myosin, heavy chain 7, cardiac muscle, beta (MYH7) - coding DNA reference sequence

(used for mutation description)

(last modified July 23, 2010)


This file was created to facilitate the description of sequence variants in the MYH7 gene based on a coding DNA reference sequence following the HGVS recommendations. The sequence was taken from NG_007884.1, covering MYH7 transcript NM_000257.2.

Please note that introns are available by clicking on the exon numbers above the sequence.
 (upstream sequence)
                     .         .         .         .      | 02      g.6416
               cacagctctgtcctgctctgtgtctttccctgctgctctcag | gtcc    c.-61

 .         .         .         .         .         .  | 03          g.6929
 cctgcaggccttggcccctttcctcatctgtagacacacttgagtagcccag | gcacagcc    c.-1

          .         .         .         .         .         .       g.6989
 ATGGGAGATTCGGAGATGGCAGTCTTTGGGGCTGCCGCCCCCTACCTGCGCAAGTCAGAG       c.60
 M  G  D  S  E  M  A  V  F  G  A  A  A  P  Y  L  R  K  S  E         p.20

          .         .         .         .         .         .       g.7049
 AAGGAGCGGCTAGAAGCGCAGACCAGGCCTTTTGACCTCAAGAAGGATGTCTTCGTGCCT       c.120
 K  E  R  L  E  A  Q  T  R  P  F  D  L  K  K  D  V  F  V  P         p.40

          .         .         .         .         .         .       g.7109
 GATGACAAACAGGAGTTTGTCAAGGCCAAGATCGTGTCTCGAGAGGGTGGCAAAGTCACT       c.180
 D  D  K  Q  E  F  V  K  A  K  I  V  S  R  E  G  G  K  V  T         p.60

          .         .  | 04      .         .         .         .    g.7473
 GCCGAGACCGAGTATGGCAAG | ACAGTGACCGTGAAGGAGGACCAGGTGATGCAGCAGAAC    c.240
 A  E  T  E  Y  G  K   | T  V  T  V  K  E  D  Q  V  M  Q  Q  N      p.80

          .         .         .         .         .         .       g.7533
 CCACCCAAGTTCGACAAAATCGAGGACATGGCCATGCTGACCTTCCTGCATGAGCCCGCG       c.300
 P  P  K  F  D  K  I  E  D  M  A  M  L  T  F  L  H  E  P  A         p.100

          .         .         .         .      | 05  .         .    g.7881
 GTGCTCTACAACCTCAAGGATCGCTACGGCTCCTGGATGATCTAC | ACCTACTCGGGCCTC    c.360
 V  L  Y  N  L  K  D  R  Y  G  S  W  M  I  Y   | T  Y  S  G  L      p.120

          .         .         .         .         .         .       g.7941
 TTCTGTGTCACCGTCAACCCTTACAAGTGGCTGCCGGTGTACACTCCTGAGGTGGTGGCT       c.420
 F  C  V  T  V  N  P  Y  K  W  L  P  V  Y  T  P  E  V  V  A         p.140

          .         .         .         .         .         .       g.8001
 GCCTACCGGGGCAAGAAGAGGAGCGAGGCCCCGCCCCACATCTTCTCCATCTCCGACAAC       c.480
 A  Y  R  G  K  K  R  S  E  A  P  P  H  I  F  S  I  S  D  N         p.160

          .         .   | 06     .         .         . | 07       . g.8802
 GCCTATCAGTACATGCTGACAG | ACAGAGAAAACCAGTCCATCCTGATCAC | CGGAGAATCC c.540
 A  Y  Q  Y  M  L  T  D |   R  E  N  Q  S  I  L  I  T  |  G  E  S   p.180

          .         .         .         .         .         .       g.8862
 GGAGCAGGGAAGACAGTCAACACCAAGAGGGTCATCCAGTACTTTGCTGTTATTGCAGCC       c.600
 G  A  G  K  T  V  N  T  K  R  V  I  Q  Y  F  A  V  I  A  A         p.200

          .         .         .          | 08        .         .    g.9005
 ATTGGGGACCGCAGCAAGAAGGACCAGAGCCCGGGCAAG | GGCACCCTGGAGGACCAGATC    c.660
 I  G  D  R  S  K  K  D  Q  S  P  G  K   | G  T  L  E  D  Q  I      p.220

          .         .         .         .         .         .       g.9065
 ATCCAGGCCAACCCTGCTCTGGAGGCCTTTGGCAATGCCAAGACCGTCCGGAACGACAAC       c.720
 I  Q  A  N  P  A  L  E  A  F  G  N  A  K  T  V  R  N  D  N         p.240

          .   | 09     .         .         .         .         .    g.9228
 TCCTCCCGCTTC | GGGAAATTCATTCGAATTCATTTTGGGGCAACAGGAAAGTTGGCATCT    c.780
 S  S  R  F   | G  K  F  I  R  I  H  F  G  A  T  G  K  L  A  S      p.260

          .       | 10 .         .         .         .         .    g.9706
 GCAGACATAGAGACCT | ATCTTCTGGAAAAATCCAGAGTTATTTTCCAGCTGAAAGCAGAG    c.840
 A  D  I  E  T  Y |   L  L  E  K  S  R  V  I  F  Q  L  K  A  E      p.280

          .         .         .         .         .      | 11  .    g.10003
 AGAGATTATCACATTTTCTACCAAATCCTGTCTAACAAAAAGCCTGAGCTGCTGG | ACATG    c.900
 R  D  Y  H  I  F  Y  Q  I  L  S  N  K  K  P  E  L  L  D |   M      p.300

          .         .         .         .         .         .       g.10063
 CTGCTGATCACCAACAACCCCTACGATTATGCATTCATCTCCCAAGGAGAGACCACCGTG       c.960
 L  L  I  T  N  N  P  Y  D  Y  A  F  I  S  Q  G  E  T  T  V         p.320

          .         .         .          | 12        .         .    g.10769
 GCCTCCATTGATGACGCTGAGGAGCTCATGGCCACTGAT | AACGCTTTTGATGTGCTGGGC    c.1020
 A  S  I  D  D  A  E  E  L  M  A  T  D   | N  A  F  D  V  L  G      p.340

          .         .         .         .         .         .       g.10829
 TTCACTTCAGAGGAGAAAAACTCCATGTATAAGCTGACAGGCGCCATCATGCACTTTGGA       c.1080
 F  T  S  E  E  K  N  S  M  Y  K  L  T  G  A  I  M  H  F  G         p.360

          .         .         .         .         .         | 13    g.11316
 AACATGAAGTTCAAGCTGAAGCAGCGGGAGGAGCAGGCGGAGCCAGACGGCACTGAAG | AG    c.1140
 N  M  K  F  K  L  K  Q  R  E  E  Q  A  E  P  D  G  T  E  E |       p.380

          .         .         .         .         .         .       g.11376
 GCTGACAAGTCTGCCTACCTCATGGGGCTGAACTCAGCCGACCTGCTCAAGGGGCTGTGC       c.1200
 A  D  K  S  A  Y  L  M  G  L  N  S  A  D  L  L  K  G  L  C         p.400

          .         .         .         .         .        | 14.    g.11560
 CACCCTCGGGTGAAAGTGGGCAATGAGTACGTCACCAAGGGGCAGAATGTCCAGCAG | GTG    c.1260
 H  P  R  V  K  V  G  N  E  Y  V  T  K  G  Q  N  V  Q  Q   | V      p.420

          .         .         .         .         .         .       g.11620
 ATATATGCCACTGGGGCACTGGCCAAGGCAGTGTATGAGAGGATGTTCAACTGGATGGTG       c.1320
 I  Y  A  T  G  A  L  A  K  A  V  Y  E  R  M  F  N  W  M  V         p.440

          .         .         .         .         .         .       g.11680
 ACGCGCATCAATGCCACCCTGGAGACCAAGCAGCCACGCCAGTACTTCATAGGAGTCCTG       c.1380
 T  R  I  N  A  T  L  E  T  K  Q  P  R  Q  Y  F  I  G  V  L         p.460

          .         .        | 15.         .         .         .    g.12024
 GACATCGCTGGCTTCGAGATCTTCGAT | TTCAACAGCTTTGAGCAGCTCTGCATCAACTTC    c.1440
 D  I  A  G  F  E  I  F  D   | F  N  S  F  E  Q  L  C  I  N  F      p.480

          .         .         .         .         .         .       g.12084
 ACCAACGAGAAGCTGCAGCAGTTCTTCAACCACCACATGTTTGTGCTGGAGCAGGAGGAG       c.1500
 T  N  E  K  L  Q  Q  F  F  N  H  H  M  F  V  L  E  Q  E  E         p.500

          .         .         .         .         .         .       g.12144
 TACAAGAAGGAGGGCATCGAGTGGACATTCATTGACTTTGGCATGGACCTGCAGGCCTGC       c.1560
 Y  K  K  E  G  I  E  W  T  F  I  D  F  G  M  D  L  Q  A  C         p.520

          .         | 16         .         .         .         .    g.12809
 ATTGACCTCATCGAGAAG | CCCATGGGCATCATGTCCATCCTGGAAGAGGAGTGCATGTTC    c.1620
 I  D  L  I  E  K   | P  M  G  I  M  S  I  L  E  E  E  C  M  F      p.540

          .         .         .         .         .         .       g.12869
 CCCAAGGCCACCGACATGACCTTCAAGGCCAAGCTGTTTGACAACCACCTGGGCAAATCC       c.1680
 P  K  A  T  D  M  T  F  K  A  K  L  F  D  N  H  L  G  K  S         p.560

          .         .         .         .         .         .       g.12929
 GCCAACTTCCAGAAGCCACGCAATATCAAGGGGAAGCCTGAAGCCCACTTCTCCCTGATC       c.1740
 A  N  F  Q  K  P  R  N  I  K  G  K  P  E  A  H  F  S  L  I         p.580

          .         .         .         .         .         .       g.12989
 CACTATGCCGGCATCGTGGACTACAACATCATTGGCTGGCTGCAGAAGAACAAGGATCCT       c.1800
 H  Y  A  G  I  V  D  Y  N  I  I  G  W  L  Q  K  N  K  D  P         p.600

          .         .         .         .         .         .       g.13049
 CTCAATGAGACTGTCGTGGGCTTGTATCAGAAGTCTTCCCTCAAGCTGCTCAGCACCCTG       c.1860
 L  N  E  T  V  V  G  L  Y  Q  K  S  S  L  K  L  L  S  T  L         p.620

          .         .         | 17         .         .         .    g.13386
 TTTGCCAACTATGCTGGGGCTGATGCGC | CTATTGAGAAGGGCAAAGGCAAGGCCAAGAAA    c.1920
 F  A  N  Y  A  G  A  D  A  P |   I  E  K  G  K  G  K  A  K  K      p.640

          .         .         .       | 18 .         .         .    g.13821
 GGCTCGTCCTTTCAGACTGTGTCAGCTCTGCACAGG | GAAAATCTGAACAAGCTGATGACC    c.1980
 G  S  S  F  Q  T  V  S  A  L  H  R   | E  N  L  N  K  L  M  T      p.660

          .         .         .         .         .         .       g.13881
 AACTTGCGCTCCACCCATCCCCACTTTGTACGTTGTATCATCCCTAATGAGACAAAGTCT       c.2040
 N  L  R  S  T  H  P  H  F  V  R  C  I  I  P  N  E  T  K  S         p.680

      | 19   .         .         .         .         .         .    g.14636
 CCAG | GGGTGATGGACAACCCCCTGGTCATGCACCAGCTGCGCTGCAATGGTGTGCTGGAG    c.2100
 P  G |   V  M  D  N  P  L  V  M  H  Q  L  R  C  N  G  V  L  E      p.700

          .         .         .         .         .         .       g.14696
 GGCATCCGCATCTGCAGGAAAGGCTTCCCCAACCGCATCCTCTACGGGGACTTCCGGCAG       c.2160
 G  I  R  I  C  R  K  G  F  P  N  R  I  L  Y  G  D  F  R  Q         p.720

    | 20     .         .         .         .         .         .    g.14901
 AG | GTATCGCATCCTGAACCCAGCGGCCATCCCTGAGGGACAGTTCATTGATAGCAGGAAG    c.2220
 R  |  Y  R  I  L  N  P  A  A  I  P  E  G  Q  F  I  D  S  R  K      p.740

          .         .         .         .         .         .       g.14961
 GGGGCAGAGAAGCTGCTCAGCTCCCTGGACATTGATCACAACCAGTACAAGTTTGGCCAC       c.2280
 G  A  E  K  L  L  S  S  L  D  I  D  H  N  Q  Y  K  F  G  H         p.760

        | 21 .         .         .         .         .         .    g.15297
 ACCAAG | GTGTTCTTCAAGGCCGGGCTGCTGGGGCTGCTGGAGGAAATGAGGGACGAGAGG    c.2340
 T  K   | V  F  F  K  A  G  L  L  G  L  L  E  E  M  R  D  E  R      p.780

          .         .         .         .         .         .       g.15357
 CTGAGCCGCATCATCACGCGTATCCAGGCCCAGTCCCGAGGTGTGCTCGCCAGAATGGAG       c.2400
 L  S  R  I  I  T  R  I  Q  A  Q  S  R  G  V  L  A  R  M  E         p.800

          .         .    | 22    .         .         .         .    g.15674
 TACAAAAAGCTGCTGGAACGTAG | AGACTCCCTGCTGGTAATCCAGTGGAACATTCGGGCC    c.2460
 Y  K  K  L  L  E  R  R  |  D  S  L  L  V  I  Q  W  N  I  R  A      p.820

          .         .         .         .         .         .       g.15734
 TTCATGGGGGTCAAGAATTGGCCCTGGATGAAGCTCTACTTCAAGATCAAGCCGCTGCTG       c.2520
 F  M  G  V  K  N  W  P  W  M  K  L  Y  F  K  I  K  P  L  L         p.840

          .         .         .         .         .         .       g.15794
 AAGAGTGCAGAAAGAGAGAAGGAGATGGCCTCCATGAAGGAGGAGTTCACACGCCTCAAA       c.2580
 K  S  A  E  R  E  K  E  M  A  S  M  K  E  E  F  T  R  L  K         p.860

          .         .         .         .         .         .       g.15854
 GAGGCGCTAGAGAAGTCCGAGGCTCGCCGCAAGGAGCTGGAGGAGAAGATGGTGTCCCTG       c.2640
 E  A  L  E  K  S  E  A  R  R  K  E  L  E  E  K  M  V  S  L         p.880

          .         .         .          | 23        .         .    g.16533
 CTGCAGGAGAAGAATGACCTGCAGCTCCAAGTGCAGGCG | GAACAAGACAACCTGGCAGAT    c.2700
 L  Q  E  K  N  D  L  Q  L  Q  V  Q  A   | E  Q  D  N  L  A  D      p.900

          .         .         .         .         .         .       g.16593
 GCTGAGGAGCGCTGTGATCAGCTGATCAAAAACAAGATTCAGCTGGAGGCCAAGGTGAAG       c.2760
 A  E  E  R  C  D  Q  L  I  K  N  K  I  Q  L  E  A  K  V  K         p.920

          .         .         .         .         .         .       g.16653
 GAGATGAACGAGAGGCTGGAGGATGAGGAGGAGATGAATGCTGAGCTCACTGCCAAGAAG       c.2820
 E  M  N  E  R  L  E  D  E  E  E  M  N  A  E  L  T  A  K  K         p.940

          .         .         .         .         .         .       g.16713
 CGCAAGCTGGAAGATGAGTGCTCAGAGCTCAAAAGGGACATCGATGATCTGGAGCTGACA       c.2880
 R  K  L  E  D  E  C  S  E  L  K  R  D  I  D  D  L  E  L  T         p.960

          .         .         .         .   | 24     .         .    g.16956
 CTGGCCAAAGTGGAGAAGGAGAAACACGCAACAGAGAACAAG | GTGAAAAACCTGACAGAG    c.2940
 L  A  K  V  E  K  E  K  H  A  T  E  N  K   | V  K  N  L  T  E      p.980

          .         .         .         .         .         .       g.17016
 GAGATGGCTGGGCTGGATGAGATCATTGCCAAGCTGACCAAGGAGAAGAAAGCTCTGCAA       c.3000
 E  M  A  G  L  D  E  I  I  A  K  L  T  K  E  K  K  A  L  Q         p.1000

          .         .         .         .         .         .       g.17076
 GAGGCCCACCAACAGGCTCTGGATGACCTTCAGGCCGAGGAGGACAAGGTCAACACCCTG       c.3060
 E  A  H  Q  Q  A  L  D  D  L  Q  A  E  E  D  K  V  N  T  L         p.1020

          .         .         .          | 25        .         .    g.18357
 ACTAAGGCCAAAGTCAAGCTGGAGCAGCAAGTGGATGAT | CTGGAAGGATCCCTGGAGCAA    c.3120
 T  K  A  K  V  K  L  E  Q  Q  V  D  D   | L  E  G  S  L  E  Q      p.1040

          .         .         .         .         .         .       g.18417
 GAGAAGAAGGTGCGCATGGACCTGGAGCGAGCGAAGCGGAAGCTGGAGGGCGACCTGAAG       c.3180
 E  K  K  V  R  M  D  L  E  R  A  K  R  K  L  E  G  D  L  K         p.1060

          .         .         .         .         .         .       g.18477
 CTGACCCAGGAGAGCATCATGGACCTGGAGAATGACAAGCAGCAGCTGGATGAGCGGCTG       c.3240
 L  T  Q  E  S  I  M  D  L  E  N  D  K  Q  Q  L  D  E  R  L         p.1080

       | 26  .         .         .         .         .         .    g.19668
 AAAAA | AAAAGACTTTGAGCTGAATGCTCTCAACGCAAGGATTGAGGATGAACAGGCCCTC    c.3300
 K  K  |  K  D  F  E  L  N  A  L  N  A  R  I  E  D  E  Q  A  L      p.1100

          .         .         .       | 27 .         .         .    g.20451
 GGCAGCCAGCTGCAGAAGAAGCTCAAGGAGCTTCAG | GCACGCATCGAGGAGCTGGAGGAG    c.3360
 G  S  Q  L  Q  K  K  L  K  E  L  Q   | A  R  I  E  E  L  E  E      p.1120

          .         .         .         .         .         .       g.20511
 GAGCTGGAGGCCGAGCGCACCGCCAGGGCTAAGGTGGAGAAGCTGCGCTCAGACCTGTCT       c.3420
 E  L  E  A  E  R  T  A  R  A  K  V  E  K  L  R  S  D  L  S         p.1140

          .         .         .         .         .         .       g.20571
 CGGGAGCTGGAGGAGATCAGCGAGCGGCTGGAAGAGGCCGGCGGGGCCACGTCCGTGCAG       c.3480
 R  E  L  E  E  I  S  E  R  L  E  E  A  G  G  A  T  S  V  Q         p.1160

          .         .         .         .         .         .       g.20631
 ATCGAGATGAACAAGAAGCGCGAGGCCGAGTTCCAGAAGATGCGGCGGGACCTGGAGGAG       c.3540
 I  E  M  N  K  K  R  E  A  E  F  Q  K  M  R  R  D  L  E  E         p.1180

          .         .         .         .         .         .       g.20691
 GCCACGCTGCAGCACGAGGCCACTGCCGCGGCCCTGCGCAAGAAGCACGCCGACAGCGTG       c.3600
 A  T  L  Q  H  E  A  T  A  A  A  L  R  K  K  H  A  D  S  V         p.1200

          .         .         .         .         .         .       g.20751
 GCCGAGCTGGGCGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAAGCTGGAGAAGGAG       c.3660
 A  E  L  G  E  Q  I  D  N  L  Q  R  V  K  Q  K  L  E  K  E         p.1220

          .         .         .         .         .         .       g.20811
 AAGAGCGAGTTCAAGCTGGAGCTGGATGACGTCACCTCCAACATGGAGCAGATCATCAAG       c.3720
 K  S  E  F  K  L  E  L  D  D  V  T  S  N  M  E  Q  I  I  K         p.1240

        | 28 .         .         .         .         .         .    g.21106
 GCCAAG | GCTAACCTGGAGAAGATGTGCCGGACCTTGGAAGACCAGATGAATGAGCACCGG    c.3780
 A  K   | A  N  L  E  K  M  C  R  T  L  E  D  Q  M  N  E  H  R      p.1260

          .         .         .         .         .         .       g.21166
 AGCAAGGCGGAGGAGACCCAGCGTTCTGTCAACGACCTCACCAGCCAGCGGGCCAAGTTG       c.3840
 S  K  A  E  E  T  Q  R  S  V  N  D  L  T  S  Q  R  A  K  L         p.1280

          .    | 29    .         .         .         .         .    g.21413
 CAAACCGAGAATG | GTGAGCTGTCCCGGCAGCTGGATGAGAAGGAGGCACTGATCTCCCAG    c.3900
 Q  T  E  N  G |   E  L  S  R  Q  L  D  E  K  E  A  L  I  S  Q      p.1300

          .         .         .         .         .         .       g.21473
 CTGACCCGAGGCAAGCTCACCTACACCCAGCAGCTGGAGGACCTCAAGAGGCAGCTGGAG       c.3960
 L  T  R  G  K  L  T  Y  T  Q  Q  L  E  D  L  K  R  Q  L  E         p.1320

          .   | 30     .         .         .         .         .    g.22303
 GAGGAGGTTAAG | GCGAAGAACGCCCTGGCCCACGCACTGCAGTCGGCCCGGCATGACTGC    c.4020
 E  E  V  K   | A  K  N  A  L  A  H  A  L  Q  S  A  R  H  D  C      p.1340

          .         .         .         .         .         .       g.22363
 GACCTGCTGCGGGAGCAGTACGAGGAGGAGACGGAGGCCAAGGCCGAGCTGCAGCGCGTC       c.4080
 D  L  L  R  E  Q  Y  E  E  E  T  E  A  K  A  E  L  Q  R  V         p.1360

          .         .         .         .         .         .       g.22423
 CTTTCCAAGGCCAACTCGGAGGTGGCCCAGTGGAGGACCAAGTATGAGACGGACGCCATT       c.4140
 L  S  K  A  N  S  E  V  A  Q  W  R  T  K  Y  E  T  D  A  I         p.1380

          .         .          | 31        .         .         .    g.23006
 CAGCGGACTGAGGAGCTCGAGGAGGCCAA | GAAGAAGCTGGCCCAGCGGCTGCAGGAAGCT    c.4200
 Q  R  T  E  E  L  E  E  A  K  |  K  K  L  A  Q  R  L  Q  E  A      p.1400

          .         .         .         .         .         .       g.23066
 GAGGAGGCCGTGGAGGCTGTTAATGCCAAGTGCTCCTCGCTGGAGAAGACCAAGCACCGG       c.4260
 E  E  A  V  E  A  V  N  A  K  C  S  S  L  E  K  T  K  H  R         p.1420

          .         .         .         .         .         .       g.23126
 CTACAGAATGAGATCGAGGACTTGATGGTGGACGTAGAGCGCTCCAATGCTGCTGCTGCA       c.4320
 L  Q  N  E  I  E  D  L  M  V  D  V  E  R  S  N  A  A  A  A         p.1440

          .         .         .    | 32    .         .         .    g.23370
 GCCCTGGACAAGAAGCAGAGGAACTTCGACAAG | ATCCTGGCCGAGTGGAAGCAGAAGTAT    c.4380
 A  L  D  K  K  Q  R  N  F  D  K   | I  L  A  E  W  K  Q  K  Y      p.1460

          .         .         .         .         .         .       g.23430
 GAGGAGTCGCAGTCGGAGCTGGAGTCCTCGCAGAAGGAGGCTCGCTCCCTCAGCACAGAG       c.4440
 E  E  S  Q  S  E  L  E  S  S  Q  K  E  A  R  S  L  S  T  E         p.1480

          .         .         .         .         .         .       g.23490
 CTCTTCAAACTCAAGAACGCCTATGAGGAGTCCCTGGAACATCTGGAGACCTTCAAGCGG       c.4500
 L  F  K  L  K  N  A  Y  E  E  S  L  E  H  L  E  T  F  K  R         p.1500

          .          | 33        .         .         .         .    g.23710
 GAGAACAAAAACCTGCAGG | AGGAGATCTCCGACTTGACTGAGCAGTTGGGTTCCAGCGGA    c.4560
 E  N  K  N  L  Q  E |   E  I  S  D  L  T  E  Q  L  G  S  S  G      p.1520

          .         .         .         .         .         .       g.23770
 AAGACTATCCATGAGCTGGAGAAGGTCCGAAAGCAGCTGGAGGCCGAGAAGATGGAGCTG       c.4620
 K  T  I  H  E  L  E  K  V  R  K  Q  L  E  A  E  K  M  E  L         p.1540

          .         .     | 34   .         .         .         .    g.24385
 CAGTCAGCCCTGGAGGAGGCCGAG | GCCTCCCTGGAGCACGAGGAGGGCAAGATCCTCCGG    c.4680
 Q  S  A  L  E  E  A  E   | A  S  L  E  H  E  E  G  K  I  L  R      p.1560

          .         .         .         .         .         .       g.24445
 GCCCAGCTGGAGTTCAACCAGATCAAGGCAGAGATCGAGCGGAAGCTGGCAGAGAAGGAC       c.4740
 A  Q  L  E  F  N  Q  I  K  A  E  I  E  R  K  L  A  E  K  D         p.1580

          .         .         .         .         .         .       g.24505
 GAGGAGATGGAACAGGCCAAGCGCAACCACCTGCGGGTGGTGGACTCGCTGCAGACCTCC       c.4800
 E  E  M  E  Q  A  K  R  N  H  L  R  V  V  D  S  L  Q  T  S         p.1600

          .         .         .         .         .         .       g.24565
 CTGGACGCAGAGACACGCAGCCGCAACGAGGCCCTGAGGGTGAAGAAGAAGATGGAAGGA       c.4860
 L  D  A  E  T  R  S  R  N  E  A  L  R  V  K  K  K  M  E  G         p.1620

          .         .         .         .         .         .       g.24625
 GACCTCAATGAGATGGAGATCCAGCTCAGCCACGCCAACCGCATGGCCGCCGAGGCCCAG       c.4920
 D  L  N  E  M  E  I  Q  L  S  H  A  N  R  M  A  A  E  A  Q         p.1640

          .         .         .    | 35    .         .         .    g.24856
 AAGCAAGTCAAGAGCCTCCAGAGCTTGTTGAAG | GACACCCAGATTCAGCTGGACGATGCA    c.4980
 K  Q  V  K  S  L  Q  S  L  L  K   | D  T  Q  I  Q  L  D  D  A      p.1660

          .         .         .         .         .         .       g.24916
 GTCCGTGCCAACGACGACCTGAAGGAGAACATCGCCATCGTGGAGCGGCGCAACAACCTG       c.5040
 V  R  A  N  D  D  L  K  E  N  I  A  I  V  E  R  R  N  N  L         p.1680

          .         .         .         .         .         .       g.24976
 CTGCAGGCTGAGCTGGAGGAGTTGCGTGCCGTGGTGGAGCAGACAGAGCGGTCCCGGAAG       c.5100
 L  Q  A  E  L  E  E  L  R  A  V  V  E  Q  T  E  R  S  R  K         p.1700

          .         .         .         .         .        | 36.    g.25158
 CTGGCGGAGCAGGAGCTGATTGAGACTAGTGAGCGGGTGCAGCTGCTGCATTCCCAG | AAC    c.5160
 L  A  E  Q  E  L  I  E  T  S  E  R  V  Q  L  L  H  S  Q   | N      p.1720

          .         .         .         .         .         .       g.25218
 ACCAGCCTCATCAACCAGAAGAAGAAGATGGATGCTGACCTGTCCCAGCTCCAGACTGAA       c.5220
 T  S  L  I  N  Q  K  K  K  M  D  A  D  L  S  Q  L  Q  T  E         p.1740

          .         .         .         .         .         .       g.25278
 GTGGAGGAGGCAGTGCAGGAGTGCAGGAATGCTGAGGAGAAGGCCAAGAAGGCCATCACG       c.5280
 V  E  E  A  V  Q  E  C  R  N  A  E  E  K  A  K  K  A  I  T         p.1760

     | 37    .         .         .         .         .         .    g.25448
 GAT | GCCGCCATGATGGCAGAGGAGCTGAAGAAGGAGCAGGACACCAGCGCCCACCTGGAG    c.5340
 D   | A  A  M  M  A  E  E  L  K  K  E  Q  D  T  S  A  H  L  E      p.1780

          .         .         .         .         .         .       g.25508
 CGCATGAAGAAGAACATGGAACAGACCATTAAGGACCTGCAGCACCGGCTGGACGAAGCC       c.5400
 R  M  K  K  N  M  E  Q  T  I  K  D  L  Q  H  R  L  D  E  A         p.1800

          .         .         .         .         .         .       g.25568
 GAGCAGATCGCCCTCAAGGGCGGCAAGAAGCAGCTGCAGAAGCTGGAAGCGCGGGTGCGG       c.5460
 E  Q  I  A  L  K  G  G  K  K  Q  L  Q  K  L  E  A  R  V  R         p.1820

          .         .         .         .         .         .       g.25628
 GAGCTGGAGAATGAGCTGGAGGCCGAGCAGAAGCGCAACGCAGAGTCGGTGAAGGGCATG       c.5520
 E  L  E  N  E  L  E  A  E  Q  K  R  N  A  E  S  V  K  G  M         p.1840

          .         .         .          | 38        .         .    g.26580
 AGGAAGAGCGAGCGGCGCATCAAGGAGCTCACCTACCAG | ACGGAGGAGGACAGGAAAAAC    c.5580
 R  K  S  E  R  R  I  K  E  L  T  Y  Q   | T  E  E  D  R  K  N      p.1860

          .         .         .         .         .         .       g.26640
 CTGCTGCGGCTGCAGGACCTGGTAGACAAGCTGCAGCTAAAGGTCAAGGCCTACAAGCGC       c.5640
 L  L  R  L  Q  D  L  V  D  K  L  Q  L  K  V  K  A  Y  K  R         p.1880

          .      | 39  .         .         .         .         .    g.26813
 CAGGCCGAGGAGGCG | GAGGAGCAAGCCAACACCAACCTGTCCAAGTTCCGCAAGGTGCAG    c.5700
 Q  A  E  E  A   | E  E  Q  A  N  T  N  L  S  K  F  R  K  V  Q      p.1900

          .         .         .         .         .         .       g.26873
 CACGAGCTGGATGAGGCAGAGGAGCGGGCGGACATCGCCGAGTCCCAGGTCAACAAGCTG       c.5760
 H  E  L  D  E  A  E  E  R  A  D  I  A  E  S  Q  V  N  K  L         p.1920

          .         .         . | 40       .                        g.27820
 CGGGCCAAGAGCCGTGACATTGGCACGAAG | GGCTTGAATGAGGAGTAG                c.5808
 R  A  K  S  R  D  I  G  T  K   | G  L  N  E  E  X                  p.1935

          .         .         .         .         .         .       g.27880
 ctttgccacatcttgatctgctcagccctggaggtgccagcaaagccccatgctggagcc       c.*60

          .         .         .         .         .                 g.27936
 tgtgtaacagctccttgggaggaagcagaataaagcaattttccttgaagccgaga           c.*116

 (downstream sequence)
Legend:
Nucleotide numbering (following the rules of the HGVS for a 'Coding DNA Reference Sequence') is indicated at the right of the sequence, counting the A of the ATG translation initiating Methionine as 1. Every 10th nucleotide is indicated by a "." above the sequence. The Myosin, heavy chain 7, cardiac muscle, beta protein sequence is shown below the coding DNA sequence, with numbering indicated at the right starting with 1 for the translation initiating Methionine. Every 10th amino acid is shown in bold. The position of introns is indicated by a vertical line, splitting the two exons. The start of the first exon (transcription initiation site) is indicated by a '\', the end of the last exon (poly-A addition site) by a '/'. The exon number is indicated above the first nucleotide(s) of the exon. To aid the description of frame shift mutations, all stop codons in the +1 frame are shown in bold while all stop codons in the +2 frame are underlined.

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