat ggggcaggag
     6241 gggtggtggg atcagggagt tatgaggagt ggccctggat ggaaaggagg caatgaagca
     6301 ggagggatca tagttcagga ggtgggtgga tggtgtggaa gatccaggat acttccagag
     6361 gggtgaggac gctggactgt ggctttaggg aagtcagtct caggcctgtc aatgtcatca
     6421 aactttgcta acctgtcttt cctcctgcag gcctgcgagc tgcatgtggc ggggtttgat
     6481 tttgaggtcc tgaacgaagg tttcttggtt cataagggct tcaaagaagc gttgaagttc
     6541 catccccaaa aggaggctga aaatcagcac aataagatcc tatatcgcca gttcaaacag
     6601 gagttgaagg ccaagtaccc caactctccc cgacgctgct gagcccttcc ctcccctaat
     6661 ctgagaagtc agcctcttgg ctcctcaggc caccatttag gcctgactgg ggtaagaaat
     6721 gtcgctccac tttacagagg tagctgtggt gttgaaacac tggacttgga tatggggtgc
     6781 tgggatcgat tcctagcttt accactaact agctgtgtgg ccttgagtaa atcccgttac
     6841 ctctctgagc ctcggttacc ctgtctgtaa aaagggaggt gagaatacct acctcacgga
     6901 actgttggga ggctcagatg agatgctata tgtgaaaaca ttctgtaagc ttcgtacaaa
     6961 tgtgaagtat taatattatc gcagtattat tgttgttatt attattgtta ttattaacaa
     7021 tcttgggtgg gtagtaggag agcaaaaagt atgaatggga tggagctaag aagtctgaat
     7081 acttaatgaa atggactttt tggaaagaaa tcagatgaag gcataaaatt tagttcttag
     7141 ctcttgaaca gaagcctaaa attcctggtt ctctcagggc ttcgccttca agggttctgg
     7201 aggagggaag ggtctgcagg ttccatgggt gacagcctga gatctgtccc ttcaacgggc
     7261 tgggctgggt atgtgcctac cgatgacaat gtgtaaataa atgcgtgttc acacccacag
     7321 ctggctccgt tactctcctg agctgggggt ggggggatcg gggccggctt ctccccttgc
     7381 acgccgtggg gagatggccg cggacgaagg gcaccgtctg caaagcactg aaccatcagg
     7441 gccttccctg caggccgaag gcctgcgcga atgtcggcca gttactatgg agaccggccc
     7501 gcggtatccc agcatgcctc gggaccaaac tgtccaactg tgagcatccc cgacggtcgc
     7561 ctcctgatga cgcacacgga agcaccgata ggctctgcct cccgaagaaa agggagccgc
     7621 gcagcgccta cgggagtccg gcggcagcag ccggtaccgg caaccacggg cagctctcag
     7681 ggaatctccg tcgtgaggcc agaggctcca gtccccgcgg tgcgtatcgt catgcatggc
     7741 ttttggttcg ccctctccgg ttagtcgagc agggccggca caacctcctc ctccgaggcc
     7801 gaagcagaga tttaaccggc ctgacgcgtg ctgggctgcg ggcgagccag tgatattccg
     7861 gcccgctccg gcgcatctag aagggagcgg gaggccccct gggcgctgcg gagaagctgg
     7921 attgacctct gcgagagtgg ggagggtctg ccttccctag gggcctgccc cggaggagct
     7981 gccattctga aaagataaat tgcctgtgta cagcgcttta cagtgtgctt ttccatccct
     8041 taccacctgt gagctcctca acactcagag caggaatggt tatccgcttt ttgcacccgg
     8101 ggtaaggtgg gaaggttgtg acttaactca ctcataatca gaaccagggg gaggaaagaa
     8161 aggcttctgg aagagataga cttaagctgc atcttacaaa gtgaatatac taacagtgaa
     8221 gaggcattgc aaatgttggg aactgaggct tgataacggg aagatgaagc tggtttagag
     8281 aaccgagcct ttcaagtcag gtgcaggtca ttagtgaaat tgttgaggaa tatgactaaa
     8341 cactcaccta ggccaggctt actatacaca acttgaactg gtgtcaagga aagcttgcta
     8401 ccattacagg gacctgggac taccgaaaag taaaaactaa tgtctgtctc acaaaaaatt
     8461 tttttgttaa atttgtattt gcaaatcctc cagtcatcaa gtgaaccagc actgtgctag
     8521 gtaaataagt tacatgtgca gcccctgccc tagtgaggct catagactga ttgcggggac
     8581 agatatgaga acaggcaaat agatataaac aaagcttcct ggagggagtg gtgtctgcac
     8641 tgttctaaag gactacaaag cagtgtccag agaagttgga agaacacaat aaaatagaag
     8701 cctgcaggag gttgagagat tatctgctga gaggactgtt ttcttcttct taggtgatct
     8761 cttggcagta cttggcacta tcagtgcaat tactccttgg cagtacttgg ctttcttcta
     8821 aaactctttc tccaccactt cgggttttgc ctcctccttt gtaggggtct cctcatctgc
     8881 ccctttggtg accctgggcg tcttctgatc gcacacattg tgccttgctg gttgcacctt
     8941 ctcctgtggc atgaagaact tgctgtatgc tgacgaccaa atccctgcag ctcagatttc
     9001 tcactgagac ttagacccat gttcccccag ctgctttcct tctcttattt ctgggtcttt
     9061 gctactgact ctacctggaa tgttccctca ataagtgcag ctcacccagc tggtccatct
     9121 ttgtctggaa gcctccctgc tgcatcgggc tccaggtcct ggttatatac ccctccctta
     9181 tgcccctggt cttaactctc ctcctatcat ggttatagtg tgctcctttg cccctgtctc
     9241 ccaggaactt gtaaactccg tgaggtcaaa gacattcaca cttgggcgcc tgcataccat
     9301 agcgtctgac ggtacctag
//

