LOCUS       NG_023227              16176 bp    DNA     linear   PRI 29-JAN-2013
DEFINITION  Homo sapiens ankyrin repeat domain 1 (cardiac muscle) (ANKRD1),
            RefSeqGene (LRG_379) on chromosome 10.
ACCESSION   NG_023227
VERSION     NG_023227.1  GI:300069053
KEYWORDS    RefSeqGene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with James Ware, Johan den Dunnen. The reference
            sequence was derived from AL365434.13 and AL590622.7.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene is localized to the
            nucleus of endothelial cells and is induced by IL-1 and TNF-alpha
            stimulation. Studies in rat cardiomyocytes suggest that this gene
            functions as a transcription factor. Interactions between this
            protein and the sarcomeric proteins myopalladin and titin suggest
            that it may also be involved in the myofibrillar stretch-sensor
            system. [provided by RefSeq, Jul 2008].
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4568              AL365434.13        101-4668            c
            4569-16176          AL590622.7         38504-50111         c
FEATURES             Location/Qualifiers
     source          1..16176
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.31"
     gene            5001..14176
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /note="ankyrin repeat domain 1 (cardiac muscle)"
                     /db_xref="GeneID:27063"
                     /db_xref="HGNC:15819"
                     /db_xref="MIM:609599"
     mRNA            join(5001..5275,5928..6107,7008..7145,7304..7411,
                     8446..8544,10007..10105,10396..10494,10635..10733,
                     13300..14176)
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /product="ankyrin repeat domain 1 (cardiac muscle)"
                     /transcript_id="NM_014391.2"
                     /db_xref="GI:38327521"
                     /db_xref="LRG:t1"
                     /db_xref="GeneID:27063"
                     /db_xref="HGNC:15819"
                     /db_xref="MIM:609599"
     exon            5001..5275
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=1
     CDS             join(5249..5275,5928..6107,7008..7145,7304..7411,
                     8446..8544,10007..10105,10396..10494,10635..10733,
                     13300..13410)
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="similar to AA sequence (same
                     species):RefSeq:NP_055206.2"
                     /exception="annotated by transcript or proteomic data"
                     /note="cardiac ankyrin repeat protein; liver ankyrin
                     repeat domain 1; cytokine-inducible gene C-193 protein;
                     cytokine-inducible nuclear protein"
                     /codon_start=1
                     /product="ankyrin repeat domain-containing protein 1"
                     /protein_id="NP_055206.2"
                     /db_xref="GI:38327522"
                     /db_xref="CCDS:CCDS7412.1"
                     /db_xref="LRG:p1"
                     /db_xref="GeneID:27063"
                     /db_xref="HGNC:15819"
                     /db_xref="MIM:609599"
                     /translation="MMVLKVEELVTGKKNGNGEAGEFLPEDFRDGEYEAAVTLEKQED
                     LKTLLAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKT
                     KVPVVKEPEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRA
                     CLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKL
                     LSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGA
                     DLNIKNCAGKTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF"
     exon            5928..6107
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=2
     exon            7008..7145
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=3
     STS             7087..8481
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="ANKRD1-1"
                     /db_xref="UniSTS:509947"
     exon            7304..7411
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=4
     exon            8446..8544
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=5
     STS             8517..10030
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="Ankrd1"
                     /db_xref="UniSTS:531324"
     exon            10007..10105
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=6
     exon            10396..10494
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=7
     exon            10635..10733
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=8
     exon            13300..14176
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /inference="alignment:Splign:1.39.8"
                     /number=9
     STS             13447..13668
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="SHGC-35401"
                     /db_xref="UniSTS:52873"
     STS             13449..13645
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="STS-X83703"
                     /db_xref="UniSTS:29025"
     STS             13474..14176
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="ANKRD1_9516"
                     /db_xref="UniSTS:468279"
     STS             14000..14086
                     /gene="ANKRD1"
                     /gene_synonym="ALRP; bA320F15.2; C-193; CARP; CVARP;
                     MCARP"
                     /standard_name="RH98636"
                     /db_xref="UniSTS:92563"
ORIGIN      
        1 aaaataaaat aaaataaaaa ataaatgagt aaattgtatg tgtgtgtttc ccatggtctt
       61 agcataggca agagtcttca acaatcaaaa ttctgagacc agaataacaa tagcttgact
      121 gtccactaca acttggagaa aatacacgtg tatttagata catattcatt taattctaca
      181 ccctcgagca gtattctcaa tgctgggagg aaattagaat caactggaaa actttaaaaa
      241 ataccaattc cttggatctt tgagcagaga tttggatttc atgtgcctga gctgaagcct
      301 gggcatcagc atttttttag aagcttcaca gaggattcta agatgcaccc agcttagaga
      361 atcactgctt gaagaaatgt tagttcacac ctgagaagcc ctgactctgc gattacaact
      421 gttggggtta gttagcattt gaaagacact aatgagctgc ccccactcca gtggaggtaa
      481 tcccaagtac tttacctatc tttacctttg atagtattga cagattaatg gttaattagc
      541 atgagaaatg ttaccaatta tttctcattg aaaggagaat ttgaaatatg tggtttggtt
      601 agaaaagaat atgagccctg ctgggtctca ggtaaatatt tatttagccc cactatgtgt
      661 caggcacttt tctatgcagt tggagtccta ggcttatagt gagtgctagg actccatcct
      721 atcttgtgtt aggccatatg tggaggagtc tgtaatcacc ttgagtggac tagaaaatta
      781 gctgaaatat gctgccagaa tgtggttgtg gtttcatttg cttcaagtga aactttttct
      841 tttatttttt tttaaataaa aaaacataga gccaggatct cgctatgttg tctaggctgg
      901 tctcgaactc ctagggtcaa gtgatcctcc tgccttggcc tcgcaaagtg ctgaggttac
      961 aggcatgagc caccatgcct agtcaagcga atcttttgtg ctggacactg tccaagggcc
     1021 taaatggaca aagggctggg cttcatgagt ttactgaata gtgcatgtgg ccctttgtgc
     1081 ctgttggctg gtgtgagttc atatgtgtgg cagaatttgc actgagatac cttatttact
     1141 gtaacaaggc acctgctgta aggtgtggag gtgagaccta cagccttcac ctacctctaa
     1201 cgtcaggagg ccaccgatat ccgtaaaaag taacctactg tgggcagccc aactgtgtta
     1261 gggcagtttg tgccctttct atccagagtc ctgggcagaa ggactttagt cttgattctg
     1321 cctttcgaga ggcaaggaag gcaggtgcca caatcctgct gaaaatgttt ccagtacttt
     1381 tctgcttttc aaatacaggt tatcccattc ctggcagggg aggggaaaca acattaaacc
     1441 ttatttgctt cacttttatg accttccttt ggcattttca aacacgtaac tgagccatgg
     1501 cttgctggtc aggctaagtc agccacttct ctgggccaag gaaggtgcgt aacagctggg
     1561 actgggaagg ctattaaaag ggatggcaaa atgagcaatt gtaagtacaa cagtggaaca
     1621 aggaggtttc caagtcagaa tctggctaca gtccttggag cacttccttt tagtatcaag
     1681 ttgggtgttc taaggacaag gagtgttaat aacaataaaa ttttatgtgc tataaaatgc
     1741 ctttttagaa aataaaaatg cccattttaa aaaaacagcc tacatgtcca caaatgagaa
     1801 agtggttaaa taagaaatgg taggtccgtg catggaaatt catgcagttg tttctaatag
     1861 caagatagat ttgtttgtgc agataggaga caatctgtaa gacacggtta ctgagcgaaa
     1921 aataatcaag tatcaaatcg acagtaagat ctgaactaaa taacattctc tgtgctattt
     1981 ttaacaataa tgtgtctatt atatagttaa aatataagaa tgaaaagttg gagtagaagt
     2041 agaacgtctg gaacttcata ttttatacag aaagataaaa ctgcccttgg acttggagct
     2101 gagctatggc acatggatct gggtggggtc caagcgcctc ttttaatccc taggtgacag
     2161 cagtaattgc tttaggtgct acttctctgc ttctcacttt ctccagctat aaccatggtc
     2221 ctaattctag tcacatgtca tttcacccat ggaaatgcat aaatcctgag gggagtggga
     2281 aaaggctcat ggggtgacac tggagaagct cagggatgct tcctttactc tttctggttg
     2341 gagatgggtg atgccaagtt gctttatgat tgtagaacca actaggacct ttattgtttt
     2401 aattcatctt agtaaggata gattatgtcc agattgaggc tatgataaag ccaaatacac
     2461 aaatataaga atttacacca ctgggtgaac ttttatggga aggatgcttc tgaaaaacaa
     2521 atgacagaaa actctccgcc aggggaattt ttttctcaat tttgatgaat aagaacgatt
     2581 tgaaaataca atggttgttg tttttatctt tttagagagc taaaggtgcc tagaatctct
     2641 tttcaaaaag cagattctct catgtttttt ttctttattt gttgtcatat tctttttaca
     2701 tcttctgacc acttatcctc aagttgtacc tctcatgttt tataatgaca agctggatca
     2761 acatgggaaa aggttgaact ggcagtgatt tcaccagccc tgacatcctt gcatccacca
     2821 gcgtgctcct ttaagttcag cccattccat caactcatct tcaagtgtca tcctctgcaa
     2881 agttttcttc aagacttcct ggagcctctc tatagaatca gctaggtttc aagggataat
     2941 taaatgcctg gagaaagaaa agggcttggt aagcctccct gcccactttc acttgcattc
     3001 tttgaggtga ttgaaacagt aaggagccat ttaatcagtt ttggttgcat cctgagtggg
     3061 tctaggtgag acttgcccta ggaaatcttt tgggctcaat gattgtctgc ttctgttgga
     3121 tggaatcagg actcttcaac ctagcattca ccaactagct gtgcatctgc agcaagttac
     3181 ttaatgtttc tttgcctcag catcctctct gtaaaatgag agcattagtc ttgctccaac
     3241 ttcgagggca tggacagctc tgggatttca tatccaagac ccttaaacat cccacagtcc
     3301 ttcccccaaa cacttctcct cctaatacct ccctcagttt gggtcaggcc tggaacaaaa
     3361 aggcatacga aatggtagaa aaagtgtcca tgactacttc tgacttagat gaagagacca
     3421 atgaaaatag taatgactct gtttgcttca gcaggacata tactaaaata ggagctatac
     3481 aaagaagatt agcatggact ctgtgcaaga atgacacaca aatttgtgaa acattccata
     3541 tattaaaaat aaataaataa taaagagaaa aggaaaaaat taaaaagaaa atagtgatag
     3601 ctgtgtccat ctcaaagaaa agcccaggag atttccttta attaaccccc ttttaagata
     3661 gaatattagg agaccggaac atatgataca ggaggtactg ggagggtccc tctttgtcaa
     3721 tgttttgtct tggggtgggg agtcgatgtc ttctcaaagt ttcagaaaca ccatccactg
     3781 actgagcatt caagggggaa gaggagaatg gcagccacat ttgttgattg ggtgagtttg
     3841 gggagaaata gacacacaaa ggtcaaacat aacttcctaa ttaacacttc cctccattca
     3901 caattccctt ctcccattct tctctccttt cttttactga aaaaaaccca gtttttcctg
     3961 aaactataaa aagaccccag tatttttaca taatttacac ctcaaagatt agaaaccaga
     4021 aatagagacc tttttcaacc cttccggaag caaagtgcat tatccctcca gccacgtgtc
     4081 tcaaatcttg atgcatcaga atcatctggg tgctttgaaa ttcaagatga ttcctacgag
     4141 ttaccataaa tcaactcaga attccctgga gtggggccca gggatctgta tttctgacaa
     4201 gctcccacag gtgattcctt tccccacagc atttgagaac ttcagctcaa tgacctaatc
     4261 agagtcctgc cattgctaat aactggtctc atttttttca tatatatata tagtattttt
     4321 ggtagagatg ggattttgcc atgttgccca ggctagtatt gaactcctaa gctaagcaat
     4381 cttcctgtct ctgcctccca aaatgttggg attacaggtg taagccactg cacccggctg
     4441 atagctggtt tcatttactc tatttcttga ccactctgat ccattttgaa gtaaaaatgc
     4501 tccaattatt atgctgtttt agaacacggt aagcatgtca tgtgctaatt atggccagtg
     4561 acatcataaa agaaaagtgc attactgaat gctttcaatt tcttataatg atggtaaggt
     4621 ggcatgtcat ggggcctatt tagccccaga catcactcca aagaattcca aacagatata
     4681 gacaagtgcc tttagggccc agatcccttc ccctcaggct gtttacccag ggaataggat
     4741 gtcctgggac aagtttcccc taagtgaagt gttgataagt ctgcttatca gaaagatatt
     4801 actgggggtg tgatatgtag ggcatctaca ttttcttgat aggtagtcat atgaaagctg
     4861 acaaagaaaa aaagggcagt gatgtggtgc aatgtcaaca gacagctgtc ccctgactct
     4921 tgacaaatag gatgacttgc attgctgagc gatgtgatca ccaccaaagg aatggccctc
     4981 tcacatttct tcctgattca catattcagc agggttagct tgtcctcccc tccctcttca
     5041 gcttcccaga cactgagtct ggaatgaaaa ttcacctgcc tctgagttgg ctcctaatgg
     5101 gggtgggagt gttacttcgg ttcccaggtt ggaagattat ctcacccggc cccagctata
     5161 taagctgacc ggtgtggagg ggcccagcag ggccaactcc agggattcct tccacgacag
     5221 aaaaacatac aagactcctt cagccaacat gatggtactg aaagtagagg aactggtatg
     5281 taagatgcat taattttata aaatgaaaac tggttcatct tggtttttat ttgaaaattg
     5341 aaatgccctt tgctttcagg tgtaatgcaa gggaactctg aaaatgtcat atatggaaaa
     5401 aggttgatgt gatgaaacaa gtgaaattgg aaaaaaaaaa tggagctacc agtaatgaat
     5461 tctctgcata tttcctattt aatatcttct cctttggttt tattactaca gtgtggaatc
     5521 acgtgtagtt atcaaaatgt cttagggaag aagtgttatt gaaagaatgt aagcccggaa
     5581 actttacaat aaggcgaaac tcatcaaaag tacctaaagt tgagttttaa ttaagcagag
     5641 aaggtttttg attttcctaa aagaaatgtg attaagcaga ttaaaagtag atttaatctg
     5701 tcaacctaac ccaagctttg atttaaccaa gagagtagga caagcatctg aaggtaattc
     5761 tgggacaatt gtagcagtgt gcatcgcagc ttgagatctg agagtgcact gctcaaaggt
     5821 ggctgttccc aggggagaag gaccaagagc ctcctgcggc attgtctgtg aagaatgacc
     5881 caggacgagg ctgctgcttc tgacgctgcc atcttcttcc ctcataggtc actggaaaga
     5941 agaatggcaa tggggaggca ggggaattcc ttcctgagga tttcagagat ggagagtatg
     6001 aagctgctgt tactttagag aagcaggagg atctgaagac acttctagcc caccctgtga
     6061 ccctggggga gcaacagtgg aaaagcgaga aacaacgaga ggcagaggtg agagccatct
     6121 gtggaatcca ctagtaggat gttggggctg gggtagggaa tggaaatgtc agggaaggag
     6181 aagagagaaa caaacccaat cattaagatg tctctttacc agattctaac ccgtaaagag
     6241 gcaacttgta tggaacaggt tttgggaaat aactctttga caagactatg acctctgaat
     6301 tctgaatcaa tgaataaatg tgctgtgacc atgttttgat tgaaagatac acatgtccag
     6361 tgaattcctg atgttacaca ccatgtagtt aatcccaagc aacggagatc tctttttctc
     6421 aataacatgg tctgtggtcc atagatcatt gtttaactgt ctgctatctg tgttgacaca
     6481 atctgtgttt ctgggtgaat tttccttaat tactaacaca gataaaattt gctttagtta
     6541 gctgtggtcc ctggacagtc tgttttagaa ggctctgctt agtgaaagag aatgacattg
     6601 atatttcaga gcttaacatt tattgttaga ttctttttat catgctcaaa aattaaacca
     6661 agttttgagc ataattttaa aaatccttta aaaatctaag acttgcttat ggcattaatt
     6721 acaaagtcat cacttagaga ccagatcgtg tcctcaattg gtcaagggct gattctacaa
     6781 gcaacagaag taaagatgat ggcaattagc tgaaaattag actcccagat aaatatctga
     6841 ataagaaatc cctaaaatga agtcaaagat ttatataatt tttaaaaaat gtttttgctc
     6901 aaactgttca catgtttatc tcagaccttg cagatttagt ttagacacaa ccagaatgct
     6961 tgtcagtaga actcaccata tttttgaaat acgaatttct tttttagctc aaaaagaaaa
     7021 aactagaaca aagatcaaag cttgaaaatt tagaagacct tgaaataatc attcaactga
     7081 agaaaaggaa aaaatacagg aaaactaaag ttccagttgt aaaggaacca gaacctgaaa
     7141 tcattgtaag ggcttttttt ttggtttcca gtaatacatg tccagtgttg tgctacaggg
     7201 gagcaaatat ctgtggaggg tttgattgaa tgctggcaag ctcacggtaa ctctcatgct
     7261 atatatatat atatatatat atatttattt attttggctt tagacggaac ctgtggatgt
     7321 gcctacgttt ctgaaggctg ctctggagaa taaactgcca gtagtagaaa aattcttgtc
     7381 agacaagaac aatccagatg tttgtgatga ggtaagactc atgcaaagca ctgcaaaatc
     7441 cagctcatta attttatgtt tcttatgctt tactccagtc ttgctaatat agtgccaaag
     7501 tccttccacc tgaaacagtt tccccagctg ttgctgtgta tgccaggagc ctaataggag
     7561 agttcagtgg tccaaaaaat aaatagatat tagatcagtg atacggattg cattgttttt
     7621 tgcactcata tacatctggc tgatttttca gtttttcttt aacttcttag attcttggga
     7681 taagactttt aatgtgggcc aaaaagtcac ctttagagat atattattag catcatcttt
     7741 gattaaaacc aagcacgtca acactagata agaaatctgg agattggagt tcaggggcca
     7801 gttgtaccac tacttggcta tttggttttg agcagctaat ttgcatcctc tgggctgtgg
     7861 tttccttatc tgtaaacatg gggcattgga gtgaaataac gcctaaagtt gttccagctc
     7921 taatagttca ttagcccatt caaataaagc caatttatca gaaatcacta atctttttgt
     7981 attctttccc ccatgaagtg aaattgggga ccgcttctga agttgaacta aaaacatgtc
     8041 tcccattctc ctaaaaatga atggaaactt tttgatagtc tagcaacagt cccagatgca
     8101 agaaagctgt ctgatctgca tggtaatgct acatgaacaa ggaaggtgca agatagaaga
     8161 aacggagatg tcagcattta gatagttttg agcctttaag ttcacactcc tcaacgtagg
     8221 cctttgagcc cttggaaatg tatattggag gaagctcaaa tattagttgc aggataattg
     8281 ttctgattct gcaattttag ttaactttga catttctatt cataaagaag cacttgagtt
     8341 tctatcagtt aggtcatcag aatctccagc ttcatagctc ttaaaagggt ttacacacat
     8401 ttttatattt attgctatct ctgtttaaaa tctctgttct gatagtataa acggacagct
     8461 cttcatagag catgcttgga aggacatttg gcaattgtgg agaagttaat ggaagctgga
     8521 gcccagatcg aattccgtga tatggtaaat atatttcttt gcttgggaat gagccaaaag
     8581 aagtagacta tatgaagctc cggaaaacct ccaatgcaaa accgagctga ttggattgaa
     8641 aattgatctg agagaactag gcaaaagctc atttctccaa ataaaggaaa gttgggagat
     8701 gagagtaggt catgtgaaaa tattttccat acatactgaa aatagaggaa tatttcaggg
     8761 aaaagaagga agtgaaagct gttaaactga attcaatatc ctcatcagcg agttagtcat
     8821 tcattttcga cacttgcctt tcaacagcct tgtccctcca ttgttcacag ggcagcctgc
     8881 ttatggttgg ctgccagcaa catatacgaa ttctctagct gcacacttta tatgatagat
     8941 gccaattgct accaatgaga tttggggcta gactgcatat gaaatgaatt gcatctatgg
     9001 aaagtagctg ctattcagac ctcaataatt caatcactgt gatttctacg aagaccagta
     9061 tgcagcataa tttatgaact gaagattgag ctgggaaaat tctttatgta tttaaatgca
     9121 gctcattttg actttatagc aaagcggcaa cgggatatca aagaaatcca agggacttgg
     9181 ccaaaattga atccaaaaca taaacacatt gaaaaaaaaa tcaagaaaca aaatatgaag
     9241 tttgcatgga aactaaaaat catgagtgtg ggattaaggc caggggcata ccaaccacat
     9301 agatcagtga ggagagggtc tcctaggggt aactatacac gttacaactg tagacacaag
     9361 tgactacagt tgaggtacag aggctgtgct agcaaaaatg agcagaaaac ccacagaagt
     9421 agagaaagag cgacagggac cctagatgag gtgtcagatc cagattaaaa tattttggaa
     9481 gggactactt ttattctgcc aaaattttta aatacatgtg tttagaactt ttgtgtacat
     9541 ttgacaaaag aagttagaag ttccaggcag aggggagttt gactgtgtat tctgcctctt
     9601 attagttgtg tttccttggg ctagaaactt gaactttttg gaacctggtt tttcttatct
     9661 gcaaaatgtg catagcaaca cctacctcaa aatgttgctg gaagaatcaa ggtgtctaaa
     9721 gtgtagcacc atgttggcat gagaaatgtc tcaataagtg gccattctta ttcttttaaa
     9781 acattattag atttattaag agcctcctaa taagacacac atatgcacac acacacacac
     9841 acacatgtaa tttagctaac acatttggta agaaccttcg actccagtta gaattgtcaa
     9901 tctagatggg gacaactcat tattttcacg gatgccctag caaccaggtt ctaattcccc
     9961 agaccacatt ctccttcaca ttgtcgggtc ttccctcccg gtatagcttg aatccacagc
    10021 catccactgg gcaagccgtg gaggaaacct ggatgtttta aaattgttgc tgaataaagg
    10081 agcaaaaatt agcgcccgag ataaggtatt ccttcttctc cttctccctt cattcacccc
    10141 ctccccctcc ctgtccccca tccttctcca cttctcccac tcttccccct ccccctcctc
    10201 cttctccccc acccgccctt ccctcctccc ccacccctcc atctcctaac ctcgcctctc
    10261 cattaaagtc atctggaggc ccatgctgtg tgcaggcacc ctagtgacca cttctccccc
    10321 tcgcacatgt cttggggtct gggacagcct ctgtcctcat tcctagcgaa tcagcagcgt
    10381 tttccaattt tccagttgct cagcacagcg ctgcatgtgg cggtgaggac tggccactat
    10441 gagtgcgcgg agcatcttat cgcctgtgag gcagacctca acgccaaaga cagagtgagt
    10501 agctggacac gctcgggttt cccaaagctt cattgctttt gtatttggaa tcactccccc
    10561 aagcctgggt gcccttgcag gacccacttc ctggcctcag acccaccttg aacctgttga
    10621 ctctgcttct ctaggaagga gataccccgt tgcatgatgc ggtgagactg aaccgctata
    10681 agatgatccg actcctgatt atgtatggcg cggatctcaa catcaagaac tgtgtaagta
    10741 ctggaaacaa gaaacaccgc ttgcaagctt tccaatttcc aggagcattt cttaaatagg
    10801 tgaaacgact cccacaatgg cagtatttga ggggtcttcg atggtctaaa tgcccctgcc
    10861 catttcccca aggacagtgt ttatcttggc taggacccag ttcacatggc cagagatgag
    10921 ggaagtcata gatactgcta tgacctcagt gcctgataca gtgcatagta attcttttac
    10981 aatttggtct tggaaatgaa agatagtcaa aatttgctca tccccacaaa cacctagaag
    11041 tccaatctgc tttggccatt tctgtctgtg caagggctga ggaagttaga aataaaggca
    11101 tccaccattt ccaaaatgtc ctaaaattcc acaagggtca gtgcagccag tgaactaagg
    11161 ttaatcaata tccaatctga gtaattcaga aagtcccttt cctccttaca gcaatgtgaa
    11221 atgtcaccat tttcttccag gggtagctgt gcttttgcct gtattttttt tcagataatt
    11281 tctatccatt ctccacttgg atttgtcttc acatctctca aaataatttc ctatatttag
    11341 gccctgaaaa ttcttgtata agtacatatt aatttaactt catctgtaag cagggaacat
    11401 aaccaacttt tcctcatggt ctcaatttcc agacaaacac catctaatat aagcttaaaa
    11461 aatattgccc agaggaacag gtataaattt ctgaagaaat aattttaaag aagcttttga
    11521 agaatcactt tacaaaaaag agtggggggg gggggaggga aactcagtca tcatataaat
    11581 gcaaataatt ttctcccctt atttgtgttg caaagactga gaggaatatc ttatctttta
    11641 aaacaaatct ggcttggtga caggatcaaa gaatggtgat aaatgaagat tgcttgggat
    11701 gggaaagtgt taacagtagg gcttcctcag tctagatatt ggaattgatc ctatctaata
    11761 tttttttaaa ctatcagaaa aagagcaggt taaatgaaat cttgaaagct gcagaaaatg
    11821 tgaagatttt ttttcaggca gtgagacact accagcagag acaaatagca tacaggttta
    11881 gggagactgt gtaagtagcc agaaaaatca caatataaat ttcaatggag agaagtgcaa
    11941 ggaatttatg gaagagtagc ccaaaatata caaatacggc ttagggttct gaattatcag
    12001 ttagatatta gcatcaggtt tatggaacta ttaatgtcat tgacccaatg gattgatgtt
    12061 tcccccaaag atcaataacc tattgatgcc atcttaagga gattgggagc agcatacaat
    12121 attttctcat tatccaaaac tgtatattca tgtctactga tgattgttcc tagagaaaga
    12181 cactacagag gtggggaagt tccaaaatga aggttatagg gccactaatt taaataccta
    12241 cagatctcat aatctgactg cagactgacc tcactgtgcc gggcagatgg cctaagtgac
    12301 ttcaatgtgt ggctgtcagg gtctgtgcac ataactcttt taaaggtggc ccttccccaa
    12361 cccagtctat gttgctctgt ggaaccatgg gtaccatgtt tttaactctt ctgatttttt
    12421 catagaagtc acaaatccag ctcttggttt ccaactgttg ccaattcata ctaatcttaa
    12481 aaaaaatcta agttctgttt gggtcaaaac aaaacaggtc tctattctgg tttgcatctc
    12541 aaagctgcca atttgcagtc gctgggttaa aaagaaactt ctcaatgaat agagatggaa
    12601 aaattttgga cttctcagat ctatagatga gaattgagag atgacatggt tttaatattt
    12661 ttaaatcttg agacacgtgc ataagggaaa tcaaaatttc gtctcaaaaa ttatttgttc
    12721 acatgtgtca ttgccatcaa ctccaagaaa aatacatttc ctgggagagt ccattgaaaa
    12781 ttctgacaag ttatgaaaaa tctgctccca ggaacagtaa tagtacccaa gcagtaccta
    12841 agtccttaag ccaagttatt gatgcagctc atttaccatc atttcttatc aatcaaagaa
    12901 ctatcattca aatggatagg cactgattct tggtccaaga ggcatgctcc cacctccggg
    12961 agtccattcc acaggatact ggaagatgta tggagacatt ttataaattt caaaatgact
    13021 tgaggtgctc ttgacacata gtgtctaggg acaagggatt ttaccaatac ctgggatggt
    13081 cccacgtgaa aaagattttt gctctaaaat ggcaaaagca tccctctgag aaacagtgaa
    13141 ggactggttt gagtataaac tgcagatcac tcctggtgga aaccataaaa cactgttata
    13201 acatatacct aatccttacc tcatgaaaca cacacagaga atgtgaattt acagatgtca
    13261 cccacctgaa agtcaacttt ccttatctca tttgattagg ctgggaagac gccgatggat
    13321 ctggtgctac actggcagaa tggaaccaaa gcaatattcg acagcctcag agagaactcc
    13381 tacaagacct ctcgcatagc tacattctga ggcaaacgac agactcttaa tcagtaaatg
    13441 ttcactggca ttttgaaggc atggcccaag agaagagaca ctagccataa aatctagttt
    13501 ctatttatca acgtgttgtg aagatgtacc taatgaagtt ttgagaaagc acagggttat
    13561 aggtgtttaa atttccttta gtgaaactct tatttatttt tatgtattcc tgtttattta
    13621 tttactgcca cgctactgat attcagacct tcatgatcat ccatctggtg agcagagctt
    13681 catttgtata taacactttc agagccttcc cacccatagg tagttcttaa accaggtgaa
    13741 agagcaaagt tcaagtgcct acttatgtgt cattcgctca tgtaagagtt tttaagagag
    13801 ggctgattat cacagccctc ttttctcctg aatttttaat gcagaagttt gaatgaagca
    13861 agggaaggca tgtagggaca ggaaaggaaa caatggaagg aaagtgattc tgtgaaaagg
    13921 acagtgaagc cagctatttt acccccaggc tggatttttt tttttttttt tttttttttt
    13981 ttttaccgag tacacagagt acccaagtga agagaacgtc atgagtgtaa gtgcaaatca
    14041 gtggaaggag cggcaaactg ggacatgcag aattgaattt gctcaaaaaa gatgaaagga
    14101 aatgcaaact gtaaatgtat aaatgtatat tgtattgtat gtacatttta tattcataat
    14161 aaaggcaatc aaactctaaa cctctaagtc cttctataag tgtggtggaa atgtcctatg
    14221 tgaaaaaaaa agctatatag gagggttttt tttttccatt gttttccaag ttttgcagat
    14281 tagaaatgtc ccgtacaaca gcactcccag tatttaatat gtatacagat cacctgggga
    14341 tctggttaaa atgcagattt ctgattcagc tggtctcagg tggggcctga gattctgctt
    14401 ttctgacaag ctcccaggtg acaggccacg aaatgccacc accacactga gcagctaggc
    14461 cgagagccat aaagacacaa aggaattcta gcgagctttc agtcccagtg gtgtgtagaa
    14521 agagacccct ggtggtcaga atgatttctg catggtaaac ccgcatttct tacgaagttc
    14581 ccattaaggc ttaactagtg acttttttaa atttaaattt taagttctgg ggtacatgtg
    14641 caggatgtgc agcggtgtta cataaacgtg tgccatggtg gtttgctgca cctatcaacc
    14701 catcacttag gtattaagcc cagcatgcat tagctatttt tcgtaatgct ctccttcctc
    14761 ccaccccacc ccctatacag gtcccagtgt attttgttcc cctccctgtg tccatgtgtt
    14821 ctcattgttc agctcccacc tataagtgag aacatgcggt gtttggtttt ccgctcctgt
    14881 gttaatttgc tgagaataat ggcctctagc tgcatccatg cccctgccaa ggacatgatc
    14941 tcattctttt tatggctgcg ttgtattcca tggtgtatat ctaccatatt ttctttatcc
    15001 agtctattat tgatgggcat ttgggttggt tccatgtctt tgcaattgtg aatagtgctg
    15061 caatgaacat atgcatgcat gtatctttgt agtagaatga tttatattcc tttgggtaca
    15121 tacccaataa tgggattgct aggtcaaatg gtatttctgg ttctagatct ttgaggaatc
    15181 accacaccat tttccacaat ggatgaacta atttacattc ccaccaacag tgtaaaagtg
    15241 ttcctatttt tctgcaacct tgccagcatc tgttatttct tgacttttta agtaactgcc
    15301 attcagactc catccatctg acaaagctct aacatccaga atctacaagg aacttaaatt
    15361 tacaagaaaa aacaacccca tcaaaaaagt gggcaaagca cacgaacaga cacttctcaa
    15421 aagaagatat tcatgtggcc aacaaacatc tggaaaagaa agctcaatat cactgatcat
    15481 tagaaaaatg caaattaact ggagatttaa caattcttgt ggacagggac tggcaatgtc
    15541 aaagacttcc caggagagaa cacacaggtc catgattttt gacctccaga ccaccataat
    15601 aaaactaata tcacaataaa gtgagtcaca attttttttg gttttctagt gcatacaaaa
    15661 gttatgttta cattatcctg tggtttaata attgtgctat agcacgatgt ctaaaaaaca
    15721 ctgtacctac cttaacttaa aaatacttta ttgctaaaaa aaatgctaat gatcatctga
    15781 gccttcagtg agtcataatc gttttaatgg cggagggtct tccctccatg tggatggctg
    15841 ctgactgatg agggtggtag ttgatgaaga ttgggatggc tgtgtcaatt tattgaaaga
    15901 agacaacaat aagcttacca catcaattaa ctctttcata aaagatttat ctgtagcatc
    15961 tgatgctatt tgatagcatg ttactatcaa tagaacatct ttcaaaattg gagtacatcc
    16021 tcgcaaaccc tgttactgct ttattaacta agttgatgta atattcaaaa tccttttttt
    16081 gtcatttcaa caatgtttac agcatcttca ctaggagtag attccatctc aagaaaccac
    16141 ttcctttgct catccatagg aagcaacttc tcagct
//

